VONADAY TABLET

Written By Divya L , PharmaD

Reviewed By Sureshvarma D , MPharma

MRP ₹3455.5

(Inclusive of all Taxes)

₹518.3 Cashback (15%)

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Prescription drug

Whats That

About VONADAY TABLET

VONADAY TABLET belongs to the class of ‘antiretrovirals,’ used to treat HIV infection. VONADAY TABLET helps in decreasing the chance of developing AIDS (acquired immunodeficiency syndrome). HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

VONADAY TABLET is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil. Efavirenz is a non-nucleoside reverse transcriptase inhibitor. Lamivudine is a nucleoside reverse transcriptase inhibitor. Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme, which is essential for the reproduction of the virus.

Your doctor will decide the dosage based on your medical condition. Sometimes, VONADAY TABLET may have common side effects like nausea, headache, dizziness, depression, sleeping problems, weakness, tiredness, cough, rash, unusual dreams, concentration problems, drowsiness (sleepiness), and diarrhoea. These side effects do not require medical attention and gradually resolve over time. However, if these side effects persist for a longer time, please seek medical advice.

Let your doctor know if you are using a prescription, non-prescription drugs, and herbal products before starting VONADAY TABLET. If you are known to be allergic to VONADAY TABLET or its inactive components, please inform your doctor. Please tell your doctor if you have any heart problems, liver or kidney diseases, alcohol addiction, fits, high cholesterol levels, and weak/broken bones. If you are pregnant, please consult your doctor before taking VONADAY TABLET. Do not breastfeed while taking VONADAY TABLET. VONADAY TABLET is recommended for children who weigh at least 77 pounds (35 kg).

Uses of VONADAY TABLET

HIV infection.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

VONADAY TABLET is used to treat HIV infection. It consists of three medicines, namely: Efavirenz, Lamivudine, and Tenofovir disoproxil. Efavirenz belongs to the class of non-nucleoside reverse transcriptase inhibitors. Lamivudine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme, which is essential for the reproduction of the virus.

Storage

Keep out of sight and reach of children.

Side effects of Vonaday Tablet

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Fatigue

Rest well; get enough sleep.
Eat a balanced diet and drink enough water.
Manage stress with yoga and meditation.
Limit alcohol and caffeine.
Physical activities like walking or jogging might help boost energy and make you feel less tired.

Dizziness

Here are the 7 steps to manage Dizziness caused by medication:

Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
When standing up, do so slowly and carefully to avoid sudden dizziness.
Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Indigestion

Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:

Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Muscle Pain

Here are the step-by-step strategies to manage the side effects of " Muscle Pain" caused by medication usage:

Report to Your Doctor: Inform your doctor about the muscle pain, as they may need to adjust your medication.
Stretch Regularly: Gentle stretching can help relieve muscle pain and stiffness.
Stay Hydrated: Adequate water intake supports muscle health by removing harmful substances and maintaining proper muscle function.
Warm or Cold Compresses: Apply cold or warm compresses to the affected area to reduce pain and inflammation.
Rest and Relaxation: Adequate rest helps alleviate muscle strain, while relaxation techniques like deep breathing and meditation can soothe muscle tightness, calm the mind, and promote relief from discomfort.
Gentle Exercise: Participate in low-impact activities, such as yoga or short walks, to improve flexibility, reduce muscle tension, and alleviate discomfort.
Consult a physician: If your symptoms don't improve or get worse, go to the doctor for help and guidance.

Enlarged Spleen

Eat a balanced diet rich in fruits, vegetables, whole grains, lean protein, and healthy fats.
Opt for lean protein sources like chicken, fish, and turkey.
Nourish your body with healthy fats from sources like avocados, olive oil, and fatty fish to support overall well-being.
Restrict your consumption of processed foods, sugary beverages, and refined carbs to minimize negative impacts on your health.
Adopt a mindful approach to alcohol consumption, opting for moderation to maintain a healthy balance.
Engage in moderate exercise like walking, swimming, or yoga.
Maintain a healthy weight to alleviate spleen pressure.
Refrain from participating in high-risk activities that involve physical collision or intense impact.
Ensure your safety while driving by consistently wearing a seatbelt to minimize injury risk.
Stay hydrated by drinking plenty of water.
Consult your doctor before making diet and lifestyle changes.

Drug Warnings

Let your doctor know if you are using a prescription, non-prescription drugs, and herbal products before starting VONADAY TABLET. Inform your doctor if you are allergic to VONADAY TABLET or its inactive components. Please inform your doctor if you have heart problems, liver (hepatitis B or C, cirrhosis) or kidney diseases, depression, pancreas (inflammation of the pancreas), alcohol addiction, fits, high cholesterol levels, and weak/broken bones (osteoporosis). You are advised to take proper precautions if you are infected with HIV infection to prevent the spread of infection to others through sexual contact or body fluids. VONADAY TABLET should be used with caution due to the increased risk of immune reconstitution syndrome, decreased bone mineral density, pancreatitis, and lactic acidosis. Pregnant women should consult their doctor before taking VONADAY TABLET. It is not recommended to breastfeed while using VONADAY TABLET since it excretes into the breast milk. VONADAY TABLET may cause dizziness/drowsiness, so do not drive or operate heavy machinery if you feel dizzy or drowsy.

Drug-Drug Interactions

EfavirenzBepridil

Critical

EfavirenzLomitapide

Critical

Drug-Drug Interactions

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EfavirenzBepridil

Critical

How does the drug interact with Vonaday Tablet:
Taking Bepridil with Vonaday Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Bepridil with Vonaday Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

EfavirenzLomitapide

Critical

How does the drug interact with Vonaday Tablet:
When Vonaday Tablet is taken with Lomitapide it can increase the risk or severity of liver damage.

How to manage the interaction:
Taking Vonaday Tablet with Lomitapide is not recommended as it results in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.

EfavirenzCisapride

Critical

How does the drug interact with Vonaday Tablet:
Taking Vonaday Tablet and Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Vonaday Tablet and Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

EfavirenzErgometrine

Critical

How does the drug interact with Vonaday Tablet:
When Vonaday Tablet is taken with Ergometrine, the level of Ergometrine in the body can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ergometrine with Vonaday Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, ringing of the ears, chest pain, palpitation, or irregular heartbeats contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

EfavirenzCarbamazepine

Critical

How does the drug interact with Vonaday Tablet:
Using carbamazepine together with Vonaday Tablet may reduce the effect of carbamazepine.

How to manage the interaction:
Taking Vonaday Tablet with Carbamazepine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.

EfavirenzThioridazine

Critical

How does the drug interact with Vonaday Tablet:
Taking Vonaday Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Vonaday Tablet with Thioridazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

EfavirenzDienogest

Critical

How does the drug interact with Vonaday Tablet:
When Vonaday Tablet is taken with Dienogest, it can lower the metabolism of Dienogest and increase the risk or severity of side effects.

How to manage the interaction:
Taking Vonaday Tablet with Dienogest can possibly result in an interaction, however, it can be taken when advised by a doctor. Do not stop using any medications without talking to a doctor.

EfavirenzRanolazine

Critical

How does the drug interact with Vonaday Tablet:
When Vonaday Tablet is taken with Ranolazine, it can lower the levels of Ranolazine.

How to manage the interaction:
Taking Ranolazine with Vonaday Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.

EfavirenzGrepafloxacin

Critical

How does the drug interact with Vonaday Tablet:
Taking Vonaday Tablet with Grepafloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Vonaday Tablet with Grepafloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

EfavirenzVoriconazole

Critical

How does the drug interact with Vonaday Tablet:
Coadministration of Voriconazole with Vonaday Tablet can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Voriconazole with Vonaday Tablet can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
Avoid sharing used needles, other injection or drug equipment.
Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis as they can make you prone to HIV infection.
Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
Try to reduce emotional and physical stress by spending time with family or do whatever makes you happy.

Side Effects of VONADAY TABLET

Nausea
Headache
Dizziness
Depression
Sleeping problems
Weakness
Tiredness
Cough
Rash
Unusual dreams
Concentration problems
Drowsiness (sleepiness)
Diarrhoea

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

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Author Details

Written By

Divya L

PharmaD

Reviewed By

Sureshvarma D

MPharma

Last Updated

Jul 8, 2025 | 9:39 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does VONADAY TABLET work?

VONADAY TABLET contains Efavirenz, Lamivudine, and Tenofovir disoproxil. It works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, VONADAY TABLET helps in treating HIV infection.

Does VONADAY TABLET cause bone problems?

VONADAY TABLET may cause bone problems, such as osteonecrosis (death of bone tissue due to loss of blood supply to the bone), especially in HIV patients taking combination antiretroviral therapy. If you experience any joint pains, stiffness (especially shoulder, knee or hip) or difficulty in movement, please consult a doctor immediately.

Is HIV infection contagious while using VONADAY TABLET?

HIV infection may still be transmitted to other persons while using VONADAY TABLET. VONADAY TABLET reduces the risk of transmission; however, HIV infection is still contagious. Therefore, discuss with a doctor for precautions to avoid transmission of HIV while being treated with VONADAY TABLET.

Does VONADAY TABLET cure HIV infection?

VONADAY TABLET does not cure HIV infection. VONADAY TABLET reduces the activity of HIV in the body and improves the functioning of the immune system.

Does VONADAY TABLET cause lactic acidosis?

VONADAY TABLET may cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are very obese and in people with liver diseases. However, if you experience stomach pain, vomiting or nausea while taking VONADAY TABLET, please consult a doctor immediately.

Drug-Drug Interactions Checker List

AMPHOTERICIN B
FOSCARNET
GANCICLOVIR
CIDOFOVIR
ORLISTAT
ADEFOVIR
OMBITASVIR
PARITAPREVIR
RITONAVIR
DASABUVIR
TACROLIMUS
AMIKACIN
GENTAMICIN
PENTAMIDINE
VANCOMYCIN
CARBAMAZEPINE

Special Advise

Regular kidney and liver function tests, bone mineral density tests are recommended while taking VONADAY TABLET.

Disease/Condition Glossary

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms, such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. HIV spreads through body fluids, such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs.