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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Hetero Healthcare Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Trustiva Tablet

Trustiva Tablet belongs to the class of medicines called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.

Trustiva Tablet contains Emtricitabine, Tenofovir Disoproxil Fumarate and Efavirenz. Efavirenz is a non-nucleoside reverse transcriptase inhibitor, Emtricitabine is a nucleoside reverse transcriptase inhibitor, and Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme production, which is necessary for the multiplication of the viruses. This effect helps to inhibit viral replication.

You should take this medicine exactly as prescribed by the doctor. The common side-effects of Trustiva Tablet are dizziness, headache, diarrhoea, nausea, vomiting, rashes (red spots or blotches, sometimes with blistering and swelling of the skin), and feeling weak. These side effects usually resolve without requiring any medical attention. However, if any of these side effects persist or worsen, inform your doctor immediately.

Trustiva Tablet is not recommended to take Trustiva Tablet if you are allergic to any contents of it. Trustiva Tablet is not recommended for use in lactating mothers, children and adolescents under 18 years of age. Trustiva Tablet may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy. Consumption of alcohol may increase the risk of side effects; therefore, avoid alcohol consumption.

Uses of Trustiva Tablet

HIV infection

Directions for Use

Trustiva Tablet should be swallowed as a whole with a glass of water. Do not crush, chew, or break it. It should be taken on an empty stomach 1 hour before or 2 hours after a meal, preferably at bedtime. Your doctor will prescribe the dose and duration based on your health condition.

Medicinal Benefits

Trustiva Tablet belongs to the group of medicines called antiretroviral therapy. Trustiva Tablet contains Emtricitabine, Tenofovir Disoproxil Fumarate and Efavirenz. Trustiva Tablet works by inhibiting the reverse transcriptase enzyme production, which is necessary to multiply the viruses. This effect helps to inhibit viral replication and treats HIV infection.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Trustiva Tablet should be used with caution in patients with mental illness, fits, and liver diseases. If you notice any signs of infection, inform your doctor immediately. Autoimmune diseases (immune cells attack healthy body tissue) may occur months after the start of the treatment. Inform your doctor if you notice any signs such as muscle weakness, weakness in the hands and feet, palpitations (pounding heart), and tremors. Trustiva Tablet may cause osteonecrosis (death of bone tissue due to a decrease in blood supply to the bone) in some patients. The risk of this disease depends on factors such as length of antiretroviral therapy, alcohol use, steroid use, body mass index (BMI), and immunity. Inform your doctor if you notice joint pain, stiffness, and difficulty in movement, as these symptoms may indicate osteonecrosis.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Trustiva Tablet:
When Trustiva Tablet is taken with Ranolazine, it can lower the levels of Ranolazine.

How to manage the interaction:
Taking Ranolazine with Trustiva Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Trustiva Tablet:
Coadministration of Voriconazole with Trustiva Tablet can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Voriconazole with Trustiva Tablet can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.
EfavirenzGrepafloxacin
Critical
How does the drug interact with Trustiva Tablet:
Taking Trustiva Tablet with Grepafloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Trustiva Tablet with Grepafloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trustiva Tablet:
Using ziprasidone together with Trustiva Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Trustiva Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trustiva Tablet:
Using carbamazepine together with Trustiva Tablet may reduce the effect of carbamazepine.

How to manage the interaction:
Taking Trustiva Tablet with Carbamazepine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
EfavirenzErgometrine
Critical
How does the drug interact with Trustiva Tablet:
When Trustiva Tablet is taken with Ergometrine, the level of Ergometrine in the body can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ergometrine with Trustiva Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, ringing of the ears, chest pain, palpitation, or irregular heartbeats contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzRilpivirine
Critical
How does the drug interact with Trustiva Tablet:
Taking Rilpivirine with Trustiva Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Rilpivirine with Trustiva Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trustiva Tablet:
Taking Trustiva Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Trustiva Tablet with Thioridazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzBepridil
Critical
How does the drug interact with Trustiva Tablet:
Taking Bepridil with Trustiva Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Bepridil with Trustiva Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trustiva Tablet:
Taking Trustiva Tablet and Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Trustiva Tablet and Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy and balanced diet. Consume vitamin and nutrient-rich food such as vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry, or seafood.
  • Eat bland and low-fat foods, and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with your family or doing whatever makes you happy.
  • Drink more fluids and avoid alcoholic beverages to prevent dehydration.
  • Make sure you sleep at least 8 hours a day.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Trustiva Tablet works by inhibiting the reverse transcriptase enzyme production, which is necessary for the production of viruses. This effect helps to inhibit viral replication and treats HIV infection.

Trustiva Tablet is not recommended for patients with severe liver disease, moderate to severe kidney disease, or heart conditions such as prolonged QT interval, which increases the risk of severe heart rhythm problems, family history of heart problems, and low electrolyte levels.

Trustiva Tablet doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.

Trustiva Tablet may cause dizziness, drowsiness, difficulty sleeping, or difficulty concentrating in the first 1-2 days of treatment, and these symptoms generally go away after the first 2-4weeks. Therefore, avoid driving or operating machinery unless you are alert.

Drug-Drug Interactions Checker List

  • ASTEMIZOLE
  • BEPRIDIL
  • CISAPRIDE
  • ELBASVIR
  • GRAZOPREVIR
  • ERGOTAMINE
  • DIHYDROERGOTAMINE
  • ERGONOVINE
  • PIMOZIDE
  • IMIPRAMINE
  • CLOMIPRAMINE
  • HYPERICUM PERFORATUM
  • VORICONAZOLE
  • FLECAINIDE
  • METOPROLOL
  • IMIDAZOLE
  • METHADONE

Special Advise

  • You may still develop infections or other illnesses associated with HIV infection or AIDS. So, people taking Trustiva Tablet should be carefully monitored throughout the treatment.
  • You can still infect other people while taking Trustiva Tablet . So, use necessary precautions to avoid infecting others.
  • Do not stop taking the medicine unless advised by the doctor. This is because the virus gets multiplied and becomes harder to treat if you stop taking the medication for a short time. 
  • Women of childbearing potential must use effective contraception while using Trustiva Tablet and for 12 weeks after stopping the treatment.
  • Trustiva Tablet may affect kidney function, so monitoring kidney function while using this medicine is advised.
  • Trustiva Tablet may decrease phosphate levels in the blood. It may also increase creatine kinase levels in the blood resulting in muscle pain and weakness. Regular monitoring of phosphate levels and creatine kinase levels is advised.

Disease/Condition Glossary

HIV infection: HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other conditions or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. This condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure. However, it can be controlled by treating it with antiretroviral agents.

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