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Written By Divya L , PharmaD
Reviewed By Santoshini Reddy G , M Pharmacy

Thermodol Injection belongs to the group of analgesics (pain killers)

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Manufacturer/Marketer :

Akumentis Healthcare Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Thermodol Injection

Thermodol Injection belongs to the group of medicines called analgesic and antipyretic agents, primarily used to relieve mild to moderate pain and to treat fever. Pain is a symptom triggered by the nervous system, which causes uncomfortable sensations in the body. Fever occurs when the body's temperature goes above the average body temperature (98.6°F or 37°C).

Thermodol Injection contains 'Paracetamol,' which prevents the formation of chemical messengers called prostaglandins, which cause pain and swelling at the injury sites. This process reduces the mild to moderate pain and inflammation at the injured or damaged site. Thermodol Injection also affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thus, it reduces fever.

Your doctor will decide the dose and duration of Thermodol Injection based on the severity of your medical condition. Common side effects of Thermodol Injection include constipation, nausea, and vomiting. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Please tell your doctor if you are allergic to any of the components of Thermodol Injection. Let your doctor know if you use any other pain killers before starting this medicine. Inform your doctor if you have liver or kidney diseases, malnutrition, dehydration, and a history of alcoholism before starting Thermodol Injection. It is essential to let your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother. It is not recommended to consume alcohol while using Thermodol Injection.

Uses of Thermodol Injection

Pain and Fever.

Directions for Use

Thermodol Injection will be injected by a healthcare professional. Do not self-administer.

Medicinal Benefits

Thermodol Injection contains 'Paracetamol,' which is an analgesic (relieves pain) and an antipyretic (reduces fever). It prevents the formation of chemical messengers called prostaglandins, which cause pain and swelling at the injury sites. This process reduces the mild to moderate pain and inflammation at the injured or damaged site. Thermodol Injection also affects an area of the brain that regulates body temperature known as the hypothalamic heat-regulating centre. Thus, it reduces fever.

Storage

Keep out of sight and reach of children.
Side effects of Thermodol Injection
  • Tell your doctor about any pain or discomfort at the infusion site.
  • Apply a warm compress to reduce swelling and ease pain.
  • Switch infusion sites to avoid irritating the same spot.
  • Practice calming techniques like deep breathing, meditation, or yoga to manage pain and anxiety.

Drug Warnings

Let your doctor know if you use any prescription and non-prescription medications, including other vitamins, before starting Thermodol Injection. Notify your doctor if you have any intolerance or allergy to any of the components in Thermodol Injection. Inform your doctor if you have liver or kidney diseases, malnutrition, dehydration, and a history of alcoholism before starting Thermodol Injection. Please consult your doctor know if you are pregnant, planning to conceive or are a breastfeeding mother. Do not consume alcohol while being treated with Thermodol Injection.

Drug-Drug Interactions

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ParacetamolLomitapide
Severe
ParacetamolMipomersen
Severe

Drug-Drug Interactions

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ParacetamolLomitapide
Severe
How does the drug interact with Thermodol Injection:
Co-administration of Lomitapide and Thermodol Injection may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Thermodol Injection and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Thermodol Injection:
Co-administration of Mipomersen with Thermodol Injection may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Thermodol Injection and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Thermodol Injection:
Co-administration of Thermodol Injection may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Thermodol Injection, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Thermodol Injection:
Co-administration of Thermodol Injection and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Thermodol Injection and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
How does the drug interact with Thermodol Injection:
Co-administration of ketamine and Thermodol Injection may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Thermodol Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Thermodol Injection:
Co-administration of Teriflunomide with Thermodol Injection may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Thermodol Injection with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Thermodol Injection:
Co-administration of Thermodol Injection and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Thermodol Injection and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
How does the drug interact with Thermodol Injection:
Co-administration of Thermodol Injection and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Thermodol Injection and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Performing yoga may help in improving overall flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy; apply a cold or hot compress on the joints for 15-20minutes regularly.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Side Effects of Thermodol Injection

  • Constipation 
  • Nausea
  • Vomiting 

Habit Forming

No

Therapeutic Class

ANALGESIC AND ANTIPYRETIC AGENT

Author Details

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Drug-Diseases Interactions

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PARACETAMOL-1.0% W/VMental and behavioural disorders due to use of alcohol
Severe
PARACETAMOL-1.0% W/VHepatic failure, not elsewhere classified
Severe

Drug-Diseases Interactions

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PARACETAMOL-1.0% W/VMental and behavioural disorders due to use of alcohol
Severe
How does the disease interact with Thermodol Injection:
Chronic alcoholics may have a higher risk of hepatotoxicity when using Thermodol Injection. Patients using Thermodol Injection may cause severe liver damage, including acute liver failure that required a liver transplant and resulted in death.

How to manage the interaction:
Thermodol Injection should be used with caution in patients who consume three or more alcoholic drinks a day. Avoid alcohol consumption while taking Thermodol Injection. If you have nausea, vomiting, fever, rash, anorexia (eating disorder), over-tiredness, upper right stomach pain, dark urine, and jaundice, contact your doctor as these may be signs and symptoms of liver injury.
PARACETAMOL-1.0% W/VHepatic failure, not elsewhere classified
Severe
How does the disease interact with Thermodol Injection:
The liver predominantly converts Thermodol Injection to inactive forms. Patients with hepatic impairment may be more prone to toxicity because their minor metabolic pathways are more active.

How to manage the interaction:
Thermodol Injection should be used with caution in patients with kidney insufficiency. Also, it is recommended to avoid drinking alcohol while taking Thermodol Injection.

FAQs

Thermodol Injection works by blocking the effect of chemical messengers (prostaglandins), thereby reducing fever, pain, stiffness, swelling, and inflammation.

It is not advised to take Thermodol Injection on your own. You should use Thermodol Injection only if a healthcare professional prescribes it.

Thermodol Injection is to be cautiously used in case of any allergic reactions to other pain killers. Let your doctor know your medical history before starting Thermodol Injection.

Though Thermodol Injection is usually safe to use, it may very rarely cause serious skin reactions like generalized exanthematous pustulosis (AGEP), Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN). Please discontinue the usage of Thermodol Injection if you notice any skin rash and consult your doctor immediately.

Drug-Drug Interactions Checker List

  • PROBENECID
  • WARFARIN
  • ACENOCOUMAROL
  • SALICYLAMIDE

Disease/Condition Glossary

Pain: It is not a disease but a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body).

Fever: When the body's temperature goes above the average temperature of 98.6°F (37°C), it is called fever or pyrexia. It is considered as a response of the body's immune system to external factors.

Have a query?

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Thermodol Injection. Alcohol intake, along with Thermodol Injection may cause increased liver damage.

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Pregnancy

Caution

Please consult your doctor before taking Thermodol Injection if you are a pregnant.

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Breast Feeding

Caution

Thermodol Injection should be used during breastfeeding only when suggested by a doctor.

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Driving

Safe if prescribed

Thermodol Injection does not usually affect your ability to drive.

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Liver

Caution

Please consult your doctor since Thermodol Injection should be used with caution in patients with liver impairment/liver disease.

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Kidney

Caution

Please consult your doctor since Thermodol Injection should be used with caution in patients with kidney impairment/kidney disease.

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Children

Caution

Thermodol Injection should be given to children only when prescribed by a doctor

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