VELCADE 1MG INJECTION

Written By Bayyarapu Mahesh Kumar , M Pharmacy

Reviewed By Sureshvarma D , MPharma

MRP ₹18060

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Whats That

About VELCADE 1MG INJECTION

VELCADE 1MG INJECTION belongs to a group of anti-cancer medicines used to treat adult patients with multiple myeloma and mantle cell lymphoma who have received at least one prior therapy. Multiple myeloma, also known as myeloma, is a type of bone marrow cancer it affects several areas of the body, such as the spine, skull, pelvis, and ribs. Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma (NHL). It develops when B-cells (also called B-lymphocytes) become abnormal. B-cells are white blood cells that fight infection.

VELCADE 1MG INJECTION contains 'Bortezomibx' that works by interfering with how proteasomes work, which may cause cancer cells to die and may stop cancer from growing and eventually kills them.

VELCADE 1MG INJECTION is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection into your vein (intravenously or IV) or under your skin (subcutaneously or SC). VELCADE 1MG INJECTION must not be administered into your spinal fluid (intrathecally). You may experience nausea, diarrhoea, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), peripheral neuropathy (nerves malfunction), fatigue, neuralgia, anaemia, leukopenia, constipation, vomiting, lymphopenia, rash, pyrexia, and anorexia. Most of these side effects of VELCADE 1MG INJECTION do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

To treat your condition effectually, continue taking VELCADE 1MG INJECTION for as long as your doctor has prescribed. Do not stop the VELCADE 1MG INJECTION midway. Talk to your doctor before taking VELCADE 1MG INJECTION if you have allergies or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. Avoid taking VELCADE 1MG INJECTION if you are pregnant or breastfeeding because this VELCADE 1MG INJECTION can cause harmful effects on the unborn baby. Both women and men using this VELCADE 1MG INJECTION should use birth control to avoid pregnancy.

Uses of VELCADE 1MG INJECTION

Multiple myeloma and Mantle cell lymphoma.

Directions for Use

VELCADE 1MG INJECTION will be administered by a qualified healthcare professional. Kindly do not self-administer.

Medicinal Benefits

VELCADE 1MG INJECTION contains the active substance bortezomib, also-called ‘proteasome inhibitor. Proteasomes play an important role in controlling cell function and growth. By interfering with their function, thereby it can kill cancer cells. VELCADE 1MG INJECTION is used to treat multiple myeloma (a cancer of the bone marrow) and mantle cell lymphoma (a type of cancer affecting the lymph nodes) in 18 years or older patients. It can be used alone or together with other medicines.

Storage

Keep VELCADE 1MG INJECTION out of the sight and reach of children.

Side effects of Velcade 1mg Injection

Low Platelet Count

Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Increased Risk Of Infection Due To Low Neutrophil Count

Talk to your doctor about medicines to manage neutropenia based on the underlying cause.
Avoid contact with people who are sick.
Wash your hands regularly with soap and water.
Avoid unpasteurized dairy products.

Anemia

Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
Consume vitamin C-rich foods as they aid iron absorption.
Limit tea, cocoa, and coffee as these can slow iron absorption.
Exercise regularly; however, do not overdo it.

Low White Blood Cell Count

Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
Get sufficient sleep and manage stress which helps in improving white blood cell count.
Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Low Levels Of Lymphocytes (A Type Of White Blood Cells)

Nourish your body with a balanced diet with protein-rich foods like fish, eggs, and beans. Fruits, vegetables, and nuts provide essential vitamins and minerals. If necessary, consider vitamin B12 and folate supplements.
Practice good hygiene to protect yourself from infections. Wash your hands often, stay up-to-date on vaccinations, avoid crowded areas, and take care when handling food, pets, and diapers.
Aim for a good night's sleep, targeting 8 hours of sleep. Find calm through stress-reducing practices like yoga, meditation, or deep breathing. Regular physical activity can also help.
Stay healthy by drinking plenty of water, eating probiotic-rich foods like yoghurt, and limiting processed foods and sugars. Consult your doctor, if you are having difficulties or concerns.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

To treat your condition effectually, continue taking VELCADE 1MG INJECTION for as long as your doctor has prescribed. Do not stop the VELCADE 1MG INJECTION midway. Talk to your doctor before taking VELCADE 1MG INJECTION if you have allergies or if you are suffering from peripheral neuropathy (nerves malfunction), hypotension, cardiac disorders, severe lung problems, pulmonary disorders, posterior reversible encephalopathy syndrome disorders, gastrointestinal disorders, thrombocytopenia (a low platelet count), neutropenia (low white blood cell count), tumour lysis syndrome (metabolic abnormalities that can occur as a complication during the treatment of cancer), hepatic disorders. And also, inform your doctor if you have diabetes because this medicine can affect your blood glucose levels. Your doctor may require close monitoring of your blood glucose levels and change your diabetes medicine dose while being treated with VELCADE 1MG INJECTION. Avoid taking VELCADE 1MG INJECTION if you are pregnant because this VELCADE 1MG INJECTION can cause harmful effects on the unborn baby. Both women and men using this VELCADE 1MG INJECTION should use birth control to avoid pregnancy and for at least six months following treatment. Do not breastfeed during treatment with VELCADE 1MG INJECTION and four months after your final dose of VELCADE 1MG INJECTION.

Drug-Drug Interactions

BortezomibCertolizumab

Severe

BortezomibRifabutin

Severe

Drug-Drug Interactions

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BortezomibCertolizumab

Severe

How does the drug interact with Velcade 1mg Injection:
Coadministration of certolizumab and Velcade 1mg Injection may increase the risk of infections.

How to manage the interaction:
Although using Velcade 1mg Injection and Certolizumab together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, diarrhoea, sore throat, muscle aches, red or irritated skin, or burning during urination. Do not stop taking any medications without consulting a doctor.

BortezomibRifabutin

Severe

How does the drug interact with Velcade 1mg Injection:
Coadministration of Velcade 1mg Injection and rifabutin may reduce the blood levels of Velcade 1mg Injection.

How to manage the interaction:
Although using Velcade 1mg Injection and Rifabutin together can possibly result in an interaction, they can be taken together if prescribed by a doctor. Do not stop taking any medications without consulting a doctor.

BortezomibTalimogene laherparepvec

Severe

How does the drug interact with Velcade 1mg Injection:
Taking Velcade 1mg Injection together with talimogene laherparepvec increases the risk of developing infection.

How to manage the interaction:
Although using Velcade 1mg Injection and Talimogene laherparepvec together can possibly result in an interaction, they can be taken together if advised by your doctor. Do not stop taking any medications without consulting a doctor.

BortezomibNatalizumab

Severe

How does the drug interact with Velcade 1mg Injection:
Coadministration of Velcade 1mg Injection and natalizumab can increase the risk of infections.

How to manage the interaction:
Although using Velcade 1mg Injection and natalizumab together can result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, joint pain, or burning during urination. Do not stop taking any medications without consulting a doctor.

BortezomibGolimumab

Severe

How does the drug interact with Velcade 1mg Injection:
Coadministration of golimumab and Velcade 1mg Injection may increase the risk of infections.

How to manage the interaction:
Although using Velcade 1mg Injection and Golimumab together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, red or irritated skin, discomfort, or burning during urination. Do not stop taking any medications without consulting a doctor.

BortezomibTofacitinib

Severe

How does the drug interact with Velcade 1mg Injection:
Taking tofacitinib and Velcade 1mg Injection may increase the risk of infections.

How to manage the interaction:
Although using Velcade 1mg Injection and Tofacitinib together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, diarrhea, sore throat, muscle aches, red or irritated skin, or burning during urination. Do not stop taking any medications without consulting a doctor.

BortezomibLomitapide

Severe

How does the drug interact with Velcade 1mg Injection:
Coadministration of lomitapide and Velcade 1mg Injection can increases the risk of liver problems.

How to manage the interaction:
Although using Velcade 1mg Injection and Lomitapide together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, joint pain or swelling, skin rash, itching, abdominal pain, dark urine, light stools, and/or yellowing of the skin or eyes. Do not stop taking any medications without consulting a doctor.

BortezomibSamarium (153sm) lexidronam

Severe

How does the drug interact with Velcade 1mg Injection:
Using samarium (153sm) lexidronam together with Velcade 1mg Injection may increase the risk of side effects

How to manage the interaction:
Co-administration of Velcade 1mg Injection with Samarium (153sm) lexidronam can possibly result in an interaction; they can be taken if your doctor has advised it. However, consult a doctor if you experience fatigue, dizziness, fever, chills, diarrhea, sore throat, muscle aches, red or inflamed skin, and pain or burning during urination. Do not stop using any medications without a doctor's advice.

BortezomibPrimidone

Severe

How does the drug interact with Velcade 1mg Injection:
Coadministration of Velcade 1mg Injection and primidone may reduce the blood levels of Velcade 1mg Injection, which may make the medication less effective in treating your condition.

How to manage the interaction:
Although using Velcade 1mg Injection and Primidone together can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.

BortezomibClozapine

Severe

How does the drug interact with Velcade 1mg Injection:
Coadministration of clozapine with Velcade 1mg Injection may increase the risk of infections.

How to manage the interaction:
Although using Velcade 1mg Injection and Clozapine together can possibly result in an interaction, they can be taken together if advised by your doctor. However, contact a doctor if you experience fever, chills, diarrhoea, sore throat, muscle aches, red or irritated skin, or burning during urination. Do not stop taking any medications without consulting a doctor.

Drug-Food Interactions

BORTEZOMIB-1MGCaffeine containing foods/drinks, Fiber rich foods

Moderate

Drug-Food Interactions

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BORTEZOMIB-1MGCaffeine containing foods/drinks, Fiber rich foods

Moderate

Common Foods to Avoid:
Green Tea, Oranges

How to manage the interaction:
Vitamin C or vitamin-containing foods and green tea diminish the effectiveness of Velcade 1mg Injection Avoid or limit the consumption of Vitamin C or vitamin-containing foods and green tea.

Diet & Lifestyle Advise

Eat a healthy diet and exercise regularly to maintain proper weight.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
Get optimal sleep, and rest well.
Performing yoga may also help in improving both physical and mental health.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
Avoid smoking and alcohol consumption.
Avoid fast, fried, processed meats, refined carbs, and added sugars.

Side Effects of VELCADE 1MG INJECTION

Nausea
Diarrhoea
Thrombocytopenia (low blood platelet count)
Neutropenia (too few neutrophils)
Peripheral neuropathy (nerves malfunction)
Fatigue (overtired)
Neuralgia (pain in the head or face)
Muscle pain, bone pain
Anaemia (low red blood cell Count)
Leukopenia (Low White Blood Cell Count)
High blood pressure
Constipation
Dehydration
Vomiting
Loss of appetite
Lymphopenia (Low lymphocytes Count)
Rash
Pyrexia (raised body temperature)
Anorexia (lack or loss of appetite for food)
Infections, including pneumonia, respiratory infections, bronchitis, fungal infections, coughing with phlegm, flu-like illness

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Author Details

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:37 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does VELCADE 1MG INJECTION work?

VELCADE 1MG INJECTION contains the active substance bortezomib, also-called ‘proteasome inhibitor. Proteasomes play an important role in controlling cell function and growth. By interfering with their function, thereby it can kill cancer cells.

How and who will be eligible to give the VELCADE 1MG INJECTION?

VELCADE 1MG INJECTION is prescribed by a doctor experienced in the use of medications to treat cancer. It is administered by a healthcare professional as an injection into your vein (intravenously or IV) or under your skin (subcutaneously, or SC). VELCADE 1MG INJECTION must not be administered into your spinal fluid (intrathecally).

Does VELCADE 1MG INJECTION cause lower white blood cells (neutropenia)?

Yes, VELCADE 1MG INJECTION can cause low neutrophils levels, a type of white blood cells that help fight infections. If your white blood cells become low, you can be at higher risk for infections. Tell your doctor if you develop a fever or believe you have an infection.

I am pregnant, can I take VELCADE 1MG INJECTION?

Avoid taking VELCADE 1MG INJECTION if you are pregnant because VELCADE 1MG INJECTION can cause harmful effects on the unborn baby. Females should follow effective birth control methods during treatment and at least six months after the final dose of VELCADE 1MG INJECTION.

Who should not receive VELCADE 1MG INJECTION?

Before you receive treatment with VELCADE 1MG INJECTION, tell your doctor about all of your medical conditions. You should not receive VELCADE 1MG INJECTION if you are allergic to bortezomib or any contents in VELCADE 1MG INJECTION.

Is VELCADE 1MG INJECTION poisonous?

If not given an inappropriate dose, VELCADE 1MG INJECTION can cause toxic effects, although not everyone gets it. So, VELCADE 1MG INJECTION is prescribed by a doctor experienced in using medications to treat cancer only.

Drug-Drug Interactions Checker List

KETOCONAZOLE
RITONAVIR
RIFAMPICIN
CARBAMAZEPINE
PHENYTOIN
PHENOBARBITAL

Special Advise

VELCADE 1MG INJECTION should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking VELCADE 1MG INJECTION.
Your doctor may get routine blood tests done to monitor your liver function, electrolyte levels, blood cell count in your blood.
Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. VELCADE 1MG INJECTION may make your skin sensitive to sunlight.

Disease/Condition Glossary

Multiple myeloma, also known as myeloma, is a type of bone marrow cancer it affects several areas of the body, such as the spine, skull, pelvis, and ribs.

Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma (NHL). It develops when B-cells (also called B-lymphocytes) become abnormal. B-cells are white blood cells that fight infection.

Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can invade and destroy surrounding healthy tissue, including organs.