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Consume Type

ORAL

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Not Returnable

Expires on or after

Apr-24

for this medicine

About Trilopace Tablet 10's

Trilopace Tablet 10's is an 'anti-hypertensive' medication primarily used in the treatment of high blood pressure (hypertension). High blood pressure or hypertension is a chronic condition in which the blood's force against the walls of blood vessels, is consistently too high. As a result, this can ultimately lead to heart-related conditions like heart failure, stroke, and irregular heartbeat.

Trilopace Tablet 10's is a combination of three medicines namely: Amlodipine, Hydrochlorothiazide, and Losartan. Amlodipine belongs to class medicines known as calcium channel blocker that dilates (widens) blood vessels and increases blood flow. It helps to lower blood pressure, reduce chest pain (angina), and other complications caused by coronary artery disease. Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolytes overload from the body. Losartan belongs to class medicines known as angiotensin receptor blocker (ARB) that works by blocking the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. Thus, all together Trilopace Tablet 10's helps in controlling high blood pressure.

You may experience nausea, altered taste, diarrhea, stomach upset, dizziness, flushing (sense of warmth in the face, ears, neck, and trunk), headache, numbness (lost, reduced, or altered sensation) of extremity in some cases. Most of these side effects of Trilopace Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless the doctor has told you. If you notice unexplained muscle pain, dark color urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Try not to stop taking this medicine on your own. Let your doctor know about this, as stopping abruptly may provoke rapid upswings in blood pressure. Inform your doctor before starting this medication course if you are suffering from kidney, liver, or heart disease. Pregnant and breastfeeding women should not take Trilopace Tablet 10's without proper consultation or inputs from their OB/GYN.

Uses of Trilopace Tablet 10's

Hypertension (high blood pressure)

Directions for Use

Swallow Trilopace Tablet 10's as a whole with water. Do not chew, crush, or break it.

Medicinal Benefits

Trilopace Tablet 10's is a combination of three medicines, namely: Amlodipine, Hydrochlorothiazide, and Losartan. Amlodipine belongs to class medicines known as calcium channel blockers. Amlodipine is known to work by inhibiting the entry of calcium ions across cardiac (heart) and smooth muscle causing relaxation and dilation (widening) of these muscles. Amlodipine does not change serum calcium concentrations. Hydrochlorothiazide is a diuretic or water pill. Hydrochlorothiazide works by inhibiting the sodium chloride transport in the distal convoluted tubule (a portion of the kidney nephron). Along with accompanying fluid, more sodium is then excreted in the kidney. This increases the flow of urine and reduces the amount of water in the body, thereby helps in lowering blood pressure. Losartan is an angiotensin receptor blocker (ARB) that works by blocking the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. This allows the blood to flow more smoothly in the blood vessels, and the heart can pump more efficiently. Thus, all together Trilopace Tablet 10's helps in controlling high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trilopace Tablet 10's

  • Nausea
  • Altered taste
  • Stomach upset
  • Dizziness
  • Decreased blood pressure
  • Diarrhoea
  • Headache

Drug Warnings

Do not use Trilopace Tablet 10's if you are pregnant, planning for pregnancy, or if you are unable to urinate (anuria). Trilopace Tablet 10's may pass into breast milk, so before starting Trilopace Tablet 10's, either you need to stop nursing, or you should not take Trilopace Tablet 10's while breastfeeding. Please inform your doctor/surgeon before surgery that you are on Trilopace Tablet 10's as it needs to be stopped because it might lower the blood pressure further if taken along with certain anesthesia medication. Avoid intake of potassium salt or its substitute while using Trilopace Tablet 10's to avoid any electrolytes imbalance. Trilopace Tablet 10's should be used with extreme caution in patients with liver, kidney, cardiovascular diseases and diabetic patients. Use only if the potential benefit justifies the potential risk. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Drug-Drug Interactions

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HydrochlorothiazideCisapride
Critical
HydrochlorothiazideDofetilide
Critical

Drug-Drug Interactions

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HydrochlorothiazideCisapride
Critical
How does the drug interact with Trilopace Tablet:
Taking Cisapride and Trilopace Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Trilopace Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Trilopace Tablet:
Taking Dofetilide and Trilopace Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Trilopace Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
AmlodipineDantrolene
Critical
How does the drug interact with Trilopace Tablet:
Using Trilopace Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Trilopace Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
HydrochlorothiazideDolasetron
Severe
How does the drug interact with Trilopace Tablet:
Co-administration of Dolasetron and Trilopace Tablet can affect the rhythm of your heart which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dolasetron and Trilopace Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision, nausea, and seizures, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazidePimozide
Severe
How does the drug interact with Trilopace Tablet:
The combined use of Pimozide and Trilopace Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Pimozide and Trilopace Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDronedarone
Severe
How does the drug interact with Trilopace Tablet:
Co-administration of Dronedarone and Trilopace Tablet can increase the risk of severe irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dronedarone and Trilopace Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideLithium
Severe
How does the drug interact with Trilopace Tablet:
Coadministration of Lithium and Trilopace Tablet can increase the effects of lithium.

How to manage the interaction:
Taking Lithium and Trilopace Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideTizanidine
Severe
How does the drug interact with Trilopace Tablet:
The combined use of Tizanidine and Trilopace Tablet can have additive effects in lowering your blood pressure.

How to manage the interaction:
Taking Tizanidine and Trilopace Tablet together can possibly result in an interaction, but they can be taken if advised by your doctor. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideAmiodarone
Severe
How does the drug interact with Trilopace Tablet:
Coadministration of Amiodarone together with Trilopace Tablet may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Trilopace Tablet interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideZiprasidone
Severe
How does the drug interact with Trilopace Tablet:
Taking Ziprasidone and Trilopace Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Ziprasidone and Trilopace Tablet together is avoided as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Keep your weight under control with BMI of 19.5-24.9.
  • Limit intake of sodium chloride (table salt) in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega 3 fatty acids-containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.
  • Option for a diet rich in whole grains, fruits, veggies, and low-fat dairy products.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Trilopace Tablet 10's Substitute

Substitutes safety advice
  • Amlozaar-H Tablet 15's

    by Others

    15.36per tablet
  • Amlozaar H Tablet 10's

    by Others

    21.06per tablet
  • Resitan AMH Tablet 10's

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    13.14per tablet
  • Nusar-AMH Tablet 10's

    by Others

    9.54per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • LITHIUM
  • DULOXETINE
  • ALPRAZOLAM
  • METFORMIN
  • METOPROLOL
  • ASPIRIN
  • IBUPROFEN

Special Advise

Keep a check on your daily blood pressure, and if you notice any fluctuations, please consult a doctor. A low salt/sodium diet and regular exercise are recommended along with Trilopace Tablet 10's for effective results.

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is consistently measures >130 mmHg systolic and >80 mmHg diastolic. Hypertension can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. Diastolic pressure is when the heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

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