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Reviewed By Sunny S , MBBS
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Composition :

CAPECITABINE-500MG

Manufacturer/Marketer :

Wembrace Biopharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Xelodace DT 500 Tablet

Xelodace DT 500 Tablet belongs to a group of medicines known as 'anti-cancer' used to treat breast, colon and stomach cancer. Cancer is a condition where cells in a specific body part grow and reproduce uncontrollably. The cancerous cells can attack and destroy surrounding healthy tissue, including organs. Cancer sometimes begins in one body part before spreading to other areas. This process is known as metastasis.

Xelodace DT 500 Tablet contains Capecitabine, an anti-cancer medication that is cytotoxic (causes cell death). When taken, it gets converted into 5-fluorouracil (chemical), which hampers the synthesis of genetic materials (DNA) in the cancer cells, thereby interfering with their growth. As a result, cancer cells' growth is slowed down and eventually killed.

You may experience certain common side-effects such as nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, decreased blood cells (red cells, white cells, and platelets), mouth ulcers, blisters on fingers/feet in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Xelodace DT 500 Tablet , inform your doctor if you have any infection because Xelodace DT 500 Tablet may worsen the infection. Some patients may experience increased sensitivity to light while taking Xelodace DT 500 Tablet ; avoiding prolonged exposure to sunlight is recommended. Inform your doctor if you are pregnant as Xelodace DT 500 Tablet can cause harmful effects on the unborn baby. Both women and men using Xelodace DT 500 Tablet should use birth control to avoid pregnancy. You should not take Xelodace DT 500 Tablet during breastfeeding. Use Xelodace DT 500 Tablet with caution in elderly patients. If you have had leukaemia (blood cancer) and are in remission, do not take live vaccines for three months after your last chemotherapy. You and your surrounding people, such as family members, should not take the polio vaccine.

Uses of Xelodace DT 500 Tablet

Breast cancer, stomach, rectal and colon cancer

Directions for Use

Swallow it as a whole with water; do not crush or chew it.

Medicinal Benefits

Xelodace DT 500 Tablet belongs to the group of anti-cancer medicines. It contains Capecitabine which is cytotoxic (causes cell death). It is used to treat cancer of the colon, breast and stomach. When taken, it gets converted into 5-fluorouracil (chemical), which hampers the synthesis of genetic materials (DNA) in the cancer cells, thereby interfering with their growth. As a result, the growth of cancer cells is slowed down, and eventually, they are killed.

Storage

Store in a cool and dry place away from sunlight
Side effects of Xelodace DT 500 Tablet
  • Apply fragrance-free, thick moisturizing creams to your hands and feet, gently pat the skin and dry instead of rubbing.
  • Use ice packs wrapped in a towel to soothe irritated areas on your palms and soles.
  • Wash your hands and feet with mild, unperfumed soap and avoid using harsh cleaning products.
  • Wear loose-fitting, well-cushioned shoes that provide ample space for your feet.
  • Practice wearing cotton gloves when doing chores that may irritate your hands.
  • Avoid hot baths or showers, instead opt for lukewarm water.
  • Wear sunscreen with a high SPF on exposed skin and limit sun exposure.
  • Don't expose your hands and feet to direct heat like or fireplaces.
  • Reduce pressure by avoiding activities that put pressure on your hands and feet, like jogging or heavy lifting.
  • If required, go for low-impact exercises like walking or swimming.
  • To reduce swelling elevate your feet when resting.
  • Consult your doctor if redness or blistering on your palms or soles, severe pain or discomfort in your hands and feet, open sores or bleeding on your skin or if significant worsening of symptoms.
  • Consult your doctor or healthcare provider before making any changes to your treatment plan or lifestyle modifications related to hand-foot syndrome.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • High levels of bilirubin in blood leads to yellow discolouration of skin and eyes which is a significant liver issue that needs immediate medical attention.
  • Eating a balanced diet can help manage such side effects and must be taken as a dietician suggests.
  • Exercise regularly to maintain a good metabolism in your body.
  • Avoid alcohol consumption as it can affect liver functioning and worsen if there is a yellow discolouration of the skin and eyes.
  • Prevent toxins from chemicals that can be touched and inhaled. Ensure to manage your medications carefully.
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • Know your allergens that cause dermatitis and avoid them.
  • Use fragrance-free detergents and soaps.
  • Apply moisturizer after taking bath to retain moisture in the skin.
  • Apply cool, moist compresses to the rash.
  • Talk to your doctor about creams and ointments to manage your dermatitis.

Drug Warnings

Before taking Xelodace DT 500 Tablet , inform your doctor if you have any infection because Xelodace DT 500 Tablet may worsen the infection. If you have any allergy symptoms, talk to your doctor; inform your doctor if you have a metabolic disorder called DPD (dihydropyrimidine dehydrogenase deficiency), heart problems, bone marrow depression, kidney disease, liver disease, and treatment with chemotherapy or radiation. Some patients may experience increased sensitivity to light while taking Xelodace DT 500 Tablet , and avoiding prolonged exposure to sunlight is recommended. Consult your doctor if you are pregnant as Xelodace DT 500 Tablet can cause harmful effects on the unborn baby. Both women and men using Xelodace DT 500 Tablet should use birth control to avoid pregnancy. The use of Xelodace DT 500 Tablet by either parent may result in congenital disabilities. You should not take Xelodace DT 500 Tablet during breastfeeding. Use Xelodace DT 500 Tablet with caution in elderly patients. If you have had leukaemia (blood cancer) and are in remission, do not take live vaccines for three months after your last chemotherapy. You and your surrounding people, such as family members, should not take the polio vaccine. Avoid smoking or going near naked flames as the fabric (bedding, clothing, dressings) in contact with Xelodace DT 500 Tablet catches fire and burns easily. Washing clothing and bedding may reduce product build-up but not remove it.

Drug-Drug Interactions

verifiedApollotooltip
CapecitabineCertolizumab
Severe
CapecitabineAdalimumab
Severe

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.
  • Get optimal sleep; rest well.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Xelodace DT 500 Tablet Substitute

Substitutes safety advice
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  • Capsy 500 Tablet 10's

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Drug-Diseases Interactions

verifiedApollotooltip
CAPECITABINE-500MGOther and unspecified infectious diseases
Severe
CAPECITABINE-500MGChronic ischaemic heart disease
Severe

Drug-Diseases Interactions

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FAQs

Xelodace DT 500 Tablet interferes with the growth of the cancer cells' genetic material (DNA). This slows the growth of cancer cells and eventually kills them.

Xelodace DT 500 Tablet can make your skin more sensitive to the harmful effects of sunlight. Hence it is advised to wear protective clothing while using Xelodace DT 500 Tablet . It is recommended to avoid tanning booths and sunlamps.

Yes, Xelodace DT 500 Tablet may change the results of blood tests and other laboratory tests. Inform the person doing the tests that you are taking Xelodace DT 500 Tablet as regular monitoring of liver and kidney functions tests, electrolyte levels and blood cells is required.

Xelodace DT 500 Tablet might affect fertility (ability to have children) in both men and women. You may not be able to become pregnant or father a child after treatment with Xelodace DT 500 Tablet . However, it is essential to talk to your doctor before starting treatment with Xelodace DT 500 Tablet if you think you may want to have a baby in the future.

Yes, Xelodace DT 500 Tablet commonly affects the hair by making it thin, which further causes hair loss. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Xelodace DT 500 Tablet . These effects are not long-lasting and may return after some time. If it matters to you, then consult your doctor for further advice.

Xelodace DT 500 Tablet may cause osteoporosis (bone thinning) due to the reduction of estrogen in the body. Regular bone density tests may help you monitor osteoporosis. Contact your doctor if you observe any sign of tendon pain or swelling while taking Xelodace DT 500 Tablet .

Your doctor will decide the number of treatment cycles and the frequency of Xelodace DT 500 Tablet to be taken, depending on the type and stage of the cancer being treated.

No, it is advised not to use these two medicines at the same time as they may cause severe drug reactions. Maintain a gap of at least four weeks between the last dose of brivudine and the first dose of Xelodace DT 500 Tablet .

Drug-Drug Interactions Checker List

  • BEVACIZUMAB
  • CISPLATIN
  • METRONIDAZOLE
  • CALCIUM LEUCOVORIN
  • ALLOPURINOL
  • CIMETIDINE
  • WARFARIN
  • COUMARINS
  • BRIVUDINE
  • SORIVUDINE
  • PHENYTOIN

Special Advise

  • Regularly monitor your blood tests to monitor your liver function, electrolyte levels, and blood cell count in your blood.
  • Avoid unnecessary or prolonged exposure to sunlight and UV light (such as tanning booths) and wear protective clothing, sunglasses, and sunscreen. Xelodace DT 500 Tablet may make your skin sensitive to sunlight.
  • Xelodace DT 500 Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Xelodace DT 500 Tablet .
  • Consult a doctor immediately if you notice any signs of infection, fever, diarrhoea, chills, etc.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and travel to lymph nodes, a primary pathway for the cancer cells to move to other body parts. Symptoms of breast cancer include a lump in the breast or tissue thickening, which feels different than the normal surrounding tissues, breast pain, redness, swelling, and nipple discharge other than breast milk.

Stomach cancer (gastric cancer): It is a type of cancer that develops from the stomach lining. Risk factors may include smoking, a highly processed or salty diet, and severe bacterial infection of H. pylori. Symptoms of stomach cancer include feeling bloated after eating, feeling full after eating small amounts of food, nausea, heartburn or indigestion.

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