VALPO CR 300MG TABLET belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, VALPO CR 300MG TABLET is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. 
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VALPO CR 300MG TABLET contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. VALPO CR 300MG TABLET increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 
 
You can take VALPO CR 300MG TABLET with or without food. You are advised to take VALPO CR 300MG TABLET for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking VALPO CR 300MG TABLET without consulting your doctor to avoid worsening of seizures. Contact your doctor if your child gets her first-period whilst on treatment with VALPO CR 300MG TABLET. Do not take VALPO CR 300MG TABLET if you are pregnant as it could cause serious congenital disabilities. If you are of child-bearing age, use effective contraception while taking VALPO CR 300MG TABLET. Consult your doctor before taking VALPO CR 300MG TABLET if you are breastfeeding. Do not drive or operate machinery as VALPO CR 300MG TABLET may cause drowsiness and dizziness. Avoid consuming alcohol along with VALPO CR 300MG TABLET as it could lead to increased dizziness and sleepiness.

VALPO CR 300MG TABLET belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Additionally, VALPO CR 300MG TABLET is also used to treat bipolar disorder and prevent migraine headaches. VALPO CR 300MG TABLET decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. VALPO CR 300MG TABLET is used to treat both localized (seizures which affect only a part of the brain) and generalized seizures (seizures which affect the entire brain).

• Stomach pain
• Nausea
• Vomiting
• Dry mouth
• Tremors
• Tiredness
• Sleepiness
• Headache
• Weight gain
• Hair loss

Do not take VALPO CR 300MG TABLET if you are allergic to any of its contents; if you have liver problems, porphyria, urine-related problems (like urea cycle disorder), diabetes, immune system disorder or kidney problems. Consult your doctor immediately if you experience suicidal tendencies while taking VALPO CR 300MG TABLET. Contact your doctor if your child gets her first period during the treatment with VALPO CR 300MG TABLET. Do not take VALPO CR 300MG TABLET if you are pregnant unless prescribed by the doctor as it is pregnancy category C medicine and can cause serious congenital disabilities. Consult your doctor before taking VALPO CR 300MG TABLET if you are breastfeeding. VALPO CR 300MG TABLET may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with VALPO CR 300MG TABLET as it could lead to increased dizziness and sleepiness. 

Drug-Drug Interactions: VALPO CR 300MG TABLET may have interaction with pain killers (aspirin), anti-epileptics (phenobarbital, primidone, phenytoin, carbamazepine, topiramate, acetazolamide, lamotrigine, felbamate), blood thinner (warfarin), anti-HIV (zidovudine, lopinavir, ritonavir), anti-depressant (moclobemide, selegiline, linezolid, amitriptyline, sertraline), anti-psychotic (quetiapine, olanzapine, risperidone), calcium channel blocker (nimodipine), anaesthetic (propofol), hormone (oestrogen, levonorgestrel), anti-malarial (mefloquine, chloroquine), antacid (cimetidine), antibiotics (imipenem, meropenem, rifampicin, erythromycin), bile-acid sequestrant (cholestyramine), benzodiazepine (clonazepam, diazepam).

Drug-Food Interactions: Avoid alcohol consumption while taking VALPO CR 300MG TABLET as it might cause increased dizziness and sleepiness. 

Drug-Disease Interactions: Inform your doctor if you have depression, liver disease, urea cycle disorders, suicidal tendency, HIV disease, or thrombocytopenia (low levels of platelets).

• ASPIRIN
• PHENOBARBITAL
• PHENYTOIN
• PRIMIDONE
• CARBAMAZEPINE
• TOPIRAMATE
• ACETAZOLAMIDE
• LAMOTRIGINE
• FELBAMATE
• WARFARIN
• ZIDOVUDINE
• LOPINAVIR
• RITONAVIR
• MOCLOBEMIDE
• SELEGILINE
• LINEZOLID
• AMITRIPTYLINE
• SERTRALINE
• QUETIAPINE
• OLANZAPINE
• RISPERIDONE
• NIMODIPINE
• PROPOFOL
• ESTROGEN
• LEVONORGESTREL
• MEFLOQUINE
• CHLOROQUINE
• CIMETIDINE
• IMIPENEM
• MEROPENEM
• RIFAMPICIN
• ERYTHROMYCIN
• CLONAZEPAM
• DIAZEPAM
• CHOLESTYRAMINE

• A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
• Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
• Exercising regularly helps in maintaining weight and improving overall health. 
• Rest well; get plenty of sleep.
• Avoid smoking and alcohol consumption.
• Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
• Have a seizure response plan that helps those around you know what to do.
• Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
• Understand what triggers seizures and try reducing or avoiding them.
• Please pay attention to overall health as it can help in reducing seizure activity.
• Install an alarm or emergency device to get assistance during a seizure attack.

• Contact your doctor if your child gets her first-period whilst on treatment with VALPO CR 300MG TABLET.
• VALPO CR 300MG TABLET might affect blood and urine tests. Inform the person doing the tests that you are taking VALPO CR 300MG TABLET.
• If you are of child-bearing age, use effective contraception without interruptions during your entire treatment with VALPO CR 300MG TABLET.
• Consult your doctor immediately if you become pregnant while taking VALPO CR 300MG TABLET.

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury or stroke.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows.