Twacal Injection

Twacal Injection is a mineral salt. It is a form of Calcium indicated for pediatric and adult patients to treat several medical conditions caused by low levels of Calcium in the body (hypocalcemia). Hypocalcemia is a treatable condition that happens when the calcium levels in your blood are too low. Many different health conditions can cause hypocalcemia.

Twacal Injection contains Calcium Gluconate, administered to increase Calcium's blood levels in the body, thereby reducing the risk of calcium disorders due to lack of Calcium in the body.

A healthcare professional administers Twacal Injection. Do not self-administer. Sometimes, you may experience local soft tissue inflammation, vasodilation, decreased blood pressure, bradycardia, cardiac arrhythmia, syncope, and cardiac arrest. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Before taking the Twacal Injection, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Twacal Injection should not be used in pregnant and nursing mothers unless clearly necessary. So, inform your doctor if you are a pregnant or nursing mother. Your doctor will weigh the benefits and potential risks before recommending Twacal Injection.

Twacal Injection contains Calcium Gluconate, which is administered to increase blood calcium levels in the body. It treats the body's calcium deficiency (hypocalcemia), thereby reducing the risk of calcium disorders due to low calcium levels. Twacal Injection is also used to treat high potassium levels in the blood, or an overdose of magnesium sulfate (i.e. Epsom salts), sudden severe stomach pain and during heart resuscitation to strengthen the heart muscle. It can be used to prevent abnormal heartbeat (arrhythmia) due to high potassium levels in the blood (severe hyperkalaemia) and helps to restore normal heart function in an emergency (cardiac arrest) if potassium levels in the blood are too high. On the other hand, it can treat lead and fluoride poisoning.

• Local soft tissue inflammation
• Necrosis (the death of body tissue)
• Calcinosis cutis (a group of disorders in which calcium deposits form in the skin)
• Calcification (calcium builds up in body tissue, causing the tissue to harden)
• Extravasation (drug leaks out of the vein and into the surrounding tissue).
• Vasodilation
• Decreased blood pressure
• Bradycardia
• Cardiac arrhythmia
• Syncope
• Cardiac arrest

Before receiving the Twacal Injection, inform your doctor if you are allergic to Twacal Injection or other medicines/foods. If you are pregnant or breastfeeding, think you may be pregnant, or plan to have a baby, ask your healthcare professional for advice before using this medicine. It is recommended not to use Calcium Gluconate Injection if the calcium levels in your blood or urine are above normal levels if you have severe heart disease if you have severe kidney disease, or if you suffer from galactosaemia (disorders of galactose metabolism). So, inform them about your medical conditions and the medications you are currently using to avoid potential interactions.

Drug-Drug Interactions: Twacal Injection may interact with medicines used in the treatment of HIV/AIDS (e.g. cabotegravir, dolutegravir), antibiotics (e.g. ceftriaxone), certain medicines used to treat heart failure (e.g. digitoxin, digoxin).

Drug-Food Interactions: Avoid the consumption of alcohol while taking Twacal Injection.

Drug-Disease Interactions: Inform your doctor if you have Phosphate Imbalance, Arrhythmias (irregular heartbeat), malabsorption (difficulty in the digestion or absorption of nutrients from food), renal dysfunction and sarcoidosis (The growth of tiny collections of inflammatory cells in different parts of the body).

• CABOTEGRAVIR
• DOLUTEGRAVIR
• CEFTRIAXONE
• DIGITOXIN
• DIGOXIN

• Consume a well-balanced and healthy diet.
• Keep your weight under control with a BMI of 19.5-24.9
• Eat low-phosphorus foods such as sourdough bread, corn or rice cereals, cream of wheat, unsalted popcorn and some light-coloured sodas & lemonade.
• Avoid high-phosphorus foods, including bran cereals, oatmeal, nuts, sunflower seeds, whole-grain bread and dark-coloured colas.
• Limit or avoid alcohol consumption.
• Quitting smoking is the best strategy to lower the risk of illness.

• Your doctor may check the amount of electrolytes (e.g. calcium) in your blood at regular intervals.

Hypocalcemia: Hypocalcemia is a curable condition that occurs when the calcium levels in your blood are abnormally low. Hypocalcemia can result from a variety of medical disorders. The most common symptoms of hypocalcemia are paresthesia, muscle spasms, cramps, tetany, circumoral numbness, and convulsions.