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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Synonym

METFORMIN HYDROCHLORIDE+VOGLIBOSE

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About VOSAFE M 0.2MG TABLET 10'S

VOSAFE M 0.2MG TABLET 10'S belongs to the class of anti-diabetic drugs. It is used in the treatment of type 2 diabetes mellitus. Diabetes mellitus is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance) or the pancreas (an organ behind the stomach) produces little or no insulin at all.

VOSAFE M 0.2MG TABLET 10'S is composed of two medicines, namely Voglibose and Metformin. Voglibose belongs to the class of alpha-glucosidase inhibitors. It acts by inhibiting the intestinal enzymes, which break complex sugars into simple sugars such as glucose. This process prevents the rise of blood glucose levels. Metformin belongs to the class of biguanides and exhibits non-pancreatic effect to reduce serum glucose levels without increasing insulin secretion. It is also known as an insulin sensitizer as it increases the effects of insulin. Metformin is considered to be a unique anti-diabetic drug since it does not cause hypoglycemia (lowered blood sugar levels).

Take VOSAFE M 0.2MG TABLET 10'S with food at regular intervals as prescribed by your doctor. Your doctor will decide the dosage form, and this may change timely depending on your blood sugar levels. The common side effects of VOSAFE M 0.2MG TABLET 10'S include nausea, vomiting, changes in taste, diarrhoea, dizziness, stomach pain, shortness of breath, skin rash, bloating, and flatulence (intestinal wind/gas). Although not everyone experiences these side effects, if they occur, seek medical attention. Lactic acidosis, is a rare, but serious metabolic complication of excess lactic acid in the blood that is caused by metformin accumulation is reported. The risk of lactic acidosis is high in people with kidney, liver, and heart diseases.

Before starting VOSAFE M 0.2MG TABLET 10'S, let your doctor know if you have any medical history of anaemia (low hemoglobin levels), seizures (fits), heart, kidney, and liver diseases. VOSAFE M 0.2MG TABLET 10'S does not cause hypoglycemia (low blood sugar levels). However, when used with other diabetic drugs like insulin or sulfonylureas, it can lead to hypoglycemia. Also, speak to your doctor if you are on restricted food or fluid intake since VOSAFE M 0.2MG TABLET 10'S causes dehydration, low blood sugar, and kidney damage. Do not take VOSAFE M 0.2MG TABLET 10'S if you have gastrointestinal diseases like ulcerative colitis or Crohn’s disease. Do not take or stop VOSAFE M 0.2MG TABLET 10'S, if the doctor did not advise you to do so.

Uses of VOSAFE M 0.2MG TABLET 10'S

Type 2 Diabetes mellitus.

Directions for Use

Tablet: Swallow it as a whole with water; do not crush, break or chew it.Take VOSAFE M 0.2MG TABLET 10'S preferably with a meal, since it lowers the blood sugar levels and causes gastrointestinal side effects. Your doctor may start the course with a low dose and gradually maintain an effective dose to achieve the required blood glucose control.

Medicinal Benefits

VOSAFE M 0.2MG TABLET 10'S is used to treat type 2 diabetes mellitus. It is a combination of Voglibose and Metformin. Voglibose belongs to the class of alpha-glucosidase inhibitors. It delays glucose absorption by inhibiting the intestinal enzymes, which break complex sugars into simple sugars such as glucose. This process prevents the rise of blood glucose levels immediately after meals. Metformin belongs to the class of biguanides. It shows the non-pancreatic effect to reduce serum glucose levels without increasing insulin secretion. It is also known as an insulin sensitizer as it increases the effects of insulin. It is considered to be a unique anti-diabetic drug since it does not lower blood sugar levels. Metformin does not cause weight gain in most cases.

Storage

Store in a cool and dry place away from sunlight

Side Effects of VOSAFE M 0.2MG TABLET 10'S

Common side effects:

  • Nausea
  • Vomiting
  • Changes in taste
  • Diarrhoea
  • Dizziness
  • Stomach pain
  • Shortness of breath
  • Skin rash
  • Bloating
  • Flatulence (intestinal wind/gas)

Rare side effects:

  • Lactic acidosis

Drug Warnings

VOSAFE M 0.2MG TABLET 10'S may increase the risk of cardiovascular diseases and hypoglycemic conditions in renal and liver disease patients. It can cause pneumatosis intestinalis (gas-filled cysts on the bowel wall) when used along with other alpha-gastrointestinal drugs. It is advised to monitor the gastrointestinal side effects thoroughly to rule out the possibility of pneumatosis intestinalis. VOSAFE M 0.2MG TABLET 10'S has an increased risk of lactic acidosis (a rare, but serious metabolic complication of excess lactic acid in the blood that is caused by metformin accumulation). The risk of lactic acidosis is high in older people with kidney, liver, and heart diseases. Hence, brief your medical history and take advice from your doctor before starting VOSAFE M 0.2MG TABLET 10'S. Avoid consuming excessive alcohol as it can potentiate lactic acidosis.

Drug-Drug Interactions

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MetforminIopentol
Critical
MetforminIotroxic acid
Critical

Drug-Drug Interactions

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MetforminIopentol
Critical
How does the drug interact with Vosafe M 0.2mg Tablet:
Co-administration of Iopentol with Vosafe M 0.2mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vosafe M 0.2mg Tablet with Iopentol is not recommended, please consult your doctor before taking it.
MetforminIotroxic acid
Critical
How does the drug interact with Vosafe M 0.2mg Tablet:
Co-administration of Iotroxic acid with Vosafe M 0.2mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vosafe M 0.2mg Tablet with Iotroxic acid is not recommended, please consult your doctor before taking it.
MetforminIohexol
Critical
How does the drug interact with Vosafe M 0.2mg Tablet:
Co-administration of Iohexol with Vosafe M 0.2mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vosafe M 0.2mg Tablet with Iohexol is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIobenzamic acid
Critical
How does the drug interact with Vosafe M 0.2mg Tablet:
Co-administration of Vosafe M 0.2mg Tablet and Iobenzamic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Vosafe M 0.2mg Tablet with Iobenzamic acid is generally avoided as it can result in an interaction, please consult your doctor before taking it.
MetforminIodamide
Critical
How does the drug interact with Vosafe M 0.2mg Tablet:
Co-administration of Vosafe M 0.2mg Tablet with Iodamide may increase the risk of kidney problems.

How to manage the interaction:
Taking Vosafe M 0.2mg Tablet with Iodamide is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIoversol
Critical
How does the drug interact with Vosafe M 0.2mg Tablet:
Co-administration of Ioversol with Vosafe M 0.2mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vosafe M 0.2mg Tablet with Ioversol is not recommended, please consult your doctor before taking it.
MetforminIopanoic acid
Critical
How does the drug interact with Vosafe M 0.2mg Tablet:
Co-administration of Iopanoic acid with Vosafe M 0.2mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vosafe M 0.2mg Tablet with Iopanoic acid is not recommended, please consult your doctor before taking it.
MetforminIodixanol
Critical
How does the drug interact with Vosafe M 0.2mg Tablet:
Co-administration of Iodixanol with Vosafe M 0.2mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vosafe M 0.2mg Tablet with Iodixanol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.
MetforminIocarmic acid
Critical
How does the drug interact with Vosafe M 0.2mg Tablet:
Co-administration of Vosafe M 0.2mg Tablet and Iocarmic acid can increase the risk of lactic acidosis (when the body produces too much lactic acid).

How to manage the interaction:
Taking Vosafe M 0.2mg Tablet with Iocarmic acid is generally avoided as it can result in an interaction. please consult your doctor before taking it.
MetforminIomeprol
Critical
How does the drug interact with Vosafe M 0.2mg Tablet:
Co-administration of Iomeprol with Vosafe M 0.2mg Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Vosafe M 0.2mg Tablet with Iomeprol is not recommended, please consult a doctor before taking it. Do not discontinue the medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a fiber-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on how to notice and manage the early symptoms of high/low blood sugar levels.
  • Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include cutting down on sugars and fatty foods, and avoiding carbonated drinks and foods that cause gas.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • SELEGILINE
  • PREDNISOLONE
  • PHENYLBUTAZONE
  • METOLAZONE
  • HYDROCHLOROTHIAZIDE
  • METOPROLOL
  • PROPRANOLOL
  • ISOCARBOXAZID
  • PHENELZINE
  • CHLOROTHIAZIDE

Special Advise

Regular blood tests are recommended while taking VOSAFE M 0.2MG TABLET 10'S to monitor blood sugar levels.

Disease/Condition Glossary

Diabetes Mellitus type 2 is a condition in which either the body stops producing enough insulin (the hormone which helps to decrease sugar levels in the blood) or there is resistance to the action of insulin. As a result, excessive insulin is produced but it fails to act on the organs of the body. Symptoms of type 2 diabetes include feeling exhausted all time, feeling thirsty, having blurry vision, and the urge to urinate (pee) more often. Complications of type 2 diabetes include skin infection, eye problems (retinopathy), nerve damage (neuropathy), delayed wound healing, diabetic foot (foot ulcer), kidney disease (nephropathy), high blood pressure, and even stroke. Both low and high blood sugar levels can be dangerous and should be treated as soon as possible. Your H1bA1C below 5.7% is normal, 5.7-6.4% confirms the prediabetes stage, and 6.5% or greater states diabetes condition.

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