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Written By Urvashi Bharti , MBBS
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
Non returnable*
COD available

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Composition :

FEBUXOSTAT-40MG

Manufacturer/Marketer :

Corvin Pharmaceuticals

Consume Type :

ORAL

Return Policy :

Not Returnable

About Uratex 40mg Tablet

Uratex 40mg Tablet belongs to a class of anti-gout medications, also known as xanthine oxidase inhibitors, widely used to prevent severe gout attacks or flares. Gout is a chronic condition that occurs due to the deposition of uric acid crystals in the joints. It is characterized by intense pain and swelling at the affected joints. Uratex 40mg Tablet prevents the sudden attacks of pain caused by severe gout and decreases pain, swelling, and inflammation.

Uratex 40mg Tablet contains febuxostat. It works by inhibiting the enzyme xanthine oxidase (an enzyme that helps your body make uric acid), thereby reducing the level of uric acid in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. Uratex 40mg Tablet is used to prevent gout attacks or flares.

Your doctor will advise you on how often you take off the Uratex 40mg Tablet based on your medical condition. The common side effects of Uratex 40mg Tablet nausea, rash, dizziness, diarrhoea, pain, rash, inaccurate liver function test results, gout flare-ups (intense joint pain that comes on suddenly, often in the middle of the night), localized swelling due to retention of fluids in tissues (oedema). Most of these side effects of Uratex 40mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not stop taking a Uratex 40mg Tablet of your own. Stopping it may worsen your condition and increase the risk of increased uric acid levels and future gout attacks. Inform your doctor if you have allergic to Uratex 40mg Tablet or any other medicines, have a heart problem (Uratex 40mg Tablet may cause heart problems that can lead to heart attack), or have kidney/liver disease. Some people experience more gout flare-ups when you start taking Uratex 40mg Tablet. You should continue taking this drug even if gout flare-ups occur. Your doctor may give you combination therapy to prevent flare-ups when you start Uratex 40mg Tablet. The safety and effectiveness of children under 18 years of age have not been established, so Uratex 40mg Tablet should not be given to them. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Uratex 40mg Tablet.

Uses of Uratex 40mg Tablet

Treatment of severe gout, prevention of gout attacks

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Uratex 40mg Tablet is a class of medications called xanthine oxidase (enzyme that helps your body to make the uric acid) inhibitors. It works by inhibiting the enzyme xanthine oxidase, thereby reducing the level of uric acid that is made in your body. Thus, it reduces the inflammation caused by uric acid crystals in affected joints, thereby reducing pain, swelling and inflammation. Uratex 40mg Tablet is used to prevent gout attacks or flares.

Storage

Store in a cool and dry place away from sunlight
Side effects of Uratex 40mg Tablet
  • Drink plenty of water to eliminate uric acid.
  • Avoid purine-rich foods such as red meat, organ meats, certain seafood (sardines, anchovies) and too much alcohol.
  • Regularly do low impact exercises like swimming or walking.
  • To reduce pain and swelling, apply ice packs to the affected area.
  • Take rest and avoid activities that strain the affected joint.
  • Elevate the affected joint to encourage fluid drainage.
  • Aim for weight loss and maintain a healthy body weight to reduce the risk of gout.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

You should avoid taking Uratex 40mg Tablet if you are allergic to Uratex 40mg Tablet, or have heart-related problems, as it increases the risk of a heart attack. It should be used cautiously in patients with kidney problems and blood disorders. Caution is required before taking Uratex 40mg Tablet if you are pregnant, planning to become pregnant, or already a breastfeeding mother. The safety and effectiveness of children under 18 years of age have not been established, so Uratex 40mg Tablet should not be given to them.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Uratex 40mg Tablet:
Coadministration of Mercaptopurine with Uratex 40mg Tablet can increase the blood levels of mercaptopurine.

How to manage the interaction:
Taking Mercaptopurine with Uratex 40mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to your doctor.
How does the drug interact with Uratex 40mg Tablet:
Taking azathioprine and Uratex 40mg Tablet together can increase the blood levels of azathioprine

How to manage the interaction:
Taking Azathioprine with Uratex 40mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
FebuxostatLomitapide
Severe
How does the drug interact with Uratex 40mg Tablet:
Coadministration of Uratex 40mg Tablet with lomitapide can increase the risk of liver problems.

How to manage the interaction:
Although taking Uratex 40mg Tablet with Lomitapide can result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
How does the drug interact with Uratex 40mg Tablet:
Coadministration of Teriflunomide with Uratex 40mg Tablet can increase the risk of liver problems.

How to manage the interaction:
Although taking Uratex 40mg Tablet and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
How does the drug interact with Uratex 40mg Tablet:
Coadministration of Uratex 40mg Tablet with leflunomide can increase the risk of liver problems.

How to manage the interaction:
Although taking Uratex 40mg Tablet with Leflunomide can result in an interaction, they can be taken together if prescribed by your doctor. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.
How does the drug interact with Uratex 40mg Tablet:
Coadministration of Uratex 40mg Tablet with ketoconazole can increase the risk of liver problems.

How to manage the interaction:
Although taking Uratex 40mg Tablet with Ketoconazole can result in an interaction, they can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting a doctor.
FebuxostatMipomersen
Severe
How does the drug interact with Uratex 40mg Tablet:
Coadministration of Uratex 40mg Tablet with Mipomersen can increase the risk of liver problems.

How to manage the interaction:
Co-administration of Uratex 40mg Tablet with Mipomersen can result in an interaction, but it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience fever, joint pain or swelling, skin rash, vomiting, abdominal pain, dark urine, or yellowing of the skin or eyes. Do not discontinue using any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include more glucosamine, chondroitin sulfate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish can help in reducing inflammation in the tissue.
  • Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do low-impact aerobic movements like walking on a treadmill and swimming. You can also strengthen your muscles by lifting light weights.
  • Your sitting posture is important, especially when you have pain and inflammation. Try to sit as little as possible and only for a short duration of time. Long-term immobility is harmful in conditions like arthritis. Use back support like a rolled-up towel to minimise pain at the back of your spine curve. Keep your knees and hips at a right angle. Besides this, you can also use a footrest if required.
  • Avoid a high purine-rich diet, including organ meats (kidneys, liver, and sweetbreads) and oily fish (sardines, anchovies, and herring).
  • Limit meat in favour of plant-based proteins like beans and legumes.
  • Eat complex carbohydrates, such as whole-grain bread, fruits, and vegetables, rather than sugary sweets and refined carbohydrates like white bread.
  • Avoid drinking beer and alcoholic beverages and drink plenty of water or other nonalcoholic beverages.

Habit Forming

No

Therapeutic Class

ANTI- GOUT MEDICATIONS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Drug-Drug Interactions Checker List

  • MERCAPTOPURINE
  • METHOTREXATE
  • AZATHIOPRINE
  • THEOPHYLLINE
  • ROSIGLITAZONE

Special Advise

  • Please consult your doctor and check your levels of uric acid two weeks after starting Uratex 40mg Tablet. Your goal is a uric acid level in your blood that is less than 6 mg/dL.

Disease/Condition Glossary

Gout: Gout is a type of arthritis called 'gouty arthritis'. It is caused by a build-up of a naturally occurring chemical (uric acid) in your body (hyperuricemia). The excess uric acid deposit and crystallize in the joints leading to pain and inflammation. The general signs and symptoms of gout include sudden, severe attacks of pain, swelling, redness, and tenderness in the joints, mostly in the joint at the base of the big toe. Patients with gout may often experience acute attacks that result in sudden and severe pain, often waking you up in the middle of the night with the sensation that your big toe is on fire.

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