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  1. Home
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  3. XALIBO 50MG INJECTION

XALIBO 50MG INJECTION, Pack of 1 INJECTION
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Whats That

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Composition :

DECITABINE-50MG

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About XALIBO 50MG INJECTION

XALIBO 50MG INJECTION belongs to the group of medicines called hypomethylation agents used to treat myelodysplastic syndrome. A myelodysplastic syndrome is a group of malignancies known as myelodysplastic syndromes that occur when immature blood cells in the bone marrow do not mature or turn into healthy blood cells.

XALIBO 50MG INJECTION contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow.

Decitabine should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer chemotherapeutic agents. Decitabine should usually be given for at least four cycles but may be continued if your doctor decides you will benefit from additional treatment. The most common adverse reactions of XALIBO 50MG INJECTION are injection site reactions, excessive tiredness, headache, dizziness, confusion, fast heartbeat, difficulty falling asleep or staying asleep, weakness, shortness of breath, nausea, constipation, diarrhoea, vomiting, heartburn, chest discomfort and swelling of the hands, feet, ankles, lower legs, or stomach. Talk with your doctor if you experience any of these side effects persistently.

Decitabine may harm your fetus. Avoid taking XALIBO 50MG INJECTION if you are pregnant or breastfeeding. You or your partner should not become pregnant while you are using decitabine. It would be best if you used birth control to prevent pregnancy in yourself or your partner during your treatment with decitabine and for two months afterwards. Call your doctor if you or your partner becomes pregnant while using decitabine. If you are breastfeeding. Do not breastfeed while you take this drug and for two weeks after your last dose. XALIBO 50MG INJECTION may cause dizziness, sleepiness, tiredness, and blurred vision, so drive only if alert. XALIBO 50MG INJECTION is not recommended for children below 18 years as safety and effectiveness have not been established. Inform your doctor about your health condition and medications before taking XALIBO 50MG INJECTION to rule out interactions.

Uses of XALIBO 50MG INJECTION

Myelodysplastic syndrome

Directions for Use

XALIBO 50MG INJECTION should be administered to patients only in a hospital setting under the supervision of a physician qualified by training and experience to administer cancer chemotherapeutic agents; do not self-administer.

Medicinal Benefits

XALIBO 50MG INJECTION belongs to the group of medicines called hypomethylation agents used to treat myelodysplastic syndrome. XALIBO 50MG INJECTION contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and kills abnormal cells in the bone marrow. On the other hand, it can treat blood cancer, known as acute myeloid leukemia (AML).

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Before taking the XALIBO 50MG INJECTION, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Before and during your therapy, your doctor will prescribe laboratory testing on a regular basis. You may have a higher risk of infection. Hands must be washed frequently. Avoid contact with those who have illnesses, colds, or the flu. You may bleed more easily. Take precautions to avoid injury. Do not skip any scheduled dose or take other medications unless prescribed by the doctor.

Drug-Drug Interactions

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DecitabineLeflunomide
Severe

Drug-Drug Interactions

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DecitabineLeflunomide
Severe
How does the drug interact with Xalibo 50mg Injection:
Combining Xalibo 50mg Injection with Leflunomide can increase the risk of negative side effects.

How to manage the interaction:
Taking Leflunomide with Xalibo 50mg Injection together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms, it's important to contact your doctor right away: infection, complications, fever, chills, diarrhea, sore throat, muscle aches, trouble breathing, losing weight, or pain/burning when you pee. Do not discontinue any medications without consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • After your treatment begins, several dietary adjustments can help you control side effects.
  • Anyone suffering from a chronic illness, including cancer, should consume foods high in protein, healthy fats, whole grains, and vitamins and minerals.
  • Plant-based proteins are among the greatest meals during chemotherapy or other cancer treatments. They have the highest concentrations of vitamins and minerals, such as nuts, seeds, beans and legumes.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

XALIBO 50MG INJECTION Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

XALIBO 50MG INJECTION contains ‘Decitabine’, which works by helping the bone marrow produce normal blood cells and by killing abnormal cells in the bone marrow.

Decitabine therapy should usually be given as a three- or five-day regimen based on your medical condition and response to the treatment. Do not stop taking XALIBO 50MG INJECTION on your own. Do not be reluctant to speak with your doctor if you experience any difficulty while taking XALIBO 50MG INJECTION.

XALIBO 50MG INJECTION can be used to treat blood cancer known as acute myeloid leukemia (AML).

XALIBO 50MG INJECTION therapy may cause a change in skin colour or pale skin or red spots on the skin. Consult your doctor immediately if you notice these symptoms persistently.

XALIBO 50MG INJECTION might cause neutropenia (low white blood cells) and thrombocytopenia (low platelets). Blood count should be checked regularly during treatment with XALIBO 50MG INJECTION.

Decitabine may raise blood sugar. If you have high blood sugar (diabetes), talk with your doctor.

Drug-Drug Interactions Checker List

  • ADALIMUMAB
  • BARICITINIB
  • LEFLUNOMIDE
  • BCG VACCINE
  • DENGUE VACCINE
  • YELLOW FEVER VACCINE
  • CLOZAPINE

Special Advise

  • Regular blood tests are advised before and during treatment with XALIBO 50MG INJECTION.

Disease/Condition Glossary

Myelodysplastic syndromes: Myelodysplastic syndromes are malignancies in which immature blood cells in the bone marrow do not mature and do not become healthy blood cells. Abnormalities in blood cells and bone marrow distinguish the many forms of myelodysplastic syndromes.

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