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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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About Verzen DP Tablet

Verzen DP Tablet belongs to the class of combination medication called NSAIDs (non-steroidal anti-inflammatory drugs) used to relieve pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis. Besides this, it also helps treat muscle pain, tooth pain during dental surgery, menstrual period pain/cramps, ear pain and migraine headaches. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Arthritis is the tenderness and swelling in the joints which causes pain and joint stiffness.

Verzen DP Tablet is a combination of three drugs, namely: Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of a chemical messenger, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. These prostaglandins are produced at injury sites and cause pain, swelling and fever. By blocking COX enzyme's effect, lesser prostaglandins are produced, which reduces mild to moderate pain, inflammation and fever. Serratiopeptidase acts as a mucolytic (dissolves thick protein at the injured/affected site) and anti-inflammatory agent thereby decreasing swelling at the painful site. 
 
You are advised to take Verzen DP Tablet for as long as your doctor has prescribed it for you. In some cases, Verzen DP Tablet may cause certain common side-effects such as nausea, vomiting, stomach pain, headache, indigestion and diarrhoea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Verzen DP Tablet may cause drowsiness and dizziness, so drive with caution. Verzen DP Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol with Verzen DP Tablet as it could lead to increased drowsiness and dizziness; it might also increase the risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Verzen DP Tablet

Pain and inflammation associated with osteoarthritis, muscle pain, joint pain, rheumatoid arthritis, mild migraine, dental pain, etc.

Directions for Use

Take Verzen DP Tablet with food. Swallow Verzen DP Tablet as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Verzen DP Tablet is a combination of three drugs, namely: Diclofenac (pain killer), Paracetamol (fever reducer) and Serratiopeptidase (protein enzyme). Verzen DP Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, headache, swelling, period pain, ear pain, migraine, fever,  sore throat, nose pain, etc. Verzen DP Tablet increases the pain threshold and blood flow across the skin. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase breaks down the abnormal proteins at the site of inflammation, thereby reduces inflammation. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Verzen DP Tablet if you are allergic to paracetamol, diclofenac or serratiopeptidase, have/had severe heart problems, stomach ulcer or perforation, bleeding problems such as bleeding from the stomach, intestine or brain, have undergone any heart bypass surgery, have had a heart attack, blood circulation problems or inflammation of intestines. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding. Verzen DP Tablet may cause drowsiness and dizziness, so drive only if you are alert. Verzen DP Tablet is not recommended for children less than 10 years of age as safety and effectiveness have not been established. Avoid consuming alcohol with Verzen DP Tablet as it could lead to increased drowsiness and increased risk of stomach bleeding. Stop taking Verzen DP Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Verzen DP Tablet unless prescribed.

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
ParacetamolLomitapide
Severe

Drug-Drug Interactions

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DiclofenacMeloxicam
Critical
How does the drug interact with Verzen DP Tablet:
Co-administration of Verzen DP Tablet with Meloxicam can increase the risk or severity of gastrointestinal side effects.

How to manage the interaction:
Taking Meloxicam with Verzen DP Tablet is not recommended as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness. Do not stop any medication without doctor's advise.
ParacetamolLomitapide
Severe
How does the drug interact with Verzen DP Tablet:
Co-administration of Lomitapide and Verzen DP Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Verzen DP Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetoconazole
Severe
How does the drug interact with Verzen DP Tablet:
Co-administration of Verzen DP Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Verzen DP Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Verzen DP Tablet:
Co-administration of Mipomersen with Verzen DP Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Verzen DP Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ParacetamolValdecoxib
Severe
How does the drug interact with Verzen DP Tablet:
Co-administration of Verzen DP Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Verzen DP Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolOxazepam
Severe
How does the drug interact with Verzen DP Tablet:
Co-administration of Verzen DP Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Verzen DP Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolKetamine
Severe
How does the drug interact with Verzen DP Tablet:
Co-administration of ketamine and Verzen DP Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Verzen DP Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolTeriflunomide
Severe
How does the drug interact with Verzen DP Tablet:
Co-administration of Teriflunomide with Verzen DP Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Verzen DP Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Verzen DP Tablet:
Co-administration of Verzen DP Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Verzen DP Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DiclofenacWarfarin
Severe
How does the drug interact with Verzen DP Tablet:
Taking Verzen DP Tablet with warfarin may, increase the risk of bleeding.

How to manage the interaction:
There may be a possible interaction between Verzen DP Tablet and Warfarin, but they can be taken together if a doctor has prescribed them. However, consult your doctor immediately if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes; instead, wear loose garments.
  • Rest well, and get plenty of sleep.
  • To avoid developing pressure sores, change your position every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20 minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Verzen DP Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Verzen DP Tablet contains Diclofenac, Paracetamol and Serratiopeptidase. Diclofenac and Paracetamol work by blocking the effect of chemical messengers that cause pain and inflammation. Serratiopeptidase is a protein enzyme that helps break down and dissolves the abnormal proteins at the inflammation site, thereby reducing pain.

Verzen DP Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.

Diarrhoea might be a side-effect of Verzen DP Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Verzen DP Tablet should not be taken for longer durations unless prescribed by the doctor. If Verzen DP Tablet has been prescribed for longer durations, regular monitoring of kidney function, liver function and blood count is advised, particularly in elderly patients.

Avoid taking Verzen DP Tablet if you have ulcers in the stomach or intestines, bleeding problems or heart problems.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CYCLOSPORINE
  • TACROLIMUS
  • LITHIUM
  • DIGOXIN
  • WARFARIN
  • METHOTREXATE
  • MAGNESIUM HYDROXIDE
  • KETOCONAZOLE
  • MICONAZOLE
  • VORICONAZOLE
  • FLUCONAZOLE
  • AMIDODARONE
  • SULFINPYRAZONE
  • METOCLOPRAMIDE
  • DOMPERIDONE
  • CHOLESTYRAMINE
  • IMATINIB
  • CHLORAMPHENICOL
  • MIFEPRESTONE

Disease/Condition Glossary

Pain: Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp, it might be constant or may come and go. The tolerance level of pain might vary from person to person. Pain can be generalized (overall body aches) or localized (affecting a specific area of the body). The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures and arthritis.

Osteoarthritis: It is a joint disease in which the two ends of the joints come together due to the breakdown of a protective covering called cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms include pain, stiffness, inflammation and tenderness.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities and loss of joint function. 

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain generally starts in the lower back and can spread to the neck, damaged joints or other body parts. Ankylosing spondylitis includes decreased flexibility which usually leads to a hunched-forward posture and pain in the back and joints.

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