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  3. Tobavue 0.3%W/W Eye Oint 5G

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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

TOBRAMYCIN-0.3%W/W

Manufacturer/Marketer :

Elite Pharmaceuticals, Inc

Consume Type :

OPHTHALMIC

Return Policy :

Not Returnable

Expires on or after :

About Tobavue 0.3%W/W Eye Oint 5G

Tobavue 0.3%W/W Eye Oint 5G is an aminoglycoside antibiotic used to treat bacterial infections. It is mostly used to treat eye infections such as conjunctivitis. Besides this, it is also useful in the treatment of various bacterial infections of the brain and spinal cord (meningitis), stomach or intestinesbladder or kidney (urinary tract infection), lungs (pneumonia), and also used for infections of the bone, skin or soft tissue including burns. A bacterial infection is a condition in which bacteria grows in the body and cause infection. It can target any body part and multiply very quickly. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick.

Tobavue 0.3%W/W Eye Oint 5G contains tobramycin. It inhibits bacteria growth by interfering with protein synthesis. It binds to the proteins in the bacteria, disrupting the cell membrane, and eventually leading to cell death. It is active against various gram-negative bacteria and gram-positive bacteria (Staphylococcus aureus). It will not work for other types of infections such as viral, fungal, or parasitic infections.

It is available in the form of drops, ointment, injection, and inhalation. Tobavue 0.3%W/W Eye Oint 5G can cause some common side-effects (when eye drops are used) including redness, itching, swelling, burning sensation, tearing, and temporary blurred vision (with ointment use). Long term use of eye drops may cause a fungal eye infection. So, take this medicine for a duration prescribed by your doctor. When given as an injection, you may experience fever, rash, pain at the injection site, confusion, headache, and diarrhoea. Some patients may also experience serious side-effects such as hearing problems, muscle twitching, and convulsions that may require medical attention.

Inform your doctor if you are allergic to Tobavue 0.3%W/W Eye Oint 5G, other aminoglycoside antibiotics, or any other ingredients present in it. Inform your doctor if you are using other antibiotics, antifungal medication, antiviral drugs, diuretics, general anaesthetics, anti-cancer medicine, immune suppressant, and medications used to treat muscle weakness. Tell your doctor if you have myasthenia gravis (muscle disorders), Parkinson’s disease (a brain disorder), and kidney problems. Inform your doctor if you have any vision problems after using this medication. Tell your doctor if you are pregnant or breastfeeding.

Uses of Tobavue 0.3%W/W Eye Oint 5G

Bacterial infections

Directions for Use

Eye drops: Wash your hands thoroughly with water before and after use. Tilt your head back and pull down the lower eyelid to create a small sac. Take the prescribed amount of dose with the dropper and squeeze out a drop. Close your eyes for about 2 to 3 minutes. Wipe any excess liquid with a tissue. Do not wipe or rinse the dropper tip after use. Place the dropper back on the bottle and tighten the cap. Ointment: Eye ointment is also used similarly. Create a pocket pulling the lower eyelid while tilting your head back. Then, squeeze out a prescribed amount of ointment and close your eyes. You may experience blurred vision for some time after opening the eyes. So, rest for a while before doing anything. Injections: Injections are given using a syringe. Do not self-administer. Injections are given only by a healthcare professional. The prescribed dose is taken and injected into a muscle or vein. Infusions are given in the form of a drip into the vein by a healthcare professional. Inhalation: Inhalations are used by inhaling the medicine with the use of a nebulizer or inhaler. Do not mix or dilute the medicine unless advised by your doctor. Do not swallow it by mouth. Note: In case of drops/ointment, do not touch the tip of the dropper or ointment tube as it may contaminate the contents. Do not place the tip directly into the eye while instilling drops or ointment. If the dropper touches the eye, immediately squeeze two to three drops onto the tissue and wipe the dropper’s tip with saltwater.

Medicinal Benefits

Tobavue 0.3%W/W Eye Oint 5G belongs to a class of drugs called aminoglycoside antibiotics. It works by stopping the growth of bacteria. It reduces the infection by inhibiting bacterial growth. It irreversibly binds to a site on the bacterial ribosomes (ribosomes are responsible for protein synthesis), inhibiting protein formation. Proteins are essential for bacterial growth. So, if bacteria cannot make proteins, it will eventually die.

Storage

Ophthalmic solution: Store at 2°-25°C (36°-77°F), Injection: Store at 2-8°C (36-46°F)
Side effects of Tobavue 0.3%W/W Eye Oint 5G

Drug Warnings

Inform your doctor if you are allergic to Tobavue 0.3%W/W Eye Oint 5G, other aminoglycoside antibiotics, or any other ingredients present in it. Inform your doctor if you are using any prescription, nonprescription medications, nutritional supplements, or herbal products. Inform your doctor if you are using other antibiotics, antifungal medication, diuretics, general anaesthetics, chemotherapeutic agents, immune suppressants, and medications used to treat muscle weakness. Inform your doctor if you have any history of myasthenia gravis, Parkinson’s diseases, kidney problems, and eye problems. Inform your doctor if you have any vision problems after using this medication. Do not drive or operate heavy machinery until your vision stabilizes. Tell your doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tobavue 0.3%W/W Eye Oint 5G:
Coadministration of cidofovir with Tobavue 0.3%W/W Eye Oint 5G can cause kidney problems.

How to manage the interaction:
Taking Tobavue 0.3%W/W Eye Oint 5G with Cidofovir is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
How does the drug interact with Tobavue 0.3%W/W Eye Oint 5G:
Co-administration of Tobavue 0.3%W/W Eye Oint 5G with torasemide increases the risk of toxicity.

How to manage the interaction:
Although taking Tobavue 0.3%W/W Eye Oint 5G and torasemide together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms such as blurred vision, dry mouth, dry skin, frequent urination, nausea, and stomach pain, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tobavue 0.3%W/W Eye Oint 5G:
Coadministration of Tobavue 0.3%W/W Eye Oint 5G with Sirolimus can cause an increased risk or severity of kidney problems.

How to manage the interaction:
Although taking Sirolimus and Tobavue 0.3%W/W Eye Oint 5G together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Tobavue 0.3%W/W Eye Oint 5G:
Taking magnesium sulfate with Tobavue 0.3%W/W Eye Oint 5G can increase the risk of muscle weakness.

How to manage the interaction:
Although taking Magnesium sulfate and Tobavue 0.3%W/W Eye Oint 5G together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, if you experience symptoms such as muscle weakness and breathing difficulties consult your doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobavue 0.3%W/W Eye Oint 5G:
Using Atracurium with Tobavue 0.3%W/W Eye Oint 5G can increase the risk of respiratory depression (breathing disorder).

How to manage the interaction:
Although there is a interaction between Tobavue 0.3%W/W Eye Oint 5G and Atracurium, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to your doctor.
How does the drug interact with Tobavue 0.3%W/W Eye Oint 5G:
Taking deferasirox with Tobavue 0.3%W/W Eye Oint 5G may increase the risk of kidney problems.

How to manage the interaction:
Taking Tobavue 0.3%W/W Eye Oint 5G with Deferasirox together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Tobavue 0.3%W/W Eye Oint 5G:
Using Botulinum toxin and Tobavue 0.3%W/W Eye Oint 5G together may increase the risk of side effects.

How to manage the interaction:
Although taking Botulinum toxin and Tobavue 0.3%W/W Eye Oint 5G can cause an interaction, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience excessive muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tobavue 0.3%W/W Eye Oint 5G:
Using Vecuronium with Tobavue 0.3%W/W Eye Oint 5G can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Co-administration of Tobavue 0.3%W/W Eye Oint 5G with Vecuronium can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tobavue 0.3%W/W Eye Oint 5G:
Using Tobavue 0.3%W/W Eye Oint 5G together with everolimus can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Everolimus and Tobavue 0.3%W/W Eye Oint 5G, you can take these medicines together if prescribed by a doctor. However, if you experience sudden weight gain, feeling out of breath, or having kidney problems. If you experience nausea, vomiting, loss of appetite, weight loss, swelling, muscle cramps, weakness, dizziness, confusion, or an irregular heartbeat contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobavue 0.3%W/W Eye Oint 5G:
Takin human immunoglobulin with Tobavue 0.3%W/W Eye Oint 5G may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Tobavue 0.3%W/W Eye Oint 5G together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Sleep for at least six to eight hours to rejuvenate your eyes in a natural way.
  • Wash your eyes with clean water at least two to three times a day
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Keep your ear clean and dry.

Side Effects of Tobavue 0.3%W/W Eye Oint 5G

Tobavue 0.3%W/W Eye Oint 5G may show side-effects such as redness, itching, tearing, or swelling in the eye after the application of eye drops. These side-effects usually go away after a short time. With the injection, you may experience side-effects such as fever, rash, pain at the injection site, itching, fatigue, drowsiness, weakness, headache, confusion, and diarrhoea. Other side-effects of Tobavue 0.3%W/W Eye Oint 5G are hearing problems, dizziness, ringing in the ears, convulsions, and muscle twitching. These side-effects are serious, and you may require medical attention right away.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Tobavue 0.3%W/W Eye Oint 5G is mostly used for the treatment of eye infections. It is not recommended for the treatment of ear infections. However, it should be used for any indication only when prescribed by a doctor.

Tobavue 0.3%W/W Eye Oint 5G may improve within 2 to 3 days of administration. However, recovery depends on different factors such as age, the severity of the infection, and comorbidities.

It is recommended to use Tobavue 0.3%W/W Eye Oint 5G in children only with a doctor's advice.

Do not take any medications without consulting a doctor if you are allergic to penicillin.

Tobavue 0.3%W/W Eye Oint 5G injection can cause hearing loss, especially in elderly people. It may be permanent sometimes. So, contact your doctor immediately if you have vertigo, dizziness, or tinnitus (ringing in the ears).

Tobavue 0.3%W/W Eye Oint 5G contains tobramycin which is an aminoglycoside antibiotic. It acts by inhibiting bacteria's growth. It binds to the proteins in the bacteria, disrupting the cell functions, and eventually leading to bacterial death.

Before using Tobavue 0.3%W/W Eye Oint 5G, you must inform your doctor if you have any allergy to Tobavue 0.3%W/W Eye Oint 5G or any antibiotics or if you are taking any other medicines.

Drug-Drug Interactions Checker List

  • VANCOMYCIN
  • KANAMYCIN
  • GENTAMICIN
  • STREPTOMYCIN
  • FUROSEMIDE
  • NEOSTIGMINE
  • PYRIDOSTIGMINE
  • CYCLOSPORINE
  • AMPHOTERICIN B
  • CISPLATIN
  • CEPHALOTHIN
  • ETHACRYNIC ACID

Special Advise

Tobavue 0.3%W/W Eye Oint 5G may alter liver and kidney function, and blood cells count. So, laboratory tests may be performed to monitor these levels. Your doctor may also check for vision and hearing problems. 

Disease/Condition Glossary

Conjunctivitis: Conjunctivitis is an eye condition caused by infection or allergies.

Meningitis: Meningitis is an infection of the protective membranes that surround the brain and spinal cord (meninges).

Pneumonia: Pneumonia is swelling (inflammation) of the tissue in one or both lungs. It's usually caused by a bacterial infection. It can also be caused by a virus, such as a coronavirus (COVID-19).

Have a query?

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Alcohol

Unsafe

Tobavue 0.3%W/W Eye Oint 5G may increase the risk of drowsiness if alcohol is taken.

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Pregnancy

Caution

Tobavue 0.3%W/W Eye Oint 5G should be used with caution in pregnant women.

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Breast Feeding

Caution

Tobavue 0.3%W/W Eye Oint 5G should be used with caution in breastfeeding mothers.

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Driving

Caution

Tobavue 0.3%W/W Eye Oint 5G may cause drowsiness. So, it is recommended to avoid driving or operating heavy machinery after taking this medication.

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Liver

Safe if prescribed

Tobavue 0.3%W/W Eye Oint 5G is safe to use in patients with liver disease only when prescribed by a doctor.

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Kidney

Caution

Tobavue 0.3%W/W Eye Oint 5G should be used with caution in renal problems. Dose adjustments may be necessary.

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Children

Caution

Tobavue 0.3%W/W Eye Oint 5G should be used in children when prescribed by a child specialist only.

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