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About Vokanamet 50mg/500mg Tablet 60's

Vokanamet 50mg/500mg Tablet 60's belongs to the class of antidiabetic drugs, primarily used to treat type 2 diabetes mellitus with a proper diet and exercise. Vokanamet 50mg/500mg Tablet 60's also lowers the risk of heart attack, stroke or heart failure in type 2 diabetic patients with heart diseases. Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produce little or no insulin at all. Vokanamet 50mg/500mg Tablet 60's is not indicated for use in type 1 diabetes.

Vokanamet 50mg/500mg Tablet 60's is composed of two antidiabetic medicines, namely: Metformin and Canagliflozin. Metformin belongs to the class of biguanides, which reduce increased blood glucose levels without increasing insulin secretion. Canagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine. 

Use Vokanamet 50mg/500mg Tablet 60's as advised by your doctor. Some common side effects of Vokanamet 50mg/500mg Tablet 60's include nausea, vomiting, diarrhoea, stomach pain, gas, headache, weakness, frequent urination and indigestion. Sometimes, Vokanamet 50mg/500mg Tablet 60's can cause side effects like lactic acidosis (a rare, but serious metabolic complication of excess lactic acid in the blood that is caused by metformin accumulation) and diabetic ketoacidosis (excess production of blood acids (ketones)). These side effects are not familiar to everyone and vary individually. If you notice any side effects that are not manageable, please consult your doctor. 

Vokanamet 50mg/500mg Tablet 60's may cause hypoglycaemia (low blood sugar), hence it advised to take healthy food with enough calories and avoid heavy exercises. Do not take or stop this medicine, if the doctor did not advise you to do so. Before starting Vokanamet 50mg/500mg Tablet 60's, let your doctor know if you have any medical history of heart, kidney or liver diseases, breathing problems, blood disorders, dehydration, alcohol use, low blood pressure and yeast infection of genitals. It is advised to avoid your alcohol intake while using Vokanamet 50mg/500mg Tablet 60's to decrease lactic acidosis risk. Vokanamet 50mg/500mg Tablet 60's is not recommended during pregnancy and breastfeeding. 

Uses of Vokanamet 50mg/500mg Tablet 60's

Type 2 Diabetes mellitus.

Directions for Use

Swallow it as a whole with a glass of water. Do not chew, crush or break it. Take it preferably with a meal, since it lowers the blood sugar levels and may cause gastrointestinal side effects. Your doctor may start the course with a low dose and gradually maintain an effective dose to achieve the required blood glucose control.

Medicinal Benefits

Vokanamet 50mg/500mg Tablet 60's treats type 2 diabetes mellitus and contains Metformin and Canagliflozin. Metformin is a biguanide and manages blood sugar levels. It exhibits a nonpancreatic effect to reduce blood glucose levels without increasing the insulin secretion. It is also known as insulin sensitizer as it increases the effects of insulin. Metformin is considered a unique antidiabetic drug since it does not cause hypoglycemia (lowered blood sugar levels). Canagliflozin belongs to the class of gliflozins. It works by reducing blood sugar levels by eliminating excess sugars from the body through urine. Canagliflozin reduces the risk of end-stage kidney disease in type 2 diabetic patients with renal impairment. Vokanamet 50mg/500mg Tablet 60's also reduces the risk of serious heart diseases, such as heart attack or stroke in patients with type 2 diabetes and heart disease. Vokanamet 50mg/500mg Tablet 60's may be advised with or without other medications along with diet and exercise to control blood sugar levels. 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Vokanamet 50mg/500mg Tablet 60's

  • Nausea
  • Vomiting
  • Diarrhoea
  • Stomach pain
  • Gas
  • Headache
  • Weakness
  • Frequent urination
  • Indigestion 
  • Lactic acidosis (rare)
  • Diabetic ketoacidosis (rare) 

Drug Warnings

Inform your doctor if you take other antidiabetic drugs to adjust the dosage of Vokanamet 50mg/500mg Tablet 60's accordingly. Do not abruptly stop taking Vokanamet 50mg/500mg Tablet 60's midway if the doctor did not advise you. Vokanamet 50mg/500mg Tablet 60's may cause hypoglycaemia (low blood sugar), hence it is advised to make healthy food with enough calories and avoid heavy exercises. Brief your medical history if you have any heart, kidney or liver diseases, breathing problems (asthma, obstructive lung diseases), blood problems like anaemia (lack of blood cells), vitamin B12 deficiency, dehydration, alcohol use, low blood pressure, mineral imbalance (high levels of potassium) and yeast infection of genitals. Avoid alcohol intake while using Vokanamet 50mg/500mg Tablet 60's since it may increase the risk of lactic acidosis. Canagliflozin in Vokanamet 50mg/500mg Tablet 60's may increase the risk of leg amputation (removal of the leg) in conditions like foot ulcers, heart diseases, circulation problems and nerve damage. Hence, it is advised to inform your doctor if you have any of these conditions before you start Vokanamet 50mg/500mg Tablet 60's. Vokanamet 50mg/500mg Tablet 60's is not recommended for use during pregnancy and breastfeeding. Your doctor may advise alternate medications to control your diabetic condition in such cases. Vokanamet 50mg/500mg Tablet 60's is not recommended for people younger than 18 years of age.  

Drug-Drug Interactions

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MetforminIofendylate
Critical
MetforminIopentol
Critical

Drug-Drug Interactions

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MetforminIofendylate
Critical
How does the drug interact with Vokanamet 50mg/500mg Tablet:
Co-administration of Iofendylate with Vokanamet 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vokanamet 50mg/500mg Tablet with Iofendylate is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIopentol
Critical
How does the drug interact with Vokanamet 50mg/500mg Tablet:
Co-administration of Iopentol with Vokanamet 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vokanamet 50mg/500mg Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Vokanamet 50mg/500mg Tablet:
Co-administration of Iopanoic acid with Vokanamet 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vokanamet 50mg/500mg Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIopamidol
Critical
How does the drug interact with Vokanamet 50mg/500mg Tablet:
Co-administration of Iopamidol with Vokanamet 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vokanamet 50mg/500mg Tablet with Iopamidol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIobitridol
Critical
How does the drug interact with Vokanamet 50mg/500mg Tablet:
Co-administration of Vokanamet 50mg/500mg Tablet and Iobitridol can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Vokanamet 50mg/500mg Tablet with Iobitridol is generally avoided as it can result in an interaction. Please consult your doctor before taking it.
MetforminIocetamic acid
Critical
How does the drug interact with Vokanamet 50mg/500mg Tablet:
Co-administration of Vokanamet 50mg/500mg Tablet and Iocetamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Vokanamet 50mg/500mg Tablet with Iocetamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Vokanamet 50mg/500mg Tablet:
Co-administration of Iotroxic acid with Vokanamet 50mg/500mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vokanamet 50mg/500mg Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminMetrizamide
Critical
How does the drug interact with Vokanamet 50mg/500mg Tablet:
Co-administration of Vokanamet 50mg/500mg Tablet with Metrizamide together can cause the risk of lactic acidosis (when the body produces too much lactic acid ).

How to manage the interaction:
Taking Vokanamet 50mg/500mg Tablet with Metrizamide is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience headaches, muscle cramps or pain, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetforminIodamide
Critical
How does the drug interact with Vokanamet 50mg/500mg Tablet:
Co-administration of Vokanamet 50mg/500mg Tablet and Iodamide can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Vokanamet 50mg/500mg Tablet with Iodamide is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Vokanamet 50mg/500mg Tablet:
Co-administration of Vokanamet 50mg/500mg Tablet with Iodamide may increase the risk of kidney problems.

How to manage the interaction:
Taking Vokanamet 50mg/500mg Tablet with Iodamide is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
  • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods, and avoiding carbonated drinks and foods that cause gas. 

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • HYDROCHLOROTHIAZIDE
  • PHENOBARBITAL
  • PHENYTOIN
  • CARBAMAZEPINE
  • RITONAVIR
  • EFAVIRENZ
  • RIFAMPIN
  • CHOLESTYRAMINE
  • DIGOXIN
  • DIGITOXIN
  • SALBUTAMOL
  • TERBUTALINE
  • IBUPROFEN
  • CELECOXIB
  • CIMETIDINE
  • DABIGATRAN

Special Advise

  • It is advised to monitor your blood sugar levels regularly.
  • If you need to undergo any x-ray or CT scan using a dye that should be injected into your veins, your doctor may suggest you to stop taking Vokanamet 50mg/500mg Tablet 60's temporarily.
  • Regular monitoring of kidney functioning is advised while using Vokanamet 50mg/500mg Tablet 60's.
  • Canagliflozin in Vokanamet 50mg/500mg Tablet 60's may make you test positive for a urine glucose test, hence inform your doctor in advance that you take Vokanamet 50mg/500mg Tablet 60's.

Disease/Condition Glossary

Diabetes mellitus 2, also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It is a type 2 diabetes and occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produce little or no insulin at all. This disease mostly occurs in people aged above 40 years, but can also occur in childhood based on the risk factors. The treatment includes oral glucose-lowering medicines and insulin shots.

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