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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

Sanofi India Ltd

Consume Type :

PARENTERAL

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Not Returnable

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About Toujeo 300U/ml Cartridge 3x

Toujeo 300U/ml Cartridge 3x is a long-acting insulin that contains insulin glargine. This is a modified insulin, very similar to human insulin. Human insulin is the name which describes synthetic (human-made) insulin, which is laboratory grown to mimic the insulin in humans. Toujeo 300U/ml Cartridge 3x is used to treat diabetes mellitus in adults, adolescents and children aged two years and above. Diabetes mellitus is a disease where your body does not produce enough insulin to control the level of blood sugar. Toujeo 300U/ml Cartridge 3x has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to work uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. Treatment with Toujeo 300U/ml Cartridge 3x helps to prevent complications from your diabetes. Do not use Toujeo 300U/ml Cartridge 3x to treat diabetic ketoacidosis (too much acid in the blood).

Toujeo 300U/ml Cartridge 3x is a long-acting insulin that works by ensuring consistent sugar control. Hence, it helps lower blood sugar levels throughout the day. Based on your lifestyle, the results of your blood sugar (glucose) tests, and your previous insulin usage. Your doctor will advise you how much Toujeo 300U/ml Cartridge 3x per day you will need and when you need to take it.

Sometimes, you may experience injection site reactions such as lumps under the skin. The injection site should be rotated to prevent skin changes such as lumps under the skin. You may also experience symptoms of hypoglycaemia (low blood sugar) such as sweating, clammy skin, anxiety, fast heartbeat. Most of these side effects of Toujeo 300U/ml Cartridge 3x do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Toujeo 300U/ml Cartridge 3x of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Toujeo 300U/ml Cartridge 3x if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Toujeo 300U/ml Cartridge 3x, you should take a healthy diet, exercise regularly, and maintain weight as your doctor advises. Toujeo 300U/ml Cartridge 3x is a cold chain medicine, so it must be stored in the refrigerator between 2-8 degrees Celsius; otherwise, its efficiency might get lost. Do not store it in the freezer of the fridge.

Uses of Toujeo 300U/ml Cartridge 3x

Diabetes (Type 1 diabetes mellitus, Type 2 diabetes mellitus)

Directions for Use

Toujeo 300U/ml Cartridge 3x is injected under the skin (subcutaneously). Do NOT inject Toujeo 300U/ml Cartridge 3x in a vein. You need one injection of Toujeo 300U/ml Cartridge 3x every day, at the same time of the day. If you are not well trained to self-administer Toujeo 300U/ml Cartridge 3x, ask healthcare professional to administer it.Procedure for self-injecting insulin:•You should wash your hand first before injecting insulin.•Then roll the insulin bottle and wipe the bottle top.•Now pull the plunger of the syringe down to an appropriate number of units your doctor has prescribed.•Push the needle into the bottle and push the syringe plunger down.•Now once again pull the plunger down to an appropriate number of units as prescribed by the doctor.•Pick the injection site and wipe it with an alcohol swab. Now, pinch up the skin and push the needle into the skin and then push the plunger in.•The needle should be kept under the skin for at least 6 seconds to make sure the entire dose is injected.•After injecting the insulin pull out the needle and dispose of the syringe safely. And then you can have a meal or snack.

Medicinal Benefits

Toujeo 300U/ml Cartridge 3x has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to work uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours. This insulin causes body tissues to absorb glucose from the blood and decreases glucose production by the liver. Toujeo 300U/ml Cartridge 3x helps in improving the glycaemic control, which in turn reduces the risk of progression of complications of diabetes like damage to the retina (retinopathy), impairment of kidney (nephropathy), injury of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer and others. Besides this, Toujeo 300U/ml Cartridge 3x can be safely prescribed to pregnant and lactating mothers.

Storage

Store in a cool and dry place away from sunlight
Side effects of Toujeo 300U/ml Cartridge 3x1.5 ml
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Get ample rest; this helps your stomach to settle.
  • Eat soft and easy-to-digest foods like white rice, bananas, crackers and apple sauce.
  • Include probiotics-rich food like yoghurt, kefir, or miso, as they help maintain gut functioning.
  • Wash your hands properly before preparing/eating food and after using the toilet.
  • Drink water, broth or diluted fruit juice to replace electrolytes and lost fluids.
  • Avoid caffeine, alcohol, high-fat, fried and fast foods, as well as sweetened beverages.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.

Drug Warnings

Toujeo 300U/ml Cartridge 3x is for subcutaneous (under the skin) use only and should never be administered intravenously (IV) or in the veins. If you are changing the brand of insulin or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure were reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first symptoms of hyperglycaemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Toujeo 300U/ml Cartridge 3x may decrease the potassium level, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma and even death. Do not take Toujeo 300U/ml Cartridge 3x if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Toujeo 300U/ml Cartridge 3x1.5 ml:
Taking Toujeo 300U/ml Cartridge 3x1.5 ml with Moxifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Moxifloxacin and Toujeo 300U/ml Cartridge 3x1.5 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience headache, dizziness, and rapid heartbeat, increased thirst, and increased urination. Do not stop using any medications without talking to a doctor.
Severe
How does the drug interact with Toujeo 300U/ml Cartridge 3x1.5 ml:
Taking Toujeo 300U/ml Cartridge 3x1.5 ml with cinoxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking cinoxacin and Toujeo 300U/ml Cartridge 3x1.5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Severe
How does the drug interact with Toujeo 300U/ml Cartridge 3x1.5 ml:
Taking Toujeo 300U/ml Cartridge 3x1.5 ml with enoxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking enoxacin and Toujeo 300U/ml Cartridge 3x1.5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Toujeo 300U/ml Cartridge 3x1.5 ml:
Co-administration of Ofloxacin and Toujeo 300U/ml Cartridge 3x1.5 ml can sometimes have an effect on blood glucose levels.

How to manage the interaction:
Although combining Ofloxacin and Toujeo 300U/ml Cartridge 3x1.5 ml can lead to an interaction, they can be taken on a doctor's advice. If you experience any symptoms of hypoglycemia (headache, dizziness, sleepiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitation, and rapid heartbeat) or hyperglycemia (increased thirst, hunger, and urination), consult a doctor. Keep an eye on your blood glucose levels. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Toujeo 300U/ml Cartridge 3x1.5 ml:
Taking Toujeo 300U/ml Cartridge 3x1.5 ml with gatifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Gatifloxacin and Toujeo 300U/ml Cartridge 3x1.5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin glargineGrepafloxacin
Severe
How does the drug interact with Toujeo 300U/ml Cartridge 3x1.5 ml:
Taking Toujeo 300U/ml Cartridge 3x1.5 ml with grepafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Grepafloxacin and Toujeo 300U/ml Cartridge 3x1.5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin glargineTrovafloxacin
Severe
How does the drug interact with Toujeo 300U/ml Cartridge 3x1.5 ml:
Taking Toujeo 300U/ml Cartridge 3x1.5 ml with Trovafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Trovafloxacin and Toujeo 300U/ml Cartridge 3x1.5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Toujeo 300U/ml Cartridge 3x1.5 ml:
Taking Toujeo 300U/ml Cartridge 3x1.5 ml with Gemifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Gemifloxacin and Toujeo 300U/ml Cartridge 3x1.5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Toujeo 300U/ml Cartridge 3x1.5 ml:
Taking Toujeo 300U/ml Cartridge 3x1.5 ml with sparfloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar) less frequently.

How to manage the interaction:
Although taking Sparfloxacin and Toujeo 300U/ml Cartridge 3x1.5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitations, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Toujeo 300U/ml Cartridge 3x1.5 ml:
Blood glucose levels can be affected by levofloxacin when taken with Toujeo 300U/ml Cartridge 3x1.5 ml. It may cause hyperglycemia (high blood glucose) and, less commonly, hypoglycemia (low blood glucose).

How to manage the interaction:
There could be a possible interaction between Toujeo 300U/ml Cartridge 3x1.5 ml and Levofloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercise may lower your body’s need for insulin during and sometimes after physical activity.
  • Exercise may also speed up the effect of an insulin dose, especially if the activity involves the area of the injection site (for example, the leg should not be used for injection just before running).
  • Discuss with your doctor how to adjust your insulin regimen to accommodate exercise. 
  • Avoid eating sugar food and prefer food cooked food low in calories.
  • When travelling across more than two time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

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ANTIDIABETICS

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Toujeo 300U/ml Cartridge 3x should not be given into the veins or intravenously (IV) route. It should be only administered in the subcutaneous region below the skin. Abdomen regions (stomach) is the best site for the injecting Toujeo 300U/ml Cartridge 3x. However, you can also inject Toujeo 300U/ml Cartridge 3x in the upper arm, or thigh region.

Toujeo 300U/ml Cartridge 3x can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Toujeo 300U/ml Cartridge 3x can be given to you or not depending on your present condition. Toujeo 300U/ml Cartridge 3x should be avoided in patients who are allergic to Toujeo 300U/ml Cartridge 3x or other forms of insulin. It should be avoided in patients suffering from low potassium level (hypokalemia), moderate to severe kidney disease or liver disease. Inform the doctor if you are pregnant or breastfeeding.

The active substance is insulin glargine. Each ml of the solution contains 100 units of insulin glargine (equivalent to 3.64 mg).

Toujeo 300U/ml Cartridge 3x has a long and steady blood-sugar-lowering action. Long-acting insulin takes about 2 hours to start acting and is designed to act uniformly so that there is no peak activity as such. The duration of long-acting insulin is up to 24 hours.

Toujeo 300U/ml Cartridge 3x is a cold chain medicine which has to be stored 2-8 degree Celsius only else its efficiency of reducing blood glucose level declines. Do not keep inside the freezer.

Type-2 diabetes generally does not affect healthy children and teens, but it may affect children who are obese, which is also known as Childhood Obesity.

Toujeo 300U/ml Cartridge 3x is generally safe to take for a long time. In fact, it works best if you take it for many months or even years.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • SITAGLIPTIN
  • PREGABALIN
  • METOPROLOL
  • LEVOTHYROXINE SODIUM
  • CLONIDINE
  • LITHIUM
  • FLUOXETINE
  • RIFAMPICIN+ISONIAZID
  • CLOZAPINE
  • OLANZAPINE
  • FENOFIBRATE
  • EPINEPHRINE
  • SALBUTAMOL
  • ESTROGEN
  • PROGESTERONE

Special Advise

Change (rotate) your injection sites within the area you chose with each dose to reduce your risk of getting lipodystrophy (pitted or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites. Do not use the same spot for each injection or injection where the skin is pitted, thickened, lumpy, tender, bruised, scaly, hard, scarred or damaged.

Disease/Condition Glossary

Diabetes: Diabetes is a chronic or lifelong disease that prevents the body from utilizing insulin properly. Insulin is the hormone that controls sugar levels in the blood. Diabetes is a condition in which blood glucose levels are above normal. It is of two types, namely: type-1 and type-2 diabetes. Type-1 diabetes is a condition in which the pancreas produces little or no insulin. Type-2 diabetes affects the way body processes the sugar. Symptoms of diabetes include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.

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