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Xafinact 50 Tablet 10's

Xafinact 50 Tablet 10's

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Prescription drug
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Composition

SAFINAMIDE-50MG

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Xafinact 50 Tablet 10's

Xafinact 50 Tablet 10's belongs to a class of drugs called antiparkinson agents, which are used in combination with other drugs for the treatment of the signs and symptoms of Parkinson's disease. Parkinson’s disease is a disorder of the central nervous system that affects movement and locomotion. It causes stiffness, shaking, and difficulty in walking, coordination and balance. 

Xafinact 50 Tablet 10's contains 'safinamide', belonging to the group of medications called monoamine oxidase type B (MAO-B) inhibitors. It works by increasing the amount of dopamine (a natural substance that is needed to control movement) in the brain.

Xafinact 50 Tablet 10's may cause common side effects like cough, depression, indigestion, flu-like symptoms, insomnia (difficulty sleeping), joint pain, and peripheral oedema. Most of these side effects of  Xafinact 50 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Xafinact 50 Tablet 10's or any other medicines, please tell your doctor. Please inform your doctor if you are using any medications other than Xafinact 50 Tablet 10's. If you are pregnant or breastfeeding, it is advised to inform your doctor. Xafinact 50 Tablet 10's is not recommended in albinism, retinal degeneration, uveitis, inherited retinopathy or severe progressive diabetic retinopathy. Xafinact 50 Tablet 10's should be used with caution in patients like schizophrenia (a mental illness that causes disturbed thinking, loss of interest in life, and strong or unusual emotions), bipolar disorder (mood that changes from depressed to abnormally excited), or psychosis; or if you have high or low blood pressure; dyskinesia (abnormal movements); or sleep problems. Xafinact 50 Tablet 10's may cause serotonin syndrome when used with MAO inhibitors, antidepressants, or opioid drugs.

Uses of Xafinact 50 Tablet 10's

Parkinson's disease

Medicinal Benefits

Xafinact 50 Tablet 10's belongs to a class of drugs called antiparkinson agents, which are used in combination with other drugs for the treatment of the signs and symptoms of Parkinson's disease. It works by increasing the amount of dopamine (a natural substance needed to control movement) in the brain. Thereby improving the symptoms of Parkinson’s disease.

Directions for Use

Swallow Xafinact 50 Tablet 10's as a whole with water. Do not chew, crush or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Xafinact 50 Tablet 10's

  • Cough
  • Depression
  • Indigestion
  • Flu-like symptoms
  • Insomnia (difficulty in sleeping)
  • Joint pain
  • Peripheral oedema

Drug Warnings

If you are known to be allergic to Xafinact 50 Tablet 10's or any other medicines, please tell your doctor. Please inform your doctor if you are using any medications other than Xafinact 50 Tablet 10's. If you are pregnant or breastfeeding, it is advised to inform your doctor. Xafinact 50 Tablet 10's is not recommended in albinism, retinal degeneration, uveitis, inherited retinopathy or severe progressive diabetic retinopathy. Xafinact 50 Tablet 10's should be used with caution in patients like schizophrenia (a mental illness that causes disturbed thinking, loss of interest in life, and strong or unusual emotions), bipolar disorder (mood that changes from depressed to abnormally excited), or psychosis; or if you have high or low blood pressure; dyskinesia (abnormal movements); or sleep problems. Xafinact 50 Tablet 10's should be used caution with liver diseases. Xafinact 50 Tablet 10's may cause serotonin syndrome when used with MAO inhibitors, antidepressants or opioid drugs. A combination of MAOIs and dextromethorphan has been reported to cause episodes of psychosis or abnormal behaviour.

Drug Interactions

Drug-Drug Interaction: Xafinact 50 Tablet 10's may interact with other medicines like pain killers (diclofenac, tramadol), antidepressant medications (fluoxetine, bupropion, amitryptiline), antibiotics (balofloxacin, ciprofloxacin), anti-epileptics (carbamazepine), statins (rosuvastatin, pitavastatin, pravastatin), anti-cancer (methotrexate, topotecan), antidiabetic (glyburide), antitussive (dextromethorphan), opioid-medications (meperidine, methadone, propoxyphene), MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine),

Drug-Food Interaction: Xafinact 50 Tablet 10's may interact with foods that are high in tyramine, such as aged cheeses, fava beans, soy sauce, herring, pickled or processed meats, fish, and meats that are aged, dried, smoked, or fermented. Eating tyramine while taking this drug can raise your blood pressure which could cause life-threatening side effects. It may also interact with alcohol and St. John's wort.

Drug-Disease Interaction: The use of Xafinact 50 Tablet 10's is strictly restricted if a patient is already dealing with liver diseases, albinism, retinal degeneration, uveitis, inherited retinopathy or severe progressive diabetic retinopathy.

Drug-Drug Interactions Checker List

  • DICLOFENAC
  • TRAMADOL
  • FLUOXETINE
  • BUPROPION
  • AMITRIPTYLINE
  • BALOFLOXACIN
  • CIPROFLOXACIN
  • CARBAMAZEPINE
  • ROSUVASTATIN
  • PITAVASTATIN
  • PRAVASTATIN
  • METHOTREXATE
  • GLYBURIDE
  • MEPERIDINE
  • METHADONE
  • PROPOXYPHENE
  • ISOCARBOXAZID
  • LINEZOLID
  • METHYLENE BLUE
  • MOCLOBEMIDE
  • PHENELZINE
  • PROCARBAZINE
  • RASAGILINE
  • SELEGILINE
  • TRANYLCYPROMINE
  • DEXTROMETHORPHAN
  • TOPOTECAN

Habit Forming

No

Diet & Lifestyle Advise

  • A balanced diet is essential to show improvement in Parkinson's disease, including grains and leafy foods, as this food is rich in vitamins, fibres, and minerals. With this food, one should also include dairy items, protein-rich nourishments, for example, meat and beans, and solid fats found in nuts, olive oil, fish, and eggs in their diet. However, limit the consumption of sugar.
  • Avoid intake of high-protein foods like soy protein, fish, eggs, chicken, beef, and pork. Eat more whole-grain foods such as whole wheat bread, oatmeal, brown rice or pasta.
  • Eat more fibre-rich foods to ease constipation.
  • Drink plenty of water to avoid headaches due to dehydration.
  • Avoid the consumption of alcohol as it may increase drowsiness.

Special Advise

  • Talk to your doctor if you develop hallucinations or other changes in your behaviour.

Disease/Condition Glossary

Parkinson’s disease: It is a disorder of the central nervous system that affects movement due to damage of nerve cells in the brain which reduces the levels of dopamine and leads to symptoms such as stiffness, tremor in one hand, shaking, difficulty in walking, coordination and balance. This condition can last for many years or life-long. Treatment with medicines and physiotherapy may help control the symptoms and provide a quality life for as long as possible.

Country of origin

India

Manufacturer/Marketer address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Other Info - XAF0005

FAQs

Xafinact 50 Tablet 10's works by increasing the amount of dopamine (a natural substance needed to control movement) in the brain. Thereby improving the symptoms of Parkinson’s disease.
Do not double the dosage to compensate for a missed one. One can skip the missed portion and take the next dosage at the standard time of the following day.
Yes, Xafinact 50 Tablet 10's is not recommended in albinism (an inherited condition that causes a lack of colour in the skin, hair and eyes), retinal degeneration, uveitis (inflammation of the middle layer of the eye (uvea)), inherited retinopathy or severe progressive diabetic retinopathy.
Do not stop Xafinact 50 Tablet 10's suddenly; it may cause side effects like confusion, stiff muscles and a high fever. So please consult your doctor before stopping the medicine.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Caution

Xafinact 50 Tablet 10's may cause excessive drowsiness with alcohol, decreasing alertness and affecting your vision.

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Pregnancy

Unsafe

Xafinact 50 Tablet 10's may be unsafe to use during pregnancy. Your doctor will weigh the benefits and potential risks before prescribing Xafinact 50 Tablet 10's. Please consult your doctor before taking Xafinact 50 Tablet 10's.

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Breast Feeding

Unsafe

Xafinact 50 Tablet 10's may be unsafe to use in breastfeeding mothers. Your doctor will weigh the benefits and potential risks before prescribing Xafinact 50 Tablet 10's. Please consult your doctor before taking Xafinact 50 Tablet 10's.

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Driving

Caution

Xafinact 50 Tablet 10's may decrease alertness, affect your vision or make you sleepy and dizzy. Do not drive if these symptoms occur.

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Liver

Caution

Xafinact 50 Tablet 10's should be used with caution in patients with liver disease. A dose adjustment of Xafinact 50 Tablet 10's may be needed. So please consult your doctor before taking Xafinact 50 Tablet 10's.

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Kidney

Caution

Xafinact 50 Tablet 10's should be used with caution in patients with kidney disease. A dose adjustment of Xafinact 50 Tablet 10's may be needed. So please consult your doctor before taking Xafinact 50 Tablet 10's.

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Children

Unsafe

Xafinact 50 Tablet 10's is not recommended for use in children under 12 years.

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