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Reviewed By Sureshvarma D , MPharma
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Manufacturer/Marketer

Lupin Ltd

Consume Type

INHALATION

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Trimium Transhaler

Trimium Transhaler belongs to the class 'respiratory stimulants', which are primarily used to treat asthma symptoms and chronic obstructive pulmonary diseases (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Trimium Transhaler is a combination of three drugs: Tiotropium (anti-cholinergic), Formoterol (LABA - long-acting beta-agonists or bronchodilator), and ciclesonide (corticosteroid). Tiotropium is an anti-cholinergic, and formoterol is a bronchodilator. Both medicines work by relaxing the airway muscles and widen the airways. These medicines together making it easier for asthma and COPD patients to breathe. Whereas ciclesonide is a corticosteroid, it acts by stopping the release of certain natural substances in the body that are responsible for inflammation of the airways.

Your doctor will recommend how often you take Trimium Transhaler based on your medical condition. Some people may experience side effects like a fungal infection in the mouth, vomiting, nausea, headache, sore throat, hoarse voice, upper respiratory tract infection, flu, cough, Musculoskeletal (bone, muscle, or joint) pain, increased heart rate, and trembling. Most of these side effects of Trimium Transhaler do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, stop the medicine and consult your doctor.

If you are allergic to lactose (a form of sugar) or have lactose intolerance, Trimium Transhaler, or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Trimium Transhaler. Trimium Transhaler is not recommended for children below 6 years of age. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, or last longer than usual, please consult a doctor immediately. These might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Trimium Transhaler as it may cause low potassium levels in the blood. If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), fits, immune system problems, chickenpox, measles, thyroid, lung, heart, liver, or adrenal gland problems, tuberculosis inform your doctor before taking Trimium Transhaler. Trimium Transhaler should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia, or bladder neck obstruction.

Uses of Trimium Transhaler

Asthma and Chronic obstructive pulmonary disease (COPD).

Directions for Use

Inhaler/Transhaler: Shake the inhaler well and check the label for directions before using. While you breathe the medication from the mouth, press down the inhaler once to release the medicine and hold your breath for 10 seconds. Repeat until you have inhaled the number of puffs as advised by your doctor. Rinse your mouth with water and spit it out after using.Rotacaps/Transcaps: It is a capsule with powdered medication which is placed in rotahaler/transhaler, a plastic inhalation device that releases the medication when you breathe. It is for inhalation only. Do not swallow the capsule. The capsule should be placed at the base of the rotahaler/transhaler, and completely twist the mouthpiece until you hear a click sound. Then, breathe in through the mouthpiece deeply and hold your breath for 10 seconds. Remove the device and breathe out normally.Respules/Transpules: Respule/Transpule is a small plastic container that contains a solution. Twist off the top of the respule/transpule and squeeze the solution into the nebuliser. This solution is made into a fine mist to breathe in. Inhale the medicine through the nebuliser's mouthpiece.

Medicinal Benefits

Trimium Transhaler is a combination of three drugs: Tiotropium (anti-cholinergic), Formoterol (LABA - long-acting beta-agonists or bronchodilator), and ciclesonide (corticosteroid). Tiotropium is an anti-cholinergic, and formoterol is a bronchodilator. Both medicines work by relaxing the airway muscles and widen the airways. These medicines together making it easier for asthma and COPD patients to breathe. Whereas ciclesonide is a corticosteroid, it acts by stopping the release of certain natural substances in the body that are responsible for inflammation of the airways.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Trimium Transhaler

  • Fungal infection in the mouth
  • Vomiting
  • Nausea
  • Headache
  • Sore throat, hoarse voice
  • Upper respiratory tract infection
  • Flu, cough
  • Musculoskeletal pain (bone, muscle or joint)
  • Increased heart rate
  • Increased intraocular pressure (pressure inside the eye is higher than normal)
  • Shaking or trembling

Drug Warnings

If you are allergic to lactose (a form of sugar) or have lactose intolerance, Trimium Transhaler, or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Trimium Transhaler. Trimium Transhaler is not recommended for children below 6 years of age. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, or last longer than usual, please consult a doctor immediately. These might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Trimium Transhaler as it may cause low potassium levels in the blood. If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), epilepsy, immune system problems, chickenpox, measles, thyroid, lung, heart, liver, or adrenal gland problems, tuberculosis inform your doctor before taking Trimium Transhaler. Trimium Transhaler should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia, or bladder neck obstruction.

Drug-Drug Interactions

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CiclesonideDesmopressin
Critical
FormoterolPropranolol
Severe

Drug-Drug Interactions

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CiclesonideDesmopressin
Critical
How does the drug interact with Trimium Transhaler:
Co-administration of Bumetanide and Desmopressin may increase the risk of hyponatremia (low levels of salt in the blood).

How to manage the interaction:
If you have to use Desmopressin and Trimium Transhaler together, a doctor may adjust the dose or monitor you more frequently to safely use both medications. However, if you experience loss of appetite, headache, nausea, vomiting, lethargy (very tired), irritability, difficulty concentrating, weakness, unsteadiness, memory impairment, confusion, muscle spasm, decreased urination, and/or sudden weight gain, contact your doctor immediately as these may be symptoms of water intoxication (water poisoning) and hyponatremia (low levels of salt in the blood). Do not discontinue the medication without consulting a doctor.
FormoterolPropranolol
Severe
How does the drug interact with Trimium Transhaler:
Coadministration of propranolol with Trimium Transhaler can reduce the effects of both medications.

How to manage the interaction:
Although taking propranolol and Trimium Transhaler together can result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolPenbutolol
Severe
How does the drug interact with Trimium Transhaler:
Using Trimium Transhaler together with penbutolol can reduce the effect of both medications.

How to manage the interaction:
There may be a possibility of interaction between Penbutolol and Trimium Transhaler, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolLabetalol
Severe
How does the drug interact with Trimium Transhaler:
Co-administration of labetalol and Trimium Transhaler together could decrease the effects of both medications.

How to manage the interaction:
Although taking Labetalol and Trimium Transhaler together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FormoterolNadolol
Severe
How does the drug interact with Trimium Transhaler:
Taking nadolol with Trimium Transhaler together could decrease the effects of both medications.

How to manage the interaction:
There may be a possibility of interaction between Trimium Transhaler and Nadolol, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolCarteolol
Severe
How does the drug interact with Trimium Transhaler:
Taking carteolol with Trimium Transhaler can reduce the effects of both drugs.

How to manage the interaction:
Although there is an interaction between Carteolol and Trimium Transhaler, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FormoterolCarvedilol
Severe
How does the drug interact with Trimium Transhaler:
Using Trimium Transhaler and Carvedilol together may reduce the effects of both medications.

How to manage the interaction:
Although there is an interaction between Trimium Transhaler and Carvedilol, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
FormoterolSotalol
Severe
How does the drug interact with Trimium Transhaler:
Taking sotalol with Trimium Transhaler could reduce the benefits of both medications because they have opposite effects on the body.

How to manage the interaction:
Although there is an interaction between Sotalol and Trimium Transhaler, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
FormoterolRibociclib
Severe
How does the drug interact with Trimium Transhaler:
Taking ribociclib together with Trimium Transhaler can increase the risk of an irregular heart rhythm

How to manage the interaction:
Co-administration of Trimium Transhaler with Ribociclib can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, or shortness of breath, contact your doctor right away. Do not stop using any medications without first talking to your doctor.
FormoterolTimolol
Severe
How does the drug interact with Trimium Transhaler:
Taking timolol with Trimium Transhaler could reduce the benefits of both medications because they have opposite effects on the body.

How to manage the interaction:
Although taking Trimium Transhaler and timolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms, contact your doctor immediately. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
  • Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon, and lime juice as it may worsen asthma symptoms.
  • Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
  • Quit smoking as it may reduce the effectiveness of the Trimium Transhaler and irritate the lungs worsening breathing problems.
  • Learning breathing exercises will help you move more air in and out of your lungs.
  • Limit alcohol intake.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS

Trimium Transhaler Substitute

Substitutes safety advice
  • Triohale Inhaler

    by Others

    5.60per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ALBUTEROL
  • PREDNISONE
  • FUROSEMIDE
  • AMILORIDE
  • ASPIRIN
  • AZITHROMYCIN
  • DULOXETINE
  • METOPROLOL
  • KETOCONAZOLE
  • RITONAVIR
  • PHENELZINE
  • POSACONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE

Special Advise

  • You are advised to rinse your mouth with water after each dose of Trimium Transhaler because it not only removes the taste of medicine inhaled but also helps to avoid fungal infections (oral thrush) in the mouth and throat. After rinsing your mouth thoroughly, you may drink water, milk, or any liquids.
  • Your doctor may advise regular monitoring of potassium, as the use of Trimium Transhaler may affect the body's potassium levels.

Disease/Condition Glossary

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises, and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath, or wheezing (whistle sound while breathing).

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