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Reviewed By Sunny S , MBBS
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Synonym :

QUININE SULPHATE

Composition :

QUININE-600MG

Manufacturer/Marketer :

Unicure India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Uniquin EC 600mg Tablet

Uniquin EC 600mg Tablet belongs to the class of 'anti-malarial drugs', primarily used to treat and prevent malaria. Malaria is a disease caused by a plasmodium parasite transmitted by the bite of infected Anopheles mosquitoes. When an infected mosquito bites a healthy person, it transmits the 'Plasmodium parasite' into the bloodstream, which affects the red blood cells and liver cells. Malaria symptoms usually start ten days to four weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma and bloody stools.

Uniquin EC 600mg Tablet contains Quinine which treats malaria. It treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

Uniquin EC 600mg Tablet should be taken as prescribed by the doctor. Your doctor will decide the dose and duration based on your medical condition. Common side effects of Uniquin EC 600mg Tablet include headache, dizziness, loss of appetite, weakness, fever, chills, tiredness, muscle/joint pain, nausea, vomiting, abdominal pain, cough and trouble sleeping. These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor.

Before using Uniquin EC 600mg Tablet, inform your doctor if you recently used any prescription and non-prescription medications, including other anti-malarial or antibiotic drugs. Let your doctor know if you are allergic to Uniquin EC 600mg Tablet or its components. Inform your doctor if you have any liver or kidney problems or severe heart diseases. Let your doctor know if you are pregnant, planning to conceive, or a breastfeeding mother. Avoiding alcohol is recommended to rule out any possibility of side effects.

Uses of Uniquin EC 600mg Tablet

Malaria

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Oral Suspension/syrup: Shake the bottle well before each use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Medicinal Benefits

Uniquin EC 600mg Tablet belongs to the class of 'anti-malarial drugs,' containing Quinine, primarily used to treat and prevent malaria. It is also used to treat and prevent nighttime cramps in the legs. It treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Uniquin EC 600mg Tablet

  • Vomiting
  • Abdominal pain
  • Fever
  • Flushing of the skin
  • Headache
  • Dizziness
  • Deafness
  • Tiredness
  • Loss of appetite
  • Problems with vision or hearing.
  • Increased sweating
  • Nausea
  • Diarrhoea

Drug Warnings

Let your doctor know if you use any antibiotic drugs or have recently undergone treatment with other anti-malarial drugs. Inform your doctor if you have any allergic reactions to Uniquin EC 600mg Tablet or its components. Brief your medical history to the doctor if you have any liver or kidney problems, malarial infection of the brain, lungs or kidneys, severe heart diseases, electrolyte imbalance, hypokalemia (low potassium levels) or hypomagnesemia (low magnesium levels) before taking Uniquin EC 600mg Tablet. This medicine may affect QT prolongation which can cause serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram) and a family history of heart diseases. It is not recommended during the first three months of pregnancy. Do not use this medicine during breastfeeding. Once you have completed the course, you should wait at least one week before starting to breastfeed again. However, it is essential to let your doctor know if you are pregnant, planning to conceive or a breastfeeding mother. Avoiding alcohol is recommended to rule out any possibility of side effects like dizziness or drowsiness.

Drug-Drug Interactions

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QuinineZiprasidone
Critical
QuinineLoperamide
Severe

Drug-Drug Interactions

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QuinineZiprasidone
Critical
How does the drug interact with Uniquin EC 600mg Tablet:
Co-administration of Uniquin EC 600mg Tablet with Ziprasidone can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Uniquin EC 600mg Tablet with Ziprasidone together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
QuinineLoperamide
Severe
How does the drug interact with Uniquin EC 600mg Tablet:
When taken in combination Uniquin EC 600mg Tablet may significantly raise the loperamide levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking loperamide with Uniquin EC 600mg Tablet together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
QuinineMoxifloxacin
Severe
How does the drug interact with Uniquin EC 600mg Tablet:
Using moxifloxacin together with Uniquin EC 600mg Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Uniquin EC 600mg Tablet together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you experience any symptoms like an irregular heartbeat, heart problems, or feeling dizzy or short of breath, call your doctor right away. Do not discontinue any medications without first consulting your doctor.
QuinineAlfuzosin
Severe
How does the drug interact with Uniquin EC 600mg Tablet:
Taking Alfuzosin and Uniquin EC 600mg Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Alfuzosin and Uniquin EC 600mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
QuinineLidocaine
Severe
How does the drug interact with Uniquin EC 600mg Tablet:
Taking Lidocaine with Uniquin EC 600mg Tablet may cause methemoglobinemia (blood disorder in which too little oxygen is delivered to your cells).

How to manage the interaction:
Although taking Lidocaine and Uniquin EC 600mg Tablet together can evidently cause an interaction, it can be taken if your doctor has suggested it. However, consult the doctor immediately if you develop gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion. Do not stop using any medications without consulting doctor.
QuininePazopanib
Severe
How does the drug interact with Uniquin EC 600mg Tablet:
Taking Pazopanib with Uniquin EC 600mg Tablet may significantly reduces the blood levels of pazopanib.

How to manage the interaction:
Although there is a interaction between Pazopanib and Uniquin EC 600mg Tablet, but it can be taken if your doctor has advised it. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, fast or pounding heartbeats, chest pain or tightness, pain in your arms, back, neck, or jaw, shortness of breath, numbness or weakness on one side of your body, and difficulty speaking. Do not stop using any medications without a doctor's advice.
QuinineCeritinib
Severe
How does the drug interact with Uniquin EC 600mg Tablet:
Taking Ceritinib with Uniquin EC 600mg Tablet may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although taking Ceritinib and Uniquin EC 600mg Tablet together can evidently cause an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
QuinineEfavirenz
Severe
How does the drug interact with Uniquin EC 600mg Tablet:
Taking Efavirenz and Uniquin EC 600mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Efavirenz and Uniquin EC 600mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
QuinineGatifloxacin
Severe
How does the drug interact with Uniquin EC 600mg Tablet:
Taking Gatifloxacin with Uniquin EC 600mg Tablet can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Gatifloxacin with Uniquin EC 600mg Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
QuinineBupivacaine
Severe
How does the drug interact with Uniquin EC 600mg Tablet:
Taking Bupivacaine and Uniquin EC 600mg Tablet may cause methemoglobinemia, (a condition in which the iron in the hemoglobin molecule -the red blood pigment is defective, making it unable to carry oxygen effectively to the tissues).

How to manage the interaction:
Although taking bupivacaine and Uniquin EC 600mg Tablet together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience symptoms such as gray discoloration of the skin, abnormal blood coloration, nausea, headache, dizziness, lightheadedness, fatigue, shortness of breath, rapid or shallow breathing, a rapid heartbeat, palpitation, anxiety, or confusion, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Take nutritious food, including fresh fruits and vegetables, to help recover from malarial fever.
  • During malarial fever, the patient may experience appetite loss. In such cases, drink glucose water, fresh fruit juices and coconut water.
  • Include high-fibre foods like green leafy vegetables and fruits to aid digestion.
  • Take proper rest to help your body relax and heal faster.
  • Avoid or limit the intake of alcohol and caffeine.

Habit Forming

No

Therapeutic Class

ANTI- MALARIALS

Uniquin EC 600mg Tablet Substitute

Substitutes safety advice
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  • Rezquin 600mg Tablet

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    8.69per tablet
  • Quinocent 600mg Tablet

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Uniquin EC 600mg Tablet belongs to the class of 'anti-malarial drugs', containing Quinine, that treats malaria by increasing the levels of hemozoin (a toxic substance to the malarial parasite) in the blood. As a result, it kills the parasite and helps to stop the infection from spreading further.

If you have or have previously had Long QT syndrome, glucose-6-phosphate dehydrogenase deficiency (G-6-PD), myasthenia gravis (a muscular problem), optic neuritis (inflammation of the nerves in your eyes), or if taking Uniquin EC 600mg Tablet in the past caused bleeding, you should not take it.

Uniquin EC 600mg Tablet can cause a lowering of blood sugar levels. So, if you are diabetic, please inform your doctor before starting Uniquin EC 600mg Tablet, and dose adjustment might be required depending upon your medical condition.

No, finish the prescribed course even if you start to feel better. Stopping it early may make the infection come back and harder to treat.

Uniquin EC 600mg Tablet may affect the heart rhythm and cause QT prolongation (heart muscle takes longer than usual to recharge between beats). This QT prolongation can cause a serious fast/irregular heartbeat. Hence it is advised to inform your doctor if you have any heart-related problems like heart failure, slow heartbeat, QT prolongation in EKG or ECG (electrocardiogram) and a family history of heart diseases.

It is advised to have regular eye checkups while using Uniquin EC 600mg Tablet. Consult your doctor if you face any change in vision.

Drug-Drug Interactions Checker List

  • AMINOPHYLLINE
  • THEOPHYLLINE
  • AZITHROMYCIN
  • CLARITHROMYCIN
  • LEVOFLOXACIN
  • TETRACYCLINE
  • CITALOPRAM
  • AMITRIPTYLINE
  • CLOMIPRAMINE
  • DESIPRAMINE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • VORICONAZOLE
  • ATORVASTATIN
  • SIMVASTATIN
  • LOVASTATIN
  • DEXTROMETHORPHAN
  • ATAZANAVIR
  • INDINAVIR
  • RITONAVIR
  • SAQUINAVIR
  • CARBAMAZEPINE
  • OXCARBAZEPINE
  • PHENYTOIN
  • PRIMIDONE
  • CIMETIDINE
  • RANITIDINE
  • RIFAMPICIN
  • RIFABUTIN
  • HALOPERIDOL
  • THIORIDAZINE
  • AMANTADINE

Special Advise

  • Inform your doctor that you are taking Uniquin EC 600mg Tablet if you are undergoing medical tests.
  • Regular monitoring of heart function with ECG or EKG is necessary.
  • Liver and kidney function tests are recommended to rule out any chances of kidney or liver impairment.
  • Uniquin EC 600mg Tablet may decrease the effectiveness of hormonal birth control such as pills, patches or rings. This could cause pregnancy.
  • Regularly undergo eye tests while taking Uniquin EC 600mg Tablet.

Disease/Condition Glossary

Malaria: Malaria is a life-threatening disease caused by parasites entering the body through mosquito bites. This is a common disease in countries like Africa, South America and Southern Asia. This disease usually occurs when an Anopheles mosquito (infected with the parasite 'Plasmodium') bites a healthy individual and transfers the parasite into the bloodstream. Parasites that cause malaria include Plasmodium vivax, P. ovale, P. malaria and P. falciparum. Malaria symptoms usually start ten days to four weeks after the infection. They include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma and bloody stools.

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