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About Trixide-H Tablet
Trixide-H Tablet is a combination medicine used to treat moderate to severe depression associated with moderate to severe anxiety. Depression is a mood disorder characterised by sadness, unhappiness, anger, hopelessness or loss. Anxiety is a mental health disorder characterised by feelings of anxiety, worry or fear that are strong enough to interfere with one’s daily activities. Anxiety and depression can occur at the same time.
Trixide-H Tablet is a combination of two drugs: Amitriptyline (tricyclic anti-depressant) and Chlordiazepoxide (benzodiazepine anxiolytic). Amitriptyline works by affecting certain chemical messengers in the brain that communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.
You are advised to take Trixide-H Tablet only for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, drowsiness, dry mouth, constipation, blurred vision and bloating. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Do not take Trixide-H Tablet if you are pregnant as it may cause birth defects. Consult your doctor before taking Trixide-H Tablet if you are breastfeeding. Avoid driving or operating machinery as Trixide-H Tablet causes sleepiness, dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with Trixide-H Tablet as it could lead to increased drowsiness and dizziness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.
Uses of Trixide-H Tablet

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Key Benefits
Trixide-H Tablet is a combination of two drugs: Amitriptyline and Chlordiazepoxide. Trixide-H Tablet is used to treat moderate to severe depression and anxiety. Amitriptyline is a tricyclic anti-depressant that affects certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood treats depression. Chlordiazepoxide is a benzodiazepine anxiolytic that works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain. Trixide-H Tablet has a calming effect on various functions of the brain. Thereby, Trixide-H Tablet helps in treating anxiety and depression.
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Drug Warnings
Do not take Trixide-H Tablet if you are allergic to any of its contents, if you recently had a heart attack or heart problems, are taking monoamine oxidase inhibitors (MAOI). Do not take opioids with Trixide-H Tablet as it may result in increased sedation, depression, coma and death. Trixide-H Tablet should not be taken for longer durations as it may cause physical dependence. Inform your doctor before taking Trixide-H Tablet if you have bipolar disorder, eye problems, urination problems, seizures, thyroid problems, kidney or liver problems or if you are due to have any surgery. Consult your doctor immediately if you have suicidal thoughts, such as killing or harming yourself. Talk to your doctor before taking Trixide-H Tablet if you have a history of drug abuse, addiction or alcohol abuse as Trixide-H Tablet may cause dependence. Do not take Trixide-H Tablet if you are pregnant, as it may cause birth defects. Consult your doctor before taking Trixide-H Tablet if you are breastfeeding. Avoid driving or operating machinery as Trixide-H Tablet causes sleepiness, dizziness and might impair thinking and motor skills. Avoid consuming alcohol along with Trixide-H Tablet as it could lead to increased drowsiness and dizziness. Trixide-H Tablet should not be given to children as safety and effectiveness have not been established.
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Special Advise
Trixide-H Tablet contains Amitriptyline and Chlordiazepoxide. Amitriptyline works by affecting certain chemical messengers (serotonin and/or norepinephrine) in the brain, which communicate between brain cells, thereby regulating mood and treating depression. Chlordiazepoxide works by increasing the action of a chemical messenger called GABA. This helps suppress the excessive and abnormal activity of the nerve cells in the brain.
Trixide-H Tablet may cause weight gain due to increased appetite. Eat a healthy diet and exercise regularly to maintain a healthy weight.
Do not discontinue Trixide-H Tablet without consulting your doctor, as it could cause withdrawal symptoms. To treat your condition effectually, continue taking Trixide-H Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Trixide-H Tablet .
Dry mouth could be a side-effect of Trixide-H Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Constipation might occur as a side-effect of Trixide-H Tablet . Drink plenty of fluids and eat fibre-rich food if you experience constipation. Consult your doctor if you experience severe constipation.
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