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Written By Divya L , PharmaD
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About VONADAY TABLET

VONADAY TABLET belongs to the class of ‘antiretrovirals,’ used to treat HIV infection. VONADAY TABLET helps in decreasing the chance of developing AIDS (acquired immunodeficiency syndrome). HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses.

VONADAY TABLET is a combination of three medicines: Efavirenz, Lamivudine, and Tenofovir disoproxil. Efavirenz is a non-nucleoside reverse transcriptase inhibitor. Lamivudine is a nucleoside reverse transcriptase inhibitor. Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme, which is essential for the reproduction of the virus. 

Your doctor will decide the dosage based on your medical condition. Sometimes, VONADAY TABLET may have common side effects like nausea, headache, dizziness, depression, sleeping problems, weakness, tiredness, cough, rash, unusual dreams, concentration problems, drowsiness (sleepiness), and diarrhoea. These side effects do not require medical attention and gradually resolve over time. However, if these side effects persist for a longer time, please seek medical advice.

Let your doctor know if you are using a prescription, non-prescription drugs, and herbal products before starting VONADAY TABLET. If you are known to be allergic to VONADAY TABLET or its inactive components, please inform your doctor. Please tell your doctor if you have any heart problems, liver or kidney diseases, alcohol addiction, fits, high cholesterol levels, and weak/broken bones. If you are pregnant, please consult your doctor before taking VONADAY TABLET. Do not breastfeed while taking VONADAY TABLET. VONADAY TABLET is recommended for children who weigh at least 77 pounds (35 kg).

Uses of VONADAY TABLET

HIV infection.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

VONADAY TABLET is used to treat HIV infection. It consists of three medicines, namely: Efavirenz, Lamivudine, and Tenofovir disoproxil. Efavirenz belongs to the class of non-nucleoside reverse transcriptase inhibitors. Lamivudine is a nucleoside reverse transcriptase inhibitor, whereas Tenofovir disoproxil is a nucleotide reverse transcriptase inhibitor. They work by inhibiting the reverse transcriptase enzyme, which is essential for the reproduction of the virus. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Let your doctor know if you are using a prescription, non-prescription drugs, and herbal products before starting VONADAY TABLET. Inform your doctor if you are allergic to VONADAY TABLET or its inactive components. Please inform your doctor if you have heart problems, liver (hepatitis B or C, cirrhosis) or kidney diseases, depression, pancreas (inflammation of the pancreas), alcohol addiction, fits, high cholesterol levels, and weak/broken bones (osteoporosis). You are advised to take proper precautions if you are infected with HIV infection to prevent the spread of infection to others through sexual contact or body fluids. VONADAY TABLET should be used with caution due to the increased risk of immune reconstitution syndrome, decreased bone mineral density, pancreatitis, and lactic acidosis. Pregnant women should consult their doctor before taking VONADAY TABLET. It is not recommended to breastfeed while using VONADAY TABLET since it excretes into the breast milk. VONADAY TABLET may cause dizziness/drowsiness, so do not drive or operate heavy machinery if you feel dizzy or drowsy.

Drug-Drug Interactions

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EfavirenzRilpivirine
Critical
EfavirenzBepridil
Critical

Drug-Drug Interactions

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EfavirenzRilpivirine
Critical
How does the drug interact with Vonaday Tablet:
Taking Rilpivirine with Vonaday Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Rilpivirine with Vonaday Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EfavirenzBepridil
Critical
How does the drug interact with Vonaday Tablet:
Taking Bepridil with Vonaday Tablet can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Bepridil with Vonaday Tablet can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vonaday Tablet:
Using ziprasidone together with Vonaday Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Vonaday Tablet with Ziprasidone is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vonaday Tablet:
Taking Vonaday Tablet with Thioridazine can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Vonaday Tablet with Thioridazine together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vonaday Tablet:
Taking Vonaday Tablet and Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Vonaday Tablet and Cisapride together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vonaday Tablet:
Using carbamazepine together with Vonaday Tablet may reduce the effect of carbamazepine.

How to manage the interaction:
Taking Vonaday Tablet with Carbamazepine can result in an interaction, it can be taken if your doctor has advised it. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.
EfavirenzErgometrine
Critical
How does the drug interact with Vonaday Tablet:
When Vonaday Tablet is taken with Ergometrine, the level of Ergometrine in the body can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ergometrine with Vonaday Tablet is not recommended as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, abdominal pain, diarrhea, headache, dizziness, ringing of the ears, chest pain, palpitation, or irregular heartbeats contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vonaday Tablet:
When Vonaday Tablet is taken with Ranolazine, it can lower the levels of Ranolazine.

How to manage the interaction:
Taking Ranolazine with Vonaday Tablet is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medication without consulting a doctor.
EfavirenzGrepafloxacin
Critical
How does the drug interact with Vonaday Tablet:
Taking Vonaday Tablet with Grepafloxacin can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Vonaday Tablet with Grepafloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Vonaday Tablet:
Coadministration of Voriconazole with Vonaday Tablet can alter the blood levels and effects of both medications.

How to manage the interaction:
Taking Voriconazole with Vonaday Tablet can be taken if a doctor has advised it. Contact a doctor if you experience vomiting, dizziness, difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Practise safe sex by using condoms; it helps in reducing contact with semen and vaginal fluids.
  • Never share personal items that can have body fluids or blood on them, such as razor blades or toothbrushes.
  • Avoid sharing used needles, other injection or drug equipment.
  • Get tested for other sexually transmitted infections, such as gonorrhoea or syphilis as they can make you prone to HIV infection.
  • Eat a healthy and balanced diet. Eat vitamin and nutrient-rich food such as dark-green, yellow, orange, and red vegetables and fruits as it helps to boost your immune system. Opt for lean protein and whole grains.
  • Avoid eating raw meat and eggs. Consume properly boiled and cooked meat, poultry or seafood.
  • Eat bland and low-fat foods and avoid spicy or oily foods if you experience nausea or vomiting.
  • Try to reduce emotional and physical stress by spending time with family or do whatever makes you happy.

Habit Forming

No

Therapeutic Class

ANTIRETROVIRAL AGENTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

VONADAY TABLET contains Efavirenz, Lamivudine, and Tenofovir disoproxil. It works by interfering with the functioning of nucleotide and nucleoside reverse transcriptase enzymes necessary for the reproduction of the virus. Together, VONADAY TABLET helps in treating HIV infection.

VONADAY TABLET may cause bone problems, such as osteonecrosis (death of bone tissue due to loss of blood supply to the bone), especially in HIV patients taking combination antiretroviral therapy. If you experience any joint pains, stiffness (especially shoulder, knee or hip) or difficulty in movement, please consult a doctor immediately.

HIV infection may still be transmitted to other persons while using VONADAY TABLET. VONADAY TABLET reduces the risk of transmission; however, HIV infection is still contagious. Therefore, discuss with a doctor for precautions to avoid transmission of HIV while being treated with VONADAY TABLET.

VONADAY TABLET does not cure HIV infection. VONADAY TABLET reduces the activity of HIV in the body and improves the functioning of the immune system.

VONADAY TABLET may cause lactic acidosis (excess of lactic acid in the blood), a rare but severe side effect, especially in women who are very obese and in people with liver diseases. However, if you experience stomach pain, vomiting or nausea while taking VONADAY TABLET, please consult a doctor immediately.

Drug-Drug Interactions Checker List

  • AMPHOTERICIN B
  • FOSCARNET
  • GANCICLOVIR
  • CIDOFOVIR
  • ORLISTAT
  • ADEFOVIR
  • OMBITASVIR
  • PARITAPREVIR
  • RITONAVIR
  • DASABUVIR
  • TACROLIMUS
  • AMIKACIN
  • GENTAMICIN
  • PENTAMIDINE
  • VANCOMYCIN
  • CARBAMAZEPINE

Special Advise

Regular kidney and liver function tests, bone mineral density tests are recommended while taking VONADAY TABLET.

Disease/Condition Glossary

HIV infection: HIV (Human Immunodeficiency Virus) is a virus that attacks the immune system and destroys the white blood cells that help in fighting infection, making the individual susceptible to other infections or illnesses. People with HIV experience flu-like symptoms, such as fever, chills, rash, night sweats, muscle aches, tiredness, and sore throat. These symptoms usually last for days to several weeks. HIV spreads through body fluids, such as semen, vaginal fluid, and blood. If left untreated, this condition can lead to AIDS (Acquired Immunodeficiency Syndrome). It is a life-long condition, and there is no definite cure for it. However, it can be controlled by treating with antiretroviral drugs.

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