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  3. Valrate Syrup 100 ml

Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
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Manufacturer/Marketer :

3C Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Return Policy :

Not Returnable

NPPA :

Regulated

About Valrate Syrup

Valrate Syrup belongs to the group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Valrate Syrup is also used to treat bipolar disorder and prevent symptoms of migraine (like a headache). Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. 
­ 
Valrate Syrup contains 'Sodium valproate', which decreases the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Valrate Syrup increases the amount of a chemical substance called GABA; this helps block the nerve transmission across the brain and provides a calming effect. Thereby helps treat bipolar disorder. 
 
You can take Valrate Syrup with or without food. You are advised to take Valrate Syrup for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as stomach pain, nausea, vomiting, dry mouth, tremors, tiredness, sleepiness, headache, weight gain, and hair loss. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Please do not stop taking Valrate Syrup without consulting your doctor to avoid worsening of seizures. Contact your doctor if your child gets her first-period whilst on treatment with Valrate Syrup . Do not take Valrate Syrup if you are pregnant as it could cause serious congenital disabilities. If you are of child-bearing age, use effective contraception while taking Valrate Syrup . Consult your doctor before taking Valrate Syrup if you are breastfeeding. Do not drive or operate machinery as Valrate Syrup may cause drowsiness and dizziness. Avoid consuming alcohol along with Valrate Syrup as it could lead to increased dizziness and sleepiness.

Uses of Valrate Syrup

Epilepsy, Bipolar disorder, Migraine

Directions for Use

Tablet/Capsule: Swallow it as a whole with water; do not chew, or break the tablet/capsule. Syrup/Suspension/Drops: Take the prescribed dose/quantity by mouth using the measuring cup/dosing syringe; shake the pack well before each use.

Key Benefits

Valrate Syrup belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy (fits). Additionally, Valrate Syrup is also used to treat bipolar disorder and prevent migraine headaches. Valrate Syrup decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Valrate Syrup is used to treat both localized (seizures which affect only a part of the brain) and generalized seizures (seizures which affect the entire brain).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Valrate Syrup if you are allergic to any of its contents; if you have liver problems, porphyria, urine-related problems (like urea cycle disorder), diabetes, immune system disorder or kidney problems. Consult your doctor immediately if you experience suicidal tendencies while taking Valrate Syrup . Contact your doctor if your child gets her first period during the treatment with Valrate Syrup . Do not take Valrate Syrup if you are pregnant unless prescribed by the doctor as it is pregnancy category C medicine and can cause serious congenital disabilities. Consult your doctor before taking Valrate Syrup if you are breastfeeding. Valrate Syrup may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Valrate Syrup as it could lead to increased dizziness and sleepiness. 

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Valrate Syrup 100 ml:
Combining Sodium phenylbutyrate and Valrate Syrup 100 ml can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Valrate Syrup 100 ml is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Teriflunomide and Valrate Syrup 100 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Valrate Syrup 100 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Lithium with Valrate Syrup 100 ml can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Valrate Syrup 100 ml can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Valrate Syrup 100 ml with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Valrate Syrup 100 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Leflunomide and Valrate Syrup 100 ml can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Valrate Syrup 100 ml can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Valrate Syrup 100 ml:
The combined use of Ertapenem and Valrate Syrup 100 ml can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Valrate Syrup 100 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Ketamine and Valrate Syrup 100 ml can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Valrate Syrup 100 ml can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Meropenam and Valrate Syrup 100 ml together can reduce the effect of Valrate Syrup 100 ml.

How to manage the interaction:
Co-administration of Meropenam and Valrate Syrup 100 ml can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Valrate Syrup 100 ml:
Co-administration of Vorinostat with Valrate Syrup 100 ml can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Valrate Syrup 100 ml can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Valrate Syrup 100 ml:
Using buprenorphine together with Valrate Syrup 100 ml may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Valrate Syrup 100 ml can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilizing fat instead of glucose for the generation of energy.
  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well; get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan that helps those around you know what to do.
  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health as it can help in reducing seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Side Effects of Valrate Syrup

  • Stomach pain
  • Nausea
  • Vomiting
  • Dry mouth
  • Tremors
  • Tiredness
  • Sleepiness
  • Headache
  • Weight gain
  • Hair loss

Habit Forming

No

Therapeutic Class

[ANTICONVULSANT]

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Valrate Syrup decreases the excessive and abnormal nerve activity in the brain. It balances the brain's chemical messenger and prevents overactivity of the brain, thereby controlling seizures episodes.

Valrate Syrup helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA; this helps in blocking the nerve transmission across the brain and provides a calming effect.

Valrate Syrup limits the transmission of nerve pain, thereby prevents migraine headache. Migraine is a neurological condition which is characterized by intense headaches.

Do not discontinue Valrate Syrup without consulting your doctor. To treat your condition effectually, continue taking Valrate Syrup for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Valrate Syrup ; your doctor will reduce the dose gradually to avoid worsening of seizures.

Birth-control pills like oestrogen-containing products may affect the way Valrate Syrup works. It is better to consult the doctor if you are using birth control pills to avoid pregnancy.

Valrate Syrup may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Valrate Syrup might cause fertility issues in both men and women. However, it can be reversible upon discontinuation of Valrate Syrup . In rare cases, Valrate Syrup can be a contributing factor in male infertility.

Limit caffeine intake, avoid smoking and mouthwashes containing alcohol, drink water regularly, and chew sugar-free gum/candy might prevent dry mouth.

Valrate Syrup may change the results of liver enzymes, and urine and blood tests. Inform the person doing the tests that you are taking Valrate Syrup .

Drug-Drug Interactions Checker List

  • ASPIRIN
  • PHENOBARBITAL
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • TOPIRAMATE
  • ACETAZOLAMIDE
  • LAMOTRIGINE
  • FELBAMATE
  • WARFARIN
  • ZIDOVUDINE
  • LOPINAVIR
  • RITONAVIR
  • MOCLOBEMIDE
  • SELEGILINE
  • LINEZOLID
  • AMITRIPTYLINE
  • SERTRALINE
  • QUETIAPINE
  • OLANZAPINE
  • RISPERIDONE
  • NIMODIPINE
  • PROPOFOL
  • ESTROGEN
  • LEVONORGESTREL
  • MEFLOQUINE
  • CHLOROQUINE
  • CIMETIDINE
  • IMIPENEM
  • MEROPENEM
  • RIFAMPICIN
  • ERYTHROMYCIN
  • CLONAZEPAM
  • DIAZEPAM
  • CHOLESTYRAMINE

Special Advise

  • Contact your doctor if your child gets her first-period whilst on treatment with Valrate Syrup .
  • Valrate Syrup might affect blood and urine tests. Inform the person doing the tests that you are taking Valrate Syrup .
  • If you are of child-bearing age, use effective contraception without interruptions during your entire treatment with Valrate Syrup .
  • Consult your doctor immediately if you become pregnant while taking Valrate Syrup .

Disease/Condition Glossary

Epilepsy: Epilepsy is a sudden rush of electricity in the brain. It is a disorder of the nervous system which occurs due to disturbed nerve cell activity in the brain. In epilepsy the brain's electrical rhythms become imbalanced, resulting in recurrent seizures. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements or sensations. Seizures are of two types: generalized and partial seizures. Generalized seizures affect the entire brain, whereas partial seizures affect only a part of the brain. Seizures can cause uncontrollable muscle twitches and spasms. Stronger seizures may cause people to become confused or unconscious. Possible causes include high fever, trauma, genetic disorder, brain injury or stroke.

Bipolar disorder: Bipolar disorder, also known as manic depression or bipolar disease, is a mental health disorder associated with episodes of mood swings ranging from manic highs to depressive lows. 

Have a query?

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Alcohol

Safe if prescribed

Avoid consumption of alcohol while taking Valrate Syrup as it may cause increased dizziness and sleepiness.

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Pregnancy

Consult your doctor

Valrate Syrup belongs to pregnancy category D. Avoid taking Valrate Syrup if you are pregnant as it could lead to serious birth defects.

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Breast Feeding

Consult your doctor

Valrate Syrup may pass into breastmilk. Consult your doctor before taking Valrate Syrup if you are breastfeeding.

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Driving

Safe if prescribed

Valrate Syrup causes dizziness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.

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Liver

Consult your doctor

Valrate Syrup should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

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Kidney

Consult your doctor

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Safe if prescribed

Valrate Syrup can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

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