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  3. TRILOSACAR TABLET

TRILOSACAR TABLET, Pack of 10 TABLETS
Written By ,
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

AMLODIPINE-5MG + CHLORTHALIDONE-12.5MG + LOSARTAN-50MG

Manufacturer/Marketer :

Zydus Cadila

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About TRILOSACAR TABLET

TRILOSACAR TABLET belongs to a group of medicines known as anti-hypertensives, primarily used to treat high blood pressure, heart failure, and oedema (a buildup of fluid in the body). Hypertension or high blood pressure is a lifelong or chronic condition in which the force exerted by the blood against the blood vessel (arteries wall) increases. The higher this blood pressure, the harder the heart has to pump. Oedema may occur in high blood pressure where fluids of the body get trapped in the tissues of the hands, arms, feet, ankles and legs, leading to swelling.

TRILOSACAR TABLET contains Chlorothiazide, Losartan and Amlodipine. Chlorothiazide is a diuretic that works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats Edema (swelling) associated with heart, liver, kidney or lung disease. Amlodipine is a calcium channel blocker, and Losartan is an angiotensin receptor antagonist. Both work by relaxing and widening the blood vessels. This, in turn, reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. So, it helps to lower high blood pressure, reducing the chances of heart attack or stroke.

Take TRILOSACAR TABLET as prescribed by your doctor. Depending on your medical conditions, you are advised to take TRILOSACAR TABLET for as long as your doctor has prescribed it for you. You may experience glucose intolerance (low or high level of glucose), ankle swelling, sleepiness, headache (sense of heat in the face, ears, neck, and trunk), flushing, tiredness, nausea, decreased potassium level in the blood, Increased blood uric acid and altered blood lipid level. Most of these side effects of TRILOSACAR TABLET do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Try not to stop taking this medicine of your own. Tell your doctor about this, as it may cause a rise in blood pressure and increase the risk of heart complications like stroke and heart disease. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes. Taking TRILOSACAR TABLET during pregnancy may cause side effects like jaundice (yellowing of the skin or eyes), unexplained bleeding, low blood sugar or an electrolyte imbalance in the newborn baby. Do not use the TRILOSACAR TABLET if you cannot urinate, have low blood pressure (hypotension), and have a cardiogenic shock (sudden stopping blood flow to the heart). Reducing the amount of table salt (sodium chloride) in your food often relieves the body's swelling.

Uses of TRILOSACAR TABLET

Hypertension (high blood pressure), Oedema (swelling due to fluid retention)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

TRILOSACAR TABLET is a combination drug used to treat hypertension. When you take TRILOSACAR TABLET, your body's blood vessels will be relaxed, and it will help lower the raised blood pressure. It also widens the blood vessels (lining of arteries wall) and improves blood flow. It helps in losing out excess fluids from the body by increasing the production of urine. This reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Thus, it helps to lower high blood pressure, reducing the chances of heart attack or stroke. TRILOSACAR TABLET also helps decrease fluid buildup, which reduces inflammation or swelling. In addition, this relieves Oedema and enables you to carry out your daily activities more efficiently.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

TRILOSACAR TABLET should not be given to the people allergic to TRILOSACAR TABLET, have low blood pressure (less than 90 mm of Hg), have had a heart attack, kidney disease, liver disease, gout (high uric acid), high cholesterol (hyperlipidemia), pregnant women or planning to get pregnant and breastfeeding women. Besides this, it is contraindicated in people with cardiogenic shock (sudden stopping of blood flow to the heart) and aortic stenosis (heart valve problem). TRILOSACAR TABLET can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take TRILOSACAR TABLET and breastfeeding. Tell your doctor if you are on low sodium (table salt) diet. Cases of electrolyte imbalance have been observed (like low levels of sodium, potassium, or magnesium in your blood). So your doctor might advise monitoring blood pressure, kidney function tests and electrolytes.

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
chlorthalidoneCisapride
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Trilosacar Tablet:
Using Trilosacar Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Trilosacar Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
chlorthalidoneCisapride
Critical
How does the drug interact with Trilosacar Tablet:
Co-administration of Trilosacar Tablet and cisapride may increase the risk or severity of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Trilosacar Tablet with Cisapride is not recommended, please consult your doctor before taking it. Do not discontinue the medication without consulting a doctor.
AmlodipineCarbamazepine
Severe
How does the drug interact with Trilosacar Tablet:
Coadministration of Trilosacar Tablet and carbamazepine together may significantly reduce Trilosacar Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Trilosacar Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineSimvastatin
Severe
How does the drug interact with Trilosacar Tablet:
Taking simvastatin with Trilosacar Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Trilosacar Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
AmlodipineRifampicin
Severe
How does the drug interact with Trilosacar Tablet:
Coadministration of Trilosacar Tablet and rifampicin together may lower Trilosacar Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Trilosacar Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineDolasetron
Severe
How does the drug interact with Trilosacar Tablet:
Using dolasetron together with Trilosacar Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
There may be a possibility of interaction between Trilosacar Tablet and Dolasetron, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like feeling dizzy, lightheaded, or your heart beating irregularly, it's important to call a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineSirolimus
Severe
How does the drug interact with Trilosacar Tablet:
Co-administration of Trilosacar Tablet can make Sirolimus may increase the risk of angioedema (a condition associated with swelling of the face, eyes, lips, tongue, throat, and occasionally also the hands and feet).

How to manage the interaction:
There may be a possibility of interaction between Trilosacar Tablet and Sirolimus, but it can be taken if prescribed by a doctor. However, consult the doctor if you notice any swelling of the face, eyes, lips, tongue, throat, hands and feet or have trouble breathing or swallowing. Do not stop using any medications without a doctor's advice.
AmlodipineIdelalisib
Severe
How does the drug interact with Trilosacar Tablet:
Coadministration of Trilosacar Tablet and Idelalisib may raise Trilosacar Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Trilosacar Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipinePhenytoin
Severe
How does the drug interact with Trilosacar Tablet:
Using Trilosacar Tablet and phenytoin together may drastically lower Trilosacar Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Trilosacar Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineFosphenytoin
Severe
How does the drug interact with Trilosacar Tablet:
When Trilosacar Tablet is taken with Fosphenytoin, it may decrease the blood levels of Trilosacar Tablet, which may make Trilosacar Tablet less effective.

How to manage the interaction:
Although taking Trilosacar Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.
  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.
  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.
  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.
  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.
  • Avoid the consumption of too much salt or salty food.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Regular physical activity or exercise like walking improves your blood flow.
  • When possible, elevate your legs or the swollen area on a chair or pillows.
  • Avoid standing or sitting for extended periods of time.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

TRILOSACAR TABLET Substitute

Substitutes safety advice

Product Substitutes

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

TRILOSACAR TABLET contains Chlorothiazide, Losartan and Amlodipine. Chlorothiazide works by increasing the amount of urine passed out from the kidneys. It effectively reduces excess fluid levels in the body and treats Oedema (swelling) associated with heart, liver, kidney or lung disease. Amlodipine and Losartan work by relaxing and widening the blood vessels. This, in turn, reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body.

Also known as 'dropsy' or 'hydropsy,' it is a condition of fluid retention in the body characterized by swelling of the body's tissue, including ankles, feet and legs. It is usually caused by standing or sitting in the same position for too long, eating too much salty food and being overweight. Edema mainly affects the lymphatic system (including the circulatory and immune systems) and organs like the tonsils, spleen and thymus, maintaining fluid balance and fights infections. If it does not subside, please consult your doctor immediately.

TRILOSACAR TABLET can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.

It's unlikely that TRILOSACAR TABLET affects fertility in men or women. However, some water pills like hydrochlorothiazide may lead to erectile dysfunction. There's not enough evidence to say for certain. For the best advice, consult your doctor.

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend discontinuing it.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • RAMIPRIL
  • HYDROCHLOROTHIAZIDE
  • ATORVASTATIN
  • SILDENAFIL
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • CYCLOSPORINE
  • IBUPROFEN
  • ASPIRIN
  • RIFAMPICIN
  • ZIPRASIDONE
  • LITHIUM

Disease/Condition Glossary

Hypertension: The blood exerts increased pressure on the walls of blood vessels leading to hypertension. High blood pressure is expressed as systolic/diastolic pressure. Systolic pressure is the pressure in the arteries when the heart beats or pumps out blood. Diastolic pressure is the pressure in the arteries between the heartbeats. Blood pressure is measured in millimetres of mercury (mmHg) by a blood pressure monitor called a sphygmomanometer. Some of the symptoms are headache, dizziness, nosebleeds, altered vision, chest pain, weakness, and shortness of breath. However, most of the time, the signs and symptoms of hypertension are none.

Oedema: Oedema, also known as fluid overload, occurs due to fluid build-up in spaces between the cells. Oedema can result from a variety of factors. Some oedema reasons are caused by your lifestyle, while an underlying medical problem causes others. Shortness of breath, chest pain (angina), abnormal heart rhythms (arrhythmia), and swelling in hands or abdominal areas are the symptoms of oedema.

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