Unidol 100mg Injection 2 ml

Written By Veda Maddala , M Pharmacy

Reviewed By Santoshini Reddy G , M Pharmacy

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MRP ₹20.8

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Whats That

About Unidol 100mg Injection 2 ml

Unidol 100mg Injection 2 ml belongs to a class of medicines called opioid analgesics (pain killers). Unidol 100mg Injection 2 ml is primarily used in the treatment of moderate to severe pain. Pain is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body).

Unidol 100mg Injection 2 ml contains Tramadol that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibits the transmission of pain signals from nerves to brain. Also, Unidol 100mg Injection 2 ml improves the effect of serotonin and noradrenaline (chemical messengers in brain and spinal cord) and helps in relieving pain.

Unidol 100mg Injection 2 ml will be administered by a healthcare professional; do not self-administer. In some cases, you may experience nausea, dizziness, headache, vomiting, dry mouth, drowsiness, constipation or sweating. Most of these side effects of Unidol 100mg Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are known to be allergic to Unidol 100mg Injection 2 ml or any other medicines, please tell your doctor. Unidol 100mg Injection 2 ml is not recommended for children suffering from breathing problems. If you are pregnant or breastfeeding or have history of fits, please inform your doctor before taking Unidol 100mg Injection 2 ml. Do not consume alcohol with Unidol 100mg Injection 2 ml as it may increase the risk of side effects. Avoid frequent or high doses as it may lead to addiction.

Uses of Unidol 100mg Injection 2 ml

Moderate to severe pain

Directions for Use

Unidol 100mg Injection 2 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Unidol 100mg Injection 2 ml is a pain killer that works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibits the transmission of pain signals from nerves to the brain. Also, Unidol 100mg Injection 2 ml improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain. Unidol 100mg Injection 2 ml is used to relieve pain after surgery, pain caused by an injury or illness.

Storage

Keep Unidol 100mg Injection 2 ml out of reach and sight of children.

Side effects of Unidol 100mg Injection 2 ml

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Constipation

Here are the steps to cope with constipation as a side effect of medication:

Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Abnormal liver function test

High levels of liver enzymes need immediate medical attention.
Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
Regularly do strengthening exercises to control your cholesterol levels.
Avoid drinking alcohol as it can affect your liver.
Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
Practice yoga and meditation to improve liver functioning and overall health.

Kidney Problem

Limit processed foods and eat more vegetables and fruits.
Exercise at least 30 minutes every day.
Maintain a healthy weight.
Quit smoking as it can worsen kidney damage.
Control your blood pressure and blood glucose.
Limit salt intake and alcohol consumption.

Itching

Here are the few steps for dealing with itching caused by drug use:

Report the itching to your doctor immediately; they may need to change your medication or dosage.
Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
Try not to scratch, as this can worsen the itching and irritate your skin.
If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Anemia

Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
Consume vitamin C-rich foods as they aid iron absorption.
Limit tea, cocoa, and coffee as these can slow iron absorption.
Exercise regularly; however, do not overdo it.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Drug Warnings

If you are allergic to Tramadol or any other medicines, please tell your doctor. Unidol 100mg Injection 2 ml is not recommended for children suffering from breathing problems as it may worsen the symptoms of tramadol toxicity. If you are pregnant or breastfeeding or have a history of fits, please inform your doctor before taking Unidol 100mg Injection 2 ml. Do not consume alcohol with Unidol 100mg Injection 2 ml as it may increase the risk of side effects. Unidol 100mg Injection 2 ml may cause withdrawal symptoms if stopped abruptly. Avoid frequent or high doses as it may lead to addiction.

Drug-Drug Interactions

DiclofenacMeloxicam

Critical

DiclofenacKetorolac

Severe

Drug-Drug Interactions

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DiclofenacMeloxicam

Critical

How does the drug interact with Unidol 100mg Injection 2 ml:
Co-administration of Unidol 100mg Injection 2 ml with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Unidol 100mg Injection 2 ml is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.

DiclofenacKetorolac

Severe

How does the drug interact with Unidol 100mg Injection 2 ml:
Coadministration of Unidol 100mg Injection 2 ml and Ketorolac can increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding and ulceration.

How to manage the interaction:
Co-administration of Unidol 100mg Injection 2 ml and Ketorolac can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

DiclofenacLeflunomide

Severe

How does the drug interact with Unidol 100mg Injection 2 ml:
Co administration of Unidol 100mg Injection 2 ml with Leflunomide may result in liver problems.

How to manage the interaction:
Co-administration of Unidol 100mg Injection 2 ml and Leflunomide can lead to an interaction; it can be taken if advised by your doctor. However, if you have a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, or yellowing of the skin or eyes. Do not stop using any medication without consulting your doctor.

DiclofenacFondaparinux

Severe

How does the drug interact with Unidol 100mg Injection 2 ml:
Coadministration of Unidol 100mg Injection 2 ml with fondaparinux may increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Unidol 100mg Injection 2 ml and Fondaparinux when taken together, but they can be taken together if your doctor has prescribed them. However, if you experience bleeding, severe back pain, dizziness, black or red stools, severe headache, weakness, and vomiting contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

DiclofenacOxaprozin

Severe

How does the drug interact with Unidol 100mg Injection 2 ml:
Taking Unidol 100mg Injection 2 ml and oxaprozin can increase the risk of side effects.

How to manage the interaction:
Co-administration of Unidol 100mg Injection 2 ml and oxaprozin can lead to an interaction; it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult your doctor immediately. Do not stop using any medications without a doctor's advice.

DiclofenacSirolimus

Severe

How does the drug interact with Unidol 100mg Injection 2 ml:
Co-administration of Unidol 100mg Injection 2 ml with Sirolimus may increase the risk or severity of kidney problems.

How to manage the interaction:
Co-administration of Unidol 100mg Injection 2 ml and Sirolimus can lead to an interaction, but it can be taken if advised by a doctor. However, consult a doctor if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

DiclofenacVorapaxar

Severe

How does the drug interact with Unidol 100mg Injection 2 ml:
Taking Unidol 100mg Injection 2 ml with Vorapaxar can increase the risk of bleeding complications.

How to manage the interaction:
There may be a possible interaction between Unidol 100mg Injection 2 ml and Vorapaxar, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headaches. Do not discontinue any medications without consulting your doctor.

DiclofenacBromfenac

Severe

How does the drug interact with Unidol 100mg Injection 2 ml:
Taking Unidol 100mg Injection 2 ml with bromfenac will have an additive effect and may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.

How to manage the interaction:
There may be possible interaction between Unidol 100mg Injection 2 ml and bromfenac but you can take it if prescribed by a doctor. Consult your doctor if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. Do not stop using any medications without first talking to your doctor.

DiclofenacDabigatran etexilate

Severe

How does the drug interact with Unidol 100mg Injection 2 ml:
Concomitant use of Unidol 100mg Injection 2 ml with dabigatran may increase the risk of stomach bleeding.

How to manage the interaction:
Taking Unidol 100mg Injection 2 ml with dabigatran together possibly results in an interaction, it can be taken if your doctor has advised it. You should consult a doctor immediately if you experience any unusual bleeding or bruising or have other signs and symptoms of bleeding such as dizziness, light headedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache and weakness. Do not stop using any medications without first talking to your doctor.

DiclofenacDalteparin

Severe

How does the drug interact with Unidol 100mg Injection 2 ml:
Co-administration use of Unidol 100mg Injection 2 ml with Dalteparin may increase the risk of bleeding complications.

How to manage the interaction:
Although taking Dalteparin with Unidol 100mg Injection 2 ml may possibly lead to an interaction, they can be taken if a doctor prescribes it. Consult a doctor if you have any symptoms including dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that resembles coffee grounds, severe headache, and weakness. Without consulting a doctor, never stop taking any medication.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Do regular exercises such as swimming or walking.
Drink plenty of water while taking Unidol 100mg Injection 2 ml to avoid dry mouth.
Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking Unidol 100mg Injection 2 ml.
Avoid consumption of alcohol and quit smoking.

Side Effects of Unidol 100mg Injection 2 ml

Nausea
Dizziness
Headache
Vomiting
Dry mouth
Drowsiness
Constipation
Sweating

Habit Forming

Yes

Therapeutic Class

NARCOTIC (OPIOID) ANALGESIC

Unidol 100mg Injection 2 ml Substitute

Unidol 50Mg/1Ml Inj

by AYUR

₹9.54per tablet

Author Details

Written By

Veda Maddala

M Pharmacy

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:45 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Unidol 100mg Injection 2 ml work?

Unidol 100mg Injection 2 ml works by mimicking the action of endorphins (pain-reducing chemicals) in the brain and spinal cord. Thereby, inhibiting the transmission of pain signals from nerves to the brain. Also, Unidol 100mg Injection 2 ml improves the effect of serotonin and noradrenaline (chemical messengers in the brain and spinal cord) and helps in relieving pain.

Does Unidol 100mg Injection 2 ml cause withdrawal symptoms?

Unidol 100mg Injection 2 ml may cause withdrawal symptoms such as irritability, anxiety, restlessness, difficulty in sleeping, palpitations (feeling your heartbeat), feeling sick, shivering, sweating, high blood pressure and shaking when you stop taking Unidol 100mg Injection 2 ml suddenly. Your doctor will reduce the dose gradually to avoid withdrawal symptoms.

Does Unidol 100mg Injection 2 ml cause dry mouth?

Unidol 100mg Injection 2 ml may cause dry mouth as a common side effect. It is not necessary for everyone taking Unidol 100mg Injection 2 ml to experience this side effect. Drink plenty of water, suck on sugar candy or chew sugar-free gum to prevent dry mouth. If the condition worsens or persists, please consult a doctor.

Does Unidol 100mg Injection 2 ml cause fits?

Unidol 100mg Injection 2 ml may cause fits, especially when taken in high doses or if you have a history of fits. Therefore, it is recommended to inform your doctor if you ever had fits as it may increase the chance of getting fits.

Can I take Unidol 100mg Injection 2 ml with antidepressants?

You are not recommended to take Unidol 100mg Injection 2 ml with antidepressants (medicines used to treat depression) and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Unidol 100mg Injection 2 ml may increase the risk of fits. However, please consult a doctor before taking Unidol 100mg Injection 2 ml with other medicines.

Is Unidol 100mg Injection 2 ml addictive?

Yes, Unidol 100mg Injection 2 ml may cause addiction especially if taken for a prolonged time. Therefore, Unidol 100mg Injection 2 ml should be given only for a short duration under strict medical supervision, particularly to patients who are susceptible to drug abuse. Take Unidol 100mg Injection 2 ml only as advised by a doctor as overuse or misuse of Unidol 100mg Injection 2 ml can lead to overdose or death.

Drug-Drug Interactions Checker List

CARBAMAZEPINE
ONDANSETRON
FLUOXETINE
DOXEPIN
DROPERIDOL
MORPHINE
CODEINE
WARFARIN

Special Advise

Patients with severe liver or kidney insufficiency should avoid taking Unidol 100mg Injection 2 ml.

Disease/Condition Glossary

Pain: It is an unpleasant sensation caused by an injury or illness. Pain may be acute (short term) or chronic (long term). It can be general (overall body pains) or localized (pain in a specific area of the body). Pain is highly subjective as some people have a high tolerance for pain while others have a low tolerance. Pain may be caused due to cramps, headache, bone fractures, stomach pain, arthritis (swelling of one or more joints), muscle strain, cuts, flu, irritable bowel syndrome (intestinal disorder causing stomach pain, diarrhoea or constipation), fibromyalgia (muscle pain with stiffness and tenderness), certain disease conditions, or medical procedures.