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Whats That
About VIROTRENZ TABLET
VIROTRENZ TABLET belongs to the class of medicines called ‘antiretroviral agents’ used to treat HIV infection. HIV is a virus that attacks the immune cells of the body leading to decreased immunity. It spreads through body fluids such as semen, vaginal fluid, and blood. Symptoms include fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat that usually last for days to several weeks.
VIROTRENZ TABLET contains Efavirenz, Emtricitabine, and Tenofovir. Efavirenz is a non-nucleoside reverse transcriptase inhibitor, whereas Emtricitabine and Tenofovir are nucleotide reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme production, which the HIV-infected cells must make to make new viruses. This effect helps to inhibit viral replication.
You should take this medicine exactly as prescribed by the doctor. The common side-effects of VIROTRENZ TABLET are dizziness, headache, diarrhea, feeling sick (nausea), being sick (vomiting), rashes (red spots or blotches sometimes with blistering and swelling of the skin), and feeling weak. These side-effects usually resolve without requiring any medical attention. However, if any of these side effects persist or get worse, inform your doctor immediately.
It is not recommended to take VIROTRENZ TABLET if you are allergic to any contents of it. Do not take VIROTRENZ TABLET if you have severe liver disease, moderate to severe kidney disease, heart condition such as prolongation of the QT interval, which increases the risk of severe heart rhythm problems, family history of heart problems, and low electrolyte levels. It is not recommended for use in children and adolescents under 18 years of age. It should be used with caution in pregnant women, breastfeeding mothers, and elderly people. Consumption of alcohol may increase the risk of side effects. VIROTRENZ TABLET may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Uses of VIROTRENZ TABLET
Directions for Use
Medicinal Benefits
VIROTRENZ TABLET belongs to the group of medicines called antiretroviral therapy (ART). VIROTRENZ TABLET is a fixed-dose combination (FDC) and contains Efavirenz, Emtricitabine, and Tenofovir. FDC helps decrease drug resistance (reducing medication effectiveness) as the HIV virus can easily develop drug resistance. VIROTRENZ TABLET helps reduce the symptoms, control the infection, and prevent opportunistic infections effectively. It further helps in improving the quality of life of a patient with HIV.
Storage
Drug Warnings
VIROTRENZ TABLET may affect kidney function, so it is advised to monitor kidney function while using this medicine. VIROTRENZ TABLET should be used with caution in patients with mental illness, fits, liver diseases, VIROTRENZ TABLET may decrease phosphate levels in the blood. It may also increase creatine kinase (CK) levels (high CK levels indicate muscle being destroyed) in the blood resulting in muscle pain and weakness. VIROTRENZ TABLET show signs of infection or inflammation from the previous infection when the treatment has started in some patients with advanced HIV infection and history of opportunistic infection. So, if you notice any signs of infection, inform your doctor immediately. Autoimmune diseases (immune cells attack healthy body tissue) may occur months after the start of the treatment. Inform your doctor if you notice any signs such as muscle weakness, weakness in the hands and the feet, palpitations (pounding heart), and tremors. VIROTRENZ TABLET may cause osteonecrosis (death of bone tissue due to a decrease in blood supply to the bone) in some patients. The risk of this disease depends on factors such as length of antiretroviral therapy, alcohol use, steroid use, body mass index (BMI), and immunity. Inform your doctor if you notice joint pain, stiffness, and difficulty in movement, as these symptoms may indicate osteonecrosis.
Drug-Drug Interactions
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Side Effects of VIROTRENZ TABLET
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Therapeutic Class
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VIROTRENZ TABLET contains Efavirenz, Emtricitabine, and Tenofovir. Efavirenz is a non-nucleoside reverse transcriptase inhibitor, whereas Emtricitabine and Tenofovir are nucleotide reverse transcriptase inhibitors. They work by inhibiting the reverse transcriptase enzyme production, which the HIV-infected cells must make to make new viruses. This effect helps to inhibit viral replication.
VIROTRENZ TABLET should be taken on an empty stomach 1 hour before or 2 hours after a meal, preferably at bedtime, as this medicine may cause dizziness or drowsiness.
The common side-effects of VIROTRENZ TABLET are dizziness, headache, diarrhea, feeling sick (nausea), being sick (vomiting), rashes (red spots or blotches sometimes with blistering and swelling of the skin), and feeling weak. These side-effects usually resolve without requiring any medical attention. However, if any of these side effects persist or get worse, inform your doctor immediately.
VIROTRENZ TABLET should not be given to patients with severe liver disease, moderate to severe kidney disease, heart condition such as prolongation of the QT interval which increases the risk of severe heart rhythm problems, family history of heart problems, and low electrolyte levels.
VIROTRENZ TABLET doesn’t cure HIV infection. However, it helps to control the disease and prevent opportunistic infections.
Drug-Drug Interactions Checker List
Special Advise
Disease/Condition Glossary
HIV infection: HIV (human immunodeficiency virus) is a virus that attacks the immune system, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. It spreads through body fluids such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral agents.
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Alcohol
Caution
Consumption of alcohol may increase the risk of side-effects.
Pregnancy
Caution
VIROTRENZ TABLET should be used with caution in pregnant women. It is given only if clinically needed and when benefits outweigh the risk.
Breast Feeding
Caution
VIROTRENZ TABLET should be used with caution in breastfeeding women. If VIROTRENZ TABLET is prescribed during breastfeeding, the doctor may advise you to stop breastfeeding as this medicine can pass into breastmilk.
Driving
Caution
VIROTRENZ TABLET may cause dizziness, so do not drive or operate heavy machinery if you feel dizzy.
Liver
Caution
VIROTRENZ TABLET should not be used with caution in patients with severe liver diseases. In mild to moderate conditions, the dose may have to be adjusted by your doctor as required.
Kidney
Caution
VIROTRENZ TABLET should not be used in patients with moderate to severe kidney diseases as this medicine may affect kidney function. In mild conditions, the dose may have to be adjusted by your doctor as required.
Children
Unsafe
VIROTRENZ TABLET is not recommended for use in children and adolescents below 18 years.