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Composition :

IMATINIB-400MG

Manufacturer/Marketer :

United Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About UNITINIB 400MG CAPSULE

UNITINIB 400MG CAPSULE belongs to a class of drugs known as 'anti-cancer medication', primarily used to treat various types of cancer. It is used to treat cancer of the blood (chronic myeloid leukaemia and acute lymphocytic leukaemia) and gastrointestinal stromal tumour. Cancer is a genetic change in which the cells divide uncontrollably and spread into surrounding tissues. There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer, etc.

UNITINIB 400MG CAPSULE contains Imatinib, which is primarily used to treat cancer. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

You are advised to take UNITINIB 400MG CAPSULE for as long as your doctor has prescribed it for you, depending upon your medical condition. In some cases, you may experience nausea, vomiting, oedema, fatigue, muscle cramps, musculoskeletal pain, diarrhoea, rash, and abdominal pain. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently. 

Do not take UNITINIB 400MG CAPSULE if you are allergic to any of its ingredients. While taking UNITINIB 400MG CAPSULE, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF). Regular blood tests are required to monitor liver function and blood cells in the blood while taking UNITINIB 400MG CAPSULE. UNITINIB 400MG CAPSULE can cause swelling and water retention, so if you have unexpected rapid weight gain, please consult your doctor. If you ever had a hepatitis B infection, please tell your doctor before starting UNITINIB 400MG CAPSULE as it can make hepatitis B active again. 

Uses of UNITINIB 400MG CAPSULE

Cancer

Directions for Use

Swallow the medicine as a whole with a glass of water. Do not crush, chew or break it.

Medicinal Benefits

UNITINIB 400MG CAPSULE belongs to a class of drugs known as 'anti-cancer medication' containing Imatinib, primarily used to treat various cancer types. It is used to treat cancer of the blood (chronic myeloid leukaemia and acute lymphocytic leukaemia) and gastrointestinal stromal tumour. It works by inhibiting an enzyme responsible for cancer cell proliferation and induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take UNITINIB 400MG CAPSULE if you are allergic to any of its ingredients. UNITINIB 400MG CAPSULE may cause blurry vision and dizziness, so do not drive or operate any machinery which requires concentration. While taking UNITINIB 400MG CAPSULE, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF) while going out, as it can lead to a skin rash if you are not using a strong SPF. UNITINIB 400MG CAPSULE can cause leg swelling and water retention (oedema), so if you have unexpected rapid weight gain, please consult your doctor. If you ever had a hepatitis B infection, please tell your doctor before starting UNITINIB 400MG CAPSULE as it can make hepatitis B active again. UNITINIB 400MG CAPSULE may make you more susceptible to infections; consult your doctor if you develop any signs of infections, fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Drug-Drug Interactions

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ImatinibConivaptan
Critical

Drug-Drug Interactions

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How does the drug interact with Unitinib 400mg Capsule:
When Regorafenib is taken with Unitinib 400mg Capsule, it may increase the level of Unitinib 400mg Capsule which may lead to side effects.

How to manage the interaction:
Taking Regorafenib with Unitinib 400mg Capsule is not recommended, it can be taken if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor.
ImatinibConivaptan
Critical
How does the drug interact with Unitinib 400mg Capsule:
When Unitinib 400mg Capsule is taken with Conivaptan, it can cause increase in the blood levels of conivaptan leading to side effects.

How to manage the interaction:
Taking Unitinib 400mg Capsule with Conivaptan is not recommended, it can be taken if recommended by your doctor. However, if you experience any unusual symptoms, consult the doctor.
ImatinibCobimetinib
Critical
How does the drug interact with Unitinib 400mg Capsule:
When Cobimetinib is taken with Unitinib 400mg Capsule, it can increase the risk of serious side effects.

How to manage the interaction:
Taking Unitinib 400mg Capsule with Cobimetinib is not recommended, but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor.
ImatinibEliglustat
Critical
How does the drug interact with Unitinib 400mg Capsule:
When Unitinib 400mg Capsule is taken with Eliglustat, Unitinib 400mg Capsule increases levels of eliglustat which may lead to side effects.

How to manage the interaction:
Taking Unitinib 400mg Capsule with Eliglustat is not recommended, it can be taken if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor.
ImatinibFlibanserin
Critical
How does the drug interact with Unitinib 400mg Capsule:
Taking Unitinib 400mg Capsule with Flibanserin may increase the level of flibanserin in body leading to side effects.

How to manage the interaction:
Taking Unitinib 400mg Capsule with Flibanserin is not recommended, but it can be taken if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor.
How does the drug interact with Unitinib 400mg Capsule:
Coadministration of Ivabradine with Unitinib 400mg Capsule can increase the levels of Ivabradine in the body. This increases the risk or severity of side effects.

How to manage the interaction:
Taking Ivabradine with Bosutinib together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Unitinib 400mg Capsule:
When Unitinib 400mg Capsule is taken with Cisapride, it can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Taking Unitinib 400mg Capsule with Cisapride is not recommended, it can be taken if a doctor has prescribed this. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue the medication without consulting a doctor.
ImatinibDihydroergotamine
Critical
How does the drug interact with Unitinib 400mg Capsule:
When Dihydroergotamine is taken with Unitinib 400mg Capsule, it increases levels of dihydroergotamine leading to side effects.

How to manage the interaction:
Taking Unitinib 400mg Capsule with Dihydroergotamine is not recommended, it can be taken if advised by your doctor. However, if you experience any unusual symptoms, consult the doctor.
ImatinibVenetoclax
Critical
How does the drug interact with Unitinib 400mg Capsule:
When Venetoclax is taken with Unitinib 400mg Capsule, Unitinib 400mg Capsule may increase the level of venetoclax which may lead to side effects.

How to manage the interaction:
Taking Unitinib 400mg Capsule with Venetoclax is not recommended, it can be taken if prescribed by your doctor. However, if you experience any unusual symptoms, consult the doctor.
How does the drug interact with Unitinib 400mg Capsule:
Using Lurasidone together with Unitinib 400mg Capsule may result in significantly higher Lurasidone blood levels. This may increase the possibility of negative effects like Parkinson's disease. (It is a brain disorder that produces uncontrollable movements.)

How to manage the interaction:
Taking Lurasidone with Unitinib 400mg Capsule is not recommended as it leads to an interaction, it can be used if prescribed by a doctor. Consult a doctor if you have any abnormal muscle activity, fits, high blood sugar, high sugars, high cholesterol, heat intolerance or heat stroke, dizziness, lightheadedness, headache, flushing, fainting, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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IMATINIB-400MGHerbal products/medicines

Drug-Food Interactions

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IMATINIB-400MGHerbal products/medicines
Common Foods to Avoid:
St. John’S Wort

How to manage the interaction:
St. John's Wort may reduce the effectiveness of Unitinib 400mg Capsule. Avoid St. John's Wort during treatment with Unitinib 400mg Capsule.

Diet & Lifestyle Advise

  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate and high fibre content. Also, eat small and frequent meals for a speedy recovery.
  • Avoid smoking and alcohol consumption. Also, avoid high fat and cholesterol diet.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

UNITINIB 400MG CAPSULE contains Imatinib, an anti-cancer medication that works by inhibiting an enzyme responsible for the proliferation of cancer cells and hence induces cell death (apoptosis). As a result, the growth and spread of cancer cells are stopped or slowed down.

Regular monitoring of blood and urine tests and weight checks are required. An effective way of contraception should be used by both men and women while taking UNITINIB 400MG CAPSULE.

Yes, you might become more sensitive to sunlight while taking UNITINIB 400MG CAPSULE, so it is important to protect your skin with a high sun protection factor (SPF) while going out, as it can lead to a skin rash if you are not using a strong SPF.

In elderly patients taking UNITINIB 400MG CAPSULE, the risk of side effects is more. For the elderly, dose adjustment might be required, or your doctor might prescribe any other medication safe for the elderly.

If you are having surgery, including dental surgery, please inform your doctor if you are taking UNITINIB 400MG CAPSULE as your doctor might stop UNITINIB 400MG CAPSULE before undergoing surgery.

UNITINIB 400MG CAPSULE can make you more likely to get infections or may worsen any current infections. Avoid contact with people with infections that may spread to others (such as chickenpox, measles, or flu). Consult your doctor if you have been exposed to an infection or for more details.

Drug-Drug Interactions Checker List

  • WARFARIN
  • ASPIRIN
  • AMLODIPINE
  • METOPROLOL
  • NIFEDIPINE
  • QUINIDINE
  • ATORVASTATIN
  • LOVASTATIN
  • SIMVASTATIN
  • CYCLOSPORINE
  • ERYTHROMYCIN
  • TELITHROMYCIN
  • ITRACONAZOLE
  • VORICONAZOLE
  • KETOCONAZOLE
  • TRIAZOLAM
  • ALPRAZOLAM
  • ESTAZOLAM
  • PRIMIDONE
  • PHENOBARBITAL
  • PHENYTOIN
  • SAQUINAVIR
  • RITONAVIR
  • SILDENAFIL

Special Advise

  • A regular blood test is required to monitor liver function and blood cells in blood while taking UNITINIB 400MG CAPSULE.
  • Always take it with food and a full glass of water to prevent nausea.
  • UNITINIB 400MG CAPSULE can cause swelling and water retention, so if you have unexpected rapid weight gain, please consult your doctor. 
  • While taking UNITINIB 400MG CAPSULE, you might become more sensitive to sunlight, so it is important to protect your skin with a high sun protection factor (SPF) while going out, as it can lead to a skin rash if you are not using a strong SPF.
  • Do not have immunisations with live vaccines (for mumps, rubella, measles and BCG, yellow fever and shingles or pox chicken) while you’re having treatment and for up to 12 months afterwards. 
  • Contact your doctor immediately if you experience any infection signs, including a temperature above 37.5 C or below 36 C.

Disease/Condition Glossary

Cancer: It is a genetic change in which our cells divide uncontrollably and spread into surrounding tissues. There are two types of cancer: benign (localized) and metastatic (spread to the whole body). There are more than 100 types of cancer, including blood cancer, lung cancer, breast cancer, etc. Cancer growth can be prevented by chemotherapy (by strong antibiotics), radiation and stem cell therapy. To date, there is no cure for cancer.

Chronic myeloid leukaemia: It is a type of cancer that affects the white blood cells and tends to progress slowly over many years. It can occur at any age but is most common in adults around 60-65.

Acute lymphocytic leukaemia: A type of leukaemia (blood cancer) that comes on quickly and is fast-growing. In acute lymphoblastic leukaemia, there are too many lymphoblasts (immature white blood cells) in the blood and bone marrow.

A gastrointestinal stromal tumour (GIST): It is a type of tumour in the stomach or small intestine. The tumours develop into the specialized cells called interstitial cells of Cajal (ICCs).

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