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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Torrent Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Torvate Chrono 300 Tablet

Torvate Chrono 300 Tablet belongs to a group of medicines called 'anticonvulsants' or 'anti-epileptics' primarily used to treat epilepsy/seizures/fits. Additionally, Torvate Chrono 300 Tablet is also used to treat mood disorders and migraine. Epilepsy is a sudden rush of electricity in the brain. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulse that affect an individual's consciousness, movements or sensations.
­ 
Torvate Chrono 300 Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Torvate Chrono 300 Tablet works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Torvate Chrono 300 Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.
 
You are advised to take Torvate Chrono 300 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Talk to your doctor if you experience these side-effects persistently.
 
Do not take Torvate Chrono 300 Tablet if you are pregnant, as it could cause serious congenital disabilities. If you are of child-bearing age, use effective contraception while taking Torvate Chrono 300 Tablet . Consult your doctor before taking Torvate Chrono 300 Tablet if you are breastfeeding. Torvate Chrono 300 Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Torvate Chrono 300 Tablet as it could lead to an increased risk of seizures. Care should be taken while giving Torvate Chrono 300 Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Uses of Torvate Chrono 300 Tablet

Epilepsy, Mood disorder, Migraine

Directions for Use

Take Torvate Chrono 300 Tablet with or 1hour prior food. Swallow Torvate Chrono 300 Tablet a whole with a glass of water, do not chew, or break it.

Medicinal Benefits

Torvate Chrono 300 Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Torvate Chrono 300 Tablet is used to treat epilepsy/seizures/fits, mood disorders and to prevent migraine headaches. Torvate Chrono 300 Tablet decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Torvate Chrono 300 Tablet is used to treat certain forms of epilepsy such as petit mal epilepsy (short-term unconsciousness due to disorder in the brain), myoclonic seizures (sudden muscle contractions) and grand mal epilepsy (severe muscle contractions which lead to unconsciousness). Torvate Chrono 300 Tablet may also be used to treat epilepsy which does not sufficiently respond to other anticonvulsant drugs, such as epilepsy which is not associated with movements and epilepsy with symptoms affecting perception and deliberate movements. Torvate Chrono 300 Tablet is used to treat both partial seizures (affects only a part of the brain) and generalised seizures (affects the entire brain).

Storage

Store in a cool and dry place away from sunlight

Side Effects of Torvate Chrono 300 Tablet

  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Sleepiness
  • Drowsiness
  • Impaired coordination
  • Apathy (lack of interest)
  • Hair loss
  • Irregular periods
  • Weight gain

Drug Warnings

Do not take Torvate Chrono 300 Tablet if you are allergic to any of its contents, if you have/ had liver problems, porphyria (blood disorder) or if you are susceptible to bleeding. Inform your doctor if you have inflammation-like diseases, bone marrow damage or kidney problems. Talk to your doctor if you experience weakness, loss of appetite, lack of interest, recurrence or worsening of seizures, prolonged bleeding or abdominal pain while taking Torvate Chrono 300 Tablet . Consult your doctor immediately if you experience suicidal tendencies while taking Torvate Chrono 300 Tablet . Please do not stop taking Torvate Chrono 300 Tablet without consulting your doctor to avoid the worsening of seizures. Do not take Torvate Chrono 300 Tablet if you are pregnant, as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Torvate Chrono 300 Tablet . Consult your doctor before taking Torvate Chrono 300 Tablet if you are breastfeeding. Torvate Chrono 300 Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Torvate Chrono 300 Tablet as it could lead to increased risk of seizures. Care should be taken while giving Torvate Chrono 300 Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
Sodium ValproateSodium phenylbutyrate
Critical

Drug-Drug Interactions

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DivalproexGlycerol phenylbutyrate
Critical
How does the drug interact with Torvate Chrono 300 Tablet:
Coadministration of Glycerol phenylbutyrate and Torvate Chrono 300 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Glycerol phenylbutyrate and Torvate Chrono 300 Tablet together is generally avoided as it can lead to an interaction, it can be taken when your doctor advises. If you experience any symptoms like sudden dizziness, headaches, vomiting, and visual disturbances, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Torvate Chrono 300 Tablet:
Combining Sodium phenylbutyrate and Torvate Chrono 300 Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Torvate Chrono 300 Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
DivalproexVorinostat
Severe
How does the drug interact with Torvate Chrono 300 Tablet:
Coadministration of Torvate Chrono 300 Tablet and Vorinostat can increase the risk of bleeding.

How to manage the interaction:
Although there is a possible interaction between Torvate Chrono 300 Tablet and Vorinostat, you can take these medicines together if prescribed by your doctor. If you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting your doctor.
DivalproexBuprenorphine
Severe
How does the drug interact with Torvate Chrono 300 Tablet:
Co-administration of buprenorphine with Torvate Chrono 300 Tablet may increase the risk of developing side effects.

How to manage the interaction:
Co-administration of Buprenorphine with Torvate Chrono 300 Tablet can result in an interaction, it can be taken when a doctor has advised it. However, if you experience shortness of breath, irregular heart rhythms, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
DivalproexBexarotene
Severe
How does the drug interact with Torvate Chrono 300 Tablet:
Co-administration of Torvate Chrono 300 Tablet and Bexarotene can increase the risk of pancreatitis (inflammation of the pancreas).

How to manage the interaction:
Co-administration of Torvate Chrono 300 Tablet and Bexarotene can lead to an interaction, but it can be taken when advised by your doctor. However, if you experience any symptoms like nausea, vomiting, or stomach cramps, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexMipomersen
Severe
How does the drug interact with Torvate Chrono 300 Tablet:
Co-administration of Torvate Chrono 300 Tablet and mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Torvate Chrono 300 Tablet and mipomersen can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any symptoms like fever, chills, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, and yellowing of the skin or eyes, consult the doctor immediately. Avoid alcohol consumption, and Do not stop using any medications without a doctor's advice.
DivalproexLomitapide
Severe
How does the drug interact with Torvate Chrono 300 Tablet:
Co-administration of Torvate Chrono 300 Tablet and Lomitapide can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Torvate Chrono 300 Tablet and lomitapide can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like fever, joint pain, unusual bleeding, weakness, nausea, vomiting, stomach pain, dark urine, pale stools, or yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without the doctor's advice.
DivalproexKetamine
Severe
How does the drug interact with Torvate Chrono 300 Tablet:
Co-administration of Torvate Chrono 300 Tablet and Ketamine can increase the risk of side effects.

How to manage the interaction:
Co-administration of Torvate Chrono 300 Tablet and Ketamine can lead to an interaction, it can be taken if advised by your doctor. If you have any symptoms such as dizziness, drowsiness, shortness of breath, or impairment in thinking and motor coordination, make sure to contact your doctor right away. Do not stop using any medications without a doctor's advice.
DivalproexKetoconazole
Severe
How does the drug interact with Torvate Chrono 300 Tablet:
Coadministration of Ketoconazole and Torvate Chrono 300 Tablet may increase the risk of liver damage.

How to manage the interaction:
Although taking Ketoconazole and Torvate Chrono 300 Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you have any of the following symptoms: fever, chills, joint pain, fatigue, nausea, vomiting, stomach pain, dark urine, and yellowing of the skin or eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
DivalproexDoripenem
Severe
How does the drug interact with Torvate Chrono 300 Tablet:
Co-administration of Torvate Chrono 300 Tablet and Doripenem can reduce the blood levels of Torvate Chrono 300 Tablet sodium and increase the risk of developing seizures.

How to manage the interaction:
Co-administration of Torvate Chrono 300 Tablet with Doripenem can possibly result in an interaction, it can be taken when your doctor has advised it. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan; this helps those around you know what to do.
  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Torvate Chrono 300 Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Torvate Chrono 300 Tablet decreases the excessive and abnormal nerve activity in the brain. Torvate Chrono 300 Tablet increases the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect. Thereby helps in controlling seizures.

Do not discontinue Torvate Chrono 300 Tablet without consulting your doctor. To treat your condition effectually, continue taking Torvate Chrono 300 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Torvate Chrono 300 Tablet ; your doctor will reduce the dose gradually to avoid worsening of seizures.

Torvate Chrono 300 Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising.

Torvate Chrono 300 Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Torvate Chrono 300 Tablet may increase the effect of aspirin when taken together. Please consult your doctor before taking Torvate Chrono 300 Tablet with aspirin to avoid unpleasant side-effects. Torvate Chrono 300 Tablet and aspirin should not be given together to children below 3 years as it could lead to liver intoxication.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • LAMOTRIGINE
  • FELBAMATE
  • ZIDOVUDINE
  • AMITRIPTYLINE
  • SERTRALINE
  • QUETIAPINE
  • OLANZAPINE
  • RISPERIDONE
  • LEVONORGESTREL
  • MEFLOQUINE
  • CIMETIDINE
  • IMIPENEM
  • MEROPENEM
  • ERYTHROMYCIN
  • CHOLESTYRAMINE
  • CLONAZEPAM
  • DIAZEPAM

Special Advise

  • Regular monitoring of blood count is advised while taking Torvate Chrono 300 Tablet as it may cause spontaneous bleeding or bruising.
  • Inform your doctor that you are taking Torvate Chrono 300 Tablet if you are due to have any surgery or dental intervention.
  • Consult your doctor if you experience irregular periods while taking Torvate Chrono 300 Tablet .
  • If you are of child-bearing age, use effective contraception while taking Torvate Chrono 300 Tablet .

Disease/Condition Glossary

Epilepsy/Seizures: Seizures, also known as fits or convulsions, is a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. The possible causes of epilepsy include traumatic brain injury, scarring on the brain after a brain injury, high fever, stroke, vascular diseases, lack of oxygen to the brain, brain tumours, and genetic disorders. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness.

Mood disorder: It is a mental health disorder which mainly affects a person's emotional state. A mood disorder is associated with episodes of mood swings ranging from manic highs to depressive lows. 

Migraine: Migraine is a neurological condition which is characterised by an intense, debilitating headache. Hormonal changes, stress, lack or excess of sleep, bright lights, loud sounds, certain foods and drinks can trigger migraine headaches. Symptoms of migraine include throbbing pain in one particular area with varying intensity, nausea, vomiting, numbness or tingling sensation, difficulty speaking, and sensitivity to sound and light. 

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