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Written By Urvashi Bharti , MBBS
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Synonym

CALCITONIN SALMON

Composition

CALCITONIN-100IU

Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About UNICALCIN 100IU INJECTION 1ML

UNICALCIN 100IU INJECTION 1ML belongs to groups of medications called hypocalcemic agents, used to treat high blood calcium levels (hypercalcemia) and Postmenopausal Osteoporosis. Besides this, it can also help treat complications of Paget's disease. Hypercalcemia is a condition in which the calcium level in your blood is above normal. Postmenopausal osteoporosis is a medical condition that causes thinning and weakening of the bones during/after a menopausal period. Paget’s disease is a chronic disease of bone that disrupts the replacement of old bone tissue with new bone tissue, resulting in the new bone that is abnormally shaped, weak and brittle.

UNICALCIN 100IU INJECTION 1ML contains Calcitonin. It reduces the activity of osteoclasts, which are the cells responsible for bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. As a result, calcitonin's suppression of osteoclasts limits the quantity of calcium released into the blood. Furthermore, it can reduce calcium resorption in the kidneys, resulting in decreased blood calcium levels.

UNICALCIN 100IU INJECTION 1ML will be administered by a qualified healthcare professional. Kindly do not self-administer. In some cases, UNICALCIN 100IU INJECTION 1ML can cause side effects, including injection site reactions, nausea with or without vomiting and flushing of the face or hands. Most of these side effects of UNICALCIN 100IU INJECTION 1ML do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Before taking the UNICALCIN 100IU INJECTION 1ML, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. UNICALCIN 100IU INJECTION 1ML should not be given to children as safety and efficacy have not been established.

Uses of UNICALCIN 100IU INJECTION 1ML

Postmenopausal osteoporosis, Paget’s disease, Hypercalcemia.

Directions for Use

UNICALCIN 100IU INJECTION 1ML will be administrated by a healthcare professional. Do not self-administer.

Medicinal Benefits

UNICALCIN 100IU INJECTION 1ML contains calcitonin, which belongs to groups of medications called hypocalcemic agents and is used to treat high blood calcium levels (hypercalcemia) and Postmenopausal Osteoporosis. On the other hand, it can also help people with Paget's disease of bone. UNICALCIN 100IU INJECTION 1ML reduces the activity of osteoclasts, which are the cells responsible for bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. As a result, calcitonin's suppression of osteoclasts limits the quantity of calcium released into the blood. Furthermore, it can reduce calcium resorption in the kidneys, decreasing blood calcium levels.

Storage

Store in a cool and dry place away from sunlight

Side Effects of UNICALCIN 100IU INJECTION 1ML

  • Injection site reactions
  • Nausea with or without vomiting
  • Flushing of the face or hands

Drug Warnings

Before taking the UNICALCIN 100IU INJECTION 1ML, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. UNICALCIN 100IU INJECTION 1ML should not be given to children as safety and efficacy have not been established. In rare situations, UNICALCIN 100IU INJECTION 1ML may cause major hypersensitivity reactions in individuals receiving Miacalcin injection, including bronchospasm, inflammation of the tongue or throat and anaphylactic shock. If you encounter any of these symptoms, contact your doctor right once.

Drug-Drug Interactions

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calcitonin (salmon synthetic)Etelcalcetide
Severe

Drug-Drug Interactions

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calcitonin (salmon synthetic)Etelcalcetide
Severe
How does the drug interact with Unicalcin 100iu Injection 1ml:
Etelcalcetide may decrease the calcium levels in the blood. Concomitant use with calcitonin may increase the risk of hypocalcemia, or low blood calcium.

How to manage the interaction:
Although there is an interaction, calcitonin can be taken with etelcalcetide if prescribed by the doctor. Consult the prescriber if you notice symptoms of hypocalcemia like numbness or tingling around your mouth, muscle spasms, or mental changes (irritability, depression, psychosis). Do not discontinue using any medication without contacting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should consume calcium and vitamin D in their diet as it helps make stronger bones and avoid everyday osteoporosis dangers.
  • A post-menopausal woman should limit salt intake as it can pose a high risk of losing more bone minerals than other women of the same age.
  • Do regular exercise like weight-bearing exercises which are important for maintaining bone health.
  • Calcium is important for making bones strong. Vitamin D is equally important, which helps to ensure the absorption and retention of calcium in bones, so take food high in calcium and vitamins.

Habit Forming

No

Therapeutic Class

HYPOCALCEMIC AGENTS

UNICALCIN 100IU INJECTION 1ML Substitute

Substitutes safety advice
  • Ostishine Nasal Spray 6 ml

    by Others

    217.35per tablet
  • Calcito-S 100iu Injection 1ml

    by AYUR

    291.60per tablet

Author Details

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Drug-Diseases Interactions

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CALCITONIN-100IUDisorders of mineral metabolism
Moderate
CALCITONIN-100IUDisorders of mineral metabolism
Moderate

Drug-Diseases Interactions

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CALCITONIN-100IUDisorders of mineral metabolism
Moderate
How does the disease interact with Unicalcin 100iu Injection 1ml:
Calcium levels in the serum are reduced . Patients who already have hypocalcemia should use caution when administering calcium to prevent unwanted side effects. It is preferable to address hypocalcemia before beginning medication. A sufficient intake of calcium and vitamin D should be made sure during the course of treatment if calcitonin is used to promote bone mineral density, as in the case of osteoporosis

How to manage the interaction:
Calcitonin may cause hypocalcemic effects. Therefore, it should be administered cautiously to patients with preexisting hypocalcemia, since they may be particularly sensitive to these effects.
CALCITONIN-100IUDisorders of mineral metabolism
Moderate
How does the disease interact with Unicalcin 100iu Injection 1ml:
Prior to beginning medication, hypocalcemia and other abnormalities of mineral metabolism, such as vitamin D deficiency, should be corrected when calcitonin is used to treat osteoporosis. The body must have an adequate quantity of calcium and vitamin D for the necessary increase in bone mineral density to occur. When treating patients with these conditions with calcitonin salmon nasal spray, serum calcium and hypocalcemia symptoms should be kept under close observation. Throughout the course of treatment, it is important to ensure an adequate intake of calcium and vitamin D

How to manage the interaction:
In patients with mineral metabolism disorders, serum calcium and symptoms of hypocalcemia should be monitored during therapy. Appropriate intake of calcium and vitamin D should be ensured throughout the course of treatment.

Drug-Drug Interactions Checker List

  • LITHIUM
  • ETELCALCETIDE
  • FOSCARNET

Special Advise

  • Certain diagnostic tests, like blood tests, measure the calcitonin level in your blood, and bone density scans are used to check bone mineral density (BMD).
  • Clinical monitoring of serum electrolyte concentrations is recommended.

Disease/Condition Glossary

Postmenopausal Osteoporosis: Postmenopausal Osteoporosis is a medical condition that causes thinning and weakening of the bones during/after a menopausal period. The chance of developing Osteoporosis (weak bone) is related to estrogen deficiency. During the menopausal period (45 years of age), the drop in estrogen leads to more bone resorption (osteoclasts; bone breakdown) than formation (osteoblast; new bone formation), resulting in Osteoporosis. In starting days, Osteoporosis does not show any symptoms. However, if proper treatment is not provided, it can lead to broken bones. Initially, the bones don't hurt, and breaks in the spine's bones may go unseen until they cause height loss. In Osteoporosis, bones can break at any time, even during daily activities like lifting or even from minor activities. 

Paget's disease: Paget's disease is a chronic disease of bone that disrupts the replacement of old bone tissue with new bone tissue, resulting in the new bone that is abnormally shaped, weak and brittle. It most commonly occurs in the pelvis, skull, spine, and legs. Symptoms include bone pain, joint pain (especially in the back, hips, and knees), headache, enlargement and bowing of the thighs (femurs) and lower legs (tibias), and enlargement of the skull in the area of the forehead.

Hypercalcemia: Hypercalcemia is when the calcium level in the blood is higher than normal. Too much calcium in the blood can weaken the bones, create kidney stones, and interfere with working the heart and brain. It is usually a result of overactive parathyroid glands. Symptoms include increased thirst and urination, stomach pain, nausea, bone pain, muscle weakness, confusion and fatigue.

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