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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About TOBAREN D DROPS 5ML

TOBAREN D DROPS 5ML is a combination of one antibiotic and one corticosteroid used to treat bacterial eye and ear infections. It is used to treat eye infections such as conjunctivitis (infection of the outer white membrane of the eyeball), corneal ulcers (ulcer that occurs in the transplant membrane of the eye called the cornea), acute bacterial otitis media (an infection of the middle ear), and otitis externa (an infection in the ear canal). Eye infections are contagious and can pass from one to another. Signs and symptoms include pink or red-toned eyes, itching in areas of eyes, teary eyes, thick discharge around eyes/ears, ear discomfort, etc. 

TOBAREN D DROPS 5ML is a combination medicine that contains Tobramycin and Dexamethasone. Tobramycin is an aminoglycoside antibiotic which inhibits the growth of bacteria by interfering with protein synthesis and leads to cell death. Dexamethasone is a corticosteroid medicine that reduces swelling and redness by preventing infection-fighting white blood cells (WBCs). 

TOBAREN D DROPS 5ML is an external preparation and should be administered as advised by your doctor. TOBAREN D DROPS 5ML may cause certain common side effects, including (when used as eye drops) redness, itching, swelling, burning sensation, tearing, and temporary blurred vision (when used as ear drops), including ear pain and discomfort, discharge from ears, etc. Most of these side effects do not require medical attention and gradually subside over a time span. However, if the side effects persist for an extended period of time, consult your doctor. 

TOBAREN D DROPS 5ML should be avoided if you are allergic to it, other aminoglycoside antibiotics or any other ingredients present in it. Inform your doctor if you are on any topical nonsteroidal anti-inflammatory drugs (NSAIDs), as TOBAREN D DROPS 5ML combined with topical NSAIDs may cause your eye wound to heal more slowly. Avoid wearing contact lenses during the treatment of ocular infection or inflammation, as it can worsen the condition. Tell your doctor about all your current medications and medical history before using TOBAREN D DROPS 5ML. Inform your doctor if you have any vision or hearing problems after using this medication. Tell your doctor if you are pregnant or breastfeeding. TOBAREN D DROPS 5ML is not recommended for use in children below 2 years of age. 

rxMedicinePrescription drug

Whats That

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Non returnable*
COD available

Online payment accepted

Consume Type

EYE/EAR

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of TOBAREN D DROPS 5ML

Bacterial eye infectionsBacterial ear infections

Medicinal Benefits

TOBAREN D DROPS 5ML is a combination medicine that contains Tobramycin (antibiotics) and Dexamethasone (corticosteroids). Tobramycin works by inhibiting the growth of bacteria. Dexamethasone blocks the chemical messenger in the brain responsible for causing inflammation (redness, itching, and swelling). As a result, it lowers inflammation, which could worsen the condition. TOBAREN D DROPS 5ML is used to prevent and treat inflammation and prevent possible bacterial infection of the eye after cataract surgery in adults and children above two years of age. 

Side Effects of TOBAREN D DROPS 5ML

  • Eye redness
  • Burning sensation
  • Ear discomfort
  • Discharge from the ear
  • Ear pain
  • Dry eyes
  • Ringing sound 

Directions for Use

Eye drops: Wash your hands thoroughly with water before and after use. Tilt your head and pull down the lower eyelid to create a small sac. Squeeze the prescribed amount of dose into the sac using the dropper. Close your eyes for about 2 to 3 minutes. Wipe any excess liquid with a tissue. Do not wipe or rinse the dropper tip after use. Place the dropper back on the bottle and tighten the cap. Ear drops: Wash your hands thoroughly with water before and after use. Tilt your head towards the side, take the prescribed dose with the dropper, and squeeze the drops in the ear.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

  • It is for external use only. If you are allergic to TOBAREN D DROPS 5ML or any other medicines, please tell your doctor. Consult your doctor before using TOBAREN D DROPS 5ML if you are pregnant or breastfeeding. 
  • TOBAREN D DROPS 5ML is not recommended for children below 2 years of age. 
  • You are advised to remove soft contact lenses before using TOBAREN D DROPS 5ML as it contains a preservative that may cause eye irritation and discolouration of soft contact lenses. You can reinsert contact lenses after 15 minutes of using TOBAREN D DROPS 5ML. 
  • Do not use the topical non-steroidal inflammatory drug while using TOBAREN D DROPS 5ML. TOBAREN D DROPS 5ML contains dexamethasone; if you use a topical non-steroidal inflammatory drug and dexamethasone together, it may delay the healing of your eye wound. 
  • If you have diabetes, please consult your doctor before using TOBAREN D DROPS 5ML. The risk of intraocular pressure (glaucoma) and cataract formation is increased in diabetic patients. 
  • TOBAREN D DROPS 5ML may cause temporary vision problems (blurred vision), so be cautious while driving and operating machinery. 

Therapeutic Class

ANTIBACTERIAL AND CORTICOSTEROID

Drug-Drug Interactions

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TobramycinCidofovir
Critical
DexamethasoneRilpivirine
Critical

Drug-Drug Interactions

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TobramycinCidofovir
Critical
How does the drug interact with TOBAREN D DROPS 5ML:
Coadministration of cidofovir with TOBAREN D DROPS 5ML can cause kidney problems.

How to manage the interaction:
Taking TOBAREN D DROPS 5ML with Cidofovir is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
DexamethasoneRilpivirine
Critical
How does the drug interact with TOBAREN D DROPS 5ML:
When Rilpivirine is taken with TOBAREN D DROPS 5ML, may significantly reduce the blood levels of Rilpivirine.

How to manage the interaction:
Co-administration of Rilpivirine and TOBAREN D DROPS 5ML can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
DexamethasoneRanolazine
Critical
How does the drug interact with TOBAREN D DROPS 5ML:
When TOBAREN D DROPS 5ML is taken with Ranolazine, may significantly reduce the blood levels of Ranolazine.

How to manage the interaction:
Co-administration of Ranolazine and TOBAREN D DROPS 5ML can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
DexamethasoneDesmopressin
Critical
How does the drug interact with TOBAREN D DROPS 5ML:
Co-administration of Desmopressin with TOBAREN D DROPS 5ML may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
Co-administration of TOBAREN D DROPS 5ML and Desmopressin can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like confusion, hallucination, seizure, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DexamethasoneRegorafenib
Critical
How does the drug interact with TOBAREN D DROPS 5ML:
When Regorafenib is taken with TOBAREN D DROPS 5ML, may significantly reduce the blood levels of Regorafenib.

How to manage the interaction:
Co-administration of Regorafenib and TOBAREN D DROPS 5ML can lead to an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor's advice.
TobramycinAtracurium
Severe
How does the drug interact with TOBAREN D DROPS 5ML:
Using Atracurium with TOBAREN D DROPS 5ML can increase the risk of respiratory depression (breathing disorder).

How to manage the interaction:
Although there is a interaction between TOBAREN D DROPS 5ML and Atracurium, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to your doctor.
TobramycinTacrolimus
Severe
How does the drug interact with TOBAREN D DROPS 5ML:
Taking tacrolimus with TOBAREN D DROPS 5ML may increase risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and TOBAREN D DROPS 5ML together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.
TobramycinBumetanide
Severe
How does the drug interact with TOBAREN D DROPS 5ML:
When TOBAREN D DROPS 5ML is taken with Bumetanide, the amount of TOBAREN D DROPS 5ML in the blood can go up.

How to manage the interaction:
Although there is a possible interaction between TOBAREN D DROPS 5ML and Bumetanide, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
TobramycinTenofovir disoproxil
Severe
How does the drug interact with TOBAREN D DROPS 5ML:
Coadministration of TOBAREN D DROPS 5ML with Tenofovir disoproxil can increase the risk of kidney problems.

How to manage the interaction:
Taking Tenofovir disoproxil with TOBAREN D DROPS 5ML together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TobramycinPolymyxin b
Severe
How does the drug interact with TOBAREN D DROPS 5ML:
Taking TOBAREN D DROPS 5ML with Polymyxin B can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between TOBAREN D DROPS 5ML and Polymyxin b, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • VANCOMYCIN
  • GENTAMICIN
  • STREPTOMYCIN
  • DICLOFENAC
  • RITONAVIR
  • ITRACONAZOLE
  • PIOGLITAZONE
  • VORICONAZOLE
  • METFORMIN
  • ATAZANAVIR
  • BOCEPREVIR

Diet & Lifestyle Advise

  • Sleep for at least 6-8 hours to rejuvenate your eyes naturally.
  • Wash your eyes with clean water at least 2-3 times a day
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Placing cooled tea bags on your eyes while they are closed can be a way to relax and unwind.
  • Avoid pricking your ears with cotton buds or fingers as it can scratch the skin and allows germs which result in infection.
  • The ear infection can also occur due to improper cleaning of ears after bathing or swimming. Hence, cleaning your ears thoroughly with a clean and dry cloth is advised.

Habit Forming

No

Special Advise

  • Do not take TOBAREN D DROPS 5ML on your own, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections.
  • Using TOBAREN D DROPS 5ML for prolonged may result in a new fungal eye infection (secondary infection). Do not use TOBAREN D DROPS 5ML for longer than prescribed.
  • TOBAREN D DROPS 5ML should not be administered directly into the eye's anterior chamber.

Disease/Condition Glossary

Bacterial eye infection: Bacterial eye infection occurs when pathogenic bacteria infiltrate any part of the eye, including the eyeball, conjunctiva, and cornea. Conjunctivitis, keratitis, and other bacterial eye infections are common. The inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid is known as conjunctivitis (pink eye). It is a highly contagious infection spread through eye secretions. Redness, itchiness, and discharge or crusting around the eye are all symptoms. Keratitis is an inflammation of the cornea caused by contact lens use, injury, diabetes, or surgery.

Bacterial ear infection: Bacterial ear infection occurs when pathogenic bacteria infiltrate any part of the ear, including the eardrum, middle ear, and ear canal. Acute otitis media and otitis externa are two common bacterial ear infections. Acute bacterial otitis media is a middle ear infection that occurs behind the eardrum. It is most prevalent in children. Otitis externa (Swimmer's ear) is an infection of the ear canal, which connects to the eardrum. It is primarily caused by frequent pricking of the ear with cotton buds or inserting fingers into the ear, which results in ear infections.

TOBAREN D DROPS 5ML Substitute

Substitutes safety advice
  • NEBRACIN DM EYE DROPS 10ML

    by AYUR

    2.21per tablet
  • TOBAREN D EYE DROPS 10ML

    1.38per tablet
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