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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy

About THIAKLOR 12.5MG TABLET

THIAKLOR 12.5MG TABLET belongs to a group of medicines called thiazide-related diuretics (which increase the production of urine) and is primarily used to treat high blood pressure, heart failure and oedema (a build-up of fluid in the body). Hypertension or high blood pressure is a chronic condition in which the force exerted by the blood against the artery wall is high. The higher this blood pressure, the harder the heart has to pump. As a result, it leads to heart diseases, irregular heartbeat and other complications. Oedema may occur in case of high blood pressure where fluids of the body get trapped in the tissues of the hands, arms, feet, ankles and legs, leading to its swelling.

THIAKLOR 12.5MG TABLET works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

You can take THIAKLOR 12.5MG TABLET with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite or break it. Your doctor will advise you on how often you take your medicine based on your medical condition. In some cases, you may experience headaches, nausea or dizziness. Most of these side effects of THIAKLOR 12.5MG TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine on your own as it may cause a rise in blood pressure and can increase the risk of getting heart diseases and stroke. Inform your doctor if you are suffering from any kidney or liver, or heart disease. If you are pregnant or breastfeeding, please tell your doctor so that the dosage of THIAKLOR 12.5MG TABLET can be prescribed accordingly. Please tell your doctor if you are taking any other medicines or are allergic to this medicine. 

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Manufacturer/Marketer

Emcure Pharma Ltd (Renal Care)

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of THIAKLOR 12.5MG TABLET

High blood pressure, Heart failure, Oedema.

Medicinal Benefits

THIAKLOR 12.5MG TABLET works by increasing the amount of urine that is passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats oedema (swelling) associated with heart, liver, kidney or lung disease. This reduces the workload on the heart and makes the heart more efficient at pumping blood throughout the body. Thus, it helps lower high blood pressure, reducing the chances of heart attack or stroke. In addition, this relieves oedema and helps you carry out your daily activities more efficiently.

Side Effects of THIAKLOR 12.5MG TABLET

  • Headache
  • Dizziness
  • Nausea
  • Vomiting
  • Stomach cramping
  • Diarrhoea
  • Constipation
  • Loss of appetite

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

THIAKLOR 12.5MG TABLET should not be given to the people allergic to it, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, pregnant women or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart) and aortic stenosis (heart valve problem). THIAKLOR 12.5MG TABLET can pass into breast milk, but its effect on the baby is not known. So, it is better to tell your doctor if you are taking THIAKLOR 12.5MG TABLET and breastfeeding.

Therapeutic Class

CARDIOVASCULAR AGENTS

Drug-Drug Interactions

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chlorthalidoneCisapride
Critical
chlorthalidoneDroperidol
Severe

Drug-Drug Interactions

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chlorthalidoneCisapride
Critical
How does the drug interact with THIAKLOR 12.5MG TABLET:
Co-administration of THIAKLOR 12.5MG TABLET and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking THIAKLOR 12.5MG TABLET with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
chlorthalidoneDroperidol
Severe
How does the drug interact with THIAKLOR 12.5MG TABLET:
Taking Droperidol can make THIAKLOR 12.5MG TABLET less effective in lowering blood pressure.

How to manage the interaction:
Taking THIAKLOR 12.5MG TABLET with Droperidol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away. These symptoms include an irregular heart rhythm, severe or long-lasting diarrhea or vomiting, complications, sudden dizziness or lightheadedness, fainting, difficulty breathing, heart palpitations, weakness, feeling sleepy or confused, muscle pain, and feeling nauseous or vomiting. Do not stop using any medications without first talking to your doctor.
chlorthalidoneZiprasidone
Severe
How does the drug interact with THIAKLOR 12.5MG TABLET:
Co-administration of THIAKLOR 12.5MG TABLET with ziprasidone can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction, THIAKLOR 12.5MG TABLET can be taken with ziprasidone if prescribed by the doctor. but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
chlorthalidonePimozide
Severe
How does the drug interact with THIAKLOR 12.5MG TABLET:
Co-administration of THIAKLOR 12.5MG TABLET with pimozide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is an interaction, THIAKLOR 12.5MG TABLET can be taken with pimozide if prescribed by the doctor. Consult the prescriber if you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with pimozide. Also, let the doctor know if you experience signs of electrolyte disturbance, such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting. Do not discontinue any medications without consulting a doctor.
chlorthalidoneArsenic trioxide
Severe
How does the drug interact with THIAKLOR 12.5MG TABLET:
Taking THIAKLOR 12.5MG TABLET can make the body eliminate Arsenic trioxide faster, leading to lower levels in the blood and potentially reducing its effectiveness.

How to manage the interaction:
Co-administration of THIAKLOR 12.5MG TABLET with Arsenic trioxide can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: your heart beating irregularly, feeling dizzy or lightheaded, fainting, having a fast or pounding heartbeat, feeling weak or drowsy, being confused, experiencing muscle pain, or feeling nauseous or vomiting. Do not discontinue any medications without consulting a doctor.
chlorthalidoneTizanidine
Severe
How does the drug interact with THIAKLOR 12.5MG TABLET:
Co-administration of Tizanidine and THIAKLOR 12.5MG TABLET may show additive effects and increase the risk of low blood pressure.

How to manage the interaction:
Although there is an interaction, THIAKLOR 12.5MG TABLET can be taken with tizanidine if prescribed by the doctor. If you experience headache, dizziness, palpitations, or sweating, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
chlorthalidoneAminolevulinic acid
Severe
How does the drug interact with THIAKLOR 12.5MG TABLET:
Co-administration of Aminolevulinic acid and THIAKLOR 12.5MG TABLET may increase the risk of severe sunburn.

How to manage the interaction:
Taking THIAKLOR 12.5MG TABLET with Aminolevulinic acid together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice that your skin is very sensitive to sunlight or if you have a really bad sunburn, it's important to contact your doctor right away. Do not discontinue any medications without consulting a doctor.
chlorthalidoneLithium
Severe
How does the drug interact with THIAKLOR 12.5MG TABLET:
Co-administration of THIAKLOR 12.5MG TABLET together with lithium can increase the effects of lithium.

How to manage the interaction:
Although there is a interaction between THIAKLOR 12.5MG TABLET and lithium, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience diarrhea, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness. Do not discontinue any medications without consulting a doctor.
chlorthalidoneAmiodarone
Severe
How does the drug interact with THIAKLOR 12.5MG TABLET:
Coadministration of THIAKLOR 12.5MG TABLET with amiodarone may increase the risk of abnormal heart rhythms.

How to manage the interaction:
Although taking THIAKLOR 12.5MG TABLET with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor. Do not stop taking any medications without visiting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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CHLORTALIDONE-12.5MGAnuria and oliguria
Severe
CHLORTALIDONE-12.5MGAnuria and oliguria
Severe

Drug-Diseases Interactions

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CHLORTALIDONE-12.5MGAnuria and oliguria
Severe
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics should not be used in people who have anuria.

How to manage the interaction:
THIAKLOR 12.5MG TABLET is contraindicated in patients with anuria.
CHLORTALIDONE-12.5MGAnuria and oliguria
Severe
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics should not be used in people who have anuria.

How to manage the interaction:
THIAKLOR 12.5MG TABLET is contraindicated in patients with anuria.
CHLORTALIDONE-12.5MGOther disorders of fluid, electrolyte and acid-base balance
Severe
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics are usually associated with electrolyte loss, most notably potassium, but also sodium, chloride, bicarbonate, and magnesium. Other electrolytes, such as phosphate, bromide, and iodide, are normally lost in trace amounts. Potassium and magnesium deficiency can cause arrhythmias and cardiac arrest. Metabolic alkalosis and hyponatremia are two other electrolyte-related disorders that are seldom fatal.

How to manage the interaction:
Therapy with THIAKLOR 12.5MG TABLET should be administered cautiously in patients with or predisposed to fluid and electrolyte depletion. Fluid and electrolyte abnormalities should be corrected before initiating therapy, and blood pressure and serum electrolyte concentrations should be monitored periodically and maintained at normal ranges during therapy. Consult the doctor if you experience signs and symptoms of fluid or electrolyte imbalance, including dry mouth, thirst, weakness, lethargy, drowsiness, restlessness, muscle pains or cramps, muscular fatigue, hypotension, oliguria, tachycardia, arrhythmia, or gastrointestinal disturbances such as nausea and vomiting.
CHLORTALIDONE-12.5MGOther diseases of liver
Severe
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide-induced hypokalemic hypochloremic alkalosis is especially dangerous in patients with severe liver disease or cirrhosis. In individuals with already elevated amounts, blood ammonia levels may rise further. Electrolyte changes associated with diuretic usage have resulted in hepatic encephalopathy and mortality. Thiazide diuretic therapy should be used with caution in patients with poor hepatic function or progressive liver disease, and should be stopped immediately if indications of imminent hepatic coma occur (e.g., tremors, disorientation, and increasing jaundice).

How to manage the interaction:
Therapy with THIAKLOR 12.5MG TABLET should be administered cautiously in patients with impaired liver function or progressive liver disease, and discontinued promptly if signs of impending hepatic coma appear.
CHLORTALIDONE-12.5MGSystemic lupus erythematosus
Severe
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics have been reported to worsen or activate systemic lupus erythematosus. Chlorothiazide and hydrochlorothiazide have been linked to reported instances. Thiazide diuretics should be used with caution in individuals having a history or risk of SLE.

How to manage the interaction:
The use of THIAKLOR 12.5MG TABLET has been reported to possibly exacerbate or activate systemic lupus erythematosus (SLE). Therapy with thiazide diuretics should be administered cautiously in patients with a history or risk of SLE.
CHLORTALIDONE-12.5MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics may be ineffective when the glomerular filtration rate (GFR) is low (less than 25 mL/min) because they are not expected to be filtered into the renal tubule, where they work. Furthermore, thiazide diuretics lower GFR and may cause azotemia in patients with renal failure. Because most of these medicines are eliminated unaltered in the urine through glomerular filtration and active tubular secretion, cumulative effects may occur. Thiazide diuretic therapy should be used with caution and at lower doses in individuals with renal impairment. If renal function worsens over time, as shown by increased BUN or serum creatinine levels, thiazide medication should be interrupted or discontinued.

How to manage the interaction:
Therapy with THIAKLOR 12.5MG TABLET should be administered cautiously at reduced dosages in patients with kidney impairment.
CHLORTALIDONE-12.5MGAsthma
Moderate
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics should be administered with caution in individuals with a history of bronchial asthma because to the possibility of hypersensitive responses.

How to manage the interaction:
THIAKLOR 12.5MG TABLET should be used with caution in patients with history of bronchial asthma as sensitivity reactions may occur.
CHLORTALIDONE-12.5MGUnspecified diabetes mellitus
Moderate
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics can induce hyperglycemia and glycosuria in diabetics. They can also cause diabetes in pre-diabetic persons. These symptoms are normally reversible if the medicines are stopped. Thiazide diuretic therapy should be used with caution in individuals with diabetes, glucose intolerance, or a propensity to hyperglycemia. Diabetes mellitus patients should be regularly watched during thiazide medication, and their antidiabetic regimen should be changed accordingly.

How to manage the interaction:
THIAKLOR 12.5MG TABLET may cause high blood sugar levels and glycosuria (glucose in the urine) in patients with diabetes. Therapy with THIAKLOR 12.5MG TABLET should be administered cautiously in patients with diabetes mellitus, glucose intolerance, or a predisposition to high blood sugar levels. Patients with diabetes mellitus should be monitored more closely during therapy.
CHLORTALIDONE-12.5MGDisorders of lipoprotein metabolism and other lipidaemias
Moderate
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics may raise blood triglyceride and cholesterol levels, particularly LDL and VLDL. It is uncertain if these effects are dose-related and persist throughout chronic treatment. Patients with pre-existing hyperlipidemia may require stricter monitoring during thiazide medication, and their lipid-lowering regimen may need to be adjusted accordingly.

How to manage the interaction:
THIAKLOR 12.5MG TABLET may increase serum triglyceride and cholesterol levels, primarily low-density lipoprotein and very low-density lipoprotein. Patients with preexisting hyperlipidemia may require closer monitoring during thiazide therapy.
CHLORTALIDONE-12.5MGHyperparathyroidism and other disorders of parathyroid gland
Moderate
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics reduce urinary calcium excretion when used on a long-term basis. Prolonged treatment has been associated with pathologic alterations in the parathyroid gland, including hypercalcemia and hypophosphatemia. However, typical hyperparathyroidism consequences such as renal lithiasis, bone resorption, and peptic ulcers have not been observed. Clinicians should be aware of these side effects while prescribing or providing thiazide medication to hyperparathyroid patients. These medications should be stopped before doing parathyroid function testing.

How to manage the interaction:
Caution is advised while using THIAKLOR 12.5MG TABLET in patients with hyperparathyroidism.
CHLORTALIDONE-12.5MGDisorders of purine and pyrimidine metabolism
Moderate
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics slow the excretion of uric acid. Except in patients with a history of gout or chronic renal failure, hyperuricemia is typically asymptomatic and seldom progresses to clinical gout. Thiazide diuretic therapy should be used with caution in such individuals.

How to manage the interaction:
THIAKLOR 12.5MG TABLET may decrease the rate of uric acid excretion. Therapy should be administered cautiously in such patients.
CHLORTALIDONE-12.5MGAbnormal results of function studies
Moderate
How does the disease interact with THIAKLOR 12.5MG TABLET:
Thiazide diuretics may lower serum PBI (protein-bound iodine) levels without causing thyroid problems. When prescribing or providing thiazide medication to patients with thyroid problems, clinicians should be aware of this consequence.

How to manage the interaction:
Thiazide diuretics may decrease serum PBI (protein-bound iodine) levels without associated thyroid disturbance. Inform the prescriber if you have thyroid disorders.

Drug-Drug Interactions Checker List

  • BENAZEPRIL
  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ATORVASTATIN
  • SIMVASTATIN
  • DILTIAZEM
  • VERAPAMIL
  • LISINOPRIL
  • SILDENAFIL
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • CYCLOSPORINE
  • IBUPROFEN
  • ASPIRIN

Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Opt for a diet rich in whole grains, fruits, veggies and low-fat dairy products.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol then only one serving for women and two servings for men is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation then immediately contact your doctor.
  • Try to include heart-healthy omega 3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil can help in lowering your elevated blood pressure.

Habit Forming

No

Special Advise

  •  
  • THIAKLOR 12.5MG TABLET is generally advised to treat high blood pressure and other heart conditions.
  • THIAKLOR 12.5MG TABLET should be taken at the same time every day for its maximum effects to be seen and for increased compliance.
  • Consumption of THIAKLOR 12.5MG TABLET may cause dizziness. Avoid activities like driving while on this medication.
  • A sudden drop in blood pressure may be seen while on this medication which might lead to dizziness. Changing your posture at a slower rate might help counter this.
  • THIAKLOR 12.5MG TABLET may alter your sugar and lipid levels when taken for the long term. Thus, regular monitoring of blood sugar and lipid levels is recommended. Consult your doctor if this or other side effects cause trouble or are persistent.
  •  

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is the pressure when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure is around 120/80 mm of Hg.

THIAKLOR 12.5MG TABLET Substitute

Substitutes safety advice
  • Chlornol-12.5mg Tablet 10's

    by AYUR

    4.05per tablet
  • Chlotado 12.5 Tablet 10's

    5.31per tablet
  • CT-Don 12.5 mg Tablet 10's

    10.44per tablet
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