Xultophy Injection 3 ml

Written By Santoshini Reddy G , M Pharmacy

Reviewed By Hari Kumar , MBBS

Prescription drug

MRP ₹5376.5

(Inclusive of all Taxes)

₹806.5 Cashback (15%)

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Whats That

About Xultophy 3ml Pre-Filled Pen

Xultophy 3ml Pre-Filled Pen belongs to the group of anti-diabetic medicines used to treat type-2 diabetes mellitus adjunct to diet and exercise. Type-2 diabetes mellitus is also known as non-insulin-dependent diabetes or adult-onset diabetes. It is a medical condition in which blood glucose levels are above normal due to insulin deficiency, insulin resistance, or both.

Xultophy 3ml Pre-Filled Pen is a combination of two drugs, namely: Liraglutide and Insulin degludec. Liraglutide lowers the amount of sugar made by the body and helps the body make more insulin during meals. Insulin degludec works in a similar manner as the insulin produced by the body. It lowers blood glucose levels and facilitates the reuptake of glucose in the fat and muscle cells. Together, Xultophy 3ml Pre-Filled Pen helps in controlling the blood glucose levels.

You are advised to use Xultophy 3ml Pre-Filled Pen for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as hypoglycaemia (low blood glucose levels), injection site reactions, nausea, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are recommended to consult your doctor if the side effects persist or worsen.

Do not skip any doses or stop taking Xultophy 3ml Pre-Filled Pen suddenly without consulting your doctor, as it may lead to increased blood glucose levels. Consult your doctor if you are pregnant or breastfeeding. Xultophy 3ml Pre-Filled Pen is not recommended for children below 18 years. Avoid alcohol consumption as it might affect blood sugar levels. Xultophy 3ml Pre-Filled Pen may cause hypoglycaemia, so drive only if you are alert. Inform your doctor about all the medications you are taking and your health condition to rule out any unpleasant side effects/interactions.

Uses of Xultophy 3ml Pre-Filled Pen

Type-2 diabetes mellitus

Directions for Use

Xultophy 3ml Pre-Filled Pen should be administered sub-cutaneous only. Wash your hands properly and adjust the dose as advised by the doctor. Clean the injection site and inject the dose subcutaneously in the abdomen/thighs/upper arm. Safely discard the needle.

Medicinal Benefits

Xultophy 3ml Pre-Filled Pen is a combination of two anti-diabetic drugs, namely: Liraglutide and Insulin degludec. Xultophy 3ml Pre-Filled Pen is used to treat type-2 diabetes mellitus adjunct to diet and exercise. Liraglutide lowers the amount of sugar made by the body and helps the body make more insulin during meals. Insulin degludec works similarly as the insulin produced by the body. It lowers blood glucose levels and facilitates the reuptake of glucose in the fat and muscle cells. Together, Xultophy 3ml Pre-Filled Pen helps in controlling blood glucose levels.

Storage

Keep Xultophy 3ml Pre-Filled Pen out of reach and sight of children.

Side effects of Xultophy Injection 3 ml

Drug Warnings

Do not use Xultophy 3ml Pre-Filled Pen if you are allergic to any of its contents. Inform your doctor if you have type 1 diabetes, diabetic ketoacidosis, inflammatory bowel disease, delayed gastric emptying, eye problems, thyroid problems, kidney/liver problems or if you are taking any oral anti-diabetic medicines. Consult your doctor if you are pregnant or breastfeeding. Xultophy 3ml Pre-Filled Pen is not recommended for children below 18 years. Xultophy 3ml Pre-Filled Pen may cause hypoglycaemia, so drive only if you are alert. Do not use Xultophy 3ml Pre-Filled Pen if the pen is damaged, if the solution is not clear or if the pen has not been stored properly.

Drug-Drug Interactions

LiraglutideGatifloxacin

Critical

Insulin degludecEnoxacin

Severe

Drug-Drug Interactions

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LiraglutideGatifloxacin

Critical

How does the drug interact with Xultophy Injection 3 ml:
Coadministration of Xultophy Injection 3 ml with Gatifloxacin may sometimes affect blood glucose levels.

How to manage the interaction:
Xultophy Injection 3 ml with Gatifloxacin can cause an interaction but can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.

Insulin degludecEnoxacin

Severe

How does the drug interact with Xultophy Injection 3 ml:
Taking Xultophy Injection 3 ml with Enoxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia(low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Xultophy Injection 3 ml and cinoxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Insulin degludecTrovafloxacin

Severe

How does the drug interact with Xultophy Injection 3 ml:
Taking Xultophy Injection 3 ml with trovafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia less frequently.

How to manage the interaction:
There could be a possible interaction between Xultophy Injection 3 ml and trovafloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Insulin degludecGrepafloxacin

Severe

How does the drug interact with Xultophy Injection 3 ml:
Taking Xultophy Injection 3 ml with grepafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Xultophy Injection 3 ml and grepafloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Insulin degludecNalidixic acid

Severe

How does the drug interact with Xultophy Injection 3 ml:
Taking Xultophy Injection 3 ml with nalidixic acid affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Xultophy Injection 3 ml and nalidixic but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Insulin degludecNorfloxacin

Severe

How does the drug interact with Xultophy Injection 3 ml:
Taking Xultophy Injection 3 ml with norfloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Xultophy Injection 3 ml and norfloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Insulin degludecMoxifloxacin

Severe

How does the drug interact with Xultophy Injection 3 ml:
Taking Xultophy Injection 3 ml with Moxifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Xultophy Injection 3 ml and Moxifloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience headache, dizziness, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, and increased urination. Do not stop using any medications without talking to a doctor.

Insulin degludecGatifloxacin

Severe

How does the drug interact with Xultophy Injection 3 ml:
Taking Xultophy Injection 3 ml with Gatifloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia less frequently.

How to manage the interaction:
There could be a possible interaction between insulin aspart and Gatifloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience symptoms of hypoglycemia, which include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat, or symptoms of hyperglycemia which may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without first talking to your doctor.

Insulin degludecSparfloxacin

Severe

How does the drug interact with Xultophy Injection 3 ml:
Taking Xultophy Injection 3 ml with sparfloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia less frequently.

How to manage the interaction:
There could be a possible interaction between Xultophy Injection 3 ml and sparfloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Insulin degludecOfloxacin

Severe

How does the drug interact with Xultophy Injection 3 ml:
Taking Xultophy Injection 3 ml with ofloxacin affects blood glucose levels, which may cause hyperglycemia (high blood glucose) and hypoglycemia (low blood glucose) less frequently.

How to manage the interaction:
There could be a possible interaction between Xultophy Injection 3 ml and ofloxacin but can be taken if prescribed by a doctor. However, consult the doctor immediately if you experience hypoglycemia or hyperglycemia. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, hunger, weakness, sweating, palpitation, and rapid heartbeat. Symptoms of hyperglycemia may include increased thirst, increased hunger, and increased urination. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Include foods rich in healthy carbohydrates and fibre, fruits, whole grains, and vegetables in your diet.
Try eating food at regular intervals. Do not skip meals. Also, try not to overeat.
Follow a healthy diet and walk for at least 45 minutes to complement treatment with Xultophy 3ml Pre-Filled Pen.
Maintain a healthy weight by exercising regularly.
Rest properly, avoid stress by doing meditation or yoga.

Side Effects of Xultophy 3ml Pre-Filled Pen

Hypoglycaemia (low blood glucose levels)
Injection site reactions
Nausea
Vomiting
Diarrhoea
Constipation

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:40 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Xultophy 3ml Pre-Filled Pen work?

Xultophy 3ml Pre-Filled Pen contains Liraglutide and Insulin degludec. Liraglutide lowers the amount of sugar made by the body and helps the body make more insulin during meals. Insulin degludec works similarly to the insulin produced by the body. It lowers blood glucose levels and facilitates the reuptake of glucose in the fat and muscle cells. Together, Xultophy 3ml Pre-Filled Pen helps in controlling blood glucose levels.

Does Xultophy 3ml Pre-Filled Pen cause hypoglycaemia (low blood glucose levels)?

Xultophy 3ml Pre-Filled Pen may sometimes lower the blood glucose levels more than normal, leading to hypoglycaemia. Regularly monitor your blood sugar levels while taking Xultophy 3ml Pre-Filled Pen. Always carry any sugary food and consume it if you experience hypoglycaemia symptoms such as headache, drowsiness, cold sweat, feeling sick, unusual tiredness or weakness, and visual disturbances.

When does Xultophy 3ml Pre-Filled Pen cause hypoglycaemia?

Hypoglycaemia may occur following prolonged or severe exercise, during illness, alcohol consumption, low food intake, or when Xultophy 3ml Pre-Filled Pen is taken along with other antidiabetic medicines.

How to prevent hypoglycaemia?

Maintain a healthy diet by regular intake of carbohydrates such as bread and products containing starch and sugar. Eat your meals regularly, and do not exercise heavily for longer durations with an empty stomach.

Can I stop using Xultophy 3ml Pre-Filled Pen on my own?

Do not stop using Xultophy 3ml Pre-Filled Pen without consulting your doctor as it may cause an increase in blood glucose levels. Continue taking Xultophy 3ml Pre-Filled Pen for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while using Xultophy 3ml Pre-Filled Pen.

How to store Xultophy 3ml Pre-Filled Pen?

Before opening, store Xultophy 3ml Pre-Filled Pen in a refrigerator at 2°C to 8°C. Do not freeze. During use, you can keep Xultophy 3ml Pre-Filled Pen at room temperature (below 30°C) or in a refrigerator (2°C to 8°C) for up to 21 days. The product should be thrown away 21 days after the first opening. Always keep the cap of the pre-filled syringe on to protect it from the light.

Drug-Drug Interactions Checker List

WARFARIN
PIOGLITAZONE
OCTREOTIDE
EPINEPHRINE
SALBUTAMOL
TERBUTALINE
DANAZOL
TESTOSTERONE
ASPIRIN

Special Advise

Regularly monitor blood glucose levels while taking Xultophy 3ml Pre-Filled Pen.
Try not to skip any doses and take Xultophy 3ml Pre-Filled Pen for as long as your doctor has prescribed it for you.
To avoid contamination, always use a new needle for each injection.
Rotate the injection site to prevent changes to the fatty tissue under the skin like skin thickening, skin lumps or shrinking under the skin.

Disease/Condition Glossary

Type-2 diabetes mellitus: It is also known as non-insulin-dependent diabetes. It is a chronic or lifelong disease that keeps the body from utilizing insulin properly. Diabetes is a medical condition in which blood glucose levels are above normal. People with type 2 diabetes either do not produce enough insulin, or the insulin produced cannot perform its function in the body (insulin resistance). Middle-aged or older individuals are most likely to suffer from type 2 diabetes; hence, it is also known as adult-onset diabetes. Type 2 diabetes symptoms include lack of energy, tiredness, frequent urination, excess thirst, dry mouth, blurry vision, constant hunger, weight loss, and itchy skin.