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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About TRAMADIN PLUS TABLET

TRAMADIN PLUS TABLET belongs to a class of drugs called analgesics (pain killers) primarily used to treat moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body).

TRAMADIN PLUS TABLET is a combination of two drugs, namely: Tramadol (opioid analgesic) and Acetaminophen (analgesic and antipyretic). Tramadol works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.

Take TRAMADIN PLUS TABLET as prescribed by your doctor. You are advised to take TRAMADIN PLUS TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience drowsiness, nausea, dizziness, headache, vomiting, dry mouth, constipation, excessive sweating, shaking, confusion or mood changes. Most of these side effects of TRAMADIN PLUS TABLET do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to TRAMADIN PLUS TABLET or any other medicines, please tell your doctor. TRAMADIN PLUS TABLET is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking TRAMADIN PLUS TABLET if you are pregnant as it may cause withdrawal symptoms in the newborn baby. TRAMADIN PLUS TABLET may be excreted in human milk. Please consult a doctor if you are breastfeeding. It is an offence to drive if TRAMADIN PLUS TABLET affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking TRAMADIN PLUS TABLET. Avoid alcohol consumption with TRAMADIN PLUS TABLET as it may increase drowsiness.

Uses of TRAMADIN PLUS TABLET

Moderate to severe pain

Directions for Use

Take TRAMADIN PLUS TABLET with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

TRAMADIN PLUS TABLET is a combination of two drugs: Tramadol and Acetaminophen to treat moderate to severe pain. Tramadol mimics the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby inhibits the transmission of pain signals from nerves to brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.

Storage

Keep TRAMADIN PLUS TABLET out of reach and sight of children.

Drug Warnings

If you are allergic to TRAMADIN PLUS TABLET or any other medicines, please tell your doctor. TRAMADIN PLUS TABLET is not recommended for children below 12 years of age, as the safety and effectiveness were not established. Avoid taking TRAMADIN PLUS TABLET if you are pregnant as it may cause withdrawal symptoms in the newborn baby. TRAMADIN PLUS TABLET may be excreted in human milk. Please consult a doctor if you are breastfeeding. If you have fits, asthma, severe lung problems, drug dependence,  liver or kidney problems, inform your doctor before taking TRAMADIN PLUS TABLET. It is an offence to drive if TRAMADIN PLUS TABLET affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking TRAMADIN PLUS TABLET. Avoid alcohol consumption with TRAMADIN PLUS TABLET as it may increase drowsiness. Do not take TRAMADIN PLUS TABLET if you are taking pain relievers, sleeping pills, or taking medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. Inform your doctor immediately if you experience any sleep-related breathing problems such as sleep apnoea (breathing stops and starts repeatedly) while taking TRAMADIN PLUS TABLET.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Tramadin Plus Tablet:
Co-administration of Ziprasidone with Tramadin Plus Tablet can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Tramadin Plus Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Tramadin Plus Tablet:
Taking rasagiline with Tramadin Plus Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tramadin Plus Tablet with Rasagiline is not recommended, as it can lead to an interaction, but can be taken if advised by your doctor. However, if you experience any symptoms like severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Tramadin Plus Tablet:
Taking Safinamide with Tramadin Plus Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Safinamide with Tramadin Plus Tablet is not recommended as it can possibly result in an interaction, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and loose stools. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Tramadin Plus Tablet:
Co-administration of Linezolid with Tramadin Plus Tablet can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Linezolid with Tramadin Plus Tablet is not recommended, consult a doctor before taking it. Consult a doctor if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not stop using any medications without talking to a doctor.
TramadolPhenelzine
Critical
How does the drug interact with Tramadin Plus Tablet:
Combining Phenelzine with Tramadin Plus Tablet can increase the risk of serotonin syndrome and seizures.

How to manage the interaction:
Taking Tramadin Plus Tablet with Phenelzine is not recommended, please consult your doctor before taking it.
How does the drug interact with Tramadin Plus Tablet:
Combining Tranylcypromine with Tramadin Plus Tablet can increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Tranylcypromine with Tramadin Plus Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience confusion, hallucination(seeing and hearing things that do not exist), fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting your doctor.
TramadolAlvimopan
Critical
How does the drug interact with Tramadin Plus Tablet:
Co-administration of Tramadin Plus Tablet with Alvimopan can make the side effects worse or more dangerous.

How to manage the interaction:
Taking Alvimopan with Tramadin Plus Tablet is not recommended, please consult your doctor before taking it.
ParacetamolLomitapide
Severe
How does the drug interact with Tramadin Plus Tablet:
Co-administration of Lomitapide and Tramadin Plus Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Tramadin Plus Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolMipomersen
Severe
How does the drug interact with Tramadin Plus Tablet:
Co-administration of Mipomersen with Tramadin Plus Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Tramadin Plus Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Tramadin Plus Tablet:
Co-administration of Tramadin Plus Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Tramadin Plus Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercises such as swimming or walking.
  • Drink plenty of water while taking TRAMADIN PLUS TABLET to avoid dry mouth.
  • Maintain a fibre rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking TRAMADIN PLUS TABLET.
  • Avoid consumption of alcohol and quit smoking.

Side Effects of TRAMADIN PLUS TABLET

  • Drowsiness
  • Nausea
  • Dizziness
  • Headache
  • Vomiting
  • Dry mouth
  • Constipation
  • Excessive sweating
  • Shaking
  • Confusion
  • Mood changes

Habit Forming

Yes

Therapeutic Class

ANALGESICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

TRAMADIN PLUS TABLET contains Tramadol and Acetaminophen. Tramadol is an opioid analgesic that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibits the transmission of pain signals from nerves to the brain. Also, it improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Acetaminophen is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever.

TRAMADIN PLUS TABLET may cause dry mouth as a common side effect. It is not necessary for everyone taking TRAMADIN PLUS TABLET to experience this side effect. However, drink plenty of water, suck on sugar candy or chew sugar-free gum to prevent such side effects while taking TRAMADIN PLUS TABLET. If the condition worsens or persist, please consult a doctor.

TRAMADIN PLUS TABLET should be used with caution in patients suffering from fits as it may worsen the condition. Therefore, it is recommended to inform your doctor if you ever had fits before taking TRAMADIN PLUS TABLET.

No, you are not recommended to take TRAMADIN PLUS TABLET with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with TRAMADIN PLUS TABLET may increase the risk of fits. However, please consult a doctor before taking TRAMADIN PLUS TABLET with other medicines.

TRAMADIN PLUS TABLET may cause addiction, especially if taken for a prolonged time. Therefore, TRAMADIN PLUS TABLET should be given only for a short duration under strict medical supervision, particularly to patients who are susceptible to drug abuse. Take TRAMADIN PLUS TABLET only as a doctor advised as overuse or misuse of TRAMADIN PLUS TABLET can lead to overdose and cause severe adverse effects.

You are not recommended to take TRAMADIN PLUS TABLET with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

TRAMADIN PLUS TABLET may cause withdrawal symptoms such as difficulty sleeping, anxiety, nervousness, shaking, stomach or bowel disorders, or making you overactive when you stop taking TRAMADIN PLUS TABLET suddenly. Therefore, if you experience any difficulty while taking TRAMADIN PLUS TABLET, do not stop taking suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.

Drug-Drug Interactions Checker List

  • CARBAMAZEPINE
  • PREGABALIN
  • PENTAZOCIN
  • BUPRENORPHINE
  • MORPHINE
  • CODEINE
  • BACLOFEN
  • WARFARIN
  • PHENPROCOUMON
  • ONDANSETRON
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • ZOLPIDEM
  • CELECOXIB
  • DULOXETINE
  • ESCITALOPRAM
  • ALPRAZOLAM
  • NALBUPHINE

Special Advise

  • Patients with severe liver or kidney insufficiency should avoid taking TRAMADIN PLUS TABLET.
  • Do not give TRAMADIN PLUS TABLET to others. Use TRAMADIN PLUS TABLET only when prescribed by a doctor and avoid frequent or high doses as it may cause addiction.
  • Please do not stop taking TRAMADIN PLUS TABLET suddenly as it may cause withdrawal symptoms such as difficulty in sleeping, anxiety, nervousness, shaking, stomach or bowel disorders or make you overactive. Therefore, take TRAMADIN PLUS TABLET for as long as your doctor has prescribed it.

Disease/Condition Glossary

Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body). Pain is highly subjective as some people have a high tolerance for pain while others have a low tolerance. Although pain is inconvenient and unpleasant, it hints about causes when something is wrong in the body. Pain may be caused due to cramps, headache, bone fractures, stomach pain, arthritis (swelling of one or more joints), muscle strain or overuse, cuts, flu, irritable bowel syndrome (an intestinal disorder causing stomach pain, diarrhoea or constipation) and fibromyalgia (muscle pain with stiffness and tenderness).

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol with TRAMADIN PLUS TABLET as it may cause drowsiness.

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Pregnancy

Unsafe

TRAMADIN PLUS TABLET is not recommended for pregnant women as it may cause withdrawal symptoms in the newborn baby. However, please consult your doctor if you are pregnant.

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Breast Feeding

Caution

TRAMADIN PLUS TABLET may be excreted in breast milk and cause adverse effects in the baby. However, please consult a doctor if you are breastfeeding.

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Driving

Unsafe

TRAMADIN PLUS TABLET may cause dizziness or drowsiness in some people. It is an offence to drive if TRAMADIN PLUS TABLET affects you. Therefore, avoid driving if you feel drowsy or dizzy after taking TRAMADIN PLUS TABLET.

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Liver

Caution

Take TRAMADIN PLUS TABLET with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking TRAMADIN PLUS TABLET if you have severe liver insufficiency.

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Kidney

Caution

Take TRAMADIN PLUS TABLET with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking TRAMADIN PLUS TABLET if you have severe kidney insufficiency.

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Children

Unsafe

TRAMADIN PLUS TABLET is not recommended for children below 12 years of age, as the safety and effectiveness were not established.

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