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Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

TOPIRAMATE-50MG

Manufacturer/Marketer :

Johnson & Johnson Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Topamac 50 mg Tablet

Topamac 50 mg Tablet belongs to a group of medicines called “antiepileptic (AED)/ anticonvulsant agent' that is primarily indicated in the treatment of epilepsy (Monotherapy and Adjunctive therapy) and It can also be taken to prevent migraine. Epilepsy is a chronic disorder that is responsible for causing unprovoked, recurrent seizures in the body. A seizure is a sudden attack in the brain that makes a person lose control of their actions. Migraine is a mental condition that often causes intense or debilitating headaches with difficulty speaking, nausea, vomiting, and sensitivity to light or sound.

Topamac 50 mg Tablet is responsible for restoring the balance of neural activity by diminishing the spread of seizure movement in the brain. By controlling the electrical activity of the brain, it controls seizures and relieves the symptoms of migraine. Take Topamac 50 mg Tablet in an empty stomach without food with one glass of water. Topamac 50 mg Tablet is only available on prescription. It comes as tablets or capsules intended to be taken by mouth only. Swallow the medication as a whole without crushing or breaking it. Topamac 50 mg Tablet doses are sometimes advised according to the weight of children so the doctor will change the dose if the child gains or lose weight.

The possible side effects of topiramate include feeling sleepy, dizziness, diarrhoea and feeling sick. Some of the side effects do not even require medical attention and these are usually mild and go away by themselves. Consult with the doctor if any of these side effects continue or get worse with time.

The use of $mame is restricted in persons who are hypersensitive to it, so tell your doctor if you have any allergy to any of the chemical constituents present in this medicine. Tell your doctor if you ever had or already dealing with diarrhoea, glaucoma, metabolic acidosis, lung disease, breathing problems, liver disease, a blood disorder called acute porphyria etc. If a woman is pregnant or planning to pregnant then they should tell their doctor as the use of this medicine during pregnancy may increase the risk of cleft lip and/or cleft palate which is a birth defect in the newborn that may develop during early pregnancy.

Uses of Topamac 50 mg Tablet

Epilepsy, Migraine

Directions for Use

Tablet: It can be taken irrespective of meals. Swallow the tablet as a whole with a glass of water. Do not chew the tablet. Sprinkle capsule: You may swallow the capsule as a whole or you may open the capsule and sprinkle the entire contents on a teaspoon of soft food. Drink fluids immediately after eating this medicine and food mixture to make sure it is swallowed. Do not store this mixture for later use.

Medicinal Benefits

Topamac 50 mg Tablet is an antiepileptic (AED) medicine that is used to treat epilepsy in mono or adjunctive therapy and migraine. In Monotherapy epilepsy, Topamac 50 mg Tablet is suggested for patients above 2 years of age with partial-onset or primary generalized tonic-clonic seizures. In Adjunctive therapy epilepsy, Topamac 50 mg Tablet is suggested in patients of 2 to 16 years of age with partial-onset seizures or primary generalized tonic-clonic seizures while in patients more than 2 years of age, Topamac 50 mg Tablet is suggested in patients with seizures associated with Lennox-Gastaut syndrome (LGS). In migraine, Topamac 50 mg Tablet is suggested for prophylaxis of migraine. Topamac 50 mg Tablet works by blocking the voltage-dependent sodium and calcium channels and increasing the inhibitory actions of GABA. In epilepsy, Topamac 50 mg Tablet controls the uncontrolled activity of nerves in the brain and thus prevents or controls seizures. While in migraine, Topamac 50 mg Tablet tranquilizes the overactive nerve cells in the brain that are responsible for causing migraine.

Storage

Store in a cool and dry place away from sunlight
Side effects of Topamac 50 mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Drug Warnings

Topamac 50 mg Tablet may cause a congenital disability called cleft lip in unborn baby, so the use of this medicine is not allowed in pregnant females. Topamac 50 mg Tablet may increase the body temperature and reduce sweating, so one should report it to the doctor if they are noticing decreased sweating and hot, dry skin. Topamac 50 mg Tablet may enhance the level of acid in the blood so one should tell their doctor if they have irregular heartbeats or loss of hunger. Before taking Topamac 50 mg Tablet , tell the doctor if you have diarrhoea, metabolic acidosis, eye problems, liver disease. Topamac 50 mg Tablet may affect the working of contraceptives that include the combined pill, vaginal ring, patches,progestogen-only contraceptive pill, and emergency contraception. So, one should tell their doctor if they are using any contraceptives to prevent pregnancy.

Drug-Drug Interactions

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TopiramateProtriptyline
Severe

Drug-Drug Interactions

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TopiramateProtriptyline
Severe
How does the drug interact with Topamac 50 mg Tablet:
Combining Topamac 50 mg Tablet with Protriptyline can increase the risk of CNS depression.

How to manage the interaction:
Although there is a possible interaction between Topamac 50 mg Tablet and Protriptyline, you can take these medicines together if prescribed by your doctor. Your doctor can recommend other options that won't cause problems when taken together. It's important to be careful and keep a close eye on things. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Topamac 50 mg Tablet:
Co-administration of Topamac 50 mg Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like Phenylephrine.

How to manage the interaction:
Although there is a possible interaction between Phenylephrine and Topamac 50 mg Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Topamac 50 mg Tablet:
Combining Imipramine with Topamac 50 mg Tablet can increase the risk of overheating and reduced sweating.

How to manage the interaction:
There may be a possibility of interaction between Topamac 50 mg Tablet and Imipramine, but it can be taken if prescribed by a doctor. When taken together, your doctor can recommend other options that won't cause any problems. Just be careful and make sure to keep an eye out for any signs of reduced sweating and high body temperature. Do not discontinue any medications without consulting a doctor.
TopiramateOrphenadrine (chloride)
Severe
How does the drug interact with Topamac 50 mg Tablet:
Topamac 50 mg Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with orphenadrine.

How to manage the interaction:
There may be a possibility of interaction between Orphenadrine (chloride) and Topamac 50 mg Tablet, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
TopiramateDesipramine
Severe
How does the drug interact with Topamac 50 mg Tablet:
Topamac 50 mg Tablet can cause increased body temperature and decreased sweating, and these effects may be worsened when combined with medications like desipramine.

How to manage the interaction:
Although there is a possible interaction between Topamac 50 mg Tablet and Desipramine, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without talking to your doctor.
How does the drug interact with Topamac 50 mg Tablet:
The combined use of Metformin with Topamac 50 mg Tablet may increase the risk of Lactic acidosis (excessive lactic acid production in the blood).

How to manage the interaction:
Coadministration Metformin with Topamac 50 mg Tablet can lead to an interaction, it can be taken if prescribed by a doctor. However, if you experience symptoms such as weakness, muscle pain, respiratory distress, consult the doctor immediately. Do not stop using any medication without a doctor's advice.
How does the drug interact with Topamac 50 mg Tablet:
When Desogestrel is taken with Topamac 50 mg Tablet may reduce the blood levels and effects of Desogestrel.

How to manage the interaction:
There may be a possibility of interaction between Desogestrel and Topamac 50 mg Tablet, but it can be taken if prescribed by a doctor. If you notice any of these symptoms or if you're looking for other birth control options, it's important to contact your doctor right away. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Topamac 50 mg Tablet:
Taking Topamac 50 mg Tablet with meclizine can cause increased body temperature and decreased sweating.

How to manage the interaction:
Although there is a interaction between Meclizine and Topamac 50 mg Tablet, but it can be taken together if prescribed by your doctor. However, if you experience drowsiness, dizziness, or lightheadedness, increased body temperature and decreased sweating contact your doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Topamac 50 mg Tablet:
Topamac 50 mg Tablet may lower the blood levels and effects of levonorgestrel, making it less effective as a type of birth control.

How to manage the interaction:
Although taking levonorgestrel and Topamac 50 mg Tablet can lead to an interaction, it can be taken if prescribed by a doctor. If you have been receiving hormone replacement therapy (Levonorgestrel) for menopause, you should contact the doctor if you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding. Do not stop using any medications without talking to a doctor.
TopiramateOrphenadrine (citrate)
Severe
How does the drug interact with Topamac 50 mg Tablet:
Combining Orphenadrine with Topamac 50 mg Tablet can increase the risk of overheating and reduced sweating.

How to manage the interaction:
Although there is a possible interaction between Orphenadrine (citrate) and Topamac 50 mg Tablet, you can take these medicines together if prescribed by your doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a balanced diet that consists of good fats, proteins, carbohydrates, vegetables, and fruit which helps the body and brain to work properly and keep a person healthy and energetic.
  • Fatigue is one of the primary reasons that trigger seizures in the body, so sleeping properly can help in relaxing the brain.
  • One should avoid the consumption of alcohol as it can trigger seizures in patients. Even one or two glasses can trigger epilepsy and worsen the side effects of Topamac 50 mg Tablet .
  • Keep yourself happy and avoid taking emotional stress as stress causes seizures. Persons who maintain healthy stress levels have reported that they have responded well to the medicine.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • METFORMIN
  • GLIBENCLAMIDE
  • PIOGLITAZONE
  • VENLAFAXINE
  • AMITRIPTYLINE
  • DILTIAZEM
  • HYDROCHLOROTHIAZIDE
  • PROPRANOLOL
  • RISPERIDONE

Disease/Condition Glossary

Epilepsy: It is a neurological disorder in which brain activity becomes abnormal characterized by intense electrical bursts in the brain (seizures). When these bursts happen in one part of the brain it is called a partial seizure while if these bursts occur in the complete brain it is called a generalized seizure. Sometimes, a person starts experiencing the symptoms before starting of seizure that includes a sudden feeling of fear, dizziness, changes in vision, shakiness in arms and legs, and headache. While the symptoms that occur during a seizure include losing consciousness, characterized by confusion, uncontrollable muscle spasms, falling, biting tongue, sudden, rapid eye movements, unusual noises, such as grunting, sudden mood changes, etc.

Migraine: It is a mild to severe headache that starts as a dull ache in the region around the eye. It usually lasts a few hours up to several days and gets worst with the movement. The possible warning signs that can start before the occurrence of migraine include visual changes, unusual tiredness, tingling in an arm or leg. A person facing migraine may also face mild to severe pain in the head, pulsing, throbbing pain in the head, sensitivity to sound and light, vomiting, and Nausea.

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