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  3. Tigibru 50 Injection

Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma

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Composition :

TIGECYCLINE-50MG

Manufacturer/Marketer :

Brawn Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Tigibru 50 Injection

Tigibru 50 Injection belongs to the class of 'antibiotics,' primarily used to treat bacterial infections like abdominal infections, community-acquired pneumonia (lung infection), and complicated skin and skin structure infections. Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Tigibru 50 Injection does not work for viral infections, such as common cold and flu.

Tigibru 50 Injection contains 'Tigecycline' that belongs to the class of 'glycylcyclines'. It works by preventing the synthesis of bacterial proteins, which are the primary cursors for carrying out bacteria's vital functions. This process further inhibits bacterial growth. 

Tigibru 50 Injection will be administered by a healthcare professional; do not self-administer it. Your doctor will decide the dose and duration of Tigibru 50 Injection based on your medical condition. Like all medicines, Tigibru 50 Injection also causes side effects, although not everybody gets them. Common side effects of Tigibru 50 Injection include nausea, vomiting, diarrhoea, headache, and abnormal liver function tests. If any of these effects persist or worsen, seek medical advice promptly.

Brief your medical history to the doctor if you are allergic to Tigibru 50 Injection or any of its components. Let your doctor know if you have any kidney or liver diseases, colitis (inflammation of the inner lining of the colon), and pancreatitis (inflammation of the pancreas). Tigibru 50 Injection is not recommended during pregnancy due to its harmful effects on the baby. It is advised to consult your doctor if you are breastfeeding before taking Tigibru 50 Injection. Tigibru 50 Injection can make you feel dizzy; hence drive or operate machinery only when you are alert. Tigibru 50 Injection is not recommended in children below eight years of age. 

Uses of Tigibru 50 Injection

Bacterial infections.

Directions for Use

Tigibru 50 Injection will be administered by a healthcare professional; do not self-administer it.

Medicinal Benefits

Tigibru 50 Injection contains 'Tigecycline,' a broad-spectrum glycylcycline antibiotic that treats bacterial infections, such as abdominal infections, community-acquired pneumonia (lung infection), and complicated skin and skin structure infections. It works by preventing the synthesis of bacterial proteins, which are the primary cursors for carrying out bacteria's vital functions. Tigecycline is bacteriostatic and inhibits bacterial reproduction.

Storage

Keep out of sight and reach of children.

Drug Warnings

Let your doctor know if you have any kidney or liver diseases, colitis (inflammation of the inner lining of the colon), and pancreatitis. Clostridium difficile-associated diarrhoea (CDAD) is reported during usage of antibiotics like Tigibru 50 Injection. Therefore, please undergo an examination to rule out the chances of CDAD if you experience diarrhoea following Tigecycline therapy. Let your doctor know if you are undergoing any vaccinations with live bacterial vaccines (like typhoid vaccine) since Tigibru 50 Injection may affect vaccines' activity. Tigibru 50 Injection may induce photosensitivity and makes your skin more sensitive to the sun; hence apply sunscreen when you step out. Tigibru 50 Injection is not recommended during pregnancy due to its harmful effects on the baby. Please seek medical advice if you are breastfeeding before taking Tigibru 50 Injection. Tigibru 50 Injection causes dizziness; hence drive or operate machinery only when you are alert. Tigibru 50 Injection is not recommended in children below eight years of age. 

Diet & Lifestyle Advise

  • Include more fibre enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains like whole-grain bread, brown rice should be included in your diet. 
  • Eating grapefruit during antibiotics treatment can prevent the body from utilizing Tigibru 50 Injection properly. So, avoid intake of grapefruit or grapefruit juice with the antibiotic. 
  • Avoid taking too much calcium, iron-enriched foods and drinks as it might affect the working of Tigibru 50 Injection. 
  • Avoid intake of alcoholic beverages with Tigibru 50 Injection as it can make you dehydrated and affect your sleep. This can make it more challenging for your body to aid the Tigibru 50 Injection in fighting off infections.
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Do not walk barefoot at places like gym showers to prevent bacterial infections. 

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Author Details

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FAQs

Tigibru 50 Injection contains Tigecycline, a broad-spectrum antibiotic that treats various bacterial infections. It works by inhibiting bacterial protein synthesis, which further inhibits bacterial growth.

Tigibru 50 Injection can affect live vaccines like typhoid vaccine and decrease their effectiveness. Please consult a doctor before you start Tigibru 50 Injection if you are undergoing any vaccinations.

Tigibru 50 Injection can make your skin more sensitive to the harmful effects of sunlight. Hence it is advised to use sunscreen and wear protective clothing while using Tigibru 50 Injection. It is also recommended to avoid tanning booths and sunlamps.

Diarrhoea can be a side-effect of Tigibru 50 Injection. Drink enough fluids and eat fibre rich food if you experience diarrhoea. If you find blood in stools (tarry stools) or experience excess diarrhoea, consult your doctor. Do not take anti-diarrhoeal medicine on your own.

Drug-Drug Interactions Checker List

  • WARFARIN

Special Advise

  • Inform your doctor and laboratory staff in advance that you take Tigibru 50 Injection if you are undergoing any medical examinations. Tigibru 50 Injection can cause abnormal liver function test results.
  • Renal, liver function and blood tests are advised during prolonged therapy to rule out any toxicity caused due to overdose of Tigibru 50 Injection. 
  • Clostridium difficile associated diarrhoea (CDAD) is reported during the usage of antibiotics like Tigecycline. Please see your doctor if you experience prolonged diarrhoea.

Disease/Condition Glossary

Bacterial infection occurs when harmful bacteria grow in the body and causes illness. It can infect any part of the body and multiply very quickly. Bacteria occur in three basic shapes: spherical, rod and spiral-shaped. Bacteria may be gram-positive (have thick cell wall) or gram-negative (do not have a cell wall). Some common symptoms of a bacterial infection include cough, fever and tiredness. 

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