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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

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Not Returnable

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About Tonact ASP 150 Capsule

Tonact ASP 150 Capsule is a combination drug of blood-thinning agents and cholesterol-lowering agents, primarily taken for the prevention of heart attack and stroke. It also lowers the raised level of bad cholesterol (especially those who are at high risk of heart diseases). A heart attack generally refers to a blocked flow of blood to the heart due to the blockage of arteries. The blockage is most often a build-up of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Tonact ASP 150 Capsule is composed of two medicines namely: Atorvastatin and Aspirin. Atorvastatin is a lipid-lowering medication which blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (also known as low-density lipoproteins or LDL), and triglycerides (TG) and increases the levels of good cholesterol (also known as high-density lipoproteins or HDL). Aspirin is a blood thinner or anti-platelet (anticoagulant) that collectively prevent the formation of clot in the blood vessels. Together Tonact ASP 150 Capsule help to reduce the risk of heart attack, stroke, and heart-related chest pain (angina). Additionally, it is also given to the patients who had a recent heart bypass surgery (CABG) to control the level of cholesterol and prevent blood clots.

Your doctor will advise you on how often you take your tablets based on your medical condition. In some cases, you may experience headache, ankle swelling (oedema), dark urine, muscle weakness, slow heart rate, dizziness, and nausea. Most of these side effects of Tonact ASP 150 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Stopping Tonact ASP 150 Capsule abruptly may worsen your condition and increase your risk of future heart attack. Let your doctor know if are sensitive to atorvastatin, or aspirin, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), muscle problems (myopathy, rhabdomyolysis), are pregnant or planning to become pregnant or breastfeeding. Patients should inform the doctor that they are taking Tonact ASP 150 Capsule before any surgery is scheduled or any new medicine is taken. Atorvastatin present in Tonact ASP 150 Capsule is a pregnancy category X drug so it is contraindicated in pregnant women. As it may cause harm to the fetus if administered to a pregnant woman. Inform your doctor that you are taking Tonact ASP 150 Capsule if you are going to have any surgery.

Uses of Tonact ASP 150 Capsule

Prevention of heart attack and stroke.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Tonact ASP 150 Capsule is composed of two medicines: Atorvastatin and Aspirin. Atorvastatin is a lipid-lowering medication and it blocks the enzyme required to make cholesterol in the body. It reduces the bad cholesterol (low density lipoproteins or LDL), triglycerides (TG) and increases the levels of good cholesterol (high density lipoproteins or HDL). Besides this, Aspirin prevents the formation of clot in the blood vessels. Together Tonact ASP 150 Capsule prevents risk of any heart attack or stroke in future.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tonact ASP 150 Capsule

  • Headache
  • Ankle swelling (oedema)
  • Dark urine
  • Muscle weakness
  • Slow heart rate
  • Dizziness
  • Nausea

Drug Warnings

Let your doctor know if you are highly sensitive to atorvastatin, or aspirin, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), pregnant or planning to become pregnant, or breastfeeding. The patient should inform the doctor that they are taking Tonact ASP 150 Capsule before any surgery is scheduled or any new medicine is taken. Atorvastatin present in Tonact ASP 150 Capsule is a pregnancy category X drug so it is contraindicated in pregnant women. Tonact ASP 150 Capsule contains Atorvastatin which can cause muscle problems like myopathy and rhabdomyolysis. So, any signs of muscle pain, tenderness, or weakness, during the initial months of the treatment should be closely monitored. Safety and effectiveness of Tonact ASP 150 Capsule have not been established, so its use should be avoided in paediatric patients or children less than 12 years of age. Abrupt discontinuation of Tonact ASP 150 Capsule may lead to the occurrence of cardiovascular events like heart attack, stroke, and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Tonact ASP 150 Capsule .

Drug-Drug Interactions

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AtorvastatinPosaconazole
Critical
AspirinKetorolac tromethamine
Critical

Drug-Drug Interactions

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AtorvastatinPosaconazole
Critical
How does the drug interact with Tonact ASP 150 Capsule:
Taking Tonact ASP 150 Capsule with Posaconazole can increase the blood levels of Tonact ASP 150 Capsule. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Tonact ASP 150 Capsule, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AspirinKetorolac tromethamine
Critical
How does the drug interact with Tonact ASP 150 Capsule:
Combining Ketorolac tromethamine with Tonact ASP 150 Capsule can increase the risk of adverse effects.

How to manage the interaction:
Taking Tonact ASP 150 Capsule with Ketorolac tromethamine is not recommended, as it results in an interaction, it can be taken if advised by a doctor. Do not stop using any medications without a doctor’s advice.
AspirinKetorolac
Critical
How does the drug interact with Tonact ASP 150 Capsule:
Co-administration of Ketorolac and Tonact ASP 150 Capsule may increase the risk of side effects.

How to manage the interaction:
Taking Ketorolac with Tonact ASP 150 Capsule is not recommended but can be taken together if prescribed by a doctor. However, consult a doctor if you experience unusual bleeding or bruising, dizziness, tarry stools, coughing up or vomiting fresh or dried blood, severe headache and weakness. Do not stop using any medications without talking to a doctor.
AtorvastatinDarunavir
Severe
How does the drug interact with Tonact ASP 150 Capsule:
Combining Tonact ASP 150 Capsule with darunavir may profoundly enhance Tonact ASP 150 Capsule levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Tonact ASP 150 Capsule with darunavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinRifampicin
Severe
How does the drug interact with Tonact ASP 150 Capsule:
Taking Tonact ASP 150 Capsule with rifampicin can decrease the blood levels of Tonact ASP 150 Capsule, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Tonact ASP 150 Capsule and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AtorvastatinFenofibrate
Severe
How does the drug interact with Tonact ASP 150 Capsule:
Coadministration of Fenofibrate with Tonact ASP 150 Capsule can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although taking Fenofibrate and Tonact ASP 150 Capsule together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinTipranavir
Severe
How does the drug interact with Tonact ASP 150 Capsule:
Using tipranavir together with Tonact ASP 150 Capsule may significantly increase the blood levels of Tonact ASP 150 Capsule.

How to manage the interaction:
Although taking Tipranavir and Tonact ASP 150 Capsule together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AtorvastatinRanolazine
Severe
How does the drug interact with Tonact ASP 150 Capsule:
Co-administration of Tonact ASP 150 Capsule with Ranolazine can possibly lead to elevated levels of Tonact ASP 150 Capsule in blood.

How to manage the interaction:
Co-administration of Tonact ASP 150 Capsule with Ranolazine can result in an interaction. It can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not discontinue the medications without consulting.
AtorvastatinSimeprevir
Severe
How does the drug interact with Tonact ASP 150 Capsule:
Using Tonact ASP 150 Capsule together with simeprevir may significantly increase the blood levels of Tonact ASP 150 Capsule.

How to manage the interaction:
Although taking Tonact ASP 150 Capsule and Simeprevir together can cause an interaction, it can be taken if a doctor has suggested it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
AtorvastatinAmprenavir
Severe
How does the drug interact with Tonact ASP 150 Capsule:
Using Tonact ASP 150 Capsule together with amprenavir may significantly increase the blood levels of Tonact ASP 150 Capsule.

How to manage the interaction:
Although taking Tonact ASP 150 Capsule and Amprenavir together can cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on your health and talk to a doctor about any concerns. If you notice any of these signs - muscle pain, dark urine, fever, or fatigue - make sure to contact a doctor right away. They can help figure out what's going on and how to help you feel better. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet especially rich in soluble fibre like beans, legumes, whole grain, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short span of time. Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and low in red meat and most dairy.
  • Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants which help to lower LDL - low density lipoprotein (bad cholesterol)
  • Minimize the intake of added sugar. The American Heart Association (ADA) recommends, one should not eat more than 100 calories (25 grams) of added sugar for women and childraen, and no more than 150 calories (37.5 grams) for men every day.
  • American Heart Association recommends the intake of sodium chloride (table salt) should not exceed more than 2,300 mg per day as part of a healthy eating pattern.
  • As a precautionary measure, do not consume alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

Tonact ASP 150 Capsule Substitute

Substitutes safety advice
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  • Atorva ASP 150 Capsule 10's

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    4.46per tablet
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    3.02per tablet
  • Optor-ASP 150 Capsule 15's

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    3.60per tablet
  • Ctor Asp 10 mg/150 mg Tablet

    by Others

    7.40per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Yes, the use of Tonact ASP 150 Capsule can cause dizziness in some patients. They may experience symptoms such as feeling of fainting, weakness, or lightheadedness. In case you experience such symptoms, it is better to rest for some time until you feel better.

Usually Tonact ASP 150 Capsule is prescribed for a long term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.

Yes, Tonact ASP 150 Capsule is known to cause upset stomach. So, it should be taken with food so as to avoid discomfort. If even then, problem persists, please consult your doctor for best advise. In rare cases gastro intestinal bleeding can be observed due to blood thinning action of aspirin present in Tonact ASP 150 Capsule .

There's no strong evidence to suggest that taking Tonact ASP 150 Capsule will reduce fertility in either men or women. However, it is advisable to consult a doctor before taking it if you're likely to get pregnant or pregnant.

Yoghurt has the ability to lower cholesterol to its probiotic content. Yoghurt eaters have a better metabolic profile than those who didn't eat yoghurt.

Tonact ASP 150 Capsule can raise your blood sugar (H1b1AC) a little. If you already have type 2 diabetes please consult your doctor. The doctor will weigh the benefits and any potential risks before prescribing it to you.

Tonact ASP 150 Capsule contains aspirin which can increased your risk of bleeding. Please consult your doctor if Tonact ASP 150 Capsule needs to be stopped before undergoing surgery. The doctor might ask you to stop taking Tonact ASP 150 Capsule few days before surgery to avoid the increased risk of bleeding during the procedure.

Yes, taking Tonact ASP 150 Capsule can increase the risk of bleeding as it contains aspirin which is a blood thinner. So, please be very caution while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding.

Prolonged intake of statins causes musculo skeletal problems or muscle weakness problems like myopathy and rhabdomyolysis. So, you can reach out to doctor if you have any muscle pain or weakness after taking Tonact ASP 150 Capsule .

Drug-Drug Interactions Checker List

  • CLARITHROMYCIN
  • RITONAVIR
  • LOPINAVIR
  • DARUNAVIR
  • ATAZANAVIR
  • INDINAVIR
  • ITRACONAZOLE
  • WARFARIN
  • HEPARIN
  • COLCHICINE
  • DIGOXIN
  • CYCLOSPORINE

Disease/Condition Glossary

Atherosclerosis occurs when fats, cholesterol and other substances known as plaque deposits on your artery walls that restrict blood flow. This plaque formation triggers blood clot, narrow the arteries size and makes it hardened. This in turn can lead to various heart complications like heart attack, heart-related chest pain (angina) and stroke. However, it can also affect the arteries of body apart from the heart.

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