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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Composition :

PERTUZUMAB-420MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

About Womab 420 mg Injection 14 ml

Womab 420 mg Injection 14 ml is an anti-cancer medicine used in the treatment of Breast cancer. Cancer is a disease where the cells grow abnormally and divide uncontrollably. The abnormal growth of cancer (malignant) cells in the breast is known as breast cancer. Womab 420 mg Injection 14 ml is combined with trastuzumab and docetaxel for treating patients with HER2-positive metastatic breast cancer who have not received any chemotherapy for metastatic breast cancer. This medicine is also used in combination with docetaxel and trastuzumab as a neoadjuvant treatment of breast cancer in patients with HER2-positive (human epidermal growth factor receptor 2) or as part of a complete treatment regimen for early breast cancer.

Womab 420 mg Injection 14 ml contains Pertuzumab as a active ingredient which belongs to the class of monoclonal antibodies. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Womab 420 mg Injection 14 ml may cause certain side effects such as fatigue, nausea, headache, vomiting, dizziness, hair loss, constipation, dry skin, myalgia, upper respiratory tract infections, diarrhea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer Womab 420 mg Injection 14 ml. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

Womab 420 mg Injection 14 ml should be avoided if you are allergic to it or any other components of this medicine. Womab 420 mg Injection 14 ml may cause left ventricular dysfunction, anaphylaxis, or hypersensitivity reactions during the treatment. Hence, careful observation should be performed for any reactions in the patient. If any changes or hypersensitivity reactions occur, treatment should be discontinued. Inform your doctor if you have any cardiovascular conditions or liver/kidney disease, as it can cause adverse effects. Womab 420 mg Injection 14 ml is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand. The use of Womab 420 mg Injection 14 ml along with the doxorubicin-containing regimen is not established. Hence, if you are on such treatment, inform your doctor before starting the treatment. Womab 420 mg Injection 14 ml is not recommended for use in children as the safety and efficacy are not established.

Uses of Womab 420 mg Injection 14 ml

Breast Cancer.

Directions for Use

A trained oncologist will administer Womab 420 mg Injection 14 ml. Hence, do not self-administer.

Medicinal Benefits

Womab 420 mg Injection 14 ml contains Pertuzumab, which belongs to the class of monoclonal antibodies. It works by inhibiting the excess production of a human epidermal growth factor receptor 2 (HER2) protein in the mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis. Womab 420 mg Injection 14 ml is used in combination with trastuzumab and docetaxel for the treatment of breast cancer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Womab 420 mg Injection 14 ml should be avoided if you are allergic to it or any other components of this medicine. Womab 420 mg Injection 14 ml may cause left ventricular dysfunction, anaphylaxis, or hypersensitivity reactions during the treatment. Hence, careful observation should be performed for any reactions in the patient. If any changes or hypersensitivity reactions occur, treatment should be discontinued. Inform your doctor if you have any cardiovascular conditions or liver/kidney disease, as it can cause adverse effects. Womab 420 mg Injection 14 ml is known to cause embryo-fetal toxicity. Hence, if you are pregnant or breastfeeding, inform your doctor beforehand. The use of Womab 420 mg Injection 14 ml along with the doxorubicin-containing regimen is not established. Hence, if you are on such treatment, inform your doctor before starting the treatment. Womab 420 mg Injection 14 ml is not recommended for use in children as the safety and efficacy are not established.

Diet & Lifestyle Advise

  • Meditation and yoga have been proven very effective in helping cancer patients maintain a healthy attitude and body.
  • Eat more lean meats, healthy fats, fruits, vegetables, and whole-grain foods to give you more energy. 
  • Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
  • Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Womab 420 mg Injection 14 ml Substitute

Substitutes safety advice
  • Sigrima 420 mg Injection 14 ml

    by Others

    5713.93per tablet

FAQs

Womab 420 mg Injection 14 ml contains Pertuzumab, which works by inhibiting the excess production of a protein called human epidermal growth factor receptor 2 (HER2) in mammalian cells. This causes inhibition of the cancer cell growth and, finally, initiation of apoptosis.

Inform your doctor whether you have received any other breast cancer treatment containing doxorubicin in your medication list. Womab 420 mg Injection 14 ml may cause left ventricular dysfunction, anaphylaxis, hypersensitivity reactions, and embryo-fetal toxicity during the treatment. Hence, inform your oncologist if you have any cardiovascular conditions, liver/kidney disease, are pregnant, are planning to become pregnant, or are breastfeeding before receiving Womab 420 mg Injection 14 ml.

Drug-Drug Interactions Checker List

  • ANASTROZOLE
  • CARMUSTINE
  • DAUNORUBICIN
  • ABCIXIMAB
  • BLEOMYCIN
  • BUPIVACAINE

Special Advise

  • Avoid intercourse while on treatment with Womab 420 mg Injection 14 ml.
  • Regular, complete blood count monitoring is advised.  Also, monitoring of liver function is important while receiving Womab 420 mg Injection 14 ml.
  • Womab 420 mg Injection 14 ml should not be administered for more than six cycles for patients with early-stage breast cancer.
  • All patients should be tested for HER2 test before starting the treatment regimen.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer with abnormal growth in the cells of the breast. There are different kinds of breast cancer, such as cancer occurring in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, a lump or swelling under the arm, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin. 

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