Trimium Transhaler belongs to the class 'respiratory stimulants', which are primarily used to treat asthma symptoms and chronic obstructive pulmonary diseases (COPD). Asthma is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus, leading to difficulty breathing. COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Trimium Transhaler is a combination of three drugs: Tiotropium (anti-cholinergic), Formoterol (LABA - long-acting beta-agonists or bronchodilator), and ciclesonide (corticosteroid). Tiotropium is an anti-cholinergic, and formoterol is a bronchodilator. Both medicines work by relaxing the airway muscles and widen the airways. These medicines together making it easier for asthma and COPD patients to breathe. Whereas ciclesonide is a corticosteroid, it acts by stopping the release of certain natural substances in the body that are responsible for inflammation of the airways.

Your doctor will recommend how often you take Trimium Transhaler based on your medical condition. Some people may experience side effects like a fungal infection in the mouth, vomiting, nausea, headache, sore throat, hoarse voice, upper respiratory tract infection, flu, cough, Musculoskeletal (bone, muscle, or joint) pain, increased heart rate, and trembling. Most of these side effects of Trimium Transhaler do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, stop the medicine and consult your doctor.

If you are allergic to lactose (a form of sugar) or have lactose intolerance, Trimium Transhaler, or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Trimium Transhaler. Trimium Transhaler is not recommended for children below 6 years of age. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, or last longer than usual, please consult a doctor immediately. These might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Trimium Transhaler as it may cause low potassium levels in the blood. If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), fits, immune system problems, chickenpox, measles, thyroid, lung, heart, liver, or adrenal gland problems, tuberculosis inform your doctor before taking Trimium Transhaler. Trimium Transhaler should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia, or bladder neck obstruction.

Trimium Transhaler is a combination of three drugs: Tiotropium (anti-cholinergic), Formoterol (LABA - long-acting beta-agonists or bronchodilator), and ciclesonide (corticosteroid). Tiotropium is an anti-cholinergic, and formoterol is a bronchodilator. Both medicines work by relaxing the airway muscles and widen the airways. These medicines together making it easier for asthma and COPD patients to breathe. Whereas ciclesonide is a corticosteroid, it acts by stopping the release of certain natural substances in the body that are responsible for inflammation of the airways.

• Fungal infection in the mouth
• Vomiting
• Nausea
• Headache
• Sore throat, hoarse voice
• Upper respiratory tract infection
• Flu, cough
• Musculoskeletal pain (bone, muscle or joint)
• Increased heart rate
• Increased intraocular pressure (pressure inside the eye is higher than normal)
• Shaking or trembling

If you are allergic to lactose (a form of sugar) or have lactose intolerance, Trimium Transhaler, or any other ingredients, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Trimium Transhaler. Trimium Transhaler is not recommended for children below 6 years of age. If your breathing worsens or you often wake up at night with asthma, experience chest tightness in the morning, or last longer than usual, please consult a doctor immediately. These might be signs indicating that your asthma is not controlled properly and requires an alternate or additional treatment. Regular monitoring of potassium levels is recommended while taking Trimium Transhaler as it may cause low potassium levels in the blood. If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), epilepsy, immune system problems, chickenpox, measles, thyroid, lung, heart, liver, or adrenal gland problems, tuberculosis inform your doctor before taking Trimium Transhaler. Trimium Transhaler should be used with caution in patients with narrow-angle glaucoma, prostatic hyperplasia, or bladder neck obstruction.

Drug-Drug Interaction: Trimium Transhaler may interact with bronchodilators (albuterol), steroids (prednisone), diuretics (furosemide, amiloride), pain killers (aspirin), antibiotics (azithromycin), antidepressants (duloxetine), heart-related medicines (metoprolol), antifungals (itraconazole, voriconazole, posaconazole, ketoconazole), HIV/AIDS drugs (ritonavir), mono-amino oxidase inhibitors (phenelzine),

Drug-Food Interaction: Trimium Transhaler may interact with grapefruit and grapefruit juice. Therefore, avoid grapefruit or its juice with Trimium Transhaler as it may lead to severe adverse effects.

Drug-Disease Interaction: If you have high blood pressure, diabetes, hypokalaemia (low potassium levels in the blood), glaucoma, cataracts, osteoporosis (weak bones), epilepsy, immune system problems, chickenpox, measles, thyroid, lung, heart, liver, or adrenal gland problems, prostatic hyperplasia or bladder neck obstruction, tuberculosis, inform your doctor before taking Trimium Transhaler.

• ALBUTEROL
• PREDNISONE
• FUROSEMIDE
• AMILORIDE
• ASPIRIN
• AZITHROMYCIN
• DULOXETINE
• METOPROLOL
• KETOCONAZOLE
• RITONAVIR
• PHENELZINE
• POSACONAZOLE
• ITRACONAZOLE
• VORICONAZOLE

• Eat a healthy diet and exercise regularly to strengthen your breathing muscles and boost your immune system.
• Avoid foods such as cabbage, beans, garlic, onions, shrimp, pickled food, dried fruits, fried foods, carbonated drinks, wine, bottled lemon, and lime juice as it may worsen asthma symptoms.
• Do meditation, deep breathing, regular exercise, and try progressive muscle relaxation techniques to get relief from stress and reduce the risk of an asthma attack.
• Quit smoking as it may reduce the effectiveness of the Trimium Transhaler and irritate the lungs worsening breathing problems.
• Learning breathing exercises will help you move more air in and out of your lungs.
• Limit alcohol intake.

• You are advised to rinse your mouth with water after each dose of Trimium Transhaler because it not only removes the taste of medicine inhaled but also helps to avoid fungal infections (oral thrush) in the mouth and throat. After rinsing your mouth thoroughly, you may drink water, milk, or any liquids.
• Your doctor may advise regular monitoring of potassium, as the use of Trimium Transhaler may affect the body's potassium levels.

Asthma: It is a chronic (long-term) respiratory condition in which airways narrow, swell, and produce extra mucus leading to difficulty in breathing. The symptoms of asthma include wheezing (whistling sound while breathing), shortness of breath, chest tightness, and cough, especially at night. The symptoms of mild persistent asthma may occur more than 2 times a week and up to 4 nights in a month, whereas, in the case of severe persistent asthma, the symptoms occur several times every day and most nights. The treatment for asthma includes medication, breathing exercises, and self-care.

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath, or wheezing (whistle sound while breathing).