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Reviewed By Sureshvarma D , MPharma
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Composition :

EXEMESTANE-25MG

Manufacturer/Marketer :

Celon Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Xmalon 25 mg Tablet

Xmalon 25 mg Tablet belongs to the group of anti-cancer medicines called aromatase inhibitors used to treat breast cancer in women who have gone through menopause (cessation of menses periods). Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen.

Xmalon 25 mg Tablet works by blocking the aromatase enzyme, which produces the estrogen hormone. Thus, it lowers the amount of estrogen (natural female hormone) produced in the body. The cancer cells require estrogen for their growth. Hence, blocking the aromatase enzyme, Xmalon 25 mg Tablet prevents the growth of cancer cells. Together, Xmalon 25 mg Tablet helps prevent or stop the growth of spreading the tumours (cancer cells) to other body parts.

Take Xmalon 25 mg Tablet as prescribed by your doctor. You are advised to take Xmalon 25 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical conditions. In some cases, you may experience common side effects such as insomnia (difficulty sleeping), nausea, headache, musculoskeletal (bone, muscle, or joint) pain, increased sweating, and fatigue. Most of these side effects of Xmalon 25 mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Xmalon 25 mg Tablet should not be taken in conditions like liver and kidney disease. Talk to your doctor before taking Xmalon 25 mg Tablet if you have any type of allergy with Xmalon 25 mg Tablet or any part of Xmalon 25 mg Tablet . If you have not yet gone through menopause, i.e. if you still have periods, then immediately inform your doctor before taking Xmalon 25 mg Tablet . Xmalon 25 mg Tablet should not be taken If you are pregnant or planning to become pregnant or breastfeeding. Xmalon 25 mg Tablet causes weakness and dizziness, so drive only if you are alert. Avoid consuming alcohol with Xmalon 25 mg Tablet as it could lead to increased drowsiness and dizziness. Xmalon 25 mg Tablet should not be given to children as safety has not been established.

Uses of Xmalon 25 mg Tablet

Breast cancer.

Directions for Use

Take Xmalon 25 mg Tablet with or without food. Do not chew or break the tablet; swallow it with a glass of water. Take Xmalon 25 mg Tablet at the same time every day. Xmalon 25 mg Tablet should not be taken unless prescribed by a doctor. Your doctor will advise how long you need to take Xmalon 25 mg Tablet based on your medical condition.

Medicinal Benefits

This Xmalon 25 mg Tablet is used to treat specific types of breast cancer in women after menopause. Xmalon 25 mg Tablet is also used to help avoid cancer from returning. Some breast cancers are made to grow faster by a natural hormone known as estrogen. Xmalon 25 mg Tablet works by blocking the aromatase enzyme, which is involved in producing the estrogen hormone. Therefore, Xmalon 25 mg Tablet lowers the amount of estrogen in the body. Xmalon 25 mg Tablet helps prevent or stop the growth of spreading the tumours (cancer cells) to other body parts.

Storage

Store in a cool and dry place away from sunlight
Side effects of Xmalon 25 mg Tablet
  • Always wear loose-fitting clothes suitable for your activity during hot flashes.
  • Include a diet containing fruits like watermelon, grapes, bananas and green leafy vegetables.
  • Drink plenty of water and stay hydrated.
  • Stay calm and lower your anxiety by practising yoga or meditation.
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
  • Get plenty of rest and avoid activities that tire you out to allow your body fight the infection.
  • Drink lots of fluids to help loosen mucus in the lungs.
  • Use over-the-counter medications like paracetamol or ibuprofen to manage fever.
  • Use a humidifier as it helps soothe irritated airways.
  • Do not make changes to your medication schedule or take over-the-counter medicines without consulting your doctor.
  • Eat more plant based foods like vegetables, fruits and whole grains.
  • Reduce intake of foods containing high fat such as dairy, oil and red meat.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking.
  • Control blood sugar and blood pressure.
  • If you notice any changes in your blood test results, especially if you are taking medicines that can affect clotting time, consult your doctor so that they may adjust the dose or recommend alternative medicine with lower risk.
  • Be aware of possible signs like nosebleeds, easy bruising, or heavy menstrual bleeding.
  • Consult your doctor to determine potential causes of increased PTT (Partial thromboplastin time), such as clotting factor deficiencies or medication effects, and recommend appropriate treatment.
  • Your doctor may adjust medications if they are causing increased PTT.
  • Eat vitamin K-rich foods like leafy greens and essential nutrients to support normal blood clotting.
  • Take precautions like wearing protective gear to prevent injuries.
  • Inform your doctor if you experience severe bleeding, such as heavy periods or bleeding that doesn’t stop after 10–15 minutes of pressure.
  • Be alert for symptoms of bleeding, such as easy bruising, extended bleeding from cuts, gum or nosebleeds, heavy menstrual periods, or blood in your stool or urine.
  • Follow your doctor's advice regarding blood-thinning medications.
  • Limit foods that are high in vitamin K, such as kale, spinach, broccoli, and Brussels sprouts, if your doctor advises.
  • Avoid activities that may lead to injury or increase bleeding risks.
  • If you suspect severe bleeding, seek medical help right away.
  • Follow regular check-ups to assess your blood clotting status and any necessary modifications to your treatment.

Drug Warnings

To treat your condition effectually, continue taking Xmalon 25 mg Tablet for as long as your doctor has prescribed. Do not stop Xmalon 25 mg Tablet midway. Do not take Xmalon 25 mg Tablet if you are allergic to any of its contents. Xmalon 25 mg Tablet should not be taken in conditions like liver and kidney disease. Before taking Xmalon 25 mg Tablet inform your doctor if you have osteoporosis, as Xmalon 25 mg Tablet may increase your risk of developing osteoporosis. If you have not yet gone through menopause, i.e. if you still have periods, then immediately inform your doctor before taking Xmalon 25 mg Tablet . Xmalon 25 mg Tablet should not be taken If you are pregnant or planning to become pregnant or breastfeeding. Xmalon 25 mg Tablet causes weakness and dizziness, so drive only if you are alert. Avoid consuming alcohol with Xmalon 25 mg Tablet as it could lead to increased drowsiness and dizziness. Xmalon 25 mg Tablet should not be given to children as safety has not been established. Xmalon 25 mg Tablet may have an intolerance to some sugar. Inform your doctor before taking this Xmalon 25 mg Tablet .

Drug-Drug Interactions

verifiedApollotooltip
ExemestaneChlorotrianisene
Severe
ExemestaneThalidomide
Severe

Drug-Drug Interactions

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ExemestaneChlorotrianisene
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Co-administration of Xmalon 25 mg Tablet with Chlorotrianisene may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Taking Xmalon 25 mg Tablet with Chlorotrianisene together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ExemestaneThalidomide
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Taking thalidomide together with Xmalon 25 mg Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Xmalon 25 mg Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
ExemestaneEstramustine
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Co-administration of Xmalon 25 mg Tablet with Estramustine may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
There may be a possibility of interaction between Xmalon 25 mg Tablet and Estramustine, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneDienestrol
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Co-administration of Xmalon 25 mg Tablet with Dienestrol may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Xmalon 25 mg Tablet and Dienestrol, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneEstradiol
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Using Estradiol with Xmalon 25 mg Tablet may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Xmalon 25 mg Tablet and Estradiol, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
ExemestaneDiethylstilbestrol
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Co-administration of Xmalon 25 mg Tablet with Diethylstilbestrol may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Taking Xmalon 25 mg Tablet with Diethylstilbestrol together can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.
ExemestaneConjugated Estrogens
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Coadministration of Conjugated estrogens with Xmalon 25 mg Tablet may reduce the effect of Xmalon 25 mg Tablet.

How to manage the interaction:
Although taking Conjugated estrogen and Xmalon 25 mg Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
ExemestaneEthinylestradiol
Severe
How does the drug interact with Xmalon 25 mg Tablet:
When used with Ethinylestradiol, the effectiveness of Xmalon 25 mg Tablet might be reduced.

How to manage the interaction:
Although taking Xmalon 25 mg Tablet and Ethinylestradiol together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
ExemestaneEstrone
Severe
How does the drug interact with Xmalon 25 mg Tablet:
Co-administration of Xmalon 25 mg Tablet with Estrone may interfere with Xmalon 25 mg Tablet's activity and make it less effective in treating the condition.

How to manage the interaction:
Co-administration of Xmalon 25 mg Tablet with Estrone can result in an interaction, but it can be taken if a doctor has advised it. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices in your diet.
  • Avoid fast, fried, processed meats, refined carbs, and added sugar.
  • Get optimal sleep, rest well.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Xmalon 25 mg Tablet Substitute

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

The most common side effects of using Xmalon 25 mg Tablet are hot flashes, joint pain, feeling tired, trouble sleeping, headache, depression, increased sweating, upset stomach, feeling anxiety, and difficulty in breathing. If any of these side effects disturb you, inform your doctor.

The common symptoms of breast cancer involve the presence of a lump in the breasts that feels dissimilar from the rest of the breast tissue. You may observe changes in the size, shape and appearance of the breast. The nipple becomes enlarged and painful, and discharge is also one of the symptoms of breast cancer. Pain occurs around the breast.

Yes, Xmalon 25 mg Tablet commonly affects the hair by making them thin, which further causes loss of hair. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of Xmalon 25 mg Tablet . These effects are not long-lasting and may return after some time. If it matters to you, inform your doctor of another alternative medicine to avoid harm to hair.

Xmalon 25 mg Tablet causes dizziness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel dizzy or drowsy.

Although there is no known way to prevent breast cancer, there are ways to lower your risk. It is advisable to drink less alcohol, stay at a healthy weight, get regular exercise, breastfeed (completely breastfeeding during your baby's first 6 months and continuing for 12 months or longer), and inform your doctor about hormone replacement therapy (a form of hormone therapy used to treat symptoms related with female menopause) if you take it.

Drug-Drug Interactions Checker List

  • RIFAMPICIN
  • CARBAMAZEPINE
  • PHENYTOIN

Special Advise

  • Your doctor may advise you to regularly measure body density before, during and after the treatment as Xmalon 25 mg Tablet may cause bone thinning due to the reduction of estrogens in the body.
  • Xmalon 25 mg Tablet should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Xmalon 25 mg Tablet .

Disease/Condition Glossary

Breast cancer is a type of cancer that develops in breast cells stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), fatty tissue, or fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. Symptoms of breast cancer include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm.

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