VARILRIX VACCINE INJECTION 0.5ML belongs to the class of medications called ‘immunizing agents’ used to prevent varicella or chickenpox. Chickenpox is a vaccine-preventable viral infection caused by the varicella-zoster virus. It is highly contagious, especially in people who have never had the disease or have not been vaccinated against it. Symptoms include rash, small painful blisters, fever, sore throat, and body pain.

VARILRIX VACCINE INJECTION 0.5ML is an immunizing agent or vaccine made from a live, weakened or attenuated varicella-zoster virus. It helps to provide persistent or long-lasting protection against varicella or chickenpox. VARILRIX VACCINE INJECTION 0.5ML helps develop immunity by forming antibodies by stimulating the immune system. It is essential to take the vaccine doses per the doctor’s advice for effective protection against the disease.

VARILRIX VACCINE INJECTION 0.5ML will be administered by a healthcare professional; hence do not self-administer. VARILRIX VACCINE INJECTION 0.5ML may cause side effects such as fever, pain, swelling, and redness at the injection site. These side effects are mild and temporary. However, if these side effects persist or worsen, inform your doctor immediately.

It is not recommended to take VARILRIX VACCINE INJECTION 0.5ML if you are allergic to neomycin or any contents present in this medicine. VARILRIX VACCINE INJECTION 0.5ML should not be given to people with blood disorders or cancer of the blood (leukaemia) or immune system (lymphoma), with a weak immune system, such as patients with HIV or AIDS, who are receiving immunosuppressants or receiving high doses of corticosteroids, who have active untreated tuberculosis, and who have a temperature higher than  38.50c VARILRIX VACCINE INJECTION 0.5ML should not be given to pregnant women and used with caution in breastfeeding mothers. VARILRIX VACCINE INJECTION 0.5ML is not recommended for children below 9 months of age. VARILRIX VACCINE INJECTION 0.5ML should be used with caution in elderly people. VARILRIX VACCINE INJECTION 0.5ML may not interact with alcohol and may not affect your driving ability.

VARILRIX VACCINE INJECTION 0.5ML provides active immunization against varicella-zoster virus or chickenpox disease for healthy individuals above nine months of age. It benefits people who are non-immune and at risk of infection, such as healthcare workers or workers in children's day-care centres, non-immune parents of young children, and non-immune household contacts of patients with weak immune systems with no history of the disease.  Vaccination within three days of exposure to the virus can reduce the risk of infection and the severity of the disease.

• Fever
• Pain or redness at the injection site
• Swelling at the injection site

People who have been vaccinated with VARILRIX VACCINE INJECTION 0.5ML should avoid close contact for up to 6 weeks with the following individuals: who have not been previously vaccinated against chickenpox, children/adults/pregnant women who have never had chickenpox, who have a weak immune system or receiving immune suppressants, and new-born babies whose mother have never had chickenpox. Adults and children with weak immune systems who receive VARILRIX VACCINE INJECTION 0.5ML should be closely monitored as this vaccine is less effective in these people. In people who have undergone blood or plasma transfusion, who had taken human normal immunoglobulin or varicella-zoster immunoglobulin, VARILRIX VACCINE INJECTION 0.5ML vaccine should be avoided or postponed for at least five months in these people. Besides, people should not receive any immunoglobulin medicines for one month following VARILRIX VACCINE INJECTION 0.5ML. You should not take pain killer (aspirin) for six weeks following VARILRIX VACCINE INJECTION 0.5ML as it may cause Reye syndrome (a severe condition that causes liver and brain damage). Women of childbearing potential should use reliable contraceptive methods as it is not recommended to get pregnant for one month following VARILRIX VACCINE INJECTION 0.5ML vaccination.

Drug-Drug Interactions: VARILRIX VACCINE INJECTION 0.5ML should not be given to patients taking immune suppressive therapy (tacrolimus, cyclosporine, and azathioprine, etc.) or high doses of corticosteroids (prednisone, methylprednisolone, and dexamethasone, etc.). VARILRIX VACCINE INJECTION 0.5ML may interact with a pain killer (aspirin) and cause Reye syndrome (a severe condition that causes liver and brain damage). VARILRIX VACCINE INJECTION 0.5ML may also interact with immunoglobulin therapy (human normal immunoglobulin and varicella-zoster immune globulin).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: VARILRIX VACCINE INJECTION 0.5ML should not be used in patients with cancer-related to blood (leukaemia) and immune system (lymphoma), HIV or AIDS, active untreated tuberculosis, and fever (higher than 38.5°C).

• TACROLIMUS
• CYCLOSPORINE
• AZATHIOPRINE
• PREDNISONE
• METHYLPREDNISOLONE
• DEXAMETHASONE
• ASPIRIN
• HUMAN NORMAL IMMUNOGLOBULIN
• VARICELLA ZOSTER IMMUNE GLOBULIN

• Eat bland foods such as rice, pasta, and oatmeal and soft foods such as mashed potatoes, sweet potatoes, boiled eggs, avocado, and boiled chicken.
• Prefer eating yoghurt, milkshakes, and smoothies. Avoid eating spicy, salty, and acidic foods.
• Stay hydrated. Prefer drinks such as coconut water, herbal teas, low-sugar drinks, and electrolyte-infused drinks.
• Do not scratch or itch the rashes, as it may worsen them. Regular hand washing and trimming the nails can avoid the spreading of infection.
• Monitor your temperature regularly. Sponging can help to reduce fever.
• Take adequate rest and sleep.
• Stay isolated and do not go outside until the last blister has disappeared.
• Vaccinate all the contacts (family members or caretakers) within 3 to 5 days post-exposure to the virus.

• VARILRIX VACCINE INJECTION 0.5ML should not be given intravenously (IV). It is given under the skin or into the muscle. If given into the muscle, the upper arm area is preferred in adults, and the thigh area is preferred in children. The injection is usually given under the skin if you have a blood clotting disorder or thrombocytopenia (low levels of platelets).
• If there is a requirement to give more than one live virus vaccine simultaneously, these injections should be given at different sites. However, if it is not necessary to give them on the same day, they should be spaced at an interval of at least four weeks.

Chickenpox: The varicella-zoster virus causes a vaccine-preventable viral infection. It is extremely contagious, especially among people who have never had the disease or have not been immunised against it. Although it is most commonly seen in children, adults can contract this infection. Rashes, small painful blisters, fever, sore throat, and body pain are all common symptoms. This disease is treated with antiviral medications. Avoid contact with other people who have chickenpox and practise good hygiene to recover quickly.