Tolkem D Tablet 10's belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killer. Tolkem D Tablet 10's is used to reduce and relieve pain due to the muscle spasms (excessive tension in the muscles). Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

Tolkem D Tablet 10's is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effect, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement.

Take Tolkem D Tablet 10's as prescribed by your doctor. You are advised to take Tolkem D Tablet 10's for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, diarrhoea, vomiting, heartburn, weakness, stomach pain/epigastric pain, sleepiness, dizziness, and appetite loss. Most of these side effects of Tolkem D Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Tolkem D Tablet 10's can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Tolkem D Tablet 10's. Tolkem D Tablet 10's increases the chances of stomach ulcers and bleeding.  Before taking this Tolkem D Tablet 10's, inform your doctor if you have any allergies, myasthenia gravis (weakness in muscles), asthma, and hay fever. To treat your condition effectually, continue taking Tolkem D Tablet 10's for as long as your doctor has prescribed. Do not take Tolkem D Tablet 10's if you are pregnant or breastfeeding unless prescribed. Tolkem D Tablet 10's causes drowsiness and dizziness, so drive with caution. Tolkem D Tablet 10's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with Tolkem D Tablet 10's as it could lead to increased drowsiness and dizziness, it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Tolkem D Tablet 10's belongs to a class of medications called Non-steroidal anti-inflammatory drugs (NSAIDs) or pain killers. Tolkem D Tablet 10's is a combination of two drugs, namely: Diclofenac and Tolperisone. Diclofenac is a pain killer (NSAIDs) while Tolperisone is a skeletal muscle relaxant. Diclofenac works by blocking the effect of a chemical messenger in your body, known as cyclo-oxygenase (COX) enzymes that make another chemical 'prostaglandins' (PG). These prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzyme's effects, lesser PGs are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. On the other hand, Tolperisone works on the brain and spinal cord centres to relieve muscle stiffness or spasm and relieve pain and improve muscle's movement. Altogether Tolkem D Tablet 10's relieves pain and relaxes the muscles.

• Nausea
• Diarrhoea
• Vomiting
• Loss of appetite
• Heartburn
• Weakness
• Stomach pain/epigastric pain
• Sleepiness
• Dizziness
• Numbness and tingling
• Ringing in the ears

Tolkem D Tablet 10's can increase your risk of fatal heart attack or stroke. So, if you have had any recent heart surgery, do not use Tolkem D Tablet 10's. Do not take Tolkem D Tablet 10's if you are allergic to Tolkem D Tablet 10's, have severe heart failure, have suffered bleeding problems such as bleeding from stomach or bowels while taking any pain killers or you have liver or kidney problems. Inform your doctor before taking Tolkem D Tablet 10's if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver and kidney problems. Do not take Tolkem D Tablet 10's if you are pregnant or breastfeeding unless prescribed. Tolkem D Tablet 10's causes drowsiness and dizziness, so drive only if you are alert. Tolkem D Tablet 10's should not be given to children as the safety have not been established. Avoid consuming alcohol and Tolkem D Tablet 10's as it could lead to increased drowsiness and increase the risk of stomach bleeding. Stop taking Tolkem D Tablet 10's and consult your doctor immediately if you have stomach pain or any signs of bleeding in intestine or stomach such as blood in stools. Do not take any other NSAID's for pain relief along with Tolkem D Tablet 10's unless prescribed. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions: Tolkem D Tablet 10's may have interaction with anti-gout medicine (allopurinol, Probenecid), pain killers (aspirin), medicine for reducing immune system (cyclosporine), blood pressure-lowering medicine (furosemide), and medicines used in cancer (Methotrexate), other muscle relaxants (Methocarbamol)

Drug-Food Interactions: Avoid alcohol consumption while taking Tolkem D Tablet 10's as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: Tolkem D Tablet 10's may have interactions with anaemia, muscle weakness, asthma, fluid retention, hyperkalemia (high potassium levels), heart, kidney, and liver problems.

• ALLOPURINOL
• ASPIRIN
• CYCLOSPORINE
• FUROSEMIDE
• METHOTREXATE

• Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
• Massages can also be helpful.
• Avoid freezing and hot temperatures.
• Avoid wearing tight-fitting clothes, instead, wear loose garments.
• Rest well, get plenty of sleep.
• To avoid developing pressure sores, change your position at least every two hours.
• Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
• Stay hydrated, drink plenty of water.

•  Applying ice pack to the affected area may help in relieving pain and inflammation.
• Avoid grapefruit juice.

Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty moving, pain in affected muscles and joints. Fatigue (weakness), stress, extreme heat or cold, infection, and tight clothing can trigger muscle spasms. Muscle relaxants and exercise can treat muscle spasms. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. Whereas, exercise helps in muscle stretching to be less likely to spasm, tear and sprain.