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Written By Urvashi Bharti , MBBS
Reviewed By Sunny S , MBBS

About TYROKININ 150MG TABLET 10S

TYROKININ 150MG TABLET 10S belongs to the group of medicine called ‘anti-cancer’ primarily used for lung and pancreatic cancer treatment. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. These abnormal cells do not carry out normal lung cell functions and do not develop into healthy lung tissue. In this disease, cells of the lung grow uncontrollably, and if not detected at an early stage may spread to other body parts, including the brain. Pancreatic cancer is an uncontrolled cancerous growth in the pancreas, usually in the cells that produce insulin.

TYROKININ 150MG TABLET 10S contains 'Erlotinib' that belongs to the group of medicines known as 'kinase inhibitors'. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it prevents the spread of cancerous cells.

Take TYROKININ 150MG TABLET 10S as prescribed by your doctor. You are suggested to take TYROKININ 150MG TABLET 10S as long as your doctor has prescribed it after checking your medical condition.  In some cases, you may experience certain common side-effects such as abdominal pain, bone pain, breathlessness, constipation, cough, diarrhea, edema (swelling), fatigue, fever, infection, muscle pain, nausea, rash, stomatitis (inflammation of the mouth), vomiting, weight loss abnormal blood tests for the liver function. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

To treat your condition effectually, continue taking TYROKININ 150MG TABLET 10S for as long as your doctor has prescribed. Do not take TYROKININ 150MG TABLET 10S if you are pregnant or planning for pregnancy and breastfeeding as TYROKININ 150MG TABLET 10S causes serious congenital disabilities. Older adults are more sensitive to medicine so that they may adjust the dosage according to the condition. While taking TYROKININ 150MG TABLET 10S, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF). Regular blood tests are required to monitor liver function and blood cells in the blood while taking TYROKININ 150MG TABLET 10S. Avoid consuming alcohol along with TYROKININ 150MG TABLET 10S as it could lead to increased dizziness.

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Whats That

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Non returnable*
COD available

Online payment accepted

Composition

ERLOTINIB-150MG

Manufacturer/Marketer

Dr Reddy'S Laboratories Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of TYROKININ 150MG TABLET 10S

Lung cancer, Pancreatic cancer

Medicinal Benefits

TYROKININ 150MG TABLET 10S is prescribed to the patients dealing with nonsmall cell lung cancer and pancreatic cancer. Cancer of this type tends to spread quickly in other parts of the body. TYROKININ 150MG TABLET 10S travel through the bloodstream and effectively destroy cancerous cells of the lung, pancreas, and other body parts. TYROKININ 150MG TABLET 10S contains Erlotinib is a 'tyrosine kinase inhibitor (TKI)' that stops the uncontrolled growth and spread of cancerous cells. It acts by blocking the abnormal protein's action that is responsible for the multiplication of cancerous cells. Whenever a new healthy cell is formed, it undergoes a usual process of maturity. Cancerous cells form new cells more quickly, so TYROKININ 150MG TABLET 10S targets cancerous cells and block the action of Tyrosine kinases enzymes (responsible for causing cancer). It also decreases the blood supply to cancer tumors to slow down the growth of the tumor. In this way, TYROKININ 150MG TABLET 10S stops the production, spread, and growth of cancerous cells in the body. 

Side Effects of TYROKININ 150MG TABLET 10S

  • ​​​​Stomach pain
  • Bone pain
  • Breathlessness
  • Constipation
  • Cough
  • Diarrhea
  • Loss of appetite
  • Edema (swelling)
  • Fatigue
  • Fever
  • Infection
  • Muscle pain
  • Nausea
  • Rash
  • Changes in vision
  • Partial hair loss (by strands, not typically in clumps)
  • Stomatitis (Inflammation of the mouth)
  • Weight loss
  • Abnormal blood tests for the liver function

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take TYROKININ 150MG TABLET 10S if you are allergic to TYROKININ 150MG TABLET 10S or any of its ingredients. While taking TYROKININ 150MG TABLET 10S, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF) while going out as it can lead to a skin rash if you are not using a strong SPF. TYROKININ 150MG TABLET 10S can cause leg swelling and water retention or fluid overload (edema), so if you have unexpected rapid weight gain, please consult your doctor. Do not take TYROKININ 150MG TABLET 10S if you are pregnant or planning to get pregnant and breastfeeding as it could harm the unborn baby. Use effective birth control measures while taking this medication and for at least 1 month after your last dose. TYROKININ 150MG TABLET 10S is not recommended for children and adolescents. You are advised to stop smoking while taking TYROKININ 150MG TABLET 10S as smoking could decrease this medication's effect. TYROKININ 150MG TABLET 10S may make you more susceptible to infections, consult your doctor if you develop any signs of infections, fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.  TYROKININ 150MG TABLET 10S may cause blurry vision and dizziness, so do not drive or operate any machinery which requires concentration. Before undergoing any surgery, it is advised to tell the medical professional who performs the procedure about all the medicines you are taking. 

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

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ErlotinibOmeprazole
Critical
ErlotinibRabeprazole
Critical

Drug-Drug Interactions

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ErlotinibOmeprazole
Critical
How does the drug interact with TYROKININ 150MG TABLET 10S:
Omeprazole can make TYROKININ 150MG TABLET 10S less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Omeprazole and TYROKININ 150MG TABLET 10S together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ErlotinibRabeprazole
Critical
How does the drug interact with TYROKININ 150MG TABLET 10S:
When used in combination with TYROKININ 150MG TABLET 10S, Rabeprazole may prevent the absorption of TYROKININ 150MG TABLET 10S into the circulation, which might make TYROKININ 150MG TABLET 10S less effective in treating cancer.

How to manage the interaction:
Taking Rabeprazole with TYROKININ 150MG TABLET 10S is not recommended as it can result in an interaction, it should be taken only if a doctor has advised it. Do not stop using any medications without consulting a doctor.
ErlotinibRifapentine
Severe
How does the drug interact with TYROKININ 150MG TABLET 10S:
When TYROKININ 150MG TABLET 10S is taken with rifapentine, it reduces the blood levels of TYROKININ 150MG TABLET 10S.

How to manage the interaction:
Although there is a possible interaction between TYROKININ 150MG TABLET 10S and Rifapentine, you can take these medicines together if advised by a doctor. Do not discontinue any medications without first consulting a doctor.
ErlotinibPrimidone
Severe
How does the drug interact with TYROKININ 150MG TABLET 10S:
When TYROKININ 150MG TABLET 10S is taken with primidone, it reduces the blood levels of TYROKININ 150MG TABLET 10S. This can lead to low treatment outcomes.

How to manage the interaction:
Taking TYROKININ 150MG TABLET 10S with Primidone together can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to a doctor.
ErlotinibRanitidine bismuth citrate
Severe
How does the drug interact with TYROKININ 150MG TABLET 10S:
Coadministration of Ranitidine bismuth citrate with TYROKININ 150MG TABLET 10S can interfere with the absorption of TYROKININ 150MG TABLET 10S and reduce its effectiveness.

How to manage the interaction:
Taking Ranitidine bismuth citrate with TYROKININ 150MG TABLET 10S together can result in an interaction, but it can be taken if your doctor has advised it. When taken together, your doctor can recommend other options that won't cause any problems. Do not stop using any medications without talking to a doctor.
ErlotinibTeriflunomide
Severe
How does the drug interact with TYROKININ 150MG TABLET 10S:
Taking TYROKININ 150MG TABLET 10S with Teriflunomide can increase the risk or severity of liver damage.

How to manage the interaction:
Taking TYROKININ 150MG TABLET 10S with Teriflunomide together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ErlotinibLomitapide
Severe
How does the drug interact with TYROKININ 150MG TABLET 10S:
Taking TYROKININ 150MG TABLET 10S and Lomitapide can increase the risk or severity of liver damage.

How to manage the interaction:
Taking TYROKININ 150MG TABLET 10S and Lomitapide is generally avoided as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
ErlotinibRifabutin
Severe
How does the drug interact with TYROKININ 150MG TABLET 10S:
Taking Rifabutin and TYROKININ 150MG TABLET 10S may significantly reduce the blood levels of TYROKININ 150MG TABLET 10S.

How to manage the interaction:
Co-administration of TYROKININ 150MG TABLET 10S with Rifabutin can result in an interaction, but it can be taken if your doctor has advised it. If you experience any unusual symptoms, consult a doctor. Do not stop using any medications without a doctor's advice.
ErlotinibEnzalutamide
Severe
How does the drug interact with TYROKININ 150MG TABLET 10S:
Taking Enzalutamide with TYROKININ 150MG TABLET 10S may decrease the blood levels of TYROKININ 150MG TABLET 10S, which may make TYROKININ 150MG TABLET 10S less effective.

How to manage the interaction:
Although taking Enzalutamide and TYROKININ 150MG TABLET 10S together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
ErlotinibKetoconazole
Severe
How does the drug interact with TYROKININ 150MG TABLET 10S:
TYROKININ 150MG TABLET 10S's effects and blood levels could both be enhanced by ketoconazole.

How to manage the interaction:
Although taking Ketoconazole and TYROKININ 150MG TABLET 10S together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you develop severe or ongoing diarrhea, nausea, vomiting, lack of appetite, skin rash, shortness of breath, cough, or fever, consult a doctor.

Drug-Food Interactions

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ERLOTINIB-150MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ERLOTINIB-150MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Grapefruit juice can increase the absorption of TYROKININ 150MG TABLET 10S which may lead to higher blood levels of TYROKININ 150MG TABLET 10S and possibly increased side effects. Avoid or limit the consumption of Grapefruit juice or Grapefruit while taking TYROKININ 150MG TABLET 10S as it can lead to increased risk or severity of side effects. However, if you notice any Burning, tingling, numbness or pain in the hands, arms, feet, or legs, cough or hoarseness, or severe diarrhea, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • AMLODIPINE
  • METOPROLOL
  • NIFEDIPINE
  • QUINIDINE
  • ATORVASTATIN
  • FLUVASTATIN
  • PRAVASTATIN
  • ROSUVASTATIN
  • SIMVASTATIN
  • CYCLOSPORINE
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • CLARITHROMYCIN
  • RIFAMPICIN
  • CIPROFLOXACIN
  • ITRACONAZOLE
  • VORICONAZOLE
  • KETOCONAZOLE
  • TRIAZOLAM
  • ALPRAZOLAM
  • ESTAZOLAM
  • PRIMIDONE
  • PHENOBARBITAL
  • PHENYTOIN
  • CARBAMAZEPINE
  • SAQUINAVIR
  • RITONAVIR
  • SILDENAFIL
  • OMEPRAZOLE
  • RANITIDINE

Diet & Lifestyle Advise

  • ​​​​​​Physical activity helps in strengthening muscles, reduce fatigue, aids in weight loss, and give strength. Gentle exercises like 20-30 minutes of walking or swimming would be helpful.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and reduce stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting helps in improving your health, mental ability and improves attention.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listen to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing fiber help in better digestion. These include beans, peas, lentils, whole grains,  nuts, and seeds.
  • Avoid smoking and alcohol consumption. 

Habit Forming

No

Special Advise

  • ​​​​​​Regular blood test is required to monitor liver function and blood cells in blood while taking TYROKININ 150MG TABLET 10S.
  • While taking TYROKININ 150MG TABLET 10S, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF) while going out as it can lead to a skin rash if you are not using a strong SPF.
  • Always take it with food and a full glass of water to prevent nausea.
  • TYROKININ 150MG TABLET 10S can cause swelling and water retention, so if you have unexpected rapid weight gain, please consult your doctor. 
  • Do not have immunizations with live vaccines (for mumps, rubella, measles and BCG, yellow fever and shingles or pox chicken) while you’re having treatment and for up to 12 months afterward. 
  • Contact your doctor immediately if you experience any infection signs, including a temperature above 37.5 C or below 36 C.

Author Details

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Disease/Condition Glossary

Lung cancer: It happens when cells in the lung begin to grow in an uncontrolled manner. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Persons who smoke are at high risk of lung cancer. A common symptom of NSCLC is a cough that does not go quickly followed by shortness of breath. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow.

Pancreatic cancer: It is a type of tumor in the pancreas that usually begins in the juice's cells. It is a gland behind your stomach that produces juices that help break down food and the hormones that help control blood sugar levels.

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