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Reviewed By Sunny S , MBBS
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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Tonact EZ 40 Tablet 10's

Tonact EZ 40 Tablet 10's belongs to a class of medications called HMG-CoA reductase inhibitors (statins)’ and ‘sterol absorption inhibitor’ Tonact EZ 40 Tablet 10's is primarily used to treat high cholesterol levels. Dyslipidaemia (high cholesterol level) is the deposition of unhealthy levels of fats (lipid) in the blood. In this condition, there is always a high level of low-density lipoprotein (LDL or bad cholesterol), triglycerides (TG), and a low level of high-density lipoprotein (HDL or good cholesterol).

Tonact EZ 40 Tablet 10's is a combination of two medicines: Atorvastatin (HMG-CoA reductase inhibitors (statins)) and Ezetimibe (sterol absorption inhibitor). Atorvastatin helps to decrease the production of cholesterol that may build up on the blood vessels (arteries) of the heart, brain, and other parts of the body. By lowering cholesterol levels, they help prevent the chance of having heart diseases such as heart attacks and strokes in the future. On the other hand, Ezetimibe is a cholesterol absorption inhibitor that avoids the absorption of cholesterol from the intestines. Together, they provide a better decrease in cholesterol in your body.

Take Tonact EZ 40 Tablet 10's as prescribed by your doctor. You are advised to take Tonact EZ 40 Tablet 10's for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience nausea, stomach pain, constipation, muscle pain, headache, the increased glucose level in the blood, increased liver enzymes. Most of these side effects of Tonact EZ 40 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. You should contact a doctor before if you have liver or kidney problems, severe lung disease. If you have a muscle problem, inform your doctor. If you are pregnant, planning to become pregnant, or breastfeeding then immediately inform your doctor because Tonact EZ 40 Tablet 10's contains Atorvastatin that may harm an unborn baby. Do not take this Tonact EZ 40 Tablet 10's if you have a previous heart attack or stroke caused by bleeding in the brain, have hypothyroidism, drink more than 2 servings of alcohol per day, and have a muscle disorder (fibromyalgia). The efficiency of Tonact EZ 40 Tablet 10's can be increased by taking low fat or cholesterol-containing food and drinks. 

Uses of Tonact EZ 40 Tablet 10's

Lowering of an increased level of cholesterol.

Directions for Use

Swallow Tonact EZ 40 Tablet 10's as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Tonact EZ 40 Tablet 10's taken with dietary measures helps in the treatment of high cholesterol especially for heart patients when initial dietary measures fail to lower cholesterol. Tonact EZ 40 Tablet 10's contains Atorvastatin which helps lower the bad cholesterol (LDL) and increases the level of good cholesterol (HDL) in the state of dyslipidemia or hyperlipidemia. Tonact EZ 40 Tablet 10's also lowers the amount of fat or cholesterol deposition (plaque) in the arteries of the heart thereby reducing the chance of having a heart attack or stroke in the future. Tonact EZ 40 Tablet 10's contains Ezetimibe which is a cholesterol absorption inhibitor that avoids absorption of cholesterol from the intestines. Together, they provide a better decrease in cholesterol in your body.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Tonact EZ 40 Tablet 10's

  • Nausea
  • Stomach pain
  • Constipation
  • Muscle pain
  • Headache
  • Increased glucose level in blood
  • Increased liver enzymes.

Drug Warnings

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. You should contact a doctor before if you have liver or kidney problems, severe lung disease. If you have a muscle problem, inform your doctor. Do not take this Tonact EZ 40 Tablet 10's if you have a previous heart attack or stroke caused by bleeding in the brain, have hypothyroidism, drink more than 2 servings of alcohol per day, and have a muscle disorder (fibromyalgia). The efficiency of Tonact EZ 40 Tablet 10's can be increased by taking low fat or cholesterol-containing food and drinks. Tonact EZ 40 Tablet 10's is not safe for children as safety and efficacy of Tonact EZ 40 Tablet 10's in children have not established. Tonact EZ 40 Tablet 10's has Ezetimibe which contains a sugar called lactose. If you have been told by your doctor that you have an intolerance to some sugars, talk to your doctor before taking this Tonact EZ 40 Tablet 10's. If you are pregnant, planning to become pregnant, then immediately inform your doctor because Tonact EZ 40 Tablet 10's contains Atorvastatin that may harm an unborn baby. If you are a breastfeeding mother, then immediately contact your doctor as it is unknown if this Tonact EZ 40 Tablet 10's passes into breast milk.

Drug-Drug Interactions

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AtorvastatinPosaconazole
Critical
AtorvastatinDarunavir
Severe

Drug-Drug Interactions

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AtorvastatinPosaconazole
Critical
How does the drug interact with Tonact EZ 40 Tablet:
Taking Tonact EZ 40 Tablet with Posaconazole can increase the blood levels of Tonact EZ 40 Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Tonact EZ 40 Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AtorvastatinDarunavir
Severe
How does the drug interact with Tonact EZ 40 Tablet:
Combining Tonact EZ 40 Tablet with darunavir may profoundly enhance Tonact EZ 40 Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Tonact EZ 40 Tablet with darunavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinNicotinic acid
Severe
How does the drug interact with Tonact EZ 40 Tablet:
Combining Tonact EZ 40 Tablet with nicotinic acid may raise the risk of rhabdomyolysis, (an uncommon illness that leads to the destruction of skeletal muscle tissue). If you are elderly or have preexisting kidney disease, you may be at higher risk. This interaction is only relevant if you are taking large doses of nicotinic acid to treat high cholesterol. It does not apply if you are taking nicotinic acid in nutritional supplement amounts.

How to manage the interaction:
Taking Tonact EZ 40 Tablet and nicotinic acid together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you happen to experience, unexplained muscle pain, tenderness, weakness, fever, dark coloured urine, light coloured stools, you are advised to seek immediate medical attention. Do not discontinue any medications without consulting a doctor.
AtorvastatinGemfibrozil
Severe
How does the drug interact with Tonact EZ 40 Tablet:
When Gemfibrozil is taken with Tonact EZ 40 Tablet, the chance of side effects such as liver damage and rhabdomyolysis, (an uncommon illness involving the breakdown of skeletal muscle tissue) increases.

How to manage the interaction:
Co-administration of Tonact EZ 40 Tablet along with Gemfibrozil together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinClofibrate
Severe
How does the drug interact with Tonact EZ 40 Tablet:
Using clofibrate together with Tonact EZ 40 Tablet can increase the risk of side effects.

How to manage the interaction:
Co-administration of Clofibrate with Tonact EZ 40 Tablet can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and contact a doctor right away if you notice any of these signs - liver problems, muscle damage, kidney problems, complications, pain, weakness, fever, dark urine, chills, joint pain, swelling, bruising, rash, itching, loss of appetite, tiredness, feeling sick, throwing up, or bleeding. Do not stop using any medications without a doctor's advice.
AtorvastatinClarithromycin
Severe
How does the drug interact with Tonact EZ 40 Tablet:
Co-administration of Tonact EZ 40 Tablet with Clarithromycin possibly enhances Tonact EZ 40 Tablet levels in the blood. This can raise the chance of side effects (liver damage and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Tonact EZ 40 Tablet if prescribed by the doctor. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinErlotinib
Severe
How does the drug interact with Tonact EZ 40 Tablet:
Coadministration of Erlotinib with Tonact EZ 40 Tablet can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Erlotinib with Tonact EZ 40 Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
AtorvastatinAtazanavir
Severe
How does the drug interact with Tonact EZ 40 Tablet:
Combining Tonact EZ 40 Tablet with atazanavir may drastically elevate Tonact EZ 40 Tablet levels in the blood. This can raise the chance of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Tonact EZ 40 Tablet with atazanavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinKetoconazole
Severe
How does the drug interact with Tonact EZ 40 Tablet:
Using Tonact EZ 40 Tablet with ketoconazole, may raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Tonact EZ 40 Tablet with ketoconazole can result in an interaction, it can be taken if a doctor has recommended it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not discontinue any medication without consulting a doctor.
AtorvastatinRifampicin
Severe
How does the drug interact with Tonact EZ 40 Tablet:
Taking Tonact EZ 40 Tablet with rifampicin can decrease the blood levels of Tonact EZ 40 Tablet, which may make the medication less effective.

How to manage the interaction:
Although there is an interaction between Tonact EZ 40 Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try aromatherapy, yoga, meditation to help relax your body and mind.
  • Try to do breathing exercises to get more oxygen.
  • Eat a healthy diet especially rich in soluble fibre like beans, legumes, whole grain, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short span of time. Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and low in red meat and most dairy.
  • Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants that help to lower LDL
  • Minimize the intake of added sugar. The American Heart Association (ADA) recommends, one should not eat more than 100 calories (25 grams) of added sugar for women and children, and no more than 150 calories (37.5 grams) for men every day.
  • American Heart Association recommends the intake of sodium chloride (table salt) should not exceed more than 2,300 mg per day as part of a healthy eating pattern.
  • As a precautionary measure, do not consume alcohol and quit smoking.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

Tonact EZ 40 Tablet 10's Substitute

Substitutes safety advice
  • Lipi EZ 40 Tablet 10's

    by Others

    39.24per tablet
  • Atorva E 40 Tablet 10's

    by Others

    36.95per tablet
  • Minilip EZ Tablet 10's

    by Others

    23.31per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • POSACONAZOLE
  • RITONAVIR
  • ATAZANAVIR
  • GEMFIBROZIL
  • TELITHROMYCIN
  • CYCLOSPORINE
  • TELAPREVIR
  • DAPTOMYCIN
  • GLECAPREVIR+PIBRENTASVIR

Disease/Condition Glossary

Cholesterol is a waxy substance produced by the liver to protect nerves, make tissue, and various hormones. Our body also receives cholesterol from the food we eat like cooking oils, eggs, meats, and dairy products. Excess cholesterol is bad for our health. There are two types of cholesterol namely 'bad cholesterol' and 'good cholesterol'. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG) while good cholesterol consists of high-density lipoprotein (HDL). Usually, there are no specific symptoms of raised or high levels of cholesterol but a large deposition of cholesterol in the arteries (plaque) or heart blockage. Blocked artery or plaque formation in the arteries of the heart can lead to chest pain (angina), heart attack, or stroke. So, it is advisable to have complete cholesterol tests (lipid profile test) at least once a year. It will help you to closely monitor your heart health and risk of heart attack and stroke.

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