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Written By Divya L , PharmaD
Reviewed By Hari Kumar , MBBS
Non returnable*
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Composition :

OLANZAPINE-5MG

Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Tolaz DT 5 Tablet

Tolaz DT 5 Tablet belongs to a group of medicines called 'atypical antipsychotics,' primarily used to treat schizophrenia and manic depression (bipolar disorder). Schizophrenia is a mental condition in which the person may feel, hear or see things that are not there (hallucinations), believe things that are not true, and feel unusually suspicious or confused. Manic depression, or bipolar disorder, is a serious brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behavioural changes.

Tolaz DT 5 Tablet contains 'Olanzapine' that works by restoring the balance of chemical messengers (dopamine and serotonin) in the brain and improves thinking mood, and behaviour. It helps in clear thinking and decreases hallucinations. It is used for treating manic episodes of bipolar disorder and agitation in schizophrenia.

Take Tolaz DT 5 Tablet as prescribed by your doctor. Common side effects include drowsiness, dizziness, restlessness, tremors/shakiness, stomach upset, dry mouth, constipation, increased appetite, fatigue, decreased libido, swelling of the hands or feet, and weight gain. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Tolaz DT 5 Tablet is not recommended for treatment in patients with Dementia-Related Psychosis. Inform your doctor beforehand if you have a history of allergic reactions to Olanzapine, Alzheimer's disease, liver or kidney diseases, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, breast cancer, enlarged prostate, or fits before starting this medicine. If you are pregnant, planning to conceive, or a breastfeeding mother, inform your doctor before starting Tolaz DT 5 Tablet . Avoid consuming alcohol while being treated with Tolaz DT 5 Tablet as it can make you dizzy or drowsy. Do not drive or operate machinery while using Tolaz DT 5 Tablet since it can make you sleepy. This medicine is not recommended for children below 12 years of age.

Uses of Tolaz DT 5 Tablet

Schizophrenia and Manic depression (bipolar disorder).

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water. Do not crush, chew or break it. Melt in mouth tablets/Fast Dissolving tablets: Do not touch these tablets with wet hands. These tablets dissolve rapidly when placed on the tongue. Take the tablet and place it on your tongue. Let it disperse/dissolve in your oral cavity, and swallow it. There is no need to take these tablets with water.

Medicinal Benefits

Tolaz DT 5 Tablet is used to treat schizophrenia and manic depression (bipolar disorder). It effectively treats manic episodes of bipolar disorder and agitation in schizophrenia. It contains 'Olanzapine,' which belongs to the class of atypical antipsychotics. It works by restoring the balance of chemical messengers (dopamine and serotonin) in the brain. It is also known to improve thinking, mood, and behaviour. It helps in clear thinking and relieves psychotic symptoms like hallucinations.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tolaz DT 5 Tablet

  • Drowsiness
  • Dizziness
  • Restlessness
  • Tremors/shakiness
  • Stomach upset
  • Dry mouth
  • Constipation
  • Increased appetite
  • Fatigue
  • Decreased libido
  • Swelling of the hands or feet
  • Weight gain

Drug Warnings

Tolaz DT 5 Tablet is not recommended for treatment in patients with Dementia-Related Psychosis. Brief your medical history to the doctor if you have any allergic reactions, liver or kidney diseases, Alzheimer's disease, dementia, heart problems, breathing problems, high cholesterol, glaucoma, diabetes, bowel problems, breathing problem during sleep (sleep apnea), low white blood cell count, breast cancer, enlarged prostate, or fits before starting Tolaz DT 5 Tablet . Please consult your doctor if you are pregnant or planning to conceive before starting this medicine. Tolaz DT 5 Tablet is not recommended during breastfeeding. Avoid consuming alcohol as it might lead to increased side effects like dizziness and drowsiness. Avoid driving or operating machinery as Tolaz DT 5 Tablet may decrease your mental alertness, making you feel dizzy or drowsy. Tolaz DT 5 Tablet is not recommended for people below 12 years of age as safety and effectiveness have not been established.

Drug-Drug Interactions

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OlanzapineRopinirole
Critical
OlanzapinePotassium citrate
Critical

Drug-Drug Interactions

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OlanzapineRopinirole
Critical
How does the drug interact with Tolaz DT 5 Tablet:
When Ropinirole is taken with Tolaz DT 5 Tablet, it may reduce the effectiveness of ropinirole.

How to manage the interaction:
Taking Ropinirole with Tolaz DT 5 Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as drowsiness, low blood pressure, dizziness, and lightheadedness. Do not stop using any medications without consulting doctor.
OlanzapinePotassium citrate
Critical
How does the drug interact with Tolaz DT 5 Tablet:
Taking Tolaz DT 5 Tablet with Potassium citrate can increase the irritant effects of potassium on your stomach and upper intestine.

How to manage the interaction:
Co-administration of Tolaz DT 5 Tablet and Potassium citrate is not recommended as it leads to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapinePramipexole
Critical
How does the drug interact with Tolaz DT 5 Tablet:
Taking Tolaz DT 5 Tablet with Pramipexole can increase the risk and severity of side effects and reduce the effectiveness of Pramipexole.

How to manage the interaction:
Co-administration of Tolaz DT 5 Tablet and Pramipexole is not recommended as it leads to an interaction, it can be taken if advised by a doctor. If you experience any symptoms such as drowsiness, dizziness, and lightheadedness, contact a doctor immediately. Avoid driving or operating dangerous machinery, and be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
OlanzapinePotassium chloride
Critical
How does the drug interact with Tolaz DT 5 Tablet:
Taking Tolaz DT 5 Tablet with Potassium chloride can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Co-administration of Tolaz DT 5 Tablet and Potassium chloride is not recommended as it leads to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like severe abdominal pain, bloating, sudden dizziness or lightheadedness, nausea, vomiting (especially with blood), loss of appetite, and/or black, tarry stools, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
OlanzapineZonisamide
Severe
How does the drug interact with Tolaz DT 5 Tablet:
Coadministration of Tolaz DT 5 Tablet with Zonisamide can increase the risk or severity of Zonisamide side effects like increased body temperature and decreased sweating especially in warm weather.

How to manage the interaction:
Taking Tolaz DT 5 Tablet with Zonisamide together is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience changes in blood pressure, increased heart rate, fever, or excessive sweating, contact a doctor immediately. Make sure to hydrate yourself during warm weather or after exercise. Do not discontinue any medications without consulting a doctor.
OlanzapineTapentadol
Severe
How does the drug interact with Tolaz DT 5 Tablet:
Combining Tolaz DT 5 Tablet with Tapentadol can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, constipation, or problems with movement and memory.

How to manage the interaction:
Although taking Tolaz DT 5 Tablet and Tapentadol together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like difficulty breathing, dizziness, drowsiness, difficulty focusing, constipation, stomach ache or cramps, vomiting, or, feeling sick, contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
OlanzapineDiazepam
Severe
How does the drug interact with Tolaz DT 5 Tablet:
Taking diazepam together with Tolaz DT 5 Tablet can cause low blood pressure, weak pulse, shallow breathing, muscle weakness, drowsiness, dizziness and slurred speech.

How to manage the interaction:
Combining Tolaz DT 5 Tablet and Diazepam can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms consult the doctor immediately. Avoid activities requiring mental alertness until you know how these medications will affect you. Do not stop using any medications without first talking to your doctor.
OlanzapineKetamine
Severe
How does the drug interact with Tolaz DT 5 Tablet:
Using ketamine together with Tolaz DT 5 Tablet may increase side effects such as dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, and respiratory depression, impairment in thinking, judgment, and motor coordination.

How to manage the interaction:
Co-administration of ketamine of Tolaz DT 5 Tablet can lead to an interaction, it can be taken if advised by your doctor. If you experience any symptoms, contact your doctor immediately. Avoid alcohol and activities requiring mental alertness such as driving, operating hazardous machinery, or engaging in potentially hazardous activities until you know how the medications affect you. Do not discontinue any medications without consulting your doctor.
OlanzapineRemifentanil
Severe
How does the drug interact with Tolaz DT 5 Tablet:
Combining Tolaz DT 5 Tablet with Remifentanil can cause central nervous system depression such as Tolaz DT 5 Tablet can lead to serious side effects including respiratory distress, intestinal obstruction, fecal impaction.

How to manage the interaction:
Although taking Tolaz DT 5 Tablet and Remifentanil together can lead to an interaction, it can be taken if your doctor has suggested it. If you experience any symptoms like feeling tired, having trouble breathing, feeling dizzy or drowsy, difficulty focusing, taking pain or cough medications, constipation, blockage in your intestines, difficulty passing stool, hard or dry stool, less frequent bowel movements, stomach problems, feeling sick, feeling bloated, having stomach pain, or swelling contact the doctor immediately. you should avoid driving or operating hazardous machinery until you know how they affect you and do not discontinue any medications without consulting your doctor.
OlanzapineIohexol
Severe
How does the drug interact with Tolaz DT 5 Tablet:
The combined use of Iohexol and Tolaz DT 5 Tablet can increase the risk of seizures as Iohexol be injected directly into the spine.

How to manage the interaction:
Taking Tolaz DT 5 Tablet with Iohexol together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have seizures or a head injury, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain proper weight by following a healthy diet.
  • Exercise regularly as it helps in less cognitive decline and brain volume loss.
  • Avoid smoking and alcohol consumption.
  • Try to avoid stress by practising meditation or yoga.
  • Include fruits and vegetables in your diet as they contain antioxidants.
  • Eat nutritious food as it helps in cognitive stimulation.
  • Limit foods with high cholesterol and saturated fats.
  • Cut down on sugar, salt and processed foods.
  • Drink plenty of water.
  • Follow a healthy lifestyle as it helps in improving overall health and possibly protects the brain.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Tolaz DT 5 Tablet Substitute

Substitutes safety advice
  • Oleanz 5 Tablet 10's

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    5.31per tablet
  • Olimelt 5mg Tablet 10's

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    5.45per tablet
  • Olan-5 Tablet 10's

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    3.61per tablet
  • Oleanz RT 5 Tablet 10's

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    5.04per tablet
  • Oliza 5 Tablet 10's

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    5.45per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Tolaz DT 5 Tablet contains Olanzapine which works by balancing the chemical messengers like dopamine and serotonin located in the brain, improving mood, behaviour and thoughts.

Tolaz DT 5 Tablet should be used with caution in the medical history of allergic reactions, liver or kidney diseases, heart problems, breathing problems, Alzheimer's disease, high cholesterol, glaucoma, diabetes, stomach/intestinal problems, breathing problem during sleep (sleep apnea), low white blood cell count, breast cancer, enlarged prostate, or fits. Please let your doctor know if you have any other medical problems before starting Tolaz DT 5 Tablet .

Tolaz DT 5 Tablet may make you sweat less and can likely cause heart stroke. Hence, limiting activities that cause overheating, like an exercise in hot weather or using hot tubs, is advised. Drink plenty of fluids and dress lightly.

Tolaz DT 5 Tablet may cause dizziness. It is advised to avoid getting up too fast from a sitting or lying position that can make you feel dizzy.

Olanzapine can cause side effects like orthostatic hypotension (sudden lowering in blood pressure leading to dizziness on standing). If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Tolaz DT 5 Tablet are advised to regularly monitor their blood pressure levels to avoid such unpleasant events. It is also advised to be aware of a condition called tardive dyskinesia (uncontrolled movements of the face, lips, mouth, tongue, arms or legs) that may rarely occur while using this medicine.

Drug-Drug Interactions Checker List

  • CODEINE
  • HYDROCODONE
  • ALPRAZOLAM
  • LORAZEPAM
  • ZOLPIDEM
  • CARISOPRODOL
  • CYCLOBENZAPRINE
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • METOCLOPRAMIDE
  • ESCITALOPRAM
  • FLUOXETINE
  • SERTRALINE
  • QUETIAPINE

Special Advise

  • Let your doctor know that you are taking Tolaz DT 5 Tablet if you are undergoing any medical tests.
  • Weight gain has been noticed in patients who use Olanzapine; hence, please take measures accordingly.
  • High blood pressure is also recorded in patients using this medicine; hence take appropriate measures accordingly by consulting your doctor.
  • Tolaz DT 5 Tablet may affect blood glucose levels. Hence it is advised to monitor blood sugar levels regularly while using Tolaz DT 5 Tablet . 
  • Timely monitoring of the cholesterol/triglyceride levels and Prolactin hormone levels is advised for the patient while using this medicine.

Disease/Condition Glossary

Schizophrenia: It is a condition in which the person may see, hear or feel things that are not there, believe things that are not true, or feel unusually suspicious or confused. Symptoms include hallucinations, delusions, thought disorders, movement disorders, disorganised thinking, loss of interest, lack of emotions, etc. Schizophrenia is triggered by physical, genetic, psychological, and environmental factors. Patients suffering from this disease may require lifelong treatment. Treatment involves a combination of medications, psychotherapy and care services.

Manic depression (bipolar disorder): A serious brain disorder in which a person goes through unusual mood changes (mood swings) and frequent changes in his/her behaviour and thinking.

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