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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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Composition :

TOPOTECAN-2.5MG

Manufacturer/Marketer :

Unitech Health Care Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Return Policy :

Not Returnable

About Topotec 2.5Mg Inj

Topotec 2.5Mg Inj belongs to a group of medicines called 'anti-cancer/anti-neoplastic agents', used to treat ovarian and small cell lung cancer. On the other hand, it may use to treat advanced cervical cancer if surgery or radiotherapy treatment is not possible. It may sometimes be used to treat other cancers. Ovarian cancer begins in the ovaries (a pair of female reproductive glands in which the ova, or eggs, are formed). Small-cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues.

Topotec 2.5Mg Inj contains 'Topotecan'. It works by penetrating into the cell wall and binding to the cell's DNA, stopping it from naturally dividing and functioning, ultimately destroying it. These medicines target cancer cells because they often affect rapidly dividing cells.

The amount of medicine that you will receive depends on many factors, including your height and weight, your general health or other health problems, and the type of cancer or condition being treated. Your doctor will determine your dose and schedule. Topotec 2.5Mg Inj is prescribed by a doctor experienced in the use of medications to treat cancer. You may sometimes experience nausea, diarrhoea, vomiting, thrombocytopenia (a low platelet count), peripheral neuropathy (nerves malfunction), nephrotoxicity at high doses, and electrolyte disturbances. Most of these side effects of Topotec 2.5Mg Inj do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking Topotec 2.5Mg Inj for as long as your doctor has prescribed. Do not stop using the Topotec 2.5Mg Inj midway. Talk to your doctor before taking Topotec 2.5Mg Inj if you have severe allergic reactions to Topotec 2.5Mg Inj or other medicines or suffer from severe lung problems, Infections, renal dysfunction, hepatic disorders and blood cell counts are too low. Avoid taking Topotec 2.5Mg Inj if you are pregnant or breastfeeding because this Topotec 2.5Mg Inj can cause harmful effects on the unborn baby. Both women and men using this Topotec 2.5Mg Inj should use birth control to avoid pregnancy.

Uses of Topotec 2.5Mg Inj

Ovarian cancer and Small cell lung cancer

Directions for Use

Topotec 2.5Mg Inj will be administered by a qualified healthcare professional. Hence, do not self-administer.

Key Benefits

Topotec 2.5Mg Inj contains 'Topotecan', which belongs to a group of anti-cancer medicines used to treat ovarian cancer and small cell lung cancer. It works by damaging the genetic material (DNA) of the cancer cells, which stops their growth and multiplication. It can be used alone or together with other chemotherapy drugs depending on the type of cancer you have.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Topotec 2.5Mg Inj will be administered by a healthcare professional. To treat your condition effectually, continue taking Topotec 2.5Mg Inj for as long as your doctor has prescribed. Do not stop Topotec 2.5Mg Inj midway. Talk to your doctor before taking Topotec 2.5Mg Inj if you have severe allergic reactions to Topotec 2.5Mg Inj or other medicines or suffer from severe lung problems, Infections, renal dysfunction, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), hepatic disorders. Topotec 2.5Mg Inj should not be employed in patients with severe bone marrow depression or significant bleeding. Avoid taking Topotec 2.5Mg Inj if you are pregnant or breastfeeding because this Topotec 2.5Mg Inj can cause harmful effects on the unborn baby. Both women and men using this Topotec 2.5Mg Inj should use birth control to avoid pregnancy. Peripheral blood counts should be frequently monitored during Topotec 2.5Mg Inj treatment and appropriate until recovery is achieved. Do not receive any kind of immunization or vaccination without your doctor's approval while taking the Topotec 2.5Mg Inj.

Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Side Effects of Topotec 2.5Mg Inj

  • Feeling generally weak and tired (temporary anaemia)
  • Low white blood cell count (neutropenia)
  • Unusual bruising or bleeding
  • Weight loss and loss of appetite (anorexia)
  • Tiredness
  • Weakness
  • Feeling sick (nausea)
  • Being sick (vomiting)
  • Diarrhoea
  • Stomach pain
  • Constipation
  • Inflammation and ulcers of the mouth, tongue or gums
  • Inflammation and ulcers of the mouth, tongue or gums
  • High body temperature (fever)
  • Hair loss
  • Headache
  • Allergic or hypersensitivity reactions (rash)
  • Yellow skin
  • Itching sensation
  • Feeling unwell (malaise)
  • Deficiency of the blood (pancytopenia)

Habit Forming

No

Therapeutic Class

[ANTINEOPLASTIC]

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FAQs

Drug-Drug Interactions Checker List

  • PACLITAXEL
  • BEVACIZUMAB

Special Advise

  • Topotec 2.5Mg Inj should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Topotec 2.5Mg Inj.
  • Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Peripheral blood counts should be frequently monitored during Topotec 2.5Mg Inj treatment and, when appropriate until recovery is achieved.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Topotec 2.5Mg Inj may make your skin sensitive to sunlight.

Disease/Condition Glossary

Cancer: Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. Cancer sometimes begins in one body part before spreading to other areas.

Ovarian cancer: Ovarian cancer is a type of cancer that begins in the ovaries (one of a pair of female reproductive glands in which the ova, or eggs, are formed).

Small cell lung cancer: Small cell lung cancer is a disease in which malignant (cancer) cells form in the lung tissues.

Have a query?

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Alcohol

Safe if prescribed

Avoid alcohol consumption while on treatment with Topotec 2.5Mg Inj.

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Pregnancy

Consult your doctor

Topotec 2.5Mg Inj should not be used during pregnancy because it can harm your fetus (newborn baby). Both women of childbearing potential and men must use an effective contraception method while taking Topotec 2.5Mg Inj and at least for six months later treatment. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Breast Feeding

Consult your doctor

Topotec 2.5Mg Inj should not be used during breastfeeding as it passes into the breastmilk and may harm your baby. Hence, if you are breastfeeding, inform your doctor before receiving this medicine.

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Driving

Safe if prescribed

Topotec 2.5Mg Inj may affect your reactions and your ability to drive. Note: Possible side effects of chemotherapy with Topotec 2.5Mg Inj may occur, such as nausea and vomiting. If you are affected by these side effects, do not drive and/or operate machines that require your alertness.

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Liver

Consult your doctor

If you have had a history or evidence of liver impairment, please inform your doctor before taking the Topotec 2.5Mg Inj. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Kidney

Consult your doctor

If you have had a history or evidence of kidney diseases, please inform your doctor before taking the Topotec 2.5Mg Inj. Your doctor may adjust the dose or prescribe a suitable alternative if necessary based on your condition.

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Children

Safe if prescribed

The safety and effectiveness of Topotec 2.5Mg Inj in pediatric patients have not been established. Please consult your doctor. Your doctor will weigh the benefits and any potential risks before prescribing this medicine.

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