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Written By aquibnaseer ,
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Manufacturer/Marketer :

Geolife Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

About Vasrate F 10mg/160mg Tablet

Vasrate F 10mg/160mg Tablet belongs to the class of medicines called antilipemic (lipid-lowering medicines) primarily used in the treatment of high lipid levels (cholesterol and triglycerides levels) and prevention of heart diseases and blood vessel blockage. Hyperlipidemia or hypertriglyceridemia is a condition in which there is a high level of low-density lipoproteins (LDL) or bad cholesterol and a decreased level of high-density lipoprotein (HDL) or good cholesterol. Increased level of bad cholesterol leads to a high risk of heart attack and stroke in the future, especially in patients with heart disease. 

Vasrate F 10mg/160mg Tablet is composed of two medicines, namely: Atorvastatin (HMG-CoA reductase inhibitor) and Fenofibrate (fibrates). Atorvastatin is a lipid-lowering medication that blocks the enzyme HMG-CoA reductase required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL), and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Fenofibrate is another lipid-lowering agent which works by increasing the natural substance (lipoprotein lipase) that breaks down fats in the bloodstream thereby increasing its utilization and removal. As a result, it decreases harmful cholesterol like LDL (bad cholesterol), and triglycerides (TG) and increases levels of HDL (good cholesterol). 

Take Vasrate F 10mg/160mg Tablet as prescribed. Your doctor will advise how often you take Vasrate F 10mg/160mg Tablet based on your medical condition. In some cases, you may experience allergic reactions, hyperglycemia (excess of glucose in the bloodstream), headache, blurred vision, stomach pain, constipation, headaches, joint swelling (edema), joint pain, muscle pain, back pain, slow heart rate, and nausea. Most of these side effects of Vasrate F 10mg/160mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

If you are allergic to Vasrate F 10mg/160mg Tablet or any component present in it namely atorvastatin or fenofibrate, please tell your doctor. If you are pregnant or breastfeeding, have hypothyroidism, drink more than 2 servings of alcohol per day, and have a muscle disorder (fibromyalgia) it is advised to inform your doctor before using Vasrate F 10mg/160mg Tablet. Vasrate F 10mg/160mg Tablet is not recommended for children below  12 years of age, as the safety and effectiveness were not established. If you experience yellowing of the skin (Jaundice), allergic reaction, cramps, or muscle weakness then immediately contact your doctor.

Uses of Vasrate F 10mg/160mg Tablet

Treat high lipid levels and reduce the risk of heart diseases

Directions for Use

Take Vasrate F 10mg/160mg Tablet with or without food as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, chew or crush it.

Medicinal Benefits

Vasrate F 10mg/160mg Tablet taken with dietary measures helps in the treatment of high cholesterol and prevention of life-threatening conditions to the heart, especially for heart patients when initial dietary measures fail to lower cholesterol. It helps in lowering the bad cholesterol (LDL) and increases the level of good cholesterol (HDL) in the state of dyslipidemia or hyperlipidemia. Vasrate F 10mg/160mg Tablet also lowers the amount of fat or cholesterol deposition (plaque) in the arteries of the heart thereby reducing the chance of having a heart attack or stroke in the future.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

A patient should consult a doctor before taking Vasrate F 10mg/160mg Tablet if a patient has had a previous stroke with bleeding into the brain or have small pockets of fluid in the brain from previous strokes, or has kidney problems. has under-active thyroid gland (hypothyroidism), has repeated or unexplained muscle aches or pains, has a personal history or family history of muscle problems, has previous muscular problems during treatment with other lipid-lowering medicines (e.g. other ‘-statin’ or ‘-fibrate’ medicines),  drinks a large amount of alcohol, has a history of liver disease, is older than 70 years,  has diabetes, especially Type 2 diabetes, that is not well controlled or has problems with certain proteins in your blood.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Vasrate F 10mg/160mg Tablet:
Taking Vasrate F 10mg/160mg Tablet with Posaconazole can increase the blood levels of Vasrate F 10mg/160mg Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Vasrate F 10mg/160mg Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vasrate F 10mg/160mg Tablet:
Combining Vasrate F 10mg/160mg Tablet with darunavir may profoundly enhance Vasrate F 10mg/160mg Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Taking Vasrate F 10mg/160mg Tablet with darunavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vasrate F 10mg/160mg Tablet:
Co-administration of Vasrate F 10mg/160mg Tablet with Clarithromycin possibly enhances Vasrate F 10mg/160mg Tablet levels in the blood. This can raise the chance of side effects (liver damage and rhabdomyolysis, an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with Vasrate F 10mg/160mg Tablet if prescribed by the doctor. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
AtorvastatinSaquinavir
Severe
How does the drug interact with Vasrate F 10mg/160mg Tablet:
Taking Vasrate F 10mg/160mg Tablet with saquinavir may significantly enhance Vasrate F 10mg/160mg Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury0.

How to manage the interaction:
Co- administration of Vasrate F 10mg/160mg Tablet with saquinavir can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Vasrate F 10mg/160mg Tablet:
Coadministration of Vasrate F 10mg/160mg Tablet with lenalidomide can increase the risk of rhabdomyolysis (a rare condition that results in skeletal muscle tissue damage).

How to manage the interaction:
Although there is an interaction between Vasrate F 10mg/160mg Tablet and lenalidomide, it can be taken if a doctor has advised it. However, if you experience unexplained muscle pain, tenderness, or weakness accompanied by fever, dark-coloured urine, or light-coloured stools, consult a doctor immediately. breath. Do not discontinue any medications without consulting a doctor.
AtorvastatinConivaptan
Severe
How does the drug interact with Vasrate F 10mg/160mg Tablet:
Using conivaptan together with Vasrate F 10mg/160mg Tablet may significantly increase the blood levels of Vasrate F 10mg/160mg Tablet.

How to manage the interaction:
Taking Vasrate F 10mg/160mg Tablet with Conivaptan together can result in an interaction, but it can be taken if a doctor has advised it. You should also seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
AtorvastatinLomitapide
Severe
How does the drug interact with Vasrate F 10mg/160mg Tablet:
Coadministration of Vasrate F 10mg/160mg Tablet with Lomitapide may increase the blood levels of lomitapide.

How to manage the interaction:
There may be a possibility of interaction between Vasrate F 10mg/160mg Tablet and Lomitapide, but it can be taken if prescribed by a doctor. Seek immediate medical attention if you develop signs and symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
AtorvastatinNefazodone
Severe
How does the drug interact with Vasrate F 10mg/160mg Tablet:
Using Vasrate F 10mg/160mg Tablet together with nefazodone may significantly increase the blood levels of Vasrate F 10mg/160mg Tablet.

How to manage the interaction:
Taking Vasrate F 10mg/160mg Tablet with Nefazodone together can result in an interaction, but it can be taken if a doctor has advised it. You should seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes. Do not stop using any medications without a doctor's advice.
How does the drug interact with Vasrate F 10mg/160mg Tablet:
Using Vasrate F 10mg/160mg Tablet together with danazol may significantly increase the blood levels of Vasrate F 10mg/160mg Tablet.

How to manage the interaction:
Concomitant administration of Vasrate F 10mg/160mg Tablet along with danazol can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness, accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop taking any medication without doctor's advice.
AtorvastatinNelfinavir
Severe
How does the drug interact with Vasrate F 10mg/160mg Tablet:
Taking Vasrate F 10mg/160mg Tablet with nelfinavir may considerably raise Vasrate F 10mg/160mg Tablet levels in the blood. This can raise the chance of side effects (liver injury and rhabdomyolysis - an uncommon but serious illness that causes the breakdown of skeletal muscle tissue. Rhabdomyolysis occasionally results in kidney injury).

How to manage the interaction:
Although taking Vasrate F 10mg/160mg Tablet and cyclosporine together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ATORVASTATIN-10MG+FENOFIBRATE-160MGFruit juices
Moderate

Drug-Food Interactions

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ATORVASTATIN-10MG+FENOFIBRATE-160MGFruit juices
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Blood levels of atorvastatin can rise after consuming grapefruit juice. Before quitting the drug, speak to a doctor even though there may be an interaction. Additionally, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, or yellowing of the skin or eyes, you should consult a doctor. Without first consulting your doctor, never stop taking the medication.

Diet & Lifestyle Advise

  • Eating a proper diet (such as a low-cholesterol/low-fat diet), other lifestyle changes that may help this medication work better include exercising, losing weight if overweight, and stopping smoking.
  • It is best to limit or avoid alcoholic drinks while you are taking this medicine.
  • Using this medicine with alcohol can lead to additive side effects such as increased drowsiness. Do not drive or operate machinery if you are drinking alcohol-containing beverages.
  • If you notice slurred speech, confusion, severe weakness or difficulty breathing, contact your health care provider immediately.
  • Try aromatherapy, yoga, and meditation to help relax your body and mind.
  • Try to do breathing exercises to get more oxygen.
  • Eat a healthy diet especially rich in soluble fibers like beans, legumes, whole grains, flax, apples, and citrus fruits.
  • Try to replace most of your saturated fats with unsaturated fats that can reduce total cholesterol and LDL cholesterol in a short period. Foods like avocados, olive oil, fatty fish, and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Try to adopt a Mediterranean-style diet rich in olive oil, fruits, vegetables, nuts, whole grains, and fish, and lower the consumption of red meat.
  • Try to give priority to more fruits and veggies in your daily meal as these contain antioxidants that help to lower LDL.

Habit Forming

No

Therapeutic Class

ANTILIPEMICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Take the missed dose as soon as possible or skip to the next dose if it's been too late. Never try to take a double dose to make up for the missed dose.

Strictly no, a patient is advised to take proper healthy diet free of oily and fatty products recommended by doctor for the best results of this medication.

As such no harmful interaction has been reported yet doctors consultation is advised.

This drug is primarily used to lower high levels of fatty acids in blood & to use it for weightloss is only done on doctors recommendation after he/she thoroughly checks the state of patient.

Certain antibiotics like erythromycin and clarithromycin interacts with Vasrate F 10mg/160mg Tablet and hence should not be used simultaneously with Vasrate F 10mg/160mg Tablet,unless consulted & recommended by a doctor.

Drug-Drug Interactions Checker List

  • TETRACYCLINE
  • GENTAMICIN
  • MICONAZOLE
  • FLUCONAZOLE
  • CYCLOSPORINE
  • VERAPAMIL
  • DILTIAZEM

Disease/Condition Glossary

The cholesterol in blood comes from two sources: the foods you eat and the liver. The liver makes all the cholesterol that is essential for healthy cell membranes, brain functioning, hormone production, and vitamin storage. Excess cholesterol is bad for health. There are two types of cholesterol namely 'bad cholesterol' and 'good cholesterol. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG) while good cholesterol consists of high-density lipoprotein (HDL). Usually, there are no specific symptoms of raised or high levels of cholesterol but a large deposition of cholesterol in the arteries (plaque) of the heart. Blocked artery or plaque formation in the arteries of the heart can lead to chest pain, heart attack, or stroke. 

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