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  3. UNICALCIN 50IU INJECTION 1ML

Written By Urvashi Bharti , MBBS
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Synonym :

CALCITONIN SALMON

Composition :

CALCITONIN-50IU

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About UNICALCIN 50IU INJECTION 1ML

UNICALCIN 50IU INJECTION 1ML belongs to groups of medications called hypocalcemic agents, used to treat high blood calcium levels (hypercalcemia) and Postmenopausal Osteoporosis. Besides this, it can also help treat complications of Paget's disease. Hypercalcemia is a condition in which the calcium level in your blood is above normal. Postmenopausal osteoporosis is a medical condition that causes thinning and weakening of the bones during/after a menopausal period. Paget’s disease is a chronic disease of bone that disrupts the replacement of old bone tissue with new bone tissue, resulting in the new bone that is abnormally shaped, weak and brittle.

UNICALCIN 50IU INJECTION 1ML contains Calcitonin. It reduces the activity of osteoclasts, which are the cells responsible for bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. As a result, calcitonin's suppression of osteoclasts limits the quantity of calcium released into the blood. Furthermore, it can reduce calcium resorption in the kidneys, resulting in decreased blood calcium levels.

UNICALCIN 50IU INJECTION 1ML will be administered by a qualified healthcare professional. Kindly do not self-administer. In some cases, UNICALCIN 50IU INJECTION 1ML can cause side effects, including injection site reactions, nausea with or without vomiting and flushing of the face or hands. Most of these side effects of UNICALCIN 50IU INJECTION 1ML do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Before taking the UNICALCIN 50IU INJECTION 1ML, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. UNICALCIN 50IU INJECTION 1ML should not be given to children as safety and efficacy have not been established.

Uses of UNICALCIN 50IU INJECTION 1ML

Postmenopausal osteoporosis, Paget’s disease, Hypercalcemia.

Directions for Use

UNICALCIN 50IU INJECTION 1ML will be administrated by a healthcare professional. Do not self-administer.

Medicinal Benefits

UNICALCIN 50IU INJECTION 1ML contains calcitonin, which belongs to groups of medications called hypocalcemic agents and is used to treat high blood calcium levels (hypercalcemia) and Postmenopausal Osteoporosis. On the other hand, it can also help people with Paget's disease of bone. UNICALCIN 50IU INJECTION 1ML reduces the activity of osteoclasts, which are the cells responsible for bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. As a result, calcitonin's suppression of osteoclasts limits the quantity of calcium released into the blood. Furthermore, it can reduce calcium resorption in the kidneys, decreasing blood calcium levels.

Storage

Store in a cool and dry place away from sunlight
Side effects of Unicalcin 50iu Injection 1ml
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Before taking the UNICALCIN 50IU INJECTION 1ML, let your doctor know about all your medical conditions, sensitivities, and all medications you are using. And also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. UNICALCIN 50IU INJECTION 1ML should not be given to children as safety and efficacy have not been established. In rare situations, UNICALCIN 50IU INJECTION 1ML may cause major hypersensitivity reactions in individuals receiving Miacalcin injection, including bronchospasm, inflammation of the tongue or throat and anaphylactic shock. If you encounter any of these symptoms, contact your doctor right once.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Unicalcin 50iu Injection 1ml:
Etelcalcetide may decrease the calcium levels in the blood. Concomitant use with calcitonin may increase the risk of hypocalcemia, or low blood calcium.

How to manage the interaction:
Although there is an interaction, calcitonin can be taken with etelcalcetide if prescribed by the doctor. Consult the prescriber if you notice symptoms of hypocalcemia like numbness or tingling around your mouth, muscle spasms, or mental changes (irritability, depression, psychosis). Do not discontinue using any medication without contacting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A person should consume calcium and vitamin D in their diet as it helps make stronger bones and avoid everyday osteoporosis dangers.
  • A post-menopausal woman should limit salt intake as it can pose a high risk of losing more bone minerals than other women of the same age.
  • Do regular exercise like weight-bearing exercises which are important for maintaining bone health.
  • Calcium is important for making bones strong. Vitamin D is equally important, which helps to ensure the absorption and retention of calcium in bones, so take food high in calcium and vitamins.

Habit Forming

No

Therapeutic Class

HYPOCALCEMIC AGENTS

Author Details

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Drug-Diseases Interactions

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CALCITONIN-50IUDisorders of mineral metabolism
Moderate
CALCITONIN-50IUDisorders of mineral metabolism
Moderate

Drug-Diseases Interactions

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CALCITONIN-50IUDisorders of mineral metabolism
Moderate
How does the disease interact with Unicalcin 50iu Injection 1ml:
Calcium levels in the serum are reduced . Patients who already have hypocalcemia should use caution when administering calcium to prevent unwanted side effects. It is preferable to address hypocalcemia before beginning medication. A sufficient intake of calcium and vitamin D should be made sure during the course of treatment if calcitonin is used to promote bone mineral density, as in the case of osteoporosis

How to manage the interaction:
Calcitonin may cause hypocalcemic effects. Therefore, it should be administered cautiously to patients with preexisting hypocalcemia, since they may be particularly sensitive to these effects.
CALCITONIN-50IUDisorders of mineral metabolism
Moderate
How does the disease interact with Unicalcin 50iu Injection 1ml:
Prior to beginning medication, hypocalcemia and other abnormalities of mineral metabolism, such as vitamin D deficiency, should be corrected when calcitonin is used to treat osteoporosis. The body must have an adequate quantity of calcium and vitamin D for the necessary increase in bone mineral density to occur. When treating patients with these conditions with calcitonin salmon nasal spray, serum calcium and hypocalcemia symptoms should be kept under close observation. Throughout the course of treatment, it is important to ensure an adequate intake of calcium and vitamin D

How to manage the interaction:
In patients with mineral metabolism disorders, serum calcium and symptoms of hypocalcemia should be monitored during therapy. Appropriate intake of calcium and vitamin D should be ensured throughout the course of treatment.

FAQs

UNICALCIN 50IU INJECTION 1ML contains Calcitonin. It reduces the activity of osteoclasts, which are the cells responsible for bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. As a result, calcitonin's suppression of osteoclasts limits the quantity of calcium released into the blood. Furthermore, it can reduce calcium resorption in the kidneys, resulting in decreased blood calcium levels.

If you have osteoporosis, avoid smoking, or try to quit. Smoking can reduce bone mineral density and increases the risk of fractures.

UNICALCIN 50IU INJECTION 1ML contains Calcitonin, a hormone that regulates the calcium level in the blood. This hormone helps in bone formation and also helps the body to reverse bone loss. Due to this, the number of cells that damages bones becomes comparatively less. Hence, the bone damage is halted. Using UNICALCIN 50IU INJECTION 1ML can increase bone formation by activation of the bone-forming cells.

Persons whose age is more than 45 years have low estrogen levels, females reaching menopause, too much consumption of alcohol, tobacco or caffeine, use of glucocorticoids and lack of calcium and vitamin D in foods are some of the factors that can increase the risk of osteoporosis.

Yes, UNICALCIN 50IU INJECTION 1ML is used together with calcium and vitamin D to treat bone loss in women with postmenopausal osteoporosis who have been postmenopausal for at least five years. UNICALCIN 50IU INJECTION 1ML inhibits the function of osteoclasts (bone breakdown), reducing bone resorption; thus, combining calcium and calcitonin could result in a positive bone balance.

Drug-Drug Interactions Checker List

  • LITHIUM
  • ETELCALCETIDE
  • FOSCARNET

Special Advise

  • Certain diagnostic tests, like blood tests, measure the calcitonin level in your blood, and bone density scans are used to check bone mineral density (BMD).
  • Clinical monitoring of serum electrolyte concentrations is recommended.

Disease/Condition Glossary

Postmenopausal Osteoporosis: Postmenopausal Osteoporosis is a medical condition that causes thinning and weakening of the bones during/after a menopausal period. The chance of developing Osteoporosis (weak bone) is related to estrogen deficiency. During the menopausal period (45 years of age), the drop in estrogen leads to more bone resorption (osteoclasts; bone breakdown) than formation (osteoblast; new bone formation), resulting in Osteoporosis. In starting days, Osteoporosis does not show any symptoms. However, if proper treatment is not provided, it can lead to broken bones. Initially, the bones don't hurt, and breaks in the spine's bones may go unseen until they cause height loss. In Osteoporosis, bones can break at any time, even during daily activities like lifting or even from minor activities. 

Paget's disease: Paget's disease is a chronic disease of bone that disrupts the replacement of old bone tissue with new bone tissue, resulting in the new bone that is abnormally shaped, weak and brittle. It most commonly occurs in the pelvis, skull, spine, and legs. Symptoms include bone pain, joint pain (especially in the back, hips, and knees), headache, enlargement and bowing of the thighs (femurs) and lower legs (tibias), and enlargement of the skull in the area of the forehead.

Hypercalcemia: Hypercalcemia is when the calcium level in the blood is higher than normal. Too much calcium in the blood can weaken the bones, create kidney stones, and interfere with working the heart and brain. It is usually a result of overactive parathyroid glands. Symptoms include increased thirst and urination, stomach pain, nausea, bone pain, muscle weakness, confusion and fatigue.

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