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  3. Trypentin-At Tab 10'S

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Ariaan Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Trypentin-At Tab

Trypentin-At Tab is a combination medicine indicated for the management of neuropathic pain. Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to damaged sensory nerves. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).
 
Trypentin-At Tab is a combination of two drugs: Gabapentin (anti-convulsant) and Amitriptyline (tricyclic antidepressant). Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain. Amitriptyline works by increasing the serotonin and noradrenaline (natural substances) levels in the brain, thereby preventing the movement of pain signals in the brain. Together, Trypentin-At Tab helps in providing relief from neuropathic pain.
 
You are advised to take Trypentin-At Tab for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as dizziness, sleepiness, tiredness, headache, nausea, vomiting, blurred vision, and dry mouth. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Trypentin-At Tab may cause drowsiness and dizziness, so drive only if you are alert. Please consult your doctor if you have any concerns regarding the usage of Trypentin-At Tab in children. Avoid consuming alcohol along with Trypentin-At Tab as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Trypentin-At Tab

Neuropathic pain

Directions for Use

Take Trypentin-At Tab with or without food. Swallow Trypentin-At Tab as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Trypentin-At Tab is a combination of two drugs: Gabapentin and Amitriptyline. Gabapentin belongs to a class of drugs called anti-convulsants whereas Amitriptyline belongs to tricyclic antidepressants. Trypentin-At Tab is used to treat neuropathic pain. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps relieve nerve pain. Amitriptyline works by increasing the level of chemical messengers such as noradrenaline and serotonin, thereby preventing the movement of pain signals in the brain. Together, Trypentin-At Tab helps in providing relief from neuropathic pain.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Trypentin-At Tab if you are allergic to any of its contents; if you recently had a heart attack, if you have heart rhythm problems, severe liver disease or if you are taking monoamine oxidase inhibitors (MAOI) or have taken them in the last 14days. Inform your doctor if you have/had heart, kidney or liver problems, nervous system disorders, respiratory disorders, or muscle weakness. Consult your doctor if you are pregnant or breastfeeding. Trypentin-At Tab may cause drowsiness, dizziness and blurred vision, so drive only if you are alert. Avoid consuming alcohol along with Trypentin-At Tab as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Trypentin-At Tab:
Combining Methylene blue with Trypentin-At Tab can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Methylene blue and Trypentin-At Tab together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Trypentin-At Tab. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trypentin-At Tab:
Combining Trypentin-At Tab and Pimozide may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Trypentin-At Tab with Pimozide may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Trypentin-At Tab:
Trypentin-At Tab and Thioridazine can enhance each other's effects when used together.

How to manage the interaction:
Although using Trypentin-At Tab and Thioridazine together can cause an interaction, they can be used if prescribed by a doctor. If you have extreme sleepiness, confusion, anxiety, vomiting, vision problems, feeling hot or cold, sweating, muscle stiffness, fainting, fits, or coma, seek medical help. Do not discontinue any medications without consulting a doctor.
AmitriptylineGrepafloxacin
Critical
How does the drug interact with Trypentin-At Tab:
Combining Trypentin-At Tab and Grepafloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Trypentin-At Tab with Grepafloxacin may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Grepafloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.
AmitriptylineSaquinavir
Critical
How does the drug interact with Trypentin-At Tab:
Combining Trypentin-At Tab and Saquinavir may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Trypentin-At Tab with Saquinavir may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Trypentin-At Tab:
Taking Linezolid with Trypentin-At Tab can increase the risk of serotonin syndrome (increased serotonin hormone).

How to manage the interaction:
Although using Linezolid and Trypentin-At Tab together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Trypentin-At Tab. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Trypentin-At Tab:
Using Trypentin-At Tab together with Safinamide can increase the risk of serotonin syndrome (A condition resulting from the accumulation of high levels of serotonin in the body. Serotonin is especially a mood stabilizer).

How to manage the interaction:
Although using Safinamide and Trypentin-At Tab together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have symptoms such as confusion, hallucination, fits, blood pressure alteration, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, pain in the muscles or stiffness, incoordination, stomach cramps, nausea, vomiting, and diarrhea. Inform a doctor if you have recently taken Trypentin-At Tab. Do not discontinue any medications without consulting a doctor.
Critical
How does the drug interact with Trypentin-At Tab:
Combining Trypentin-At Tab and Bepridil may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Trypentin-At Tab with Bepridil may result in an interaction, it can be used if a doctor recommends it. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Trypentin-At Tab:
Coadministration of Trypentin-At Tab and Cisapride may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Trypentin-At Tab with Cisapride may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Trypentin-At Tab:
Combining Trypentin-At Tab and Sparfloxacin may increase the risk of irregular heartbeat.

How to manage the interaction:
Although combining Trypentin-At Tab with Sparfloxacin may result in an interaction, it can be used if a doctor recommends it. If you have any heart problems or electrolyte imbalances, you may be susceptible. If you have sudden dizziness, lightheadedness, fainting, or fast or rapid heartbeats during therapy, get emergency medical help. Do not discontinue any medication without consulting a doctor. Note: Sparfloxacin is no longer available in the market. Grepafloxacin should not be combined with any other medications.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include food rich in vitamin B and D in your diet.
  • Include cayenne pepper in your diet as it can help in lowering neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, get plenty of sleep.
  • Try taking a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • ZOLPIDEM
  • DULOXETINE
  • ESCITALOPRAM
  • SERTRALINE
  • HYDROCODONE
  • ACETAMINOPHEN
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CYCLOBENZAPRINE
  • PREGABALIN
  • TOPIRAMATE
  • LEVOTHYROXINE
  • ALPRAZOLAM
  • QUETIAPINE

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is caused due to damaged sensory nerves. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury; the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).

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