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  3. TOBRANEG 80MG INJECTION

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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

TOBRAMYCIN-80MG

Manufacturer/Marketer :

Elder Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About TOBRANEG 80MG INJECTION

TOBRANEG 80MG INJECTION is an aminoglycoside antibiotic used to treat bacterial infections. It is mostly used to treat eye infections such as conjunctivitis. Besides this, it is also useful in the treatment of various bacterial infections of the brain and spinal cord (meningitis), stomach or intestinesbladder or kidney (urinary tract infection), lungs (pneumonia), and also used for infections of the bone, skin or soft tissue including burns. A bacterial infection is a condition in which bacteria grows in the body and cause infection. It can target any body part and multiply very quickly. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. These harmful bacteria produce chemicals known as toxins, which can damage tissue and make you sick.

TOBRANEG 80MG INJECTION contains tobramycin. It inhibits bacteria growth by interfering with protein synthesis. It binds to the proteins in the bacteria, disrupting the cell membrane, and eventually leading to cell death. It is active against various gram-negative bacteria and gram-positive bacteria (Staphylococcus aureus). It will not work for other types of infections such as viral, fungal, or parasitic infections.

It is available in the form of drops, ointment, injection, and inhalation. TOBRANEG 80MG INJECTION can cause some common side-effects (when eye drops are used) including redness, itching, swelling, burning sensation, tearing, and temporary blurred vision (with ointment use). Long term use of eye drops may cause a fungal eye infection. So, take this medicine for a duration prescribed by your doctor. When given as an injection, you may experience fever, rash, pain at the injection site, confusion, headache, and diarrhoea. Some patients may also experience serious side-effects such as hearing problems, muscle twitching, and convulsions that may require medical attention.

Inform your doctor if you are allergic to TOBRANEG 80MG INJECTION, other aminoglycoside antibiotics, or any other ingredients present in it. Inform your doctor if you are using other antibiotics, antifungal medication, antiviral drugs, diuretics, general anaesthetics, anti-cancer medicine, immune suppressant, and medications used to treat muscle weakness. Tell your doctor if you have myasthenia gravis (muscle disorders), Parkinson’s disease (a brain disorder), and kidney problems. Inform your doctor if you have any vision problems after using this medication. Tell your doctor if you are pregnant or breastfeeding.

Uses of TOBRANEG 80MG INJECTION

Bacterial infections

Directions for Use

Eye drops: Wash your hands thoroughly with water before and after use. Tilt your head back and pull down the lower eyelid to create a small sac. Take the prescribed amount of dose with the dropper and squeeze out a drop. Close your eyes for about 2 to 3 minutes. Wipe any excess liquid with a tissue. Do not wipe or rinse the dropper tip after use. Place the dropper back on the bottle and tighten the cap. Ointment: Eye ointment is also used similarly. Create a pocket pulling the lower eyelid while tilting your head back. Then, squeeze out a prescribed amount of ointment and close your eyes. You may experience blurred vision for some time after opening the eyes. So, rest for a while before doing anything. Injections: Injections are given using a syringe. Do not self-administer. Injections are given only by a healthcare professional. The prescribed dose is taken and injected into a muscle or vein. Infusions are given in the form of a drip into the vein by a healthcare professional. Inhalation: Inhalations are used by inhaling the medicine with the use of a nebulizer or inhaler. Do not mix or dilute the medicine unless advised by your doctor. Do not swallow it by mouth. Note: In case of drops/ointment, do not touch the tip of the dropper or ointment tube as it may contaminate the contents. Do not place the tip directly into the eye while instilling drops or ointment. If the dropper touches the eye, immediately squeeze two to three drops onto the tissue and wipe the dropper’s tip with saltwater.

Medicinal Benefits

TOBRANEG 80MG INJECTION belongs to a class of drugs called aminoglycoside antibiotics. It works by stopping the growth of bacteria. It reduces the infection by inhibiting bacterial growth. It irreversibly binds to a site on the bacterial ribosomes (ribosomes are responsible for protein synthesis), inhibiting protein formation. Proteins are essential for bacterial growth. So, if bacteria cannot make proteins, it will eventually die.

Side effects of Tobraneg 80mg Injection
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Drug Warnings

Inform your doctor if you are allergic to TOBRANEG 80MG INJECTION, other aminoglycoside antibiotics, or any other ingredients present in it. Inform your doctor if you are using any prescription, nonprescription medications, nutritional supplements, or herbal products. Inform your doctor if you are using other antibiotics, antifungal medication, diuretics, general anaesthetics, chemotherapeutic agents, immune suppressants, and medications used to treat muscle weakness. Inform your doctor if you have any history of myasthenia gravis, Parkinson’s diseases, kidney problems, and eye problems. Inform your doctor if you have any vision problems after using this medication. Do not drive or operate heavy machinery until your vision stabilizes. Tell your doctor if you are pregnant or breastfeeding.

Drug-Drug Interactions

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TobramycinCisatracurium
Severe

Drug-Drug Interactions

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How does the drug interact with Tobraneg 80mg Injection:
Coadministration of cidofovir with Tobraneg 80mg Injection can cause kidney problems.

How to manage the interaction:
Taking Tobraneg 80mg Injection with Cidofovir is not recommended, but can be taken if prescribed by a doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Do not stop using any medications without consulting a doctor.
TobramycinCisatracurium
Severe
How does the drug interact with Tobraneg 80mg Injection:
Combining Tobraneg 80mg Injection together with cisatracurium can increase the neuromuscular blocking effects( disorder that effects nerves and muscles) of cisatracurium.

How to manage the interaction:
Although there is a possible interaction between Cisatracurium and Tobraneg 80mg Injection, you can take these medicines together if prescribed by your doctor. If you have any of these symptoms - having trouble breathing contact your doctor right away. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobraneg 80mg Injection:
Using Tobraneg 80mg Injection together with everolimus can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Everolimus and Tobraneg 80mg Injection, you can take these medicines together if prescribed by a doctor. However, if you experience sudden weight gain, feeling out of breath, or having kidney problems. If you experience nausea, vomiting, loss of appetite, weight loss, swelling, muscle cramps, weakness, dizziness, confusion, or an irregular heartbeat contact a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobraneg 80mg Injection:
Taking Tobraneg 80mg Injection with Polymyxin B can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Tobraneg 80mg Injection and Polymyxin b, you can take these medicines together if prescribed by a doctor. However, if you experience hearing loss, ringing in the ears, difficulty breathing, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
TobramycinBumetanide
Severe
How does the drug interact with Tobraneg 80mg Injection:
When Tobraneg 80mg Injection is taken with Bumetanide, the amount of Tobraneg 80mg Injection in the blood can go up.

How to manage the interaction:
Although there is a possible interaction between Tobraneg 80mg Injection and Bumetanide, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Tobraneg 80mg Injection:
Taking Furosemide with Tobraneg 80mg Injection can increase the risk of hearing loss and kidney problems.

How to manage the interaction:
Although there is a possible interaction between Tobraneg 80mg Injection and Furosemide, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tobraneg 80mg Injection:
Coadministration of Tobraneg 80mg Injection with Sirolimus can cause an increased risk or severity of kidney problems.

How to manage the interaction:
Although taking Sirolimus and Tobraneg 80mg Injection together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, a decrease in hunger, increased or decreased urine, weight gain or loss that occurs suddenly, fluid retention, swelling, difficulty breathing, muscle pain, fatigue, weakness, dizziness, confusion, and irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Tobraneg 80mg Injection:
Takin human immunoglobulin with Tobraneg 80mg Injection may raise the risk of kidney problems.

How to manage the interaction:
Although taking Human immunoglobulin and Tobraneg 80mg Injection together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tobraneg 80mg Injection:
Taking Tobraneg 80mg Injection with succinylcholine can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
There may be a possibility of interaction between Suxamethonium and Tobraneg 80mg Injection, but it can be taken if prescribed by a doctor. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tobraneg 80mg Injection:
Using Vecuronium with Tobraneg 80mg Injection can increase the risk of respiratory depression(hypoventilation).

How to manage the interaction:
Co-administration of Tobraneg 80mg Injection with Vecuronium can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Sleep for at least six to eight hours to rejuvenate your eyes in a natural way.
  • Wash your eyes with clean water at least two to three times a day
  • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
  • Keep your ear clean and dry.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

TOBRANEG 80MG INJECTION is mostly used for the treatment of eye infections. It is not recommended for the treatment of ear infections. However, it should be used for any indication only when prescribed by a doctor.

TOBRANEG 80MG INJECTION may improve within 2 to 3 days of administration. However, recovery depends on different factors such as age, the severity of the infection, and comorbidities.

It is recommended to use TOBRANEG 80MG INJECTION in children only with a doctor's advice.

Do not take any medications without consulting a doctor if you are allergic to penicillin.

TOBRANEG 80MG INJECTION injection can cause hearing loss, especially in elderly people. It may be permanent sometimes. So, contact your doctor immediately if you have vertigo, dizziness, or tinnitus (ringing in the ears).

TOBRANEG 80MG INJECTION contains tobramycin which is an aminoglycoside antibiotic. It acts by inhibiting bacteria's growth. It binds to the proteins in the bacteria, disrupting the cell functions, and eventually leading to bacterial death.

Before using TOBRANEG 80MG INJECTION, you must inform your doctor if you have any allergy to TOBRANEG 80MG INJECTION or any antibiotics or if you are taking any other medicines.

Drug-Drug Interactions Checker List

  • VANCOMYCIN
  • KANAMYCIN
  • GENTAMICIN
  • STREPTOMYCIN
  • FUROSEMIDE
  • NEOSTIGMINE
  • PYRIDOSTIGMINE
  • CYCLOSPORINE
  • AMPHOTERICIN B
  • CISPLATIN
  • CEPHALOTHIN
  • ETHACRYNIC ACID

Special Advise

TOBRANEG 80MG INJECTION may alter liver and kidney function, and blood cells count. So, laboratory tests may be performed to monitor these levels. Your doctor may also check for vision and hearing problems. 

Disease/Condition Glossary

Conjunctivitis: Conjunctivitis is an eye condition caused by infection or allergies.

Meningitis: Meningitis is an infection of the protective membranes that surround the brain and spinal cord (meninges).

Pneumonia: Pneumonia is swelling (inflammation) of the tissue in one or both lungs. It's usually caused by a bacterial infection. It can also be caused by a virus, such as a coronavirus (COVID-19).

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