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Trental 400 Tablet 15's

Trental 400 Tablet 15's

Consult Doctor
Prescription drug
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Manufacturer/Marketer

Sanofi India Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Trental 400 Tablet 15's

Trental 400 Tablet 15's belongs to a class of medicines called Hemorrheologic agents (affects blood viscosity), primarily used to treat pain in the legs due to insufficient blood flow (intermittent claudication). It also reduces cramping, numbness, or weakness in the legs on walking in such patients. Intermittent claudication is a peripheral vascular disease in which you have cramp-like pain in your legs when you walk and is caused by an insufficient blood supply in your legs.

Trental 400 Tablet 15's works by decreasing the viscosity (thickness) of blood, allowing it to pass more easily through the blood vessels, especially in the small blood vessels of the hands and feet. It can also increase the distance you can walk without pain since it improves your legs' blood circulation. It is recommended in patients whose pain has not improved even after lifestyle changes like quitting smoking and doing regular exercise.

Trental 400 Tablet 15's should be taken regularly in dose and duration as advised by the doctor. Your doctor will advise you on the exact dosage and how often you have to take Trental 400 Tablet 15's based on your medical condition. You may experience nausea, vomiting, diarrhoea, headache, lightheadedness, sleep problems, intrahepatic cholestasis (removal of bile from the liver is blocked), abdomen pain, constipation, and urine discolouration in some cases. Most of these side effects of Trental 400 Tablet 15's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Trental 400 Tablet 15's should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side effects. Inform your doctor before starting Trental 400 Tablet 15's if you have any kidney or liver disease or plan to become pregnant, or are breastfeeding. Also, lifestyle changes should be continued with Trental 400 Tablet 15's for best results. Do not take Trental 400 Tablet 15's if you ever had bleeding in your brain or the retina of your eyes, heart failure, chest pain, heart disease, and blood pressure.

Uses of Trental 400 Tablet 15's

Intermittent claudication

Medicinal Benefits

Trental 400 Tablet 15's contains 'Pentoxyfilline', which is a peripheral vasodilator that works by decreasing the viscosity (thickness) of blood, allowing it to pass more easily through the blood vessels, especially in the small blood vessels of the hands and feet. It can also increase the distance you can walk without pain since it improves your legs' blood circulation. It is recommended in patients whose pain has not improved even after lifestyle changes like quitting smoking and doing regular exercise.

Directions for Use

Swallow Trental 400 Tablet 15's as a whole with water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trental 400 Tablet 15's

  • Nausea
  • Vomiting
  • Diarrhoea
  • Headache
  • Lightheadedness
  • Sleep problems
  • Intrahepatic cholestasis (removal of bile from the liver is blocked)
  • Abdomen pain
  • Constipation
  • Urine discolouration

Drug Warnings

Do not take Trental 400 Tablet 15's if you are allergic to any of its components. Inform your doctor if you are pregnant or breastfeeding. Before taking Trental 400 Tablet 15's, please tell your doctor if you are using any blood thinners, as it can increase the risk of severe bleeding. Trental 400 Tablet 15's is not intended for prolonged use unless prescribed by a physician. Inform your doctor if have had any type of bleeding in your brain or the retina of your eyes, have low blood pressure (less than 90 mm of Hg), or have had a heart attack, kidney disease, or liver disease. Tell your doctor that you are using Trental 400 Tablet 15's before undergoing any dental or other surgery. Your doctor might stop this medicine before the surgery. Trental 400 Tablet 15's should not be stopped abruptly without consulting the doctor as it may lead to unpleasant side effects. Also, lifestyle changes should be continued with Trental 400 Tablet 15's for best results and a speedy recovery.

Drug Interactions

Drug-Drug Interaction: Trental 400 Tablet 15's may interact with blood thinners (warfarin, clopidogrel, aspirin), antibiotics (ciprofloxacin), pain relievers (ketorolac, diclofenac, indomethacin), antihypertensive (metoprolol, atenolol, propranolol, prazosin), antidiabetics (metformin, alogliptin, linagliptin, saxagliptin, sitagliptin, canagliflozin), a drug used to treat lung diseases (theophylline), diuretics (furosemide, chlorothiazide, indapamide, metolazone), 

Drug-Food Interaction: No interaction found/established.

Drug-Disease Interaction: Trental 400 Tablet 15's should be taken with caution in people who have bleeding problems, have had a heart attack, liver or kidney disease.

Drug-Drug Interactions Checker List

  • WARFARIN
  • CLOPIDOGREL
  • ASPIRIN
  • CIPROFLOXACIN
  • KETOROLAC
  • DICLOFENAC
  • INDOMETHACIN
  • METOPROLOL
  • ATENOLOL
  • PROPRANOLOL
  • PRAZOSIN
  • METFORMIN
  • LINAGLIPTIN
  • SAXAGLIPTIN
  • SITAGLIPTIN
  • CANAGLIFLOZIN
  • THEOPHYLLINE
  • FUROSEMIDE
  • CHLOROTHIAZIDE
  • INDAPAMIDE
  • METOLAZONE

Habit Forming

No

Diet & Lifestyle Advise

  • Opt for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.
  • Lsodium chloride (table salt) intake alt) in your daily diet.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress. Try to enjoy and spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Try to include heart-healthy omega-3 fatty acid-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Special Advise

Your doctor may advice you to get regular blood tests done to monitor liver function while taking Trental 400 Tablet 15's as it might cause liver injury.

Disease/Condition Glossary

Intermittent claudication: It is a peripheral vascular disease in which you have cramp-like pain in your legs when you walk and is caused by an insufficient blood supply in your legs.

Country of origin

INDIA

Manufacturer/Marketer address

Millennium City Information Technology Park, Tower-II, Plot No. 62, Block-DN, Sector V, 8th floor, Salt Lake, Kolkata: 700 091
Other Info - TRE0004

FAQs

No, you should not stop taking Trental 400 Tablet 15's even if you feel better as the pain might come back and become even worse.
No, it is a prescribed drug given by a physician to prevent specific medical conditions. Taking it on your own can cause unwanted side effects.
Trental 400 Tablet 15's is not a blood thinner. Trental 400 Tablet 15's contains 'Pentoxifylline' that belongs to a group of medicines called peripheral vasodilators, primarily used to treat pain in the legs due to insufficient blood flow (intermittent claudication).
If you forget to take Trental 400 Tablet 15's at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.
You are not recommended to take Trental 400 Tablet 15's with warfarin as co-administration of these two medicines may increase the risk of bleeding. However, if you experience severe bleeding, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted to use safely.

Disclaimer

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Alcohol

Caution

Avoid consumption of alcohol with Trental 400 Tablet 15's as it may increase adverse effects such as dizziness, fainting, light-headedness or headache.

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Pregnancy

Caution

Trental 400 Tablet 15's is a Category C pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Please consult a doctor if you are pregnant.

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Breast Feeding

Unsafe

Trental 400 Tablet 15's is not recommended for breastfeeding mothers as it may harm the baby.

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Driving

Caution

Drive with caution, Trental 400 Tablet 15's may cause blurry vision, and dizziness or weariness.

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Liver

Caution

Trental 400 Tablet 15's to be taken with caution, especially if you have a history of liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Trental 400 Tablet 15's to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Trental 400 Tablet 15's is not recommended for children. The safety and effectiveness of Trental 400 Tablet 15's have not been established in children.

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