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  3. THALODA 50 MG TABLETS

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
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Composition :

THALIDOMIDE-50MG

Manufacturer/Marketer :

Alkem Laboratories Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About THALODA 50 MG TABLETS

THALODA 50 MG TABLETS belongs to the group of medicines called immunomodulatory agents used to treat multiple myeloma. THALODA 50 MG TABLETS is also used to treat and prevent symptoms of erythema nodosum leprosum (ENL) and as maintenance therapy for prevention and suppression of erythema nodosum leprosum recurrence. Multiple myeloma is a type of cancer that affects a type of white blood cells called plasma cells. ENL is an immune-mediated inflammatory complication of leprosy.
 
THALODA 50 MG TABLETS contains ‘Thalidomide’, which works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Thereby, THALODA 50 MG TABLETS helps treat multiple myeloma.

You are advised to take THALODA 50 MG TABLETS for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as constipation, dizziness, sleepiness, tiredness, tremor, dysaesthesia (abnormal sensation), low blood cell count, nausea, vomiting, swelling of hands and feet. Speak with your doctor if you experience any of these side effects persistently.
 
Do not take THALODA 50 MG TABLETS if you are pregnant as it might cause severe birth defects or the death of an unborn baby. Avoid taking THALODA 50 MG TABLETS if you are breastfeeding. THALODA 50 MG TABLETS may cause dizziness, sleepiness, and blurred vision, so drive only if you are alert. THALODA 50 MG TABLETS is not recommended for children below 18 years as safety and effectiveness have not been established. Avoid consuming alcohol along with THALODA 50 MG TABLETS as it could lead to increased dizziness. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of THALODA 50 MG TABLETS

Multiple myeloma, Erythema Nodosum Leprosum (ENL)

Directions for Use

Swallow THALODA 50 MG TABLETS as a whole with water; do not crush or chew it.

Medicinal Benefits

THALODA 50 MG TABLETS belongs to the group of medicines called immunomodulatory agents used to treat multiple myeloma. THALODA 50 MG TABLETS works by helping the body’s immune system and directly attacks cancer. It stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Thereby, THALODA 50 MG TABLETS helps treat multiple myeloma. THALODA 50 MG TABLETS is also used to treat and prevent skin symptoms of erythema nodosum leprosum and as maintenance therapy for prevention and suppression of erythema nodosum leprosum recurrence.

Storage

Keep THALODA 50 MG TABLETS out of reach and sight of children.
Side effects of Thaloda 50 Mg Tablets
Managing Medication-Triggered Hypocalcemia (Calcium deficiency or Low Calcium Levels In Blood): A Step-by-Step Guide:
  • Consult Your Doctor: If you experience symptoms such as muscle cramps, tingling, numbness, weakness, or spasms, which may indicate low calcium levels (hypocalcemia), consult your doctor to determine if your medication is the cause.
  • Your doctor will assess your medication regimen and adjust it if necessary to minimize the risk of hypocalcemia.
  • Your doctor may order blood tests to check your calcium levels and monitor for any changes.
  • To manage hypocalcemia, your doctor recommends dietary and lifestyle modifications. This may include increasing your intake of calcium-rich foods to support bone health and calcium levels. If necessary, your doctor may also prescribe calcium and vitamin D supplements to help stabilize your calcium levels.
  • If your condition does not improve or worsens, consult your doctor immediately for further evaluation and treatment.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
  • Avoid contact with people who are sick.
  • Wash your hands regularly with soap and water.
  • Avoid unpasteurized dairy products.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
  • Muscle weakness can be due to tiredness, which can be managed by eating often.
  • Observe your movements and understand why the muscle is weakening.
  • Regularly do strengthening exercises to improve blood flow throughout the body and reduce weakness.
  • Sleep well and give enough rest to your body.
  • Take a balanced diet, quit smoking and intake of alcohol.
  • Practice yoga and meditation to improve inner strength and stay healthy.
  • Confusion is a major psychotic disorder that needs immediate medical attention.
  • Acknowledge your experience and put effort to control confusion.
  • Avoid smoking and alcohol intake as it can worsen the condition and increase your confusion.
  • Practice meditation and yoga to avoid anxiety, which can be one of the leading causes.
  • Talk to your dietician and consume food that can improve your mental health.

Drug Warnings

Do not take THALODA 50 MG TABLETS if you are allergic to any of its components. Inform your doctor if you have/had blood clots, heart attack, neuropathy, slow heart rate, high blood pressure, low blood pressure, infections, viral infection, HIV, hepatitis B, epilepsy, liver or kidney problems. Do not take THALODA 50 MG TABLETS if you are pregnant, as it might cause severe birth defects or the death of the unborn baby. Avoid taking THALODA 50 MG TABLETS if you are breastfeeding, as it is not unknown if it passes into breastmilk. THALODA 50 MG TABLETS may cause dizziness, sleepiness and blurred vision, so drive only if you are alert. THALODA 50 MG TABLETS is not recommended for children. Avoid consuming alcohol with THALODA 50 MG TABLETS as it could lead to increased dizziness and sleepiness. THALODA 50 MG TABLETS, when taken with dexamethasone, increases the risk of deep vein thrombosis and pulmonary embolism. Stop taking THALODA 50 MG TABLETS and consult a doctor immediately if you have think you are pregnant, if you have irregular periods, missed a period, have any change in menstrual bleeding, or if you have had sex without using two forms of birth control.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Thaloda 50 Mg Tablets:
Taking carboplatin with Thaloda 50 Mg Tablets can increase the risk of blood clots.

How to manage the interaction:
Co-administration of carboplatin with Thaloda 50 Mg Tablets can possibly result in an interaction, but it can be taken if your doctor has advised it. However, If you experience chest pain, breathing difficulty, coughing up blood, and pain, redness, or swelling in an arm or leg, sudden loss of vision, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Thaloda 50 Mg Tablets:
Taking Thaloda 50 Mg Tablets together with daunorubicin may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking Thaloda 50 Mg Tablets and daunorubicin together can possibly result in an interaction, but it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Thaloda 50 Mg Tablets:
Taking Thaloda 50 Mg Tablets with temozolomide can increase the risk of blood clots.

How to manage the interaction:
Although taking temozolomide and Thaloda 50 Mg Tablets together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg. Do not stop using any medications without consulting doctor.
How does the drug interact with Thaloda 50 Mg Tablets:
Co-administration of Thaloda 50 Mg Tablets together with Mercaptopurine may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking Thaloda 50 Mg Tablets and mercaptopurine together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Thaloda 50 Mg Tablets:
Taking Thaloda 50 Mg Tablets together with paclitaxel may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking Thaloda 50 Mg Tablets and paclitaxel together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Thaloda 50 Mg Tablets:
Coadministration of Thaloda 50 Mg Tablets and hydrocortisone can increase the risk of blood clots.

How to manage the interaction:
Co-administration of Thaloda 50 Mg Tablets and hydrocortisone can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and pain, redness ,or swelling in an arm or leg, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Thaloda 50 Mg Tablets:
Taking Thaloda 50 Mg Tablets together with estradiol may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking estradiol and Thaloda 50 Mg Tablets together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Thaloda 50 Mg Tablets:
Taking Thaloda 50 Mg Tablets with Infliximab may increase the risk of infection.

How to manage the interaction:
Although taking Thaloda 50 Mg Tablets and infliximab together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Thaloda 50 Mg Tablets:
Using Thaloda 50 Mg Tablets together with anastrozole can increase the risk of dangerous blood clots.

How to manage the interaction:
Although taking Thaloda 50 Mg Tablets with Anastrozole together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience shortness of breath, difficulty breathing, chest pain, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg, contact a doctor immediately. Do not stop taking any medication without doctors advise.
How does the drug interact with Thaloda 50 Mg Tablets:
Taking Thaloda 50 Mg Tablets together with bevacizumab may increase the risk of blood clots.

How to manage the interaction:
Although taking Thaloda 50 Mg Tablets and bevacizumab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include food rich in iron, such as lean red meat, raisins, bell peppers, Brussel sprouts, and broccoli.
  • To prevent constipation, consume fibre rich foods such as whole grains, broccoli, dried fruits, nuts, beans, apples, oranges, and pears. 

Side Effects of THALODA 50 MG TABLETS

  • Constipation
  • Dizziness
  • Sleepiness
  • Tiredness
  • Tremor
  • Dysaesthesia (abnormal sensation)
  • Low blood cell count
  • Swelling of hands and feet
  • Nausea
  • Vomiting
  • Indigestion

Habit Forming

No

Therapeutic Class

ANTILEPROTICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

THALODA 50 MG TABLETS stops the development of cancer cells, stops the blood vessels growing in cancer, and stimulates the part of the immune system to attack the cancer cells. Thereby, THALODA 50 MG TABLETS helps treat multiple myeloma.

Do not stop taking THALODA 50 MG TABLETS on your own. You are advised to take THALODA 50 MG TABLETS for as long as your doctor has prescribed it for you, depending on your medical condition. Do not be reluctant to speak with your doctor if you experience any difficulty while taking THALODA 50 MG TABLETS.

Orthostatic hypotension could be a side-effect of THALODA 50 MG TABLETS. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better.

No, it is not safe to father a child while taking THALODA 50 MG TABLETS. Thalidomide is present in the semen of male patients taking THALODA 50 MG TABLETS; it could cause severe birth defects or death of the unborn baby. During sexual activity with females of reproductive potential, always use effective contraception such as latex or synthetic condom while taking THALODA 50 MG TABLETS and for at least 4weeks after discontinuing THALODA 50 MG TABLETS, even if you have undergone a successful vasectomy. Male patients taking THALODA 50 MG TABLETS must not donate semen.

Patients taking THALODA 50 MG TABLETS must not donate blood during the treatment with THALODA 50 MG TABLETS and for 4weeks after discontinuation of THALODA 50 MG TABLETS as the donated blood might be given to pregnant women whose foetus should not be exposed to thalidomide since it causes severe birth defects or death of the unborn baby.

People with multiple myeloma taking THALODA 50 MG TABLETS may have an increased risk for blood clots in veins, arteries, and lungs. The risk is higher if you take dexamethasone with THALODA 50 MG TABLETS for treating multiple myeloma. Consult your doctor immediately if you notice symptoms such as shortness of breath, chest pain, and swelling in the legs or arm.

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • DULOXETINE
  • ARIPIPRAZOLE
  • PROCHLORPERAZINE
  • LEVOFLOXACIN
  • TRAMADOL
  • BORTEZOMIB
  • ONDANSETRON
  • PHENOBARBITAL
  • SECOBARBITAL

Special Advise

  • Do not take THALODA 50 MG TABLETS if you are pregnant as it might cause severe birth defects or death of the unborn baby.
  • Male patients taking THALODA 50 MG TABLETS must not donate semen and should use effective contraception during sexual activity even though they have undergone vasectomy.
  • You must not donate blood while taking THALODA 50 MG TABLETS and for 4 weeks after discontinuing THALODA 50 MG TABLETS.
  • THALODA 50 MG TABLETS might increase the risk of blood clots, so consult a doctor if you notice any symptoms such as chest pain, shortness of breath, swelling of arm or leg.

Disease/Condition Glossary

Multiple myeloma: Multiple myeloma is a type of cancer that affects a type of white blood cells called plasma cells. These cells collect in the bone marrow and divide uncontrollably, leading to kidney and bone damage. Symptoms include bone pain, loss of appetite, fever, and frequent infections. Generally, multiple myeloma cannot be cured, but the signs and symptoms can be reduced greatly or disappear after a period of time.

Erythema Nodosum Leprosum (ENL): It is an immune-mediated inflammatory complication of leprosy. It is a painful disorder characterised by tender bumps under the skin, fever, arthritis, and fatigue. 

Have a query?

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking THALODA 50 MG TABLETS as it might cause increased sleepiness.

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Pregnancy

Unsafe

THALODA 50 MG TABLETS belongs to pregnancy category X. THALODA 50 MG TABLETS should not be taken during pregnancy as it causes severe birth defects or death to an unborn baby. Use highly effective contraception if you are a woman of child-bearing age. Inform your doctor if you are pregnant, think you are pregnant or planning for pregnancy.

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Breast Feeding

Unsafe

Avoid breastfeeding while taking THALODA 50 MG TABLETS as it is unknown if THALODA 50 MG TABLETS passes into breastmilk.

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Driving

Unsafe

THALODA 50 MG TABLETS may cause dizziness, sleepiness, and blurred vision. Do not drive or operate heavy machinery unless you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

THALODA 50 MG TABLETS is not recommended for children below 18 years as safety and effectiveness have not been established.

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