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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS

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Manufacturer/Marketer :

Xemex Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Xemtin N 400 mg/10 mg Tablet

Xemtin N 400 mg/10 mg Tablet is a combination medicine indicated for the management of neuropathic pain. It is a chronic progressive nerve disease that causes nerve pain. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

Xemtin N 400 mg/10 mg Tablet contains Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline prolongs the effect of serotonin and noradrenaline and prevents movements of pain signals in the brain.

In some cases, you may experience certain common side-effects such as dizziness, sleepiness, tiredness, headache, nausea, vomiting, blurred vision, dry mouth, and tingling sensations. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Consult your doctor if you are pregnant or breastfeeding. Xemtin N 400 mg/10 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Xemtin N 400 mg/10 mg Tablet should not be given to children unless prescribed by the doctor. Avoid consuming alcohol along with Xemtin N 400 mg/10 mg Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of Xemtin N 400 mg/10 mg Tablet

Neuropathic pain

Directions for Use

Take Xemtin N 400 mg/10 mg Tablet with or without food. Swallow Xemtin N 400 mg/10 mg Tablet as a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Xemtin N 400 mg/10 mg Tablet is used to treat neuropathic pain. Xemtin N 400 mg/10 mg Tablet is a combination of two drugs: Gabapentin and Nortriptyline. Gabapentin belongs to a class of drugs called anti-convulsants whereas Nortriptyline belongs to tricyclic antidepressants. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain and lowers the risk of seizures. On the other hand, Nortriptyline works by preventing the released chemical messenger in brains (serotonin and noradrenaline) from being reabsorbed back into the nerve cells (neuron) in the brain. As a result, it prolongs the effect of serotonin and noradrenaline in the brain and prevents the movement of pain signals in the brain.

Storage

Keep Xemtin N 400 mg/10 mg Tablet out of reach and sight of children.

Drug Warnings

Do not take Xemtin N 400 mg/10 mg Tablet if you are allergic to any of its contents. Inform your doctor before taking Xemtin N 400 mg/10 mg Tablet if you have/had heart problems or bipolar syndrome. Consult your doctor if you are pregnant or breastfeeding. Xemtin N 400 mg/10 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with Xemtin N 400 mg/10 mg Tablet as it could lead to increased dizziness and sleepiness. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Drug-Drug Interactions

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NortriptylinePotassium citrate
Critical

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Diet & Lifestyle Advise

  • Include food rich in vitamins B and D in your diet.
  • Include cayenne pepper in your diet, as it can help lower neuropathic pain.
  • Exercising regularly helps in improving overall health and combating pain. 
  • Rest well, and get plenty of sleep.
  • Try taking a warm bath, as it can be soothing.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Acupuncture can be helpful by stimulating pressure points.
  • Using essential oils for massages can help increase circulation.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT

Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

FAQs

Xemtin N 400 mg/10 mg Tablet contains Gabapentin and Nortriptyline. Gabapentin works by binding to the specific site on voltage-gated calcium channels; this helps in relieving nerve pain. Nortriptyline prolongs the effect of serotonin and noradrenaline and prevents movements of pain signals in the brain.

To treat your condition effectually, continue taking Xemtin N 400 mg/10 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Xemtin N 400 mg/10 mg Tablet ; your doctor will reduce the dose gradually.

Xemtin N 400 mg/10 mg Tablet may cause dry mouth. In that case, you can drink water or fluids, suck hard candy or ice, chew (sugarless) gum, or use a saliva substitute.

Xemtin N 400 mg/10 mg Tablet helps in the treatment of diabetic neuropathy (nerve damage in diabetic patients). However, please consult your doctor before starting Xemtin N 400 mg/10 mg Tablet if you have diabetes.

Drug-Drug Interactions Checker List

  • ZOLPIDEM
  • CITALOPRAM
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  • ESCITALOPRAM
  • FLUOXETINE
  • BUPROPION
  • SERTRALINE
  • CODEINE
  • HYDROCODONE
  • ACETAMINOPHEN
  • OXYCODONE
  • TRAMADOL
  • DIPHENHYDRAMINE
  • CETIRIZINE
  • CYCLOBENZAPRINE
  • CLONAZEPAM
  • PREGABALIN
  • TOPIRAMATE
  • LEVOTHYROXINE SODIUM
  • DIAZEPAM
  • ALPRAZOLAM
  • ONDANSETRON
  • QUETIAPINE
  • NALOXONE
  • BUPRENORPHINE
  • METHADONE

Special Advise

  • If you are taking any antacids containing aluminum or magnesium, try to keep at least 2 hours gap between intake of Xemtin N 400 mg/10 mg Tablet and these antacids to avoid drug-drug interaction.
  • Xemtin N 400 mg/10 mg Tablet can make you feel dizzy or drowsy, try to get up slowly while rising from a sitting or lying position

 

Disease/Condition Glossary

Neuropathic pain: Neuropathic pain is a chronic progressive nerve disease caused due to damage of sensory nerves. The pain could be intermittent or continuous, which is felt as a prickling, stabbing, tingling or burning sensation. A feeling of numbness and loss of sensations is also common with neuropathic pain. Usually, the body sends the pain signals when there is an injury, but with neuropathic pain, the pain is not triggered by an injury, the body unpromptedly sends the pain signals. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events that are usually not painful).

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