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  3. Tresiba 100U/ml Penfil Injection 3 ml

Tresiba 100U/ml Penfil Injection 3 ml , Pack of 1 INJECTION
Tresiba 100U/ml Penfil Injection 3 ml , Pack of 1 INJECTION
Tresiba 100U/ml Penfil Injection 3 ml , Pack of 1 INJECTION
Tresiba 100U/ml Penfil Injection 3 ml , Pack of 1 INJECTION
Tresiba 100U/ml Penfil Injection 3 ml , Pack of 1 INJECTION
Tresiba 100U/ml Penfil Injection 3 ml , Pack of 1 INJECTION
Tresiba 100U/ml Penfil Injection 3 ml , Pack of 1 INJECTION
Tresiba 100U/ml Penfil Injection 3 ml , Pack of 1 INJECTION
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Reviewed By Sunny S , MBBS
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Composition :

INSULIN DEGLUDEC-100IU

Manufacturer/Marketer :

Novo Nordisk India Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Tresiba 100U/ml Penfil Injection 3 ml

Tresiba 100U/ml Penfil Injection 3 ml belongs to a group of medication called 'anti-diabetic' primarily used for the treatment of type 1 and type 2 diabetes mellitus in both children (above 1 year of age) and adults. Diabetes is a disease where your body does not produce enough insulin to control the level of your blood sugar. Treatment with Tresiba 100U/ml Penfil Injection 3 ml helps to prevent complications from your diabetes.

Tresiba 100U/ml Penfil Injection 3 ml contains insulin degludec which is a fast-acting insulin that works rapidly to normalize blood sugar levels by helping the sugar move from the blood into other tissues of the body. It typically begins working after 60 minutes and is a long-acting insulin preparation (lasts for more than 24 hours). It prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver.

In patients with type 1 diabetes, Tresiba 100U/ml Penfil Injection 3 ml must be used with another type of insulin (like with short-acting insulin). On the other hand, in patients with type 2 diabetes, Tresiba 100U/ml Penfil Injection 3 ml can be used with another type of insulin or with oral antidiabetic medicines. The common side effects of Tresiba 100U/ml Penfil Injection 3 ml are hypokalaemia (low potassium), hypoglycemia (low blood sugar level), local injection site reactions, lipodystrophy (fat deposition under the skin), rash, and pruritus (itch skin) which may occur at the injection site. Most of these side effects of Tresiba 100U/ml Penfil Injection 3 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking Tresiba 100U/ml Penfil Injection 3 ml of your own. Let your doctor know about this, as it may cause withdrawal symptoms. Do not take Tresiba 100U/ml Penfil Injection 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs. Along with Tresiba 100U/ml Penfil Injection 3 ml , you should take a healthy diet, do regular exercise, and maintain weight as advised by your doctor. Tresiba 100U/ml Penfil Injection 3 ml is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might get lost. Do not store in the freezer of the fridge.
 

Uses of Tresiba 100U/ml Penfil Injection 3 ml

Type 1 diabetes mellitus, Type 2 diabetes mellitus

Directions for Use

Tresiba 100U/ml Penfil Injection 3 ml is for subcutaneous (under the skin) use only. However, in rare cases, it can be given via infusion intravenously under medical supervision. Wash your hands properly and adjust the dose as advised by the doctor. Clean the injection site and inject the dose subcutaneously into the abdomen area. Safely discard the needle. Your doctor will advise for how long you need to take Tresiba 100U/ml Penfil Injection 3 ml based on your medical condition.

Medicinal Benefits

Tresiba 100U/ml Penfil Injection 3 ml works by ensuring rapid and consistent sugar control. Tresiba 100U/ml Penfil Injection 3 ml is a long-acting synthetic form of insulin that helps lower blood sugar levels by replacing the insulin that is produced by the body naturally. This drug also helps in moving sugar from the blood into different parts of the body so that body can effectively use the sugar in producing energy. Prevents the risk of having severe complications of diabetes. It stimulates the recovery of sugar in muscle and fat cells and thus suppresses the production of sugar in the liver. Tresiba 100U/ml Penfil Injection 3 ml helps in improving the glycaemic control which in turn decreases the risk of progression of complications of diabetes like damage of retina (retinopathy), damage of kidney (nephropathy), damage of nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer, and others. Besides this, Tresiba 100U/ml Penfil Injection 3 ml can be safely prescribed to the diabetic mother in the pregnancy as well as lactation stage.

Storage

Store in a cool and dry place away from sunlight
Side effects of Tresiba 100U/ml Penfil Injection 3 ml
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to manage the medication-triggered Sinusitis (Sinus infection or Inflammation Of Sinuses):
  • Consult your doctor if you experience symptoms of sinusitis, such as nasal congestion, facial pain, or headaches, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your sinusitis symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • If your doctor advises, you can use nasal decongestants or saline nasal sprays to help relieve nasal congestion and sinus pressure.
  • To help your body recover, get plenty of rest, stay hydrated, and engage in stress-reducing activities. If your symptoms persist or worsen, consult your doctor for further guidance.
  • Get ample rest; this helps your stomach to settle.
  • Eat soft and easy-to-digest foods like white rice, bananas, crackers and apple sauce.
  • Include probiotics-rich food like yoghurt, kefir, or miso, as they help maintain gut functioning.
  • Wash your hands properly before preparing/eating food and after using the toilet.
  • Drink water, broth or diluted fruit juice to replace electrolytes and lost fluids.
  • Avoid caffeine, alcohol, high-fat, fried and fast foods, as well as sweetened beverages.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
Here are the steps to manage the medication-triggered Common Cold:
  • Inform your doctor about the common cold symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Drink plenty of fluids, such as warm water or soup, to help thin out mucus.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.

Drug Warnings

Tresiba 100U/ml Penfil Injection 3 ml is for subcutaneous (under the skin) use only. However, in rare cases, it can be given via infusion intravenously under medical supervision. If you are changing the insulin brand or if you need to inject your insulin by another method, it should be done under strict medical supervision. Cases of heart failure have been reported when pioglitazone was used with insulin, especially in patients at high risk of cardiac heart failure. The first hyperglycemia symptoms (high blood sugar level) may include excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite, and acetone odour of the breath. You should closely monitor these symptoms. Symptoms like heart failure, weight gain, and oedema (fluid deposition in tissue) should not be overruled. It is advisable not to consume alcohol as it may either increase or decrease your blood glucose level. Care should be taken while travelling across more than two time zones. Your doctor may adjust your insulin schedule. Tresiba 100U/ml Penfil Injection 3 ml may decrease the level of potassium, leading to a state of hypokalaemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma, and even death. Do not take Tresiba 100U/ml Penfil Injection 3 ml if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.

Drug-Drug Interactions

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Insulin degludecCinoxacin
Severe
Insulin degludecOfloxacin
Severe

Drug-Drug Interactions

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Insulin degludecCinoxacin
Severe
How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with cinoxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and Cinoxacin, it can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin degludecOfloxacin
Severe
How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with ofloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and ofloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin degludecCiprofloxacin
Severe
How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with ciprofloxacin can effect blood sugar levels, both hyperglycemia (high blood sugar) and, less frequently, hypoglycemia (low blood sugar).

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and Ciprofloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, excessive sweating, and rapid heartbeat, increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin degludecLevofloxacin
Severe
How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Coadministration of levofloxacin and Tresiba 100U/ml Penfil Injection 3 ml can sometimes affect blood glucose levels - Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose).

How to manage the interaction:
Although using levofloxacin and Tresiba 100U/ml Penfil Injection 3 ml at the same time may cause an interaction, they can be taken together if a doctor has prescribed it. Inform doctor if you develop hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose), or if you have trouble controlling your blood glucose. Hypoglycemia symptoms include headache, dizziness, tiredness, anxiety, disorientation, a shaking sensation, nausea, hunger, weakness, sweating, palpitation, and a rapid pulse. Hyperglycemia symptoms include Increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin degludecMoxifloxacin
Severe
How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with Moxifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and Moxifloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience headache, dizziness, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin degludecNorfloxacin
Severe
How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with norfloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and norfloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin degludecTrovafloxacin
Severe
How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with trovafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and trovafloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.
Insulin degludecEnoxacin
Severe
How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with Enoxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia(low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and cinoxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin degludecGrepafloxacin
Severe
How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with grepafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and grepafloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.
Insulin degludecNalidixic acid
Severe
How does the drug interact with Tresiba 100U/ml Penfil Injection 3 ml :
Taking Tresiba 100U/ml Penfil Injection 3 ml with nalidixic acid affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Tresiba 100U/ml Penfil Injection 3 ml and nalidixic but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercise may lower your body’s need for insulin during and for some time after the physical activity.
  • Exercise may also speed up the effect of an insulin dose, especially if the exercise involves the area of the injection site (for example, the leg should not be used for injection just prior to running). 
  • Discuss with your doctor how you should adjust your insulin regimen to accommodate exercise. 
  • Avoid eating sugar food and prefer food cooked food low in calories.
  • When traveling across more than 2 time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Tresiba 100U/ml Penfil Injection 3 ml is only a part of a complete diabetes control program that includes regular blood sugar testing, diet, exercise, weight control, and special medical care. So follow all the instructions given by the doctor.

It is advised to tell all the medicines that you are using like pioglitazone or rosiglitazone as taking other diabetes medicines may increase the risk of serious heart problems.

Tresiba 100U/ml Penfil Injection 3 ml typically begins working after 60 minutes and will last for more than 24 hours.

Tresiba 100U/ml Penfil Injection 3 ml can be given to treat both the condition of type 1 and type 2 diabetes mellitus. However, your doctor will decide whether Tresiba 100U/ml Penfil Injection 3 ml can be given to you or not depending on your present condition. Tresiba 100U/ml Penfil Injection 3 ml should be avoided in patients who are allergic to Tresiba 100U/ml Penfil Injection 3 ml or other forms of insulin, patients with kidney disease, liver disease, low blood sugar/glucose level (hypoglycemia), and low potassium level (hypokalaemia).

Try to avoid intake of alcoholic beverages with Tresiba 100U/ml Penfil Injection 3 ml as it may increase or decrease your blood sugar level.

Cold sweat; cool pale skin; headache; rapid heartbeat; feeling sick; feeling very hungry; temporary vision changes; drowsiness; unusual tiredness and weakness; nervousness or tremor; feeling anxious; feeling confused; difficulty in concentrating are some of the common signs of the low blood sugar level in an individual.

If you experience low blood sugar, eat glucose tablets, or another high sugar snack (e.g. sweets, biscuits, fruit juice). Measure your blood sugar if possible and rest. Always carry glucose tablets or high sugar snacks with you. You should give a call to any of your family members if you are feeling dizziness or drowsiness.

Local allergic reactions (pain, redness, hives, inflammation, bruising, swelling, and itching) at the injection site may occur. These usually disappear after a few weeks of taking your insulin. If they do not disappear, or if they spread throughout your body, talk to your doctor immediately.

You can inject Tresiba 100U/ml Penfil Injection 3 ml in your upper arm, thigh, or stomach area. Do not inject Tresiba 100U/ml Penfil Injection 3 ml into your vein or muscle. Try to change (rotate) the injection site with each dose to avoid skin irritation in the same injection site.

If you have opened the insulin pen once, it must be stored at room temperature (25-degree Celsius) and may be used for up to 56 days after its first use.

Drug-Drug Interactions Checker List

  • LEVOTHYROXINE SODIUM
  • METOPROLOL
  • FUROSEMIDE
  • ASPIRIN

Special Advise

  • Your doctor may tell you to have a regular potassium level as prolonged administration causes a life-threatening condition of hypokalemia (low potassium). 
  • Do not mix Tresiba 100U/ml Penfil Injection 3 ml with other insulin form or dilute it.
  • Store Tresiba 100U/ml Penfil Injection 3 ml between 2-8 degree celsius temperature only. 

Disease/Condition Glossary

Type 1 diabetes mellitus: In type 1 diabetes mellitus, our body does not make insulin (the hormone which helps to decrease sugar levels in the blood) to control blood sugar levels.

Type 2 diabetes mellitus: In type 2 diabetes mellitus, either the body stops producing enough insulin, or there is resistance to the action of insulin. As a result, insulin is produced in sufficient amounts but is unable to act on the tissues of the organs.

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