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Reviewed By Sureshvarma D , MPharma
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Composition :

SAFINAMIDE-100MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Xafinact 100 Tablet

Xafinact 100 Tablet belongs to a class of drugs called antiparkinson agents, which are used in combination with other drugs for the treatment of the signs and symptoms of Parkinson's disease. Parkinson’s disease is a disorder of the central nervous system that affects movement and locomotion. It causes stiffness, shaking, and difficulty in walking, coordination and balance. 

Xafinact 100 Tablet contains 'safinamide', belonging to the group of medications called monoamine oxidase type B (MAO-B) inhibitors. It works by increasing the amount of dopamine (a natural substance that is needed to control movement) in the brain.

Xafinact 100 Tablet may cause common side effects like cough, depression, indigestion, flu-like symptoms, insomnia (difficulty sleeping), joint pain, and peripheral oedema. Most of these side effects of  Xafinact 100 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Xafinact 100 Tablet or any other medicines, please tell your doctor. Please inform your doctor if you are using any medications other than Xafinact 100 Tablet . If you are pregnant or breastfeeding, it is advised to inform your doctor. Xafinact 100 Tablet is not recommended in albinism, retinal degeneration, uveitis, inherited retinopathy or severe progressive diabetic retinopathy. Xafinact 100 Tablet should be used with caution in patients like schizophrenia (a mental illness that causes disturbed thinking, loss of interest in life, and strong or unusual emotions), bipolar disorder (mood that changes from depressed to abnormally excited), or psychosis; or if you have high or low blood pressure; dyskinesia (abnormal movements); or sleep problems. Xafinact 100 Tablet may cause serotonin syndrome when used with MAO inhibitors, antidepressants, or opioid drugs.

Uses of Xafinact 100 Tablet

Parkinson's disease

Directions for Use

Swallow Xafinact 100 Tablet as a whole with water. Do not chew, crush or break it.

Medicinal Benefits

Xafinact 100 Tablet belongs to a class of drugs called antiparkinson agents, which are used in combination with other drugs for the treatment of the signs and symptoms of Parkinson's disease. It works by increasing the amount of dopamine (a natural substance needed to control movement) in the brain. Thereby improving the symptoms of Parkinson’s disease.

Storage

keep Xafinact 100 Tablet out of sight and reach of children.

Drug Warnings

If you are known to be allergic to Xafinact 100 Tablet or any other medicines, please tell your doctor. Please inform your doctor if you are using any medications other than Xafinact 100 Tablet . If you are pregnant or breastfeeding, it is advised to inform your doctor. Xafinact 100 Tablet is not recommended in albinism, retinal degeneration, uveitis, inherited retinopathy or severe progressive diabetic retinopathy. Xafinact 100 Tablet should be used with caution in patients like schizophrenia (a mental illness that causes disturbed thinking, loss of interest in life, and strong or unusual emotions), bipolar disorder (mood that changes from depressed to abnormally excited), or psychosis; or if you have high or low blood pressure; dyskinesia (abnormal movements); or sleep problems. Xafinact 100 Tablet should be used caution with liver diseases. Xafinact 100 Tablet may cause serotonin syndrome when used with MAO inhibitors, antidepressants or opioid drugs. A combination of MAOIs and dextromethorphan has been reported to cause episodes of psychosis or abnormal behaviour.

Diet & Lifestyle Advise

  • A balanced diet is essential to show improvement in Parkinson's disease, including grains and leafy foods, as this food is rich in vitamins, fibres, and minerals. With this food, one should also include dairy items, protein-rich nourishments, for example, meat and beans, and solid fats found in nuts, olive oil, fish, and eggs in their diet. However, limit the consumption of sugar.
  • Avoid intake of high-protein foods like soy protein, fish, eggs, chicken, beef, and pork. Eat more whole-grain foods such as whole wheat bread, oatmeal, brown rice or pasta.
  • Eat more fibre-rich foods to ease constipation.
  • Drink plenty of water to avoid headaches due to dehydration.
  • Avoid the consumption of alcohol as it may increase drowsiness.

Side Effects of Xafinact 100 Tablet

  • Cough
  • Depression
  • Indigestion
  • Flu-like symptoms
  • Insomnia (difficulty in sleeping)
  • Joint pain
  • Peripheral oedema

Habit Forming

No

Therapeutic Class

ANTIPARKINSON AGENTS

FAQs

Xafinact 100 Tablet works by increasing the amount of dopamine (a natural substance needed to control movement) in the brain. Thereby improving the symptoms of Parkinson’s disease.

Do not double the dosage to compensate for a missed one. One can skip the missed portion and take the next dosage at the standard time of the following day.

Yes, Xafinact 100 Tablet is not recommended in albinism (an inherited condition that causes a lack of colour in the skin, hair and eyes), retinal degeneration, uveitis (inflammation of the middle layer of the eye (uvea)), inherited retinopathy or severe progressive diabetic retinopathy.

Do not stop Xafinact 100 Tablet suddenly; it may cause side effects like confusion, stiff muscles and a high fever. So please consult your doctor before stopping the medicine.

Drug-Drug Interactions Checker List

  • DICLOFENAC
  • TRAMADOL
  • FLUOXETINE
  • BUPROPION
  • AMITRIPTYLINE
  • BALOFLOXACIN
  • CIPROFLOXACIN
  • CARBAMAZEPINE
  • ROSUVASTATIN
  • PITAVASTATIN
  • PRAVASTATIN
  • METHOTREXATE
  • GLYBURIDE
  • MEPERIDINE
  • METHADONE
  • PROPOXYPHENE
  • ISOCARBOXAZID
  • LINEZOLID
  • METHYLENE BLUE
  • MOCLOBEMIDE
  • PHENELZINE
  • PROCARBAZINE
  • RASAGILINE
  • SELEGILINE
  • TRANYLCYPROMINE
  • DEXTROMETHORPHAN
  • TOPOTECAN

Special Advise

  • Talk to your doctor if you develop hallucinations or other changes in your behaviour.

Disease/Condition Glossary

Parkinson’s disease: It is a disorder of the central nervous system that affects movement due to damage of nerve cells in the brain which reduces the levels of dopamine and leads to symptoms such as stiffness, tremor in one hand, shaking, difficulty in walking, coordination and balance. This condition can last for many years or life-long. Treatment with medicines and physiotherapy may help control the symptoms and provide a quality life for as long as possible.

Have a query?

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Alcohol

Caution

Xafinact 100 Tablet may cause excessive drowsiness with alcohol, decreasing alertness and affecting your vision.

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Pregnancy

Unsafe

Xafinact 100 Tablet may be unsafe to use during pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Xafinact 100 Tablet . Please consult your doctor before taking Xafinact 100 Tablet .

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Breast Feeding

Unsafe

Xafinact 100 Tablet may be unsafe to use in breastfeeding mothers. Your doctor will weigh the benefits and potential risks before prescribing Xafinact 100 Tablet . Please consult your doctor before taking Xafinact 100 Tablet .

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Driving

Caution

Xafinact 100 Tablet may decrease alertness, affect your vision or make you sleepy and dizzy. Do not drive if these symptoms occur.

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Liver

Caution

Xafinact 100 Tablet should be used with caution in patients with liver disease. A dose adjustment of Xafinact 100 Tablet may be needed. So please consult your doctor before taking Xafinact 100 Tablet .

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Kidney

Caution

Xafinact 100 Tablet should be used with caution in patients with kidney disease. A dose adjustment of Xafinact 100 Tablet may be needed. So please consult your doctor before taking Xafinact 100 Tablet .

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Children

Unsafe

Xafinact 100 Tablet is not recommended for use in children under 12 years.

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